FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0100, 2235 aa 1>>>pF1KA0100 2235 - 2235 aa - 2235 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2247+/-0.00113; mu= 21.0175+/- 0.067 mean_var=96.5635+/-19.009, 0's: 0 Z-trim(104.9): 32 B-trim: 0 in 0/51 Lambda= 0.130517 statistics sampled from 8106 (8119) to 8106 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.249), width: 16 Scan time: 6.800 The best scores are: opt bits E(32554) CCDS32595.1 KIAA0100 gene_id:9703|Hs108|chr17 (2235) 14970 2830.9 0 >>CCDS32595.1 KIAA0100 gene_id:9703|Hs108|chr17 (2235 aa) initn: 14970 init1: 14970 opt: 14970 Z-score: 15224.6 bits: 2830.9 E(32554): 0 Smith-Waterman score: 14970; 100.0% identity (100.0% similar) in 2235 aa overlap (1-2235:1-2235) 10 20 30 40 50 60 pF1KA0 MPLFFSALLVLLLVALSALFLGRWLVVRLATKWCQRKLQAELKIGSFRFFWIQNVSLKFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MPLFFSALLVLLLVALSALFLGRWLVVRLATKWCQRKLQAELKIGSFRFFWIQNVSLKFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QHQQTVEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSDLSAPFSQSAGVDQKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QHQQTVEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSDLSAPFSQSAGVDQKEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 SFSPSLLKIFCQLFSIHVDAINIMVLKVDTSESLWHIQISRSRFLLDSDGKRLICEVSLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SFSPSLLKIFCQLFSIHVDAINIMVLKVDTSESLWHIQISRSRFLLDSDGKRLICEVSLC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KINSKVLKSGQLEDTCLVELSLALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KINSKVLKSGQLEDTCLVELSLALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQSQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 LCQGPSLASKPVPCSEVTENLVEPTLPGLFLLQQLPDQVKVKMENTSVVLSMNSQKRHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LCQGPSLASKPVPCSEVTENLVEPTLPGLFLLQQLPDQVKVKMENTSVVLSMNSQKRHLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 WTLKLLQFLYHRDEDQLPLRSFTANSDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 WTLKLLQFLYHRDEDQLPLRSFTANSDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 QVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPVLKQRKKRTFPQILAPII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPVLKQRKKRTFPQILAPII 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 FSTSISNVNISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 FSTSISNVNISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 CLSRILSLMGPQSGKSAVSRHSSFGESVSLLWKVDLKVEDMNLFTLSALVGASEVRLDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 CLSRILSLMGPQSGKSAVSRHSSFGESVSLLWKVDLKVEDMNLFTLSALVGASEVRLDTL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLDE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AVGVQKWLKGLHQGTRAWASPSPVPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AVGVQKWLKGLHQGTRAWASPSPVPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 RALLTWSLAGLELVALADASFHGPEHVVEQVQELDPGSPFPPEGLDLVIQWCRMLKCNVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RALLTWSLAGLELVALADASFHGPEHVVEQVQELDPGSPFPPEGLDLVIQWCRMLKCNVK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDW 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 HMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGDLDINVRTASKYDDCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 HMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGDLDINVRTASKYDDCC 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 FLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 FLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 MDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QMVSDLSQVTVHLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QMVSDLSQVTVHLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDG 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 DPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAK 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 KPKRGVPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KPKRGVPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 CGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 CGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLK 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 QKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGG 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 MVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVLENQEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVLENQEKE 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 DLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQ 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 LEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQL 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 QLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 TEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQ 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 SGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEV 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 GDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSPEHPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSPEHPVD 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 DIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDF 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 AMAVKRDSRKALVAQVIKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AMAVKRDSRKALVAQVIKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSV 2170 2180 2190 2200 2210 2220 2230 pF1KA0 GDKNPGKKSIFGRRK ::::::::::::::: CCDS32 GDKNPGKKSIFGRRK 2230 2235 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:04:03 2016 done: Wed Nov 2 18:04:04 2016 Total Scan time: 6.800 Total Display time: 0.260 Function used was FASTA [36.3.4 Apr, 2011]