FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0092, 474 aa
1>>>pF1KA0092 474 - 474 aa - 474 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6183+/-0.0013; mu= -5.9460+/- 0.077
mean_var=326.7367+/-67.708, 0's: 0 Z-trim(110.1): 43 B-trim: 97 in 2/51
Lambda= 0.070954
statistics sampled from 11368 (11395) to 11368 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.35), width: 16
Scan time: 3.460
The best scores are: opt bits E(32554)
CCDS58166.1 CEP57 gene_id:9702|Hs108|chr11 ( 474) 2983 319.4 5.2e-87
CCDS8304.1 CEP57 gene_id:9702|Hs108|chr11 ( 500) 1699 188.0 2e-47
CCDS58167.1 CEP57 gene_id:9702|Hs108|chr11 ( 491) 1618 179.7 6.2e-45
CCDS5071.1 CEP57L1 gene_id:285753|Hs108|chr6 ( 460) 795 95.4 1.4e-19
CCDS64491.1 CEP57L1 gene_id:285753|Hs108|chr6 ( 391) 777 93.5 4.3e-19
>>CCDS58166.1 CEP57 gene_id:9702|Hs108|chr11 (474 aa)
initn: 2983 init1: 2983 opt: 2983 Z-score: 1675.5 bits: 319.4 E(32554): 5.2e-87
Smith-Waterman score: 2983; 99.8% identity (99.8% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NRLIFEDKATPCVPNARRIKKKKSKPPEKSTSPSHAVVANVQLVLHLMKQHSKALCNDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NRLIFEDKATPCVPNARRIKKKKSKPPEKSTSPSHAVVANVQLVLHLMKQHSKALCNDRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 INSIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 INSIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDE
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 ERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY
::::::::::::::::::::: ::::::::::::::::::::::::::::::::
CCDS58 ERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY
430 440 450 460 470
>>CCDS8304.1 CEP57 gene_id:9702|Hs108|chr11 (500 aa)
initn: 1742 init1: 1699 opt: 1699 Z-score: 964.9 bits: 188.0 E(32554): 2e-47
Smith-Waterman score: 2921; 94.6% identity (94.6% similar) in 500 aa overlap (1-474:1-500)
10 20 30 40 50 60
pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET
190 200 210 220 230 240
250 260 270
pF1KA0 NRLIFEDKATPCVPNARRIKKKKSKPPEK--------------------------STSPS
::::::::::::::::::::::::::::: :::::
CCDS83 NRLIFEDKATPCVPNARRIKKKKSKPPEKKSSRNYFGAQPHYRLCLGDMPFVAGKSTSPS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQL
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
CCDS83 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQL
430 440 450 460 470 480
460 470
pF1KA0 LKDMQSIQNSLQSSSLCWDY
::::::::::::::::::::
CCDS83 LKDMQSIQNSLQSSSLCWDY
490 500
>>CCDS58167.1 CEP57 gene_id:9702|Hs108|chr11 (491 aa)
initn: 1657 init1: 1614 opt: 1618 Z-score: 920.2 bits: 179.7 E(32554): 6.2e-45
Smith-Waterman score: 2840; 93.7% identity (94.5% similar) in 489 aa overlap (12-474:3-491)
10 20 30 40 50 60
pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA
....:::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MLTRIDNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET
180 190 200 210 220 230
250 260 270
pF1KA0 NRLIFEDKATPCVPNARRIKKKKSKPPEK--------------------------STSPS
::::::::::::::::::::::::::::: :::::
CCDS58 NRLIFEDKATPCVPNARRIKKKKSKPPEKKSSRNYFGAQPHYRLCLGDMPFVAGKSTSPS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KA0 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL
300 310 320 330 340 350
340 350 360 370 380 390
pF1KA0 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK
360 370 380 390 400 410
400 410 420 430 440 450
pF1KA0 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQL
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
CCDS58 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQL
420 430 440 450 460 470
460 470
pF1KA0 LKDMQSIQNSLQSSSLCWDY
::::::::::::::::::::
CCDS58 LKDMQSIQNSLQSSSLCWDY
480 490
>>CCDS5071.1 CEP57L1 gene_id:285753|Hs108|chr6 (460 aa)
initn: 773 init1: 571 opt: 795 Z-score: 465.3 bits: 95.4 E(32554): 1.4e-19
Smith-Waterman score: 796; 32.9% identity (69.0% similar) in 465 aa overlap (27-473:3-459)
10 20 30 40 50
pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSK---P
: . :: : .. :. : . ::. :
CCDS50 MDSELMHSIVGSYHKPPERVFVPSFTQNEPSQNCHP
10 20 30
60 70 80 90 100 110
pF1KA0 T---LAYPE----SNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDE
. .. :. ::.:.. :::.::.::.:::::: :::.... ::::. .:::.:..
CCDS50 ANLEVTSPKILHSPNSQALILALKTLQEKIHRLELERTQAEDNLNILSREAAQYKKALEN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KA0 QIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVS
. .::. ...: :...... :: .:...:.:::::::: . :. ..: :.. .::.:..
CCDS50 ETNERNLAHQELIKQKKDISIQLSSAQSRCTLLEKQLEYTKRMVLNVEREKNMILEQQAQ
100 110 120 130 140 150
180 190 200 210 220 230
pF1KA0 LERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAK
:.::...:: .. ..:::::.::.: .::: : :: :...:: ::.:::..:: .: :
CCDS50 LQREKEQDQMKLYAKLEKLDVLEKECFRLTTTQKTAEDKIKHLEEKLKEEEHQRKLFQDK
160 170 180 190 200 210
240 250 260 270 280
pF1KA0 AAELQTGLETNRLIFEDKATPCVPNARRIKKKKSK-----PPEKSTSPSHAVVANVQLVL
:.::::::: ...:. . .. . .. ..::.: :: . : :. .:
CCDS50 ASELQTGLEISKIIMSSVSNLKHSKEKKKSSKKTKCIKRRPPWQICSKFGAL----PFVA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KA0 HLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSN---GINEELSEVLQTLQ
. :.:: .. .: . .. . . . .. .. ::.:. .: ..:::.:...:
CCDS50 EKMRQHRDPHILQKPFN-VTETRCLPKPSRTTSWCKAIPPDSEKSISICDNLSELLMAMQ
280 290 300 310 320 330
350 360 370 380 390 400
pF1KA0 DEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQ
::. :::..::.: : ..:. . . : .::::: :. .:: :..::.:..:.: .. :
CCDS50 DELDQMSMEHQELLKQMKETESHSVCDDIECELECLLKKMEIKGEQISKLKKHQDSVCKL
340 350 360 370 380 390
410 420 430 440 450 460
pF1KA0 KLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQLLKDMQSIQ
. . :..... .. .:. .. ..: .. : . . .. .... .. ....:
CCDS50 QQKVQNSKMSEASGIQQEDSYPKGSKNIKNSPRK--CLTDTNLFQKNSSFHPIR-VHNLQ
400 410 420 430 440
470
pF1KA0 NSLQSSSLCWDY
.:. ... :.
CCDS50 MKLRRDDIMWEQ
450 460
>>CCDS64491.1 CEP57L1 gene_id:285753|Hs108|chr6 (391 aa)
initn: 766 init1: 571 opt: 777 Z-score: 456.3 bits: 93.5 E(32554): 4.3e-19
Smith-Waterman score: 778; 36.9% identity (70.7% similar) in 393 aa overlap (27-401:3-390)
10 20 30 40 50
pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSK---P
: . :: : .. :. : . ::. :
CCDS64 MDSELMHSIVGSYHKPPERVFVPSFTQNEPSQNCHP
10 20 30
60 70 80 90 100 110
pF1KA0 T---LAYPE----SNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDE
. .. :. ::.:.. :::.::.::.:::::: :::.... ::::. .:::.:..
CCDS64 ANLEVTSPKILHSPNSQALILALKTLQEKIHRLELERTQAEDNLNILSREAAQYKKALEN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KA0 QIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVS
. .::. ...: :...... :: .:...:.:::::::: . :. ..: :.. .::.:..
CCDS64 ETNERNLAHQELIKQKKDISIQLSSAQSRCTLLEKQLEYTKRMVLNVEREKNMILEQQAQ
100 110 120 130 140 150
180 190 200 210 220 230
pF1KA0 LERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAK
:.::...:: .. ..:::::.::.: .::: : :: :...:: ::.:::..:: .: :
CCDS64 LQREKEQDQMKLYAKLEKLDVLEKECFRLTTTQKTAEDKIKHLEEKLKEEEHQRKLFQDK
160 170 180 190 200 210
240 250 260 270 280
pF1KA0 AAELQTGLETNRLIFEDKATPCVPNARRIKKKKSK-----PPEKSTSPSHAVVANVQLVL
:.::::::: ...:. . .. . .. ..::.: :: . : :. .:
CCDS64 ASELQTGLEISKIIMSSVSNLKHSKEKKKSSKKTKCIKRRPPWQICSKFGAL----PFVA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KA0 HLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSN---GINEELSEVLQTLQ
. :.:: .. .: . .. . . . .. .. ::.:. .: ..:::.:...:
CCDS64 EKMRQHRDPHILQKPFN-VTETRCLPKPSRTTSWCKAIPPDSEKSISICDNLSELLMAMQ
280 290 300 310 320 330
350 360 370 380 390 400
pF1KA0 DEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQ
::. :::..::.: : ..:. . . : .::::: :. .:: :..::.:..:.: ....
CCDS64 DELDQMSMEHQELLKQMKETESHSVCDDIECELECLLKKMEIKGEQISKLKKHQDSVRRL
340 350 360 370 380 390
410 420 430 440 450 460
pF1KA0 KLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQLLKDMQSIQ
474 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:01:39 2016 done: Wed Nov 2 18:01:39 2016
Total Scan time: 3.460 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]