FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0092, 474 aa 1>>>pF1KA0092 474 - 474 aa - 474 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.6183+/-0.0013; mu= -5.9460+/- 0.077 mean_var=326.7367+/-67.708, 0's: 0 Z-trim(110.1): 43 B-trim: 97 in 2/51 Lambda= 0.070954 statistics sampled from 11368 (11395) to 11368 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.35), width: 16 Scan time: 3.460 The best scores are: opt bits E(32554) CCDS58166.1 CEP57 gene_id:9702|Hs108|chr11 ( 474) 2983 319.4 5.2e-87 CCDS8304.1 CEP57 gene_id:9702|Hs108|chr11 ( 500) 1699 188.0 2e-47 CCDS58167.1 CEP57 gene_id:9702|Hs108|chr11 ( 491) 1618 179.7 6.2e-45 CCDS5071.1 CEP57L1 gene_id:285753|Hs108|chr6 ( 460) 795 95.4 1.4e-19 CCDS64491.1 CEP57L1 gene_id:285753|Hs108|chr6 ( 391) 777 93.5 4.3e-19 >>CCDS58166.1 CEP57 gene_id:9702|Hs108|chr11 (474 aa) initn: 2983 init1: 2983 opt: 2983 Z-score: 1675.5 bits: 319.4 E(32554): 5.2e-87 Smith-Waterman score: 2983; 99.8% identity (99.8% similar) in 474 aa overlap (1-474:1-474) 10 20 30 40 50 60 pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 NRLIFEDKATPCVPNARRIKKKKSKPPEKSTSPSHAVVANVQLVLHLMKQHSKALCNDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NRLIFEDKATPCVPNARRIKKKKSKPPEKSTSPSHAVVANVQLVLHLMKQHSKALCNDRV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INSIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 INSIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDE 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 ERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY ::::::::::::::::::::: :::::::::::::::::::::::::::::::: CCDS58 ERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY 430 440 450 460 470 >>CCDS8304.1 CEP57 gene_id:9702|Hs108|chr11 (500 aa) initn: 1742 init1: 1699 opt: 1699 Z-score: 964.9 bits: 188.0 E(32554): 2e-47 Smith-Waterman score: 2921; 94.6% identity (94.6% similar) in 500 aa overlap (1-474:1-500) 10 20 30 40 50 60 pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET 190 200 210 220 230 240 250 260 270 pF1KA0 NRLIFEDKATPCVPNARRIKKKKSKPPEK--------------------------STSPS ::::::::::::::::::::::::::::: ::::: CCDS83 NRLIFEDKATPCVPNARRIKKKKSKPPEKKSSRNYFGAQPHYRLCLGDMPFVAGKSTSPS 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS83 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA0 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQL ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS83 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQL 430 440 450 460 470 480 460 470 pF1KA0 LKDMQSIQNSLQSSSLCWDY :::::::::::::::::::: CCDS83 LKDMQSIQNSLQSSSLCWDY 490 500 >>CCDS58167.1 CEP57 gene_id:9702|Hs108|chr11 (491 aa) initn: 1657 init1: 1614 opt: 1618 Z-score: 920.2 bits: 179.7 E(32554): 6.2e-45 Smith-Waterman score: 2840; 93.7% identity (94.5% similar) in 489 aa overlap (12-474:3-491) 10 20 30 40 50 60 pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA ....::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MLTRIDNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSKPTLA 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQERENSKN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQT 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLET 180 190 200 210 220 230 250 260 270 pF1KA0 NRLIFEDKATPCVPNARRIKKKKSKPPEK--------------------------STSPS ::::::::::::::::::::::::::::: ::::: CCDS58 NRLIFEDKATPCVPNARRIKKKKSKPPEKKSSRNYFGAQPHYRLCLGDMPFVAGKSTSPS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KA0 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HAVVANVQLVLHLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSNGINEEL 300 310 320 330 340 350 340 350 360 370 380 390 pF1KA0 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SEVLQTLQDEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRK 360 370 380 390 400 410 400 410 420 430 440 450 pF1KA0 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQL ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS58 YQAQLEKQKLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKLRPGEKRRKNLQL 420 430 440 450 460 470 460 470 pF1KA0 LKDMQSIQNSLQSSSLCWDY :::::::::::::::::::: CCDS58 LKDMQSIQNSLQSSSLCWDY 480 490 >>CCDS5071.1 CEP57L1 gene_id:285753|Hs108|chr6 (460 aa) initn: 773 init1: 571 opt: 795 Z-score: 465.3 bits: 95.4 E(32554): 1.4e-19 Smith-Waterman score: 796; 32.9% identity (69.0% similar) in 465 aa overlap (27-473:3-459) 10 20 30 40 50 pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSK---P : . :: : .. :. : . ::. : CCDS50 MDSELMHSIVGSYHKPPERVFVPSFTQNEPSQNCHP 10 20 30 60 70 80 90 100 110 pF1KA0 T---LAYPE----SNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDE . .. :. ::.:.. :::.::.::.:::::: :::.... ::::. .:::.:.. CCDS50 ANLEVTSPKILHSPNSQALILALKTLQEKIHRLELERTQAEDNLNILSREAAQYKKALEN 40 50 60 70 80 90 120 130 140 150 160 170 pF1KA0 QIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVS . .::. ...: :...... :: .:...:.:::::::: . :. ..: :.. .::.:.. CCDS50 ETNERNLAHQELIKQKKDISIQLSSAQSRCTLLEKQLEYTKRMVLNVEREKNMILEQQAQ 100 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 LERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAK :.::...:: .. ..:::::.::.: .::: : :: :...:: ::.:::..:: .: : CCDS50 LQREKEQDQMKLYAKLEKLDVLEKECFRLTTTQKTAEDKIKHLEEKLKEEEHQRKLFQDK 160 170 180 190 200 210 240 250 260 270 280 pF1KA0 AAELQTGLETNRLIFEDKATPCVPNARRIKKKKSK-----PPEKSTSPSHAVVANVQLVL :.::::::: ...:. . .. . .. ..::.: :: . : :. .: CCDS50 ASELQTGLEISKIIMSSVSNLKHSKEKKKSSKKTKCIKRRPPWQICSKFGAL----PFVA 220 230 240 250 260 270 290 300 310 320 330 340 pF1KA0 HLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSN---GINEELSEVLQTLQ . :.:: .. .: . .. . . . .. .. ::.:. .: ..:::.:...: CCDS50 EKMRQHRDPHILQKPFN-VTETRCLPKPSRTTSWCKAIPPDSEKSISICDNLSELLMAMQ 280 290 300 310 320 330 350 360 370 380 390 400 pF1KA0 DEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQ ::. :::..::.: : ..:. . . : .::::: :. .:: :..::.:..:.: .. : CCDS50 DELDQMSMEHQELLKQMKETESHSVCDDIECELECLLKKMEIKGEQISKLKKHQDSVCKL 340 350 360 370 380 390 410 420 430 440 450 460 pF1KA0 KLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQLLKDMQSIQ . . :..... .. .:. .. ..: .. : . . .. .... .. ....: CCDS50 QQKVQNSKMSEASGIQQEDSYPKGSKNIKNSPRK--CLTDTNLFQKNSSFHPIR-VHNLQ 400 410 420 430 440 470 pF1KA0 NSLQSSSLCWDY .:. ... :. CCDS50 MKLRRDDIMWEQ 450 460 >>CCDS64491.1 CEP57L1 gene_id:285753|Hs108|chr6 (391 aa) initn: 766 init1: 571 opt: 777 Z-score: 456.3 bits: 93.5 E(32554): 4.3e-19 Smith-Waterman score: 778; 36.9% identity (70.7% similar) in 393 aa overlap (27-401:3-390) 10 20 30 40 50 pF1KA0 MAAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPFLNSDLRRSPSK---P : . :: : .. :. : . ::. : CCDS64 MDSELMHSIVGSYHKPPERVFVPSFTQNEPSQNCHP 10 20 30 60 70 80 90 100 110 pF1KA0 T---LAYPE----SNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDE . .. :. ::.:.. :::.::.::.:::::: :::.... ::::. .:::.:.. CCDS64 ANLEVTSPKILHSPNSQALILALKTLQEKIHRLELERTQAEDNLNILSREAAQYKKALEN 40 50 60 70 80 90 120 130 140 150 160 170 pF1KA0 QIQERENSKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVS . .::. ...: :...... :: .:...:.:::::::: . :. ..: :.. .::.:.. CCDS64 ETNERNLAHQELIKQKKDISIQLSSAQSRCTLLEKQLEYTKRMVLNVEREKNMILEQQAQ 100 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 LERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAK :.::...:: .. ..:::::.::.: .::: : :: :...:: ::.:::..:: .: : CCDS64 LQREKEQDQMKLYAKLEKLDVLEKECFRLTTTQKTAEDKIKHLEEKLKEEEHQRKLFQDK 160 170 180 190 200 210 240 250 260 270 280 pF1KA0 AAELQTGLETNRLIFEDKATPCVPNARRIKKKKSK-----PPEKSTSPSHAVVANVQLVL :.::::::: ...:. . .. . .. ..::.: :: . : :. .: CCDS64 ASELQTGLEISKIIMSSVSNLKHSKEKKKSSKKTKCIKRRPPWQICSKFGAL----PFVA 220 230 240 250 260 270 290 300 310 320 330 340 pF1KA0 HLMKQHSKALCNDRVINSIPLAKQVSSRGGKSKKLSVTPPSSN---GINEELSEVLQTLQ . :.:: .. .: . .. . . . .. .. ::.:. .: ..:::.:...: CCDS64 EKMRQHRDPHILQKPFN-VTETRCLPKPSRTTSWCKAIPPDSEKSISICDNLSELLMAMQ 280 290 300 310 320 330 350 360 370 380 390 400 pF1KA0 DEFGQMSFDHQQLAKLIQESPTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQ ::. :::..::.: : ..:. . . : .::::: :. .:: :..::.:..:.: .... CCDS64 DELDQMSMEHQELLKQMKETESHSVCDDIECELECLLKKMEIKGEQISKLKKHQDSVRRL 340 350 360 370 380 390 410 420 430 440 450 460 pF1KA0 KLEKQKKELKATKKTLDEERNSSSRSGITGTTNKKDFMKQRPGEKRRKNLQLLKDMQSIQ 474 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:01:39 2016 done: Wed Nov 2 18:01:39 2016 Total Scan time: 3.460 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]