FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0090, 992 aa 1>>>pF1KA0090 992 - 992 aa - 992 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2183+/-0.00112; mu= 16.2210+/- 0.067 mean_var=66.7938+/-13.323, 0's: 0 Z-trim(102.1): 28 B-trim: 0 in 0/47 Lambda= 0.156930 statistics sampled from 6801 (6806) to 6801 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.558), E-opt: 0.2 (0.209), width: 16 Scan time: 3.410 The best scores are: opt bits E(32554) CCDS59191.1 EMC1 gene_id:23065|Hs108|chr1 ( 992) 6507 1482.8 0 CCDS190.1 EMC1 gene_id:23065|Hs108|chr1 ( 993) 6495 1480.1 0 CCDS59190.1 EMC1 gene_id:23065|Hs108|chr1 ( 971) 5854 1335.0 0 >>CCDS59191.1 EMC1 gene_id:23065|Hs108|chr1 (992 aa) initn: 6507 init1: 6507 opt: 6507 Z-score: 7951.7 bits: 1482.8 E(32554): 0 Smith-Waterman score: 6507; 100.0% identity (100.0% similar) in 992 aa overlap (1-992:1-992) 10 20 30 40 50 60 pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 YVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 QGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 VHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYD 910 920 930 940 950 960 970 980 990 pF1KA0 YVLISSVLFGLVFATMITKRLAQVKLLNRAWR :::::::::::::::::::::::::::::::: CCDS59 YVLISSVLFGLVFATMITKRLAQVKLLNRAWR 970 980 990 >>CCDS190.1 EMC1 gene_id:23065|Hs108|chr1 (993 aa) initn: 4231 init1: 4231 opt: 6495 Z-score: 7937.0 bits: 1480.1 E(32554): 0 Smith-Waterman score: 6495; 99.9% identity (99.9% similar) in 993 aa overlap (1-992:1-993) 10 20 30 40 50 60 pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS19 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY 910 920 930 940 950 960 960 970 980 990 pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR ::::::::::::::::::::::::::::::::: CCDS19 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR 970 980 990 >>CCDS59190.1 EMC1 gene_id:23065|Hs108|chr1 (971 aa) initn: 4700 init1: 4231 opt: 5854 Z-score: 7152.9 bits: 1335.0 E(32554): 0 Smith-Waterman score: 6279; 97.6% identity (97.6% similar) in 993 aa overlap (1-992:1-971) 10 20 30 40 50 60 pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE ::::::::::::: :::::::::::::::::::::::: CCDS59 NVIAALNSRTGEIY----------------------VITVSNGGRIMRSWETNIGGLNWE 70 80 90 130 140 150 160 170 180 pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY 220 230 240 250 260 270 310 320 330 340 350 pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS59 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS 280 290 300 310 320 330 360 370 380 390 400 410 pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR 340 350 360 370 380 390 420 430 440 450 460 470 pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL 400 410 420 430 440 450 480 490 500 510 520 530 pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT 460 470 480 490 500 510 540 550 560 570 580 590 pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS 520 530 540 550 560 570 600 610 620 630 640 650 pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR 580 590 600 610 620 630 660 670 680 690 700 710 pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH 640 650 660 670 680 690 720 730 740 750 760 770 pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG 700 710 720 730 740 750 780 790 800 810 820 830 pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF 760 770 780 790 800 810 840 850 860 870 880 890 pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP 820 830 840 850 860 870 900 910 920 930 940 950 pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY 880 890 900 910 920 930 960 970 980 990 pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR ::::::::::::::::::::::::::::::::: CCDS59 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR 940 950 960 970 992 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:00:55 2016 done: Wed Nov 2 18:00:55 2016 Total Scan time: 3.410 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]