Result of FASTA (ccds) for
pF1KA0054
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0054, 1942 aa
1>>>pF1KA0054 1942 - 1942 aa - 1942 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6730+/-0.00129; mu= -4.1850+/- 0.077
mean_var=350.2762+/-72.967, 0's: 0 Z-trim(112.0): 57 B-trim: 294 in 1/51
Lambda= 0.068528
statistics sampled from 12752 (12793) to 12752 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.393), width: 16
Scan time: 4.220
The best scores are: opt bits E(32554)
CCDS42374.1 HELZ gene_id:9931|Hs108|chr17 (1942) 13188 1319.5 0
CCDS82192.1 HELZ gene_id:9931|Hs108|chr17 (1943) 13176 1318.4 0
CCDS33508.1 HELZ2 gene_id:85441|Hs108|chr20 (2649) 1101 124.6 5e-27
CCDS13527.1 HELZ2 gene_id:85441|Hs108|chr20 (2080) 769 91.7 3.2e-17
>>CCDS42374.1 HELZ gene_id:9931|Hs108|chr17 (1942 aa)
initn: 13188 init1: 13188 opt: 13188 Z-score: 7058.8 bits: 1319.5 E(32554): 0
Smith-Waterman score: 13188; 99.9% identity (100.0% similar) in 1942 aa overlap (1-1942:1-1942)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 LDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 IGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPES
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 RPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 NQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 QSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIH
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 GSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWK
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS42 GSVALETLRQQQARFQQWSEHHAFLSQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRADWK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 PPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 GAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSS
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 PESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 QHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPL
1870 1880 1890 1900 1910 1920
1930 1940
pF1KA0 SLFQELSLGSSSGSNGFYSYFK
::::::::::::::::::::::
CCDS42 SLFQELSLGSSSGSNGFYSYFK
1930 1940
>>CCDS82192.1 HELZ gene_id:9931|Hs108|chr17 (1943 aa)
initn: 8658 init1: 8658 opt: 13176 Z-score: 7052.4 bits: 1318.4 E(32554): 0
Smith-Waterman score: 13176; 99.9% identity (99.9% similar) in 1943 aa overlap (1-1942:1-1943)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
610 620 630 640 650 660
670 680 690 700 710
pF1KA0 LPPVLIIGPYGTGKTFTLAQAVKHILQQQET-RILICTHSNSAADLYIKDYLHPYVEAGN
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS82 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGN
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 PQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLC
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 QLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERN
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 LHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 LTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 VFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDS
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 TEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHG
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA0 ITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQND
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA0 HFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVY
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA0 GGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA0 TIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPE
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA0 SRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTL
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA0 LNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHR
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA0 PQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRI
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA0 HGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADW
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS82 HGSVALETLRQQQARFQQWSEHHAFLSQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRADW
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA0 KLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVP
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA0 SPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAP
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA0 DGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSS
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA0 SSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFS
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA0 SPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSV
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA0 LQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDP
1870 1880 1890 1900 1910 1920
1920 1930 1940
pF1KA0 LSLFQELSLGSSSGSNGFYSYFK
:::::::::::::::::::::::
CCDS82 LSLFQELSLGSSSGSNGFYSYFK
1930 1940
>>CCDS33508.1 HELZ2 gene_id:85441|Hs108|chr20 (2649 aa)
initn: 1199 init1: 406 opt: 1101 Z-score: 598.6 bits: 124.6 E(32554): 5e-27
Smith-Waterman score: 1683; 33.8% identity (61.8% similar) in 940 aa overlap (166-1086:76-952)
140 150 160 170 180 190
pF1KA0 KTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEEYTLCKRFLEQGICRY
:. : :: :.. .. :: . .:.:
CCDS33 LVTCHSQEAFENHCASSEHAQMVAFDQALPWEHRSPPPGLS---KFELCPK---PDLCEY
50 60 70 80 90
200 210 220 230 240 250
pF1KA0 GAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLIEKWMNSLSPEKVLSE
: ::.::: .:: :: .: .. ..:. : .. :.: :. ... : : ::.:
CCDS33 GDACTKAHSAQELQEWVRR--TQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 CIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAG
..::.: : : .. .:.. .::::. . : .:::: . ::..: .
CCDS33 TLDGVRVTCNQPLMYQAQERKTQYSWTFAVHSEEP--LLHVALLKQEPGADFSLVAPGLP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 DSTTQVSQE---VPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLE
. . : :: . . ..::. .. ::::.: .::::: .
CCDS33 PGRLYARGERFRVPSSTAD---------------FQVGVRVQAASFGTFEQWVVFDFGRR
220 230 240 250 260
380 390 400 410 420 430
pF1KA0 PVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPN-ETTDLEKSLLIR
:::.:.. .. .. . . .:: .... .. :. : : . .:. .
CCDS33 PVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRHVV---PGVERTAEQTALMAK
270 280 290 300 310
440 450 460 470 480 490
pF1KA0 YQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFM
:. : : .. .:: . .. .::..:.:..:: :: :: . ..:..:. :. . ....
CCDS33 YKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQLVAKLTLRGQVFLKTALQ
320 330 340 350 360 370
500 510 520 530 540 550
pF1KA0 LTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTK
... .: : :... . .: :: : :. :... . ::: .
CCDS33 TPALN--MLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALVAPVP--------APD
380 390 400 410 420
560 570 580 590 600
pF1KA0 EKVYEATIEEK--TKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDR
. :.:. .:.. ... ..: : .:: :.:.:. .:.:::.. . . : :.:
CCDS33 NTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDT
430 440 450 460 470 480
610 620 630 640 650 660
pF1KA0 IKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITT--PL-AIQLPPVLI
. .. .. ::. : ..: : :. : : ::. :: :. : . ..::.::
CCDS33 LPEEQLVVPDLP-TCALP----RPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPLLI
490 500 510 520 530 540
670 680 690 700 710 720
pF1KA0 IGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLR
::.:::::.:::.: ..... ::..:::::.:::::.::..:.: .: .:.:.: :::
CCDS33 YGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLR
550 560 570 580 590 600
730 740 750 760 770 780
pF1KA0 VYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPG
:.. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :
CCDS33 VMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVG
610 620 630 640 650
790 800 810 820 830 840
pF1KA0 FFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLD
::.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .::
CCDS33 FFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLH
660 670 680 690 700 710
850 860 870 880 890
pF1KA0 RLYEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFY
::. : : :... :::: .::... :. :: .: . : :: : : :
CCDS33 RLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHY
720 730 740 750 760 770
900 910 920 930 940 950
pF1KA0 PLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYAD
:: : . : .. . ... : ::. .:::.:.: :: :: .. : ::. ..
CCDS33 PLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGA
780 790 800 810 820 830
960 970 980 990 1000 1010
pF1KA0 QVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLED
:: .: :::.. :..:.: . :.::::. :::: :::. .: .
CCDS33 QVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE----
840 850 860 870 880 890
1020 1030 1040 1050 1060 1070
pF1KA0 STEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL-
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :.
CCDS33 --------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVC
900 910 920 930 940
1080 1090 1100 1110 1120 1130
pF1KA0 -HGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHT
.:...::..
CCDS33 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGD
950 960 970 980 990 1000
>>CCDS13527.1 HELZ2 gene_id:85441|Hs108|chr20 (2080 aa)
initn: 905 init1: 229 opt: 769 Z-score: 422.8 bits: 91.7 E(32554): 3.2e-17
Smith-Waterman score: 930; 40.7% identity (66.3% similar) in 398 aa overlap (699-1086:6-383)
670 680 690 700 710 720
pF1KA0 PYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
: ::::.::..:.: .: .:.:.: ::::.
CCDS13 MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
10 20 30
730 740 750 760 770 780
pF1KA0 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :::
CCDS13 YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
40 50 60 70 80 90
790 800 810 820 830 840
pF1KA0 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .:: ::
CCDS13 SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
100 110 120 130 140 150
850 860 870 880 890 900
pF1KA0 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
. : : :... :::: .::... :. :: .: . : :: : : :::
CCDS13 FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
160 170 180 190 200 210
910 920 930 940 950 960
pF1KA0 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
: . : .. . ... : ::. .:::.:.: :: :: .. : ::. .. ::
CCDS13 MFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGAQV
220 230 240 250 260 270
970 980 990 1000 1010 1020
pF1KA0 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
.: :::.. :..:.: . :.::::. :::: :::. .: .
CCDS13 SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
280 290 300 310 320
1030 1040 1050 1060 1070
pF1KA0 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :. .
CCDS13 ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
330 340 350 360 370
1080 1090 1100 1110 1120 1130
pF1KA0 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
:...::..
CCDS13 GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
380 390 400 410 420 430
1942 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 17:57:41 2016 done: Wed Nov 2 17:57:42 2016
Total Scan time: 4.220 Total Display time: 0.280
Function used was FASTA [36.3.4 Apr, 2011]