FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0099, 1162 aa 1>>>pF1KA0099 1162 - 1162 aa - 1162 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9900+/-0.00107; mu= 0.9212+/- 0.064 mean_var=222.3012+/-45.044, 0's: 0 Z-trim(111.5): 45 B-trim: 0 in 0/51 Lambda= 0.086021 statistics sampled from 12412 (12435) to 12412 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.382), width: 16 Scan time: 5.900 The best scores are: opt bits E(32554) CCDS338.1 PUM1 gene_id:9698|Hs108|chr1 (1186) 4043 515.5 3e-145 CCDS44099.1 PUM1 gene_id:9698|Hs108|chr1 (1188) 3868 493.8 1e-138 CCDS74487.1 PUM2 gene_id:23369|Hs108|chr2 (1008) 3277 420.4 1.1e-116 CCDS1698.1 PUM2 gene_id:23369|Hs108|chr2 (1064) 3277 420.4 1.1e-116 CCDS74486.1 PUM2 gene_id:23369|Hs108|chr2 ( 929) 2502 324.2 9.1e-88 >>CCDS338.1 PUM1 gene_id:9698|Hs108|chr1 (1186 aa) initn: 6598 init1: 2904 opt: 4043 Z-score: 2721.1 bits: 515.5 E(32554): 3e-145 Smith-Waterman score: 7664; 97.4% identity (97.4% similar) in 1189 aa overlap (1-1162:1-1186) 10 20 30 40 50 60 pF1KA0 MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 HSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 HSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 GPRDADSDENDKGEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GPRDADSDENDKGEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 DYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIAGL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: CCDS33 DYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHI-GL 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 APAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 APAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAA 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 AAAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AAAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAF 480 490 500 510 520 530 550 560 570 580 590 pF1KA0 GQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQA--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVA 540 550 560 570 580 590 600 610 620 630 pF1KA0 ------------------------GTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSS :::::::::::::::::::::::::::::::::::: CCDS33 AAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSS 600 610 620 630 640 650 640 650 660 670 680 690 pF1KA0 LFSQGSAQPANTSLGFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LFSQGSAQPANTSLGFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKR 660 670 680 690 700 710 700 710 720 730 740 750 pF1KA0 TSSSLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TSSSLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTN 720 730 740 750 760 770 760 770 780 790 800 810 pF1KA0 GSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNN 780 790 800 810 820 830 820 830 840 850 860 870 pF1KA0 RYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLNVDVFGN ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS33 RYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGN 840 850 860 870 880 890 880 890 900 910 920 930 pF1KA0 YVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVREL ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS33 YVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQ--NEMVREL 900 910 920 930 940 950 940 950 960 970 980 990 pF1KA0 DGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHC 960 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KA0 LPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KA0 ASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQR 1080 1090 1100 1110 1120 1130 1120 1130 1140 1150 1160 pF1KA0 KIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII 1140 1150 1160 1170 1180 >>CCDS44099.1 PUM1 gene_id:9698|Hs108|chr1 (1188 aa) initn: 6622 init1: 3732 opt: 3868 Z-score: 2603.7 bits: 493.8 E(32554): 1e-138 Smith-Waterman score: 7688; 97.6% identity (97.6% similar) in 1189 aa overlap (1-1162:1-1188) 10 20 30 40 50 60 pF1KA0 MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 HSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGGF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 GPRDADSDENDKGEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GPRDADSDENDKGEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 DYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIAGL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: CCDS44 DYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHI-GL 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 APAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 APAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAA 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 AAAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 AAAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAF 480 490 500 510 520 530 550 560 570 580 590 pF1KA0 GQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQA--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVA 540 550 560 570 580 590 600 610 620 630 pF1KA0 ------------------------GTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSS :::::::::::::::::::::::::::::::::::: CCDS44 AAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSS 600 610 620 630 640 650 640 650 660 670 680 690 pF1KA0 LFSQGSAQPANTSLGFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LFSQGSAQPANTSLGFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKR 660 670 680 690 700 710 700 710 720 730 740 750 pF1KA0 TSSSLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TSSSLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTN 720 730 740 750 760 770 760 770 780 790 800 810 pF1KA0 GSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNN 780 790 800 810 820 830 820 830 840 850 860 870 pF1KA0 RYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLNVDVFGN ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS44 RYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGN 840 850 860 870 880 890 880 890 900 910 920 930 pF1KA0 YVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVREL 900 910 920 930 940 950 940 950 960 970 980 990 pF1KA0 DGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHC 960 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KA0 LPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KA0 ASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQR 1080 1090 1100 1110 1120 1130 1120 1130 1140 1150 1160 pF1KA0 KIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII 1140 1150 1160 1170 1180 >>CCDS74487.1 PUM2 gene_id:23369|Hs108|chr2 (1008 aa) initn: 4730 init1: 1696 opt: 3277 Z-score: 2208.4 bits: 420.4 E(32554): 1.1e-116 Smith-Waterman score: 4985; 76.8% identity (89.1% similar) in 1016 aa overlap (184-1162:1-1008) 160 170 180 190 200 210 pF1KA0 ETDESSKDGPKGIFLGDQWRDSAWGTSDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSE .::::::::: ::.:: :::::..:::::: CCDS74 MSQPIMVQRRSGQGFHGNSEVNAILSPRSE 10 20 30 220 230 240 250 260 pF1KA0 SGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDKGEKKNKGT-FDGDKLGDL :::::::::::::::::.: : .:::.:: :::..: .::..:.:.. :. :. :: CCDS74 SGGLGVSMVEYVLSSSPADKLDSRFRKGNFGTRDAETDGPEKGDQKGKASPFEEDQNRDL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KA0 KEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEV-DLLGPNQNGSEGLAQLTST :. : .: :: . ::.::: :::.::::. : : .:: . :::: : ::::. : . CCDS74 KQGDDDDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPNTNPSEGLGPLPNP 100 110 120 130 140 150 330 340 350 360 370 380 pF1KA0 NGAKP-VEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVGLFDYNSQQQL .. :: ::.::: :.:. :: ::.::.: ::::: :.:::.::..:::::::::::::: CCDS74 TANKPLVEEFSNPETQN--LDAMEQVGLESLQFDYPGNQVPMDSSGATVGLFDYNSQQQL 160 170 180 190 200 390 400 410 420 430 440 pF1KA0 FQRPNALAVQQLTAAQQQQYALAAAHQPHIAG-----LAPAAFVPNPYIISAAPPGTDPY ::: :::.:::::::::::::::::.:::::: ::::::::::::::::::::::: CCDS74 FQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPY 210 220 230 240 250 260 450 460 470 480 490 500 pF1KA0 TA-GLAAAATL-GPAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSANQQTTPQAQQG :: :::::::: :::::: ::::: :::::::.::::::::: :.:.:.::.. ::: : CCDS74 TAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQAAAA--ANNTASQQAASQAQPG 270 280 290 300 310 320 510 520 530 540 550 560 pF1KA0 QQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYY ::::::.::.::::::::.:::::.. :.::::.: .::::::::.::::: ::::.::: CCDS74 QQQVLRAGAGQRPLTPNQGQQGQQAESLAAAAAANPTLAFGQGLATGMPGYQVLAPTAYY 330 340 350 360 370 380 570 580 590 pF1KA0 DQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQA----------------------- ::::::::. :::.::::::::.::.::.:::.:::: CCDS74 DQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTASSLTGSTNGLFRP 390 400 410 420 430 440 600 610 620 630 640 650 pF1KA0 -GTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSSLFSQGSAQPANTSLGFGSSSSLG ::: :: : ::::..:: :.::::..::...::::::::.: .::..:::::::..::: CCDS74 IGTQPPQ-QQQQQPSTNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSTSLGFGSGNSLG 450 460 470 480 490 500 660 670 680 690 700 710 pF1KA0 ATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLTPIGHSFYNGLSFSSSPG :..::::.:::..:..: ..:..::.::. :::::::.::::.:::. :::.:.:::::. CCDS74 AAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPS 510 520 530 540 550 560 720 730 740 750 760 770 pF1KA0 PVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSAS :.::::::: :::: :::::::::::::::.:::::::::::::::::::::::::::.: CCDS74 PIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTS 570 580 590 600 610 620 780 790 800 810 820 830 pF1KA0 SLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHG :::: :: :: :::::. ::.::::::::::::::::.::::::.. :::.:::::::: CCDS74 SLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHG 630 640 650 660 670 680 840 850 860 870 880 890 pF1KA0 SRFIQLKLERATPAERQLVFNEILQAAYQLNVDVFGNYVIQKFFEFGSLEQKLALAERIR ::::: :::::::::::.:::::::::::: .:::::::::::::::::.:::::: ::: CCDS74 SRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIR 690 700 710 720 730 740 900 910 920 930 940 950 pF1KA0 GHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIEC :::: :::::::::::::::: : :::: .:::.::::::::::::::::::::::::: CCDS74 GHVLPLALQMYGCRVIQKALESISSDQQ--SEMVKELDGHVLKCVKDQNGNHVVQKCIEC 750 760 770 780 790 800 960 970 980 990 1000 1010 pF1KA0 VQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQ ::::::::::::::::::.:::::::::::::::::: .:::::::::::::::::::: CCDS74 VQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQ 810 820 830 840 850 860 1020 1030 1040 1050 1060 1070 pF1KA0 YGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDE ::::::::::::::::::::::.::::.::.::::::::::::::::::::.:::.:::: CCDS74 YGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDE 870 880 890 900 910 920 1080 1090 1100 1110 1120 1130 pF1KA0 VCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHI :: .::::::::::::::::::::::::::.:::.::::.::::::::.::::::::::: CCDS74 VCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHI 930 940 950 960 970 980 1140 1150 1160 pF1KA0 LAKLEKYYMKNGVDLGPICGPPNGII ::::::::.::. ::::: :::::.. CCDS74 LAKLEKYYLKNSPDLGPIGGPPNGML 990 1000 >>CCDS1698.1 PUM2 gene_id:23369|Hs108|chr2 (1064 aa) initn: 4898 init1: 1696 opt: 3277 Z-score: 2208.1 bits: 420.4 E(32554): 1.1e-116 Smith-Waterman score: 5277; 76.6% identity (89.1% similar) in 1073 aa overlap (128-1162:1-1064) 100 110 120 130 140 150 pF1KA0 SGGGGYNNSKHRWPTGDNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDE .::::::::::.:.::: ::: ::::: :. CCDS16 MNHDFQALALESRGMGE-LLPTKKFWEPDD 10 20 160 170 180 190 200 210 pF1KA0 SSKDGPKGIFLGD-QWRDSAWGTSDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGG :.::: ::::::: .::..:::.: ::.::::::::: ::.:: :::::..::::::::: CCDS16 STKDGQKGIFLGDDEWRETAWGASHHSMSQPIMVQRRSGQGFHGNSEVNAILSPRSESGG 30 40 50 60 70 80 220 230 240 250 260 270 pF1KA0 LGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDKGEKKNKGT-FDGDKLGDLKEE ::::::::::::::.: : .:::.:: :::..: .::..:.:.. :. :. :::. CCDS16 LGVSMVEYVLSSSPADKLDSRFRKGNFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQG 90 100 110 120 130 140 280 290 300 310 320 330 pF1KA0 GDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEV-DLLGPNQNGSEGLAQLTSTNGA : .: :: . ::.::: :::.::::. : : .:: . :::: : ::::. : . .. CCDS16 DDDDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPNTNPSEGLGPLPNPTAN 150 160 170 180 190 200 340 350 360 370 380 390 pF1KA0 KP-VEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVGLFDYNSQQQLFQR :: ::.::: :.:. :: ::.::.: ::::: :.:::.::..::::::::::::::::: CCDS16 KPLVEEFSNPETQN--LDAMEQVGLESLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQR 210 220 230 240 250 260 400 410 420 430 440 pF1KA0 PNALAVQQLTAAQQQQYALAAAHQPHIAG-----LAPAAFVPNPYIISAAPPGTDPYTA- :::.:::::::::::::::::.:::::: ::::::::::::::::::::::::: CCDS16 TNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAA 270 280 290 300 310 320 450 460 470 480 490 500 pF1KA0 GLAAAATL-GPAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSANQQTTPQAQQGQQQ :::::::: :::::: ::::: :::::::.:::::::::: .:.:.::.. ::: :::: CCDS16 GLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQAAAAA--NNTASQQAASQAQPGQQQ 330 340 350 360 370 380 510 520 530 540 550 560 pF1KA0 VLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYDQT :::.::.::::::::.:::::.. :.::::.: .::::::::.::::: ::::.:::::: CCDS16 VLRAGAGQRPLTPNQGQQGQQAESLAAAAAANPTLAFGQGLATGMPGYQVLAPTAYYDQT 390 400 410 420 430 440 570 580 590 pF1KA0 GALVVNAGARNGLGAPVRLVAPAPVIISSSAAQA------------------------GT :::::. :::.::::::::.::.::.:::.:::: :: CCDS16 GALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTASSLTGSTNGLFRPIGT 450 460 470 480 490 500 600 610 620 630 640 650 pF1KA0 QQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSSLFSQGSAQPANTSLGFGSSSSLGATL : :: : ::::..:: :.::::..::...::::::::.: .::..:::::::..::::.. CCDS16 QPPQQQ-QQQPSTNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSTSLGFGSGNSLGAAI 510 520 530 540 550 560 660 670 680 690 700 710 pF1KA0 GSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLTPIGHSFYNGLSFSSSPGPVG ::::.:::..:..: ..:..::.::. :::::::.::::.:::. :::.:.:::::.:.: CCDS16 GSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIG 570 580 590 600 610 620 720 730 740 750 760 770 pF1KA0 MPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLF :::::: :::: :::::::::::::::.:::::::::::::::::::::::::::.:::: CCDS16 MPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLF 630 640 650 660 670 680 780 790 800 810 820 830 pF1KA0 SPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRF : :: :: :::::. ::.::::::::::::::::.::::::.. :::.::::::::::: CCDS16 SSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRF 690 700 710 720 730 740 840 850 860 870 880 890 pF1KA0 IQLKLERATPAERQLVFNEILQAAYQLNVDVFGNYVIQKFFEFGSLEQKLALAERIRGHV :: :::::::::::.:::::::::::: .:::::::::::::::::.:::::: :::::: CCDS16 IQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHV 750 760 770 780 790 800 900 910 920 930 940 950 pF1KA0 LSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQP : :::::::::::::::: : :::: .:::.:::::::::::::::::::::::::::: CCDS16 LPLALQMYGCRVIQKALESISSDQQ--SEMVKELDGHVLKCVKDQNGNHVVQKCIECVQP 810 820 830 840 850 860 960 970 980 990 1000 1010 pF1KA0 QSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGN :::::::::::::::.:::::::::::::::::: .::::::::::::::::::::::: CCDS16 QSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGN 870 880 890 900 910 920 1020 1030 1040 1050 1060 1070 pF1KA0 YVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCT :::::::::::::::::::.::::.::.::::::::::::::::::::.:::.:::::: CCDS16 YVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCC 930 940 950 960 970 980 1080 1090 1100 1110 1120 1130 pF1KA0 MNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAK .::::::::::::::::::::::::::.:::.::::.::::::::.:::::::::::::: CCDS16 QNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAK 990 1000 1010 1020 1030 1040 1140 1150 1160 pF1KA0 LEKYYMKNGVDLGPICGPPNGII :::::.::. ::::: :::::.. CCDS16 LEKYYLKNSPDLGPIGGPPNGML 1050 1060 >>CCDS74486.1 PUM2 gene_id:23369|Hs108|chr2 (929 aa) initn: 4032 init1: 1469 opt: 2502 Z-score: 1689.2 bits: 324.2 E(32554): 9.1e-88 Smith-Waterman score: 4423; 71.1% identity (81.8% similar) in 1016 aa overlap (184-1162:1-929) 160 170 180 190 200 210 pF1KA0 ETDESSKDGPKGIFLGDQWRDSAWGTSDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSE .::::::::: ::.:: :::::..:::::: CCDS74 MSQPIMVQRRSGQGFHGNSEVNAILSPRSE 10 20 30 220 230 240 250 260 pF1KA0 SGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDKGEKKNKGT-FDGDKLGDL :::::::::::::::::.: : .:::.:: :::..: .::..:.:.. :. :. :: CCDS74 SGGLGVSMVEYVLSSSPADKLDSRFRKGNFGTRDAETDGPEKGDQKGKASPFEEDQNRDL 40 50 60 70 80 90 270 280 290 300 310 320 pF1KA0 KEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEV-DLLGPNQNGSEGLAQLTST :. : .: :: . ::.::: :::.::::. : : .:: . :::: : ::::. : . CCDS74 KQGDDDDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPNTNPSEGLGPLPNP 100 110 120 130 140 150 330 340 350 360 370 380 pF1KA0 NGAKP-VEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVGLFDYNSQQQL .. :: ::.::: :.:. :: ::.::.: ::::: :.:::.::..:::::::::::::: CCDS74 TANKPLVEEFSNPETQN--LDAMEQVGLESLQFDYPGNQVPMDSSGATVGLFDYNSQQQL 160 170 180 190 200 390 400 410 420 430 440 pF1KA0 FQRPNALAVQQLTAAQQQQYALAAAHQPHIAG-----LAPAAFVPNPYIISAAPPGTDPY ::: :::.:::::::::::::::::.:::::: ::::::::::::::::::::::: CCDS74 FQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPY 210 220 230 240 250 260 450 460 470 480 490 500 pF1KA0 TA-GLAAAATL-GPAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSANQQTTPQAQQG :: :::::::: :::::: ::::: :::::::.::::::::: :.:.:.::.. ::: : CCDS74 TAAGLAAAATLAGPAVVPPQYYGV-PWGVYPANLFQQQAAAA--ANNTASQQAASQAQPG 270 280 290 300 310 320 510 520 530 540 550 560 pF1KA0 QQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYY ::::::.::.::::::::.:::::.. :.::::.: .::::::::.::::: ::::.::: CCDS74 QQQVLRAGAGQRPLTPNQGQQGQQAESLAAAAAANPTLAFGQGLATGMPGYQVLAPTAYY 330 340 350 360 370 380 570 580 590 pF1KA0 DQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQA----------------------- ::::::::. :::.::::::::.::.::.:::.:::: CCDS74 DQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTASSLTGSTNGLFRP 390 400 410 420 430 440 600 610 620 630 640 650 pF1KA0 -GTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSSLFSQGSAQPANTSLGFGSSSSLG ::: :: : ::::..:: :.::::..::...::::::::.: .::..:::::::..::: CCDS74 IGTQPPQ-QQQQQPSTNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSTSLGFGSGNSLG 450 460 470 480 490 500 660 670 680 690 700 710 pF1KA0 ATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLTPIGHSFYNGLSFSSSPG :..::::.:::.. CCDS74 AAIGSALSGFGSS----------------------------------------------- 510 720 730 740 750 760 770 pF1KA0 PVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSAS ::::::::::::::::::::::::::.: CCDS74 --------------------------------GGLTNGSGRYISAAPGAEAKYRSASSTS 520 530 540 780 790 800 810 820 830 pF1KA0 SLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHG :::: :: :: :::::. ::.::::::::::::::::.::::::.. :::.:::::::: CCDS74 SLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHG 550 560 570 580 590 600 840 850 860 870 880 890 pF1KA0 SRFIQLKLERATPAERQLVFNEILQAAYQLNVDVFGNYVIQKFFEFGSLEQKLALAERIR ::::: :::::::::::.:::::::::::: .:::::::::::::::::.:::::: ::: CCDS74 SRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIR 610 620 630 640 650 660 900 910 920 930 940 950 pF1KA0 GHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIEC :::: :::::::::::::::: : :::: .:::.::::::::::::::::::::::::: CCDS74 GHVLPLALQMYGCRVIQKALESISSDQQ--SEMVKELDGHVLKCVKDQNGNHVVQKCIEC 670 680 690 700 710 720 960 970 980 990 1000 1010 pF1KA0 VQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQ ::::::::::::::::::.:::::::::::::::::: .:::::::::::::::::::: CCDS74 VQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQ 730 740 750 760 770 780 1020 1030 1040 1050 1060 1070 pF1KA0 YGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDE ::::::::::::::::::::::.::::.::.::::::::::::::::::::.:::.:::: CCDS74 YGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDE 790 800 810 820 830 840 1080 1090 1100 1110 1120 1130 pF1KA0 VCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHI :: .::::::::::::::::::::::::::.:::.::::.::::::::.::::::::::: CCDS74 VCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHI 850 860 870 880 890 900 1140 1150 1160 pF1KA0 LAKLEKYYMKNGVDLGPICGPPNGII ::::::::.::. ::::: :::::.. CCDS74 LAKLEKYYLKNSPDLGPIGGPPNGML 910 920 1162 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:08:34 2016 done: Thu Nov 3 09:08:35 2016 Total Scan time: 5.900 Total Display time: 0.300 Function used was FASTA [36.3.4 Apr, 2011]