FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0060, 289 aa 1>>>pF1KA0060 289 - 289 aa - 289 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0668+/-0.000382; mu= 16.3618+/- 0.024 mean_var=60.2494+/-12.251, 0's: 0 Z-trim(111.5): 16 B-trim: 133 in 1/52 Lambda= 0.165233 statistics sampled from 20058 (20066) to 20058 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.235), width: 16 Scan time: 5.900 The best scores are: opt bits E(85289) XP_006714810 (OMIM: 601798) PREDICTED: glucosamine ( 289) 1927 467.9 1e-131 NP_005462 (OMIM: 601798) glucosamine-6-phosphate i ( 289) 1927 467.9 1e-131 XP_011535839 (OMIM: 601798) PREDICTED: glucosamine ( 289) 1927 467.9 1e-131 XP_005268405 (OMIM: 601798) PREDICTED: glucosamine ( 318) 1927 467.9 1.1e-131 NP_612208 (OMIM: 613222) glucosamine-6-phosphate i ( 276) 1656 403.3 2.7e-112 NP_001257810 (OMIM: 613222) glucosamine-6-phosphat ( 206) 1264 309.8 2.9e-84 NP_001257809 (OMIM: 613222) glucosamine-6-phosphat ( 242) 1237 303.4 2.8e-82 >>XP_006714810 (OMIM: 601798) PREDICTED: glucosamine-6-p (289 aa) initn: 1927 init1: 1927 opt: 1927 Z-score: 2485.8 bits: 467.9 E(85289): 1e-131 Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289) 10 20 30 40 50 60 pF1KA0 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 190 200 210 220 230 240 250 260 270 280 pF1KA0 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 250 260 270 280 >>NP_005462 (OMIM: 601798) glucosamine-6-phosphate isome (289 aa) initn: 1927 init1: 1927 opt: 1927 Z-score: 2485.8 bits: 467.9 E(85289): 1e-131 Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289) 10 20 30 40 50 60 pF1KA0 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 190 200 210 220 230 240 250 260 270 280 pF1KA0 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD ::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 250 260 270 280 >>XP_011535839 (OMIM: 601798) PREDICTED: glucosamine-6-p (289 aa) initn: 1927 init1: 1927 opt: 1927 Z-score: 2485.8 bits: 467.9 E(85289): 1e-131 Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289) 10 20 30 40 50 60 pF1KA0 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 190 200 210 220 230 240 250 260 270 280 pF1KA0 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 250 260 270 280 >>XP_005268405 (OMIM: 601798) PREDICTED: glucosamine-6-p (318 aa) initn: 1927 init1: 1927 opt: 1927 Z-score: 2485.2 bits: 467.9 E(85289): 1.1e-131 Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:30-318) 10 20 30 pF1KA0 MKLIILEHYSQASEWAAKYIRNRIIQFNPGP ::::::::::::::::::::::::::::::: XP_005 MSSFWSDYLFPFVLWGKLKTQRGSQSKDKMKLIILEHYSQASEWAAKYIRNRIIQFNPGP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 EKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 NFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 SLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 LYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYS 250 260 270 280 290 300 280 pF1KA0 IKEKETEKSQSSKKPYSD :::::::::::::::::: XP_005 IKEKETEKSQSSKKPYSD 310 >>NP_612208 (OMIM: 613222) glucosamine-6-phosphate isome (276 aa) initn: 1658 init1: 1637 opt: 1656 Z-score: 2137.0 bits: 403.3 E(85289): 2.7e-112 Smith-Waterman score: 1656; 88.0% identity (97.4% similar) in 274 aa overlap (1-274:1-274) 10 20 30 40 50 60 pF1KA0 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD :.:.::..:. ::::::::: ::::::.:: ..::::::::::::::::::::::.::: NP_612 MRLVILDNYDLASEWAAKYICNRIIQFKPGQDRYFTLGLPTGSTPLGCYKKLIEYHKNGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA :::::::::::::::::::.:::::::.::::::::::: :.:.:::::::.:::::::: NP_612 LSFKYVKTFNMDEYVGLPRNHPESYHSYMWNNFFKHIDIDPNNAHILDGNAADLQAECDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK ::.::: ::::.::::::::::::::::::::::::::.::::::::::::..:::.:.: NP_612 FENKIKEAGGIDLFVGGIGPDGHIAFNEPGSSLVSRTRLKTLAMDTILANAKYFDGDLSK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_612 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTIFVCD 190 200 210 220 230 240 250 260 270 280 pF1KA0 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD :::::::.::::::::::: :::::::::.:.:. NP_612 EDATLELRVKTVKYFKGLMHVHNKLVDPLFSMKDGN 250 260 270 >>NP_001257810 (OMIM: 613222) glucosamine-6-phosphate is (206 aa) initn: 1285 init1: 1264 opt: 1264 Z-score: 1633.9 bits: 309.8 E(85289): 2.9e-84 Smith-Waterman score: 1264; 90.2% identity (98.5% similar) in 204 aa overlap (71-274:1-204) 50 60 70 80 90 100 pF1KA0 TGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIH :::::::::.:::::::.::::::::::: NP_001 MDEYVGLPRNHPESYHSYMWNNFFKHIDID 10 20 30 110 120 130 140 150 160 pF1KA0 PENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVK :.:.:::::::.::::::::::.::: ::::.::::::::::::::::::::::::::.: NP_001 PNNAHILDGNAADLQAECDAFENKIKEAGGIDLFVGGIGPDGHIAFNEPGSSLVSRTRLK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KA0 TLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGV :::::::::::..:::.:.::::::::::::::::::::::::::::::::::::::::: NP_001 TLAMDTILANAKYFDGDLSKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGV 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA0 NHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKS :::::::::::::::.:::::::::::.::::::::::: :::::::::.:.:. NP_001 NHMWTVSAFQQHPRTIFVCDEDATLELRVKTVKYFKGLMHVHNKLVDPLFSMKDGN 160 170 180 190 200 pF1KA0 QSSKKPYSD >>NP_001257809 (OMIM: 613222) glucosamine-6-phosphate is (242 aa) initn: 1454 init1: 1230 opt: 1237 Z-score: 1598.0 bits: 303.4 E(85289): 2.8e-82 Smith-Waterman score: 1361; 76.3% identity (85.4% similar) in 274 aa overlap (1-274:1-240) 10 20 30 40 50 60 pF1KA0 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD :.:.::..:. ::::::::: ::::::.:: ..::::::::: NP_001 MRLVILDNYDLASEWAAKYICNRIIQFKPGQDRYFTLGLPTG------------------ 10 20 30 40 70 80 90 100 110 120 pF1KA0 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA :::.:::::::.::::::::::: :.:.:::::::.:::::::: NP_001 ----------------LPRNHPESYHSYMWNNFFKHIDIDPNNAHILDGNAADLQAECDA 50 60 70 80 130 140 150 160 170 180 pF1KA0 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK ::.::: ::::.::::::::::::::::::::::::::.::::::::::::..:::.:.: NP_001 FENKIKEAGGIDLFVGGIGPDGHIAFNEPGSSLVSRTRLKTLAMDTILANAKYFDGDLSK 90 100 110 120 130 140 190 200 210 220 230 240 pF1KA0 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_001 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTIFVCD 150 160 170 180 190 200 250 260 270 280 pF1KA0 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD :::::::.::::::::::: :::::::::.:.:. NP_001 EDATLELRVKTVKYFKGLMHVHNKLVDPLFSMKDGN 210 220 230 240 289 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 17:58:23 2016 done: Wed Nov 2 17:58:24 2016 Total Scan time: 5.900 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]