FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0109, 435 aa 1>>>pF1KA0109 435 - 435 aa - 435 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9914+/-0.0013; mu= 13.1325+/- 0.078 mean_var=62.6462+/-12.138, 0's: 0 Z-trim(99.4): 40 B-trim: 0 in 0/49 Lambda= 0.162042 statistics sampled from 5680 (5711) to 5680 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.527), E-opt: 0.2 (0.175), width: 16 Scan time: 2.660 The best scores are: opt bits E(32554) CCDS43177.1 AP2M1 gene_id:1173|Hs108|chr3 ( 435) 2853 676.3 1.6e-194 CCDS43178.1 AP2M1 gene_id:1173|Hs108|chr3 ( 433) 2822 669.0 2.5e-192 CCDS82880.1 AP2M1 gene_id:1173|Hs108|chr3 ( 460) 2686 637.2 9.8e-183 CCDS46008.1 AP1M1 gene_id:8907|Hs108|chr19 ( 435) 1072 259.9 3.6e-69 CCDS77234.1 AP1M2 gene_id:10053|Hs108|chr19 ( 425) 772 189.8 4.5e-48 CCDS45964.1 AP1M2 gene_id:10053|Hs108|chr19 ( 423) 769 189.1 7.3e-48 CCDS12342.1 AP1M1 gene_id:8907|Hs108|chr19 ( 423) 761 187.2 2.7e-47 CCDS5685.1 AP4M1 gene_id:9179|Hs108|chr7 ( 453) 559 140.0 4.7e-33 CCDS6125.1 AP3M2 gene_id:10947|Hs108|chr8 ( 418) 393 101.2 2.1e-21 CCDS7342.1 AP3M1 gene_id:26985|Hs108|chr10 ( 418) 383 98.8 1.1e-20 >>CCDS43177.1 AP2M1 gene_id:1173|Hs108|chr3 (435 aa) initn: 2853 init1: 2853 opt: 2853 Z-score: 3605.6 bits: 676.3 E(32554): 1.6e-194 Smith-Waterman score: 2853; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435) 10 20 30 40 50 60 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK 370 380 390 400 410 420 430 pF1KA0 WVRYIGRSGIYETRC ::::::::::::::: CCDS43 WVRYIGRSGIYETRC 430 >>CCDS43178.1 AP2M1 gene_id:1173|Hs108|chr3 (433 aa) initn: 1931 init1: 1931 opt: 2822 Z-score: 3566.4 bits: 669.0 E(32554): 2.5e-192 Smith-Waterman score: 2822; 99.5% identity (99.5% similar) in 435 aa overlap (1-435:1-433) 10 20 30 40 50 60 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES ::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::: CCDS43 PQNSETGALKTFITQQGIKSQ--TKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK 360 370 380 390 400 410 430 pF1KA0 WVRYIGRSGIYETRC ::::::::::::::: CCDS43 WVRYIGRSGIYETRC 420 430 >>CCDS82880.1 AP2M1 gene_id:1173|Hs108|chr3 (460 aa) initn: 2839 init1: 2686 opt: 2686 Z-score: 3394.2 bits: 637.2 E(32554): 9.8e-183 Smith-Waterman score: 2793; 94.6% identity (94.6% similar) in 460 aa overlap (1-435:1-460) 10 20 30 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIG-------------------------RNAVDAFRVN ::::::::::::::::::::::::: :::::::::: CCDS82 MIGGLFIYNHKGEVLISRVYRDDIGSRQAADSAVFSSSGPFPGEWLEANRRNAVDAFRVN 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 VIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 ISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 TGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 MNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELM 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 RYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 RYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQV 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 ICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFA 370 380 390 400 410 420 400 410 420 430 pF1KA0 PSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC :::::::::::::::::::::::::::::::::::::::: CCDS82 PSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC 430 440 450 460 >>CCDS46008.1 AP1M1 gene_id:8907|Hs108|chr19 (435 aa) initn: 953 init1: 545 opt: 1072 Z-score: 1355.4 bits: 259.9 E(32554): 3.6e-69 Smith-Waterman score: 1072; 38.5% identity (70.9% similar) in 444 aa overlap (5-434:6-433) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV ... . ::.::: : :: :. . :. : ... ... . ::. . . :. . CCDS46 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF :..:..:.:..:.:. ...:: ::::. .:.. :: .. ::.:..:::.:::::::..:: CCDS46 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL ::::.... :. .:::.: :. . . . ::. ..:: ::::::.::.::::. CCDS46 GYPQTTDSKILQEYITQEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVI 130 140 150 160 170 180 190 200 210 220 pF1KA0 ESVNLL------------MSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQG :::::: .: .:.:: ... : . :. .:::::: ..:.:::..... : CCDS46 ESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KA0 KGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILP .: :: .:. ..: ::::::::.:...:.::::::::::::: :: . . CCDS46 RG------KS--KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPL 240 250 260 270 280 290 300 310 320 330 340 pF1KA0 FRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKA . . .... .....: . ::.:: :...:..::.: .... . :..:. CCDS46 IWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KA0 SENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLK .. :::.:: . : :: . :.. : .. . : ..::::..::.: :. ::..::::: CCDS46 ENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLK 350 360 370 380 390 400 410 420 430 pF1KA0 VFEPKLNYSDHDVIKWVRYIGRSGIYETRC ..: : .... ::::: ..: :. : CCDS46 IIEK----SGYQALPWVRYITQNGDYQLRTQ 410 420 430 >>CCDS77234.1 AP1M2 gene_id:10053|Hs108|chr19 (425 aa) initn: 1089 init1: 382 opt: 772 Z-score: 976.5 bits: 189.8 E(32554): 4.5e-48 Smith-Waterman score: 1109; 38.8% identity (74.1% similar) in 433 aa overlap (5-434:6-423) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV .:: . ::. :::: :. :.. . .. : ... ... . .:. . ... :. . CCDS77 MSASAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF :.::..:.:.:..:.::..:. :::: .:. :: .. ::.:..:::..::::::..:: CCDS77 KHSNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL :.::.... :. .::::. : . .:.. ::. ..:: :::::..::.:.::. CCDS77 GFPQTTDSKILQEYITQQSNK----LETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVI 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 ESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGK ::::::.. .:.:: ... : . .: .:::::: ..:.::....: : : : . CCDS77 ESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTG------LSGSKN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 QSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR .:. ..: ::::::::.::..:.::::::::.:::: :: . .. . . .... .. CCDS77 KSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSH 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRM ...:. : :..:: . .:. .:. .:.: .... . :.::: .:...:.:: . CCDS77 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AGMKESQISAEIELLPTNDKKKW-ARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDH : :: . :.. : :. .:.. .::::...::.: :. ::..:::.:..: : . CCDS77 PGGKEYLMRAHFGL-PSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEK----SGY 360 370 380 390 400 420 430 pF1KA0 DVIKWVRYIGRSGIYETRC ... ::::: .:: :. : CCDS77 QALPWVRYITQSGDYQLRTS 410 420 >>CCDS45964.1 AP1M2 gene_id:10053|Hs108|chr19 (423 aa) initn: 1092 init1: 382 opt: 769 Z-score: 972.8 bits: 189.1 E(32554): 7.3e-48 Smith-Waterman score: 1106; 38.6% identity (74.1% similar) in 433 aa overlap (5-434:6-421) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV .:: . ::. :::: :. :.. . .. : ... ... . .:. . ... :. . CCDS45 MSASAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF :.::..:.:.:..:.::..:. :::: .:. :: .. ::.:..:::..::::::..:: CCDS45 KHSNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL :.::.... :. .::::. : . .:.. ::. ..:: :::::..::.:.::. CCDS45 GFPQTTDSKILQEYITQQSNK----LETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVI 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 ESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGK ::::::.. .:.:: ... : . .: .:::::: ..:.::....: :. : . CCDS45 ESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTGR--------SKN 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 QSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR .:. ..: ::::::::.::..:.::::::::.:::: :: . .. . . .... .. CCDS45 KSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSH 230 240 250 260 270 280 300 310 320 330 340 350 pF1KA0 TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRM ...:. : :..:: . .:. .:. .:.: .... . :.::: .:...:.:: . CCDS45 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF 290 300 310 320 330 340 360 370 380 390 400 410 pF1KA0 AGMKESQISAEIELLPTNDKKKW-ARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDH : :: . :.. : :. .:.. .::::...::.: :. ::..:::.:..: : . CCDS45 PGGKEYLMRAHFGL-PSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEK----SGY 350 360 370 380 390 400 420 430 pF1KA0 DVIKWVRYIGRSGIYETRC ... ::::: .:: :. : CCDS45 QALPWVRYITQSGDYQLRTS 410 420 >>CCDS12342.1 AP1M1 gene_id:8907|Hs108|chr19 (423 aa) initn: 1087 init1: 365 opt: 761 Z-score: 962.7 bits: 187.2 E(32554): 2.7e-47 Smith-Waterman score: 1106; 39.6% identity (72.9% similar) in 432 aa overlap (5-434:6-421) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV ... . ::.::: : :: :. . :. : ... ... . ::. . . :. . CCDS12 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF :..:..:.:..:.:. ...:: ::::. .:.. :: .. ::.:..:::.:::::::..:: CCDS12 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL ::::.... :. .:::.: :. . . . ::. ..:: ::::::.::.::::. CCDS12 GYPQTTDSKILQEYITQEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVI 130 140 150 160 170 180 190 200 210 220 230 pF1KA0 ESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGK ::::::.: .:.:: ... : . :. .:::::: ..:.:::..... :.: :: CCDS12 ESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRG------KS-- 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 QSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR .:. ..: ::::::::.:...:.::::::::::::: :: . . . . .... .. CCDS12 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH 230 240 250 260 270 280 300 310 320 330 340 350 pF1KA0 TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRM ...: . ::.:: :...:..::.: .... . :..:. .. :::.:: . CCDS12 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF 290 300 310 320 330 340 360 370 380 390 400 410 pF1KA0 AGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDHD : :: . :.. : .. . : ..::::..::.: :. ::..:::::..: : .. CCDS12 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK----SGYQ 350 360 370 380 390 400 420 430 pF1KA0 VIKWVRYIGRSGIYETRC .. ::::: ..: :. : CCDS12 ALPWVRYITQNGDYQLRTQ 410 420 >>CCDS5685.1 AP4M1 gene_id:9179|Hs108|chr7 (453 aa) initn: 474 init1: 136 opt: 559 Z-score: 706.9 bits: 140.0 E(32554): 4.7e-33 Smith-Waterman score: 643; 29.2% identity (64.1% similar) in 465 aa overlap (1-434:1-452) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIG-RNAVDAFRVNVIHARQQVRSPVTNIAR-TSFFHV ::. .:: . ::. :: . .: : : :.... : .. . .:::. . :.:. CCDS56 MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGD-ESPVVMHHHGRHFIHI 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF ..:...:...:..::. ..:.: .. ... : :...: .:. : .:.::::::.::. CCDS56 RHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDY 60 70 80 90 100 110 120 130 140 150 160 pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQI--------TSQVTGQIGWRREGIKYR- :: :.. : :..:: ... :. . . :.. :.:. . . : .. : CCDS56 GYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 ----RNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQ .::.::::.: ...:.. .:..:.. :.:.. .::.: . : ..:..... . CCDS56 DQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCV--- 180 190 200 210 220 230 230 240 250 260 270 280 pF1KA0 GKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDII- :: .: : .: .:. .::. : :..:.:.: . . ::.::. .:::. . :. CCDS56 GK---SELRGYGP-GIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KA0 -LPFRVIPLVR-EVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKA ::::..: :. . : .:.: . .. .. . : ......: : .. ... . . CCDS56 PLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQ 300 310 320 330 340 350 350 360 370 380 390 pF1KA0 KYKASENAIVWKIKRMAGMKESQISAEIELL-------PTNDKKKWARP----PISMNFE : . .:.:. : . :. : ::.:. ... :.. . : : : :..:: CCDS56 KAELAEGALRWDLPRVQGG--SQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFE 360 370 380 390 400 410 400 410 420 430 pF1KA0 VP-FAPSGLKVRYLKV-FEPKLNYSDHDVIKWVRYIGRSGIYETRC .: . :::.::.:.. :.: : . : ::::....: : : CCDS56 LPRHTCSGLQVRFLRLAFRPCGNANPH---KWVRHLSHSDAYVIRI 420 430 440 450 >>CCDS6125.1 AP3M2 gene_id:10947|Hs108|chr8 (418 aa) initn: 514 init1: 205 opt: 393 Z-score: 497.8 bits: 101.2 E(32554): 2.1e-21 Smith-Waterman score: 578; 26.4% identity (59.3% similar) in 447 aa overlap (1-434:1-417) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQ-QVRSPVTNIARTSFFHVK :: .::. : .:.... . ... ..:.. : : .: . . :: . .. : CCDS61 MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG : .:...:: . .: .:.:::... :.. ::: :: ::.: :..::.:.:.:: : CCDS61 RHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 YPQNSETGALKTFITQQGI-KSQHQTKEEQSQITSQV-TGQIG---WRREGIKYRRNELF .: .:.. :: .: : .. .: .... .:. :::.. ::: :.:: :: . CCDS61 FPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG-MNDKIVIEKQGKGTADET .::.: .. ... .:....:...: . :.:::. .. :: .. CCDS61 FDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRL------------- 190 200 210 220 240 250 260 270 280 pF1KA0 SKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKD--IILPFRV-- .:: .:: :::.....::: .:::::::.:.:. :... . . .: : CCDS61 ---------LDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKH 230 240 250 260 270 290 300 310 320 330 340 pF1KA0 -IPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASE : . . ..:. : :... .. . . : : .. .... .: . CCDS61 NISFRDSSSLGRFEITVGPKQTMGKTI--EGVTVTSQMPKGVLNMSLTPSQGTHTFDPVT 280 290 300 310 320 330 350 360 370 380 390 400 pF1KA0 NAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVF . . : . .. .: .... . : .: : :...:.. .: ::::: : .. CCDS61 KMLSWDVGKINPQKLPSLKGTMSLQAGASKPD-ENPTINLQFKIQQLAISGLKVNRLDMY 340 350 360 370 380 390 410 420 430 pF1KA0 EPKLNYSDHDVIKWVRYIGRSGIYETRC : . .: ..:. ..: ...: CCDS61 GEK-----YKPFKGIKYMTKAGKFQVRT 400 410 >>CCDS7342.1 AP3M1 gene_id:26985|Hs108|chr10 (418 aa) initn: 490 init1: 178 opt: 383 Z-score: 485.2 bits: 98.8 E(32554): 1.1e-20 Smith-Waterman score: 591; 26.2% identity (61.7% similar) in 447 aa overlap (1-434:1-417) 10 20 30 40 50 pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAF-RVNVIHARQQVRSPVTNIARTSFFHVK :: .::. : .:.... . ... ..... : : ... : . :: . . .. . CCDS73 MIHSLFLINCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAADVENVPPVISTPHHYLISIY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 RSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFG :.......: . .: .:.:::... :.. :::. :: ::.: :..::::.:.:: : CCDS73 RDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 YPQNSETGALKTFITQQGI-KSQHQTKEEQSQITSQV-TGQ---IGWRREGIKYRRNELF .: .:.. :: .: : .: .. .:.. . . ::: : ::: :.:: :: . CCDS73 FPLATESNILKELIKPPTILRSVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKYTNNEAY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG-MNDKIVIEKQGKGTADET .::.: .. ... .:... :...: . :::::. ... :: .. CCDS73 FDVVEEIDAIIDKSGSTVFAEIQGVIDACIKLSGMPDLSLSFMNPRL------------- 190 200 210 220 240 250 260 270 280 pF1KA0 SKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKD--IILPFRV-- .:: .:: :.:.....::: .:::::::.:.:. ::.... . .: : CCDS73 ---------LDDVSFHPCIRFKRWESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKH 230 240 250 260 270 290 300 310 320 330 340 pF1KA0 -IPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASE : . .. . .... . :.:. .. . : : . : . .... .:. . CCDS73 SISFKENSSCGRFDITIGPKQNMGKTI--EGITVTVHMPKVVLNMNLTPTQGSYTFDPVT 280 290 300 310 320 330 350 360 370 380 390 400 pF1KA0 NAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVF ....: . ... .: .... ..: .. : : ....:.. .: ::::: : .. CCDS73 KVLTWDVGKITPQKLPSLKGLVNL-QSGAPKPEENPSLNIQFKIQQLAISGLKVNRLDMY 340 350 360 370 380 390 410 420 430 pF1KA0 EPKLNYSDHDVIKWVRYIGRSGIYETRC : . .: :.:. ..: ...: CCDS73 GEK-----YKPFKGVKYVTKAGKFQVRT 400 410 435 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:05:49 2016 done: Wed Nov 2 18:05:49 2016 Total Scan time: 2.660 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]