Result of FASTA (omim) for
pF1KA0059
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0059, 718 aa
1>>>pF1KA0059 718 - 718 aa - 718 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4309+/-0.000404; mu= 8.0559+/- 0.025
mean_var=267.6432+/-56.540, 0's: 0 Z-trim(119.9): 423 B-trim: 0 in 0/55
Lambda= 0.078396
statistics sampled from 34007 (34443) to 34007 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.404), width: 16
Scan time: 12.730
The best scores are: opt bits E(85289)
NP_001003407 (OMIM: 602330) actin-binding LIM prot ( 718) 5054 585.6 2.4e-166
NP_002304 (OMIM: 602330) actin-binding LIM protein ( 778) 4912 569.5 1.7e-161
XP_011538105 (OMIM: 602330) PREDICTED: actin-bindi ( 765) 4911 569.4 1.8e-161
XP_016871744 (OMIM: 602330) PREDICTED: actin-bindi ( 703) 4900 568.1 4.1e-161
XP_016871735 (OMIM: 602330) PREDICTED: actin-bindi ( 760) 3831 447.3 1.1e-124
XP_016871737 (OMIM: 602330) PREDICTED: actin-bindi ( 619) 3697 432.0 3.4e-120
XP_005269881 (OMIM: 602330) PREDICTED: actin-bindi ( 655) 3271 383.8 1.1e-105
NP_001309815 (OMIM: 602330) actin-binding LIM prot ( 654) 3268 383.5 1.4e-105
XP_016871742 (OMIM: 602330) PREDICTED: actin-bindi ( 718) 3265 383.2 1.9e-105
XP_016871736 (OMIM: 602330) PREDICTED: actin-bindi ( 619) 3227 378.8 3.4e-104
XP_016871748 (OMIM: 602330) PREDICTED: actin-bindi ( 464) 3116 366.1 1.7e-100
XP_016871747 (OMIM: 602330) PREDICTED: actin-bindi ( 464) 3116 366.1 1.7e-100
NP_001003408 (OMIM: 602330) actin-binding LIM prot ( 746) 3058 359.8 2.2e-98
XP_016871733 (OMIM: 602330) PREDICTED: actin-bindi ( 793) 3058 359.8 2.3e-98
NP_001309816 (OMIM: 602330) actin-binding LIM prot ( 636) 3043 358.0 6.4e-98
NP_001309812 (OMIM: 602330) actin-binding LIM prot ( 683) 3040 357.7 8.5e-98
XP_016871739 (OMIM: 602330) PREDICTED: actin-bindi ( 743) 2922 344.4 9.4e-94
XP_016871745 (OMIM: 602330) PREDICTED: actin-bindi ( 669) 2908 342.8 2.6e-93
NP_001309813 (OMIM: 602330) actin-binding LIM prot ( 668) 2905 342.5 3.3e-93
XP_016871740 (OMIM: 602330) PREDICTED: actin-bindi ( 732) 2902 342.2 4.5e-93
NP_001309814 (OMIM: 602330) actin-binding LIM prot ( 666) 2900 341.9 4.9e-93
XP_016871741 (OMIM: 602330) PREDICTED: actin-bindi ( 730) 2897 341.6 6.6e-93
NP_001309817 (OMIM: 602330) actin-binding LIM prot ( 455) 2444 290.1 1.3e-77
XP_006717900 (OMIM: 602330) PREDICTED: actin-bindi ( 788) 2236 266.9 2.2e-70
NP_055760 (OMIM: 611305) actin-binding LIM protein ( 683) 2234 266.6 2.4e-70
NP_001287944 (OMIM: 611305) actin-binding LIM prot ( 683) 2234 266.6 2.4e-70
NP_001309811 (OMIM: 602330) actin-binding LIM prot ( 748) 2231 266.3 3.2e-70
XP_016871746 (OMIM: 602330) PREDICTED: actin-bindi ( 522) 2199 262.5 3.1e-69
XP_016871743 (OMIM: 602330) PREDICTED: actin-bindi ( 711) 2199 262.6 3.8e-69
XP_016871734 (OMIM: 602330) PREDICTED: actin-bindi ( 771) 2096 251.0 1.3e-65
XP_011538104 (OMIM: 602330) PREDICTED: actin-bindi ( 772) 2093 250.7 1.6e-65
XP_011538103 (OMIM: 602330) PREDICTED: actin-bindi ( 801) 2093 250.7 1.7e-65
XP_016871738 (OMIM: 602330) PREDICTED: actin-bindi ( 746) 2088 250.1 2.3e-65
XP_016871732 (OMIM: 602330) PREDICTED: actin-bindi ( 795) 2088 250.1 2.4e-65
XP_016864206 (OMIM: 612544) PREDICTED: actin-bindi ( 588) 2076 248.6 5.1e-65
XP_016864205 (OMIM: 612544) PREDICTED: actin-bindi ( 589) 2076 248.6 5.1e-65
XP_016864199 (OMIM: 612544) PREDICTED: actin-bindi ( 627) 2076 248.7 5.3e-65
XP_016864198 (OMIM: 612544) PREDICTED: actin-bindi ( 628) 2076 248.7 5.3e-65
XP_016864207 (OMIM: 612544) PREDICTED: actin-bindi ( 583) 2073 248.3 6.4e-65
XP_016871731 (OMIM: 602330) PREDICTED: actin-bindi ( 833) 2067 247.8 1.3e-64
XP_011538107 (OMIM: 602330) PREDICTED: actin-bindi ( 696) 2049 245.7 4.8e-64
XP_005269884 (OMIM: 602330) PREDICTED: actin-bindi ( 504) 2028 243.1 2e-63
XP_006717910 (OMIM: 602330) PREDICTED: actin-bindi ( 504) 2028 243.1 2e-63
XP_005269883 (OMIM: 602330) PREDICTED: actin-bindi ( 532) 2028 243.2 2.1e-63
XP_006717909 (OMIM: 602330) PREDICTED: actin-bindi ( 532) 2028 243.2 2.1e-63
NP_006711 (OMIM: 602330) actin-binding LIM protein ( 455) 1995 239.3 2.5e-62
XP_011535911 (OMIM: 611305) PREDICTED: actin-bindi ( 445) 1931 232.1 3.7e-60
XP_005248078 (OMIM: 612544) PREDICTED: actin-bindi ( 622) 1910 229.9 2.4e-59
XP_005248075 (OMIM: 612544) PREDICTED: actin-bindi ( 661) 1910 229.9 2.5e-59
XP_016864212 (OMIM: 612544) PREDICTED: actin-bindi ( 555) 1907 229.5 2.8e-59
>>NP_001003407 (OMIM: 602330) actin-binding LIM protein (718 aa)
initn: 5054 init1: 5054 opt: 5054 Z-score: 3107.5 bits: 585.6 E(85289): 2.4e-166
Smith-Waterman score: 5054; 99.7% identity (100.0% similar) in 718 aa overlap (1-718:1-718)
10 20 30 40 50 60
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSGREEDDEELLRRR
::::::::::::::::::::::.::::::::::::::.::::::::::::::::::::::
NP_001 SEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEM
610 620 630 640 650 660
670 680 690 700 710
pF1KA0 LMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
670 680 690 700 710
>>NP_002304 (OMIM: 602330) actin-binding LIM protein 1 i (778 aa)
initn: 4911 init1: 4911 opt: 4912 Z-score: 3020.3 bits: 569.5 E(85289): 1.7e-161
Smith-Waterman score: 4912; 99.4% identity (99.7% similar) in 700 aa overlap (19-718:79-778)
10 20 30 40
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKG
: :::::::::::::::::::::::::::
NP_002 FTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEPCKG
50 60 70 80 90 100
50 60 70 80 90 100
pF1KA0 EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGE
110 120 130 140 150 160
110 120 130 140 150 160
pF1KA0 VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAG
170 180 190 200 210 220
170 180 190 200 210 220
pF1KA0 CGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEAC
230 240 250 260 270 280
230 240 250 260 270 280
pF1KA0 HQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRP
290 300 310 320 330 340
290 300 310 320 330 340
pF1KA0 TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP
350 360 370 380 390 400
350 360 370 380 390 400
pF1KA0 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP
410 420 430 440 450 460
410 420 430 440 450 460
pF1KA0 TTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIY
470 480 490 500 510 520
470 480 490 500 510 520
pF1KA0 KQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSG
::::::::::::::::::::::::::::::::::.::::::::::::::.::::::::::
NP_002 KQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSG
530 540 550 560 570 580
530 540 550 560 570 580
pF1KA0 REEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 REEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHI
590 600 610 620 630 640
590 600 610 620 630 640
pF1KA0 PSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMP
650 660 670 680 690 700
650 660 670 680 690 700
pF1KA0 NMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRR
710 720 730 740 750 760
710
pF1KA0 NDMKKKAKLF
::::::::::
NP_002 NDMKKKAKLF
770
>>XP_011538105 (OMIM: 602330) PREDICTED: actin-binding L (765 aa)
initn: 4911 init1: 4911 opt: 4911 Z-score: 3019.8 bits: 569.4 E(85289): 1.8e-161
Smith-Waterman score: 4911; 99.7% identity (100.0% similar) in 697 aa overlap (22-718:69-765)
10 20 30 40 50
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVL
::::::::::::::::::::::::::::::
XP_011 EPHGWREEEDQDLRRRRGESHRKKKEQPAGVAHPQDPHHPSEKPVIHCHKCGEPCKGEVL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KA0 RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVT
100 110 120 130 140 150
120 130 140 150 160 170
pF1KA0 ALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGR
160 170 180 190 200 210
180 190 200 210 220 230
pF1KA0 DIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQF
220 230 240 250 260 270
240 250 260 270 280 290
pF1KA0 ITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRT
280 290 300 310 320 330
300 310 320 330 340 350
pF1KA0 SSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYT
340 350 360 370 380 390
360 370 380 390 400 410
pF1KA0 SGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTS
400 410 420 430 440 450
420 430 440 450 460 470
pF1KA0 RSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH
460 470 480 490 500 510
480 490 500 510 520 530
pF1KA0 AALAAQSKSSEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSGREE
:::::::::::::::::::::::::::::::.::::::::::::::.:::::::::::::
XP_011 AALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREE
520 530 540 550 560 570
540 550 560 570 580 590
pF1KA0 DDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSS
580 590 600 610 620 630
600 610 620 630 640 650
pF1KA0 KTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNML
640 650 660 670 680 690
660 670 680 690 700 710
pF1KA0 EPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDM
700 710 720 730 740 750
pF1KA0 KKKAKLF
:::::::
XP_011 KKKAKLF
760
>>XP_016871744 (OMIM: 602330) PREDICTED: actin-binding L (703 aa)
initn: 3445 init1: 3276 opt: 4900 Z-score: 3013.5 bits: 568.1 E(85289): 4.1e-161
Smith-Waterman score: 4900; 99.3% identity (99.7% similar) in 700 aa overlap (21-718:4-703)
10 20 30 40 50 60
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
.:::::::::::::::::::::::::::::::::::::::
XP_016 MSARVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
10 20 30 40
70 80 90 100 110 120
pF1KA0 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
350 360 370 380 390 400
430 440 450 460 470
pF1KA0 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH--AALAAQS
::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHDAAALAAQS
410 420 430 440 450 460
480 490 500 510 520 530
pF1KA0 KSSEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSGREEDDEELLR
::::::::::::::::::::::::.::::::::::::::.::::::::::::::::::::
XP_016 KSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLR
470 480 490 500 510 520
540 550 560 570 580 590
pF1KA0 RRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPG
530 540 550 560 570 580
600 610 620 630 640 650
pF1KA0 YGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPY
590 600 610 620 630 640
660 670 680 690 700 710
pF1KA0 EMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
650 660 670 680 690 700
>>XP_016871735 (OMIM: 602330) PREDICTED: actin-binding L (760 aa)
initn: 3629 init1: 1997 opt: 3831 Z-score: 2359.7 bits: 447.3 E(85289): 1.1e-124
Smith-Waterman score: 4494; 90.8% identity (91.1% similar) in 727 aa overlap (22-718:69-760)
10 20 30 40 50
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVL
::::::::::::::::::::::::::::::
XP_016 EPHGWREEEDQDLRRRRGESHRKKKEQPAGVAHPQDPHHPSEKPVIHCHKCGEPCKGEVL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KA0 RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVT
100 110 120 130 140 150
120 130 140 150 160 170
pF1KA0 ALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGR
160 170 180 190 200 210
180 190 200 210 220 230
pF1KA0 DIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQF
220 230 240 250 260 270
240 250 260 270 280
pF1KA0 ITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLR----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNI
280 290 300 310 320 330
290 300 310 320
pF1KA0 ------------------------PTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDY
::::::::::::::::::::::::::::::::::::
XP_016 RRSSSDFFYSKSLIRRTGRSPSLQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDY
340 350 360 370 380 390
330 340 350 360 370 380
pF1KA0 KDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVR
400 410 420 430 440 450
390 400 410 420 430 440
pF1KA0 DRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTP
:::::::::::::::::::::::::::::::::::::
XP_016 DRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP-----------------------
460 470 480 490
450 460 470 480 490 500
pF1KA0 TYAQAPKHFHVPDQGINIYRKPPIYKQH--AALAAQSKSSEDIIKFSKFPAAQAPDPSET
:::::::::::::::: ::::::::::::::::::::::::::::::
XP_016 ------------DQGINIYRKPPIYKQHDAAALAAQSKSSEDIIKFSKFPAAQAPDPSET
500 510 520 530 540
510 520 530 540 550 560
pF1KA0 PEIETDHWPGPPSFAVIGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKE
:.::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 PKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKE
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 EMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDV
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 SGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLE
670 680 690 700 710 720
690 700 710
pF1KA0 RHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
:::::::::::::::::::::::::::::::::::::
XP_016 RHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
730 740 750 760
>>XP_016871737 (OMIM: 602330) PREDICTED: actin-binding L (619 aa)
initn: 3753 init1: 2342 opt: 3697 Z-score: 2278.8 bits: 432.0 E(85289): 3.4e-120
Smith-Waterman score: 3857; 86.9% identity (86.9% similar) in 666 aa overlap (93-718:1-619)
70 80 90 100 110 120
pF1KA0 FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCF
::::::::::::::::::::::::::::::
XP_016 MYGTRCHGCGEFVEGEVVTALGKTYHPNCF
10 20 30
130 140 150 160 170 180
pF1KA0 ACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLAL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 DKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 HYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGS
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 SIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 LGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPEL
280 290 300 310 320 330
430 440
pF1KA0 --------------------------------------GNEPSSGRNSPLPYRPDSRPLT
::::::::::::::::::::::
XP_016 LSPGVQRLSYLRTSSLSPTHSDSRPNPPFRHHFIPHIKGNEPSSGRNSPLPYRPDSRPLT
340 350 360 370 380 390
450 460 470 480 490 500
pF1KA0 PTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETP
:::::::::::::::::::::::::::::
XP_016 PTYAQAPKHFHVPDQGINIYRKPPIYKQH-------------------------------
400 410
510 520 530 540 550 560
pF1KA0 EIETDHWPGPPSFAVIGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEE
::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------------GPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEE
420 430 440 450 460
570 580 590 600 610 620
pF1KA0 MEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVS
470 480 490 500 510 520
630 640 650 660 670 680
pF1KA0 GGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLER
530 540 550 560 570 580
690 700 710
pF1KA0 HLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
::::::::::::::::::::::::::::::::::::
XP_016 HLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
590 600 610
>>XP_005269881 (OMIM: 602330) PREDICTED: actin-binding L (655 aa)
initn: 3271 init1: 3271 opt: 3271 Z-score: 2018.1 bits: 383.8 E(85289): 1.1e-105
Smith-Waterman score: 4502; 93.3% identity (93.3% similar) in 698 aa overlap (21-718:5-655)
10 20 30 40 50 60
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
::::::::::::::::::::::::::::::::::::::::
XP_005 MVKEKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
10 20 30 40
70 80 90 100 110 120
pF1KA0 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKS
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH---------
410 420 430 440 450
490 500 510 520 530 540
pF1KA0 SEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSGREEDDEELLRRR
::::::::::::::::::::::
XP_005 --------------------------------------GPDMKRRSSGREEDDEELLRRR
460 470
550 560 570 580 590 600
pF1KA0 QLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYG
480 490 500 510 520 530
610 620 630 640 650 660
pF1KA0 RNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEM
540 550 560 570 580 590
670 680 690 700 710
pF1KA0 LMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
600 610 620 630 640 650
>>NP_001309815 (OMIM: 602330) actin-binding LIM protein (654 aa)
initn: 3268 init1: 3268 opt: 3268 Z-score: 2016.3 bits: 383.5 E(85289): 1.4e-105
Smith-Waterman score: 4499; 93.1% identity (93.3% similar) in 698 aa overlap (21-718:4-654)
10 20 30 40 50 60
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
.:::::::::::::::::::::::::::::::::::::::
NP_001 MSARVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHI
10 20 30 40
70 80 90 100 110 120
pF1KA0 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRP
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKS
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH---------
410 420 430 440 450
490 500 510 520 530 540
pF1KA0 SEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSGREEDDEELLRRR
::::::::::::::::::::::
NP_001 --------------------------------------GPDMKRRSSGREEDDEELLRRR
460 470
550 560 570 580 590 600
pF1KA0 QLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYG
480 490 500 510 520 530
610 620 630 640 650 660
pF1KA0 RNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEM
540 550 560 570 580 590
670 680 690 700 710
pF1KA0 LMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF
600 610 620 630 640 650
>>XP_016871742 (OMIM: 602330) PREDICTED: actin-binding L (718 aa)
initn: 3265 init1: 3265 opt: 3265 Z-score: 2014.0 bits: 383.2 E(85289): 1.9e-105
Smith-Waterman score: 4496; 93.3% identity (93.3% similar) in 697 aa overlap (22-718:69-718)
10 20 30 40 50
pF1KA0 MLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVL
::::::::::::::::::::::::::::::
XP_016 EPHGWREEEDQDLRRRRGESHRKKKEQPAGVAHPQDPHHPSEKPVIHCHKCGEPCKGEVL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KA0 RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVT
100 110 120 130 140 150
120 130 140 150 160 170
pF1KA0 ALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGR
160 170 180 190 200 210
180 190 200 210 220 230
pF1KA0 DIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQF
220 230 240 250 260 270
240 250 260 270 280 290
pF1KA0 ITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRT
280 290 300 310 320 330
300 310 320 330 340 350
pF1KA0 SSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYT
340 350 360 370 380 390
360 370 380 390 400 410
pF1KA0 SGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTS
400 410 420 430 440 450
420 430 440 450 460 470
pF1KA0 RSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQH
460 470 480 490 500 510
480 490 500 510 520 530
pF1KA0 AALAAQSKSSEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPSFAVIGPDMKRRSSGREE
:::::::::::::
XP_016 -----------------------------------------------GPDMKRRSSGREE
520 530
540 550 560 570 580 590
pF1KA0 DDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSS
540 550 560 570 580 590
600 610 620 630 640 650
pF1KA0 KTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNML
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA0 EPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDM
660 670 680 690 700 710
pF1KA0 KKKAKLF
:::::::
XP_016 KKKAKLF
>>XP_016871736 (OMIM: 602330) PREDICTED: actin-binding L (619 aa)
initn: 3265 init1: 1831 opt: 3227 Z-score: 1991.5 bits: 378.8 E(85289): 3.4e-104
Smith-Waterman score: 3959; 90.1% identity (90.4% similar) in 654 aa overlap (93-718:1-619)
70 80 90 100 110 120
pF1KA0 FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCF
::::::::::::::::::::::::::::::
XP_016 MYGTRCHGCGEFVEGEVVTALGKTYHPNCF
10 20 30
130 140 150 160 170 180
pF1KA0 ACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLAL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 DKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDK
100 110 120 130 140 150
250 260 270 280
pF1KA0 HYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLR---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSK
160 170 180 190 200 210
290 300 310 320 330
pF1KA0 -------------PTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKA
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLIRRTGRSPSLQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKA
220 230 240 250 260 270
340 350 360 370 380 390
pF1KA0 IYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQG
280 290 300 310 320 330
400 410 420 430 440 450
pF1KA0 SINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHV
::::::::::::::::::::::::::
XP_016 SINSPVYSRHSYTPTTSRSPQHFHRP----------------------------------
340 350
460 470 480 490 500 510
pF1KA0 PDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPEIETDHWPGPPS
:::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_016 -DQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPS
360 370 380 390 400 410
520 530 540 550 560 570
pF1KA0 FAVIGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLL
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLL
420 430 440 450 460 470
580 590 600 610 620 630
pF1KA0 ASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDG
480 490 500 510 520 530
640 650 660 670 680 690
pF1KA0 HMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFG
540 550 560 570 580 590
700 710
pF1KA0 MSIQEFDRLPLWRRNDMKKKAKLF
::::::::::::::::::::::::
XP_016 MSIQEFDRLPLWRRNDMKKKAKLF
600 610
718 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:24:10 2016 done: Fri Nov 4 00:24:12 2016
Total Scan time: 12.730 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]