Result of FASTA (omim) for
pF1KA0109
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0109, 435 aa
1>>>pF1KA0109 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8660+/-0.000568; mu= 13.8829+/- 0.035
mean_var=66.4646+/-13.404, 0's: 0 Z-trim(106.6): 83 B-trim: 576 in 1/51
Lambda= 0.157318
statistics sampled from 14617 (14681) to 14617 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.522), E-opt: 0.2 (0.172), width: 16
Scan time: 5.860
The best scores are: opt bits E(85289)
NP_004059 (OMIM: 601024) AP-2 complex subunit mu i ( 435) 2853 657.2 2.4e-188
NP_001020376 (OMIM: 601024) AP-2 complex subunit m ( 433) 2822 650.1 3.1e-186
NP_001298127 (OMIM: 601024) AP-2 complex subunit m ( 460) 2686 619.3 6.4e-177
NP_001123996 (OMIM: 603535) AP-1 complex subunit m ( 435) 1072 253.0 1.1e-66
XP_016882909 (OMIM: 603535) PREDICTED: AP-1 comple ( 409) 1012 239.3 1.4e-62
NP_001287816 (OMIM: 607309) AP-1 complex subunit m ( 425) 772 184.9 3.5e-46
NP_005489 (OMIM: 607309) AP-1 complex subunit mu-2 ( 423) 769 184.2 5.6e-46
XP_016882910 (OMIM: 603535) PREDICTED: AP-1 comple ( 397) 761 182.4 1.9e-45
NP_115882 (OMIM: 603535) AP-1 complex subunit mu-1 ( 423) 761 182.4 2e-45
NP_004713 (OMIM: 602296,612936) AP-4 complex subun ( 453) 559 136.5 1.3e-31
XP_011514987 (OMIM: 602296,612936) PREDICTED: AP-4 ( 460) 515 126.6 1.4e-28
XP_005250746 (OMIM: 602296,612936) PREDICTED: AP-4 ( 460) 515 126.6 1.4e-28
XP_006716238 (OMIM: 602296,612936) PREDICTED: AP-4 ( 419) 505 124.3 6e-28
NP_006794 (OMIM: 610469) AP-3 complex subunit mu-2 ( 418) 393 98.9 2.7e-20
XP_016868466 (OMIM: 610469) PREDICTED: AP-3 comple ( 418) 393 98.9 2.7e-20
NP_001127768 (OMIM: 610469) AP-3 complex subunit m ( 418) 393 98.9 2.7e-20
NP_036227 (OMIM: 610366) AP-3 complex subunit mu-1 ( 418) 383 96.6 1.3e-19
NP_001307193 (OMIM: 610366) AP-3 complex subunit m ( 418) 383 96.6 1.3e-19
NP_996895 (OMIM: 610366) AP-3 complex subunit mu-1 ( 418) 383 96.6 1.3e-19
NP_001307192 (OMIM: 610366) AP-3 complex subunit m ( 418) 383 96.6 1.3e-19
XP_005250747 (OMIM: 602296,612936) PREDICTED: AP-4 ( 385) 366 92.7 1.8e-18
XP_016868279 (OMIM: 602296,612936) PREDICTED: AP-4 ( 284) 323 82.9 1.1e-15
NP_001307194 (OMIM: 610366) AP-3 complex subunit m ( 364) 263 69.3 1.8e-11
XP_016868468 (OMIM: 610469) PREDICTED: AP-3 comple ( 303) 240 64.1 5.7e-10
XP_016868467 (OMIM: 610469) PREDICTED: AP-3 comple ( 303) 240 64.1 5.7e-10
XP_006720342 (OMIM: 608467) PREDICTED: stonin-2 is ( 898) 241 64.4 1.3e-09
NP_149095 (OMIM: 608467) stonin-2 isoform 1 [Homo ( 905) 241 64.4 1.3e-09
NP_001243359 (OMIM: 608467) stonin-2 isoform 2 [Ho ( 920) 241 64.4 1.4e-09
XP_011535544 (OMIM: 608467) PREDICTED: stonin-2 is ( 955) 241 64.4 1.4e-09
XP_011535543 (OMIM: 608467) PREDICTED: stonin-2 is ( 962) 241 64.4 1.4e-09
XP_011535542 (OMIM: 608467) PREDICTED: stonin-2 is ( 977) 241 64.4 1.4e-09
XP_016868280 (OMIM: 602296,612936) PREDICTED: AP-4 ( 228) 227 61.1 3.4e-09
NP_001185524 (OMIM: 605357) stonin-1 [Homo sapiens ( 735) 195 54.0 1.5e-06
NP_006864 (OMIM: 605357) stonin-1 [Homo sapiens] ( 735) 195 54.0 1.5e-06
>>NP_004059 (OMIM: 601024) AP-2 complex subunit mu isofo (435 aa)
initn: 2853 init1: 2853 opt: 2853 Z-score: 3502.5 bits: 657.2 E(85289): 2.4e-188
Smith-Waterman score: 2853; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK
370 380 390 400 410 420
430
pF1KA0 WVRYIGRSGIYETRC
:::::::::::::::
NP_004 WVRYIGRSGIYETRC
430
>>NP_001020376 (OMIM: 601024) AP-2 complex subunit mu is (433 aa)
initn: 1931 init1: 1931 opt: 2822 Z-score: 3464.5 bits: 650.1 E(85289): 3.1e-186
Smith-Waterman score: 2822; 99.5% identity (99.5% similar) in 435 aa overlap (1-435:1-433)
10 20 30 40 50 60
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES
::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 PQNSETGALKTFITQQGIKSQ--TKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLES
130 140 150 160 170
190 200 210 220 230 240
pF1KA0 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIK
360 370 380 390 400 410
430
pF1KA0 WVRYIGRSGIYETRC
:::::::::::::::
NP_001 WVRYIGRSGIYETRC
420 430
>>NP_001298127 (OMIM: 601024) AP-2 complex subunit mu is (460 aa)
initn: 2839 init1: 2686 opt: 2686 Z-score: 3297.2 bits: 619.3 E(85289): 6.4e-177
Smith-Waterman score: 2793; 94.6% identity (94.6% similar) in 460 aa overlap (1-435:1-460)
10 20 30
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIG-------------------------RNAVDAFRVN
::::::::::::::::::::::::: ::::::::::
NP_001 MIGGLFIYNHKGEVLISRVYRDDIGSRQAADSAVFSSSGPFPGEWLEANRRNAVDAFRVN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 VIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 ISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 TGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 MNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 RYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 ICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFA
370 380 390 400 410 420
400 410 420 430
pF1KA0 PSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC
::::::::::::::::::::::::::::::::::::::::
NP_001 PSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC
430 440 450 460
>>NP_001123996 (OMIM: 603535) AP-1 complex subunit mu-1 (435 aa)
initn: 953 init1: 545 opt: 1072 Z-score: 1317.9 bits: 253.0 E(85289): 1.1e-66
Smith-Waterman score: 1072; 38.5% identity (70.9% similar) in 444 aa overlap (5-434:6-433)
10 20 30 40 50
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV
... . ::.::: : :: :. . :. : ... ... . ::. . . :. .
NP_001 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF
:..:..:.:..:.:. ...:: ::::. .:.. :: .. ::.:..:::.:::::::..::
NP_001 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL
::::.... :. .:::.: :. . . . ::. ..:: ::::::.::.::::.
NP_001 GYPQTTDSKILQEYITQEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVI
130 140 150 160 170
180 190 200 210 220
pF1KA0 ESVNLL------------MSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQG
:::::: .: .:.:: ... : . :. .:::::: ..:.:::..... :
NP_001 ESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 KGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILP
.: :: .:. ..: ::::::::.:...:.::::::::::::: :: . .
NP_001 RG------KS--KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPL
240 250 260 270 280
290 300 310 320 330 340
pF1KA0 FRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKA
. . .... .....: . ::.:: :...:..::.: .... . :..:.
NP_001 IWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVP
290 300 310 320 330 340
350 360 370 380 390 400
pF1KA0 SENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLK
.. :::.:: . : :: . :.. : .. . : ..::::..::.: :. ::..:::::
NP_001 ENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLK
350 360 370 380 390 400
410 420 430
pF1KA0 VFEPKLNYSDHDVIKWVRYIGRSGIYETRC
..: : .... ::::: ..: :. :
NP_001 IIEK----SGYQALPWVRYITQNGDYQLRTQ
410 420 430
>>XP_016882909 (OMIM: 603535) PREDICTED: AP-1 complex su (409 aa)
initn: 891 init1: 545 opt: 1012 Z-score: 1244.7 bits: 239.3 E(85289): 1.4e-62
Smith-Waterman score: 1012; 39.7% identity (71.7% similar) in 403 aa overlap (45-434:21-407)
20 30 40 50 60 70
pF1KA0 LISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVN
::. . . :. .:..:..:.:..:.:.
XP_016 MSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNAC
10 20 30 40 50
80 90 100 110 120 130
pF1KA0 AAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFIT
...:: ::::. .:.. :: .. ::.:..:::.:::::::..::::::.... :. .::
XP_016 VSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYIT
60 70 80 90 100 110
140 150 160 170 180
pF1KA0 QQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLL----------
:.: :. . . . ::. ..:: ::::::.::.::::.::::::
XP_016 QEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLGKYPGVGWLG
120 130 140 150 160
190 200 210 220 230 240
pF1KA0 --MSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIA
.: .:.:: ... : . :. .:::::: ..:.:::..... :.: :: .:.
XP_016 HTVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRG------KS--KSVE
170 180 190 200 210
250 260 270 280 290 300
pF1KA0 IDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLE
..: ::::::::.:...:.::::::::::::: :: . . . . .... .....:
XP_016 LEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 VKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMK
. ::.:: :...:..::.: .... . :..:. .. :::.:: . : :
XP_016 YMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 ESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDHDVIKW
: . :.. : .. . : ..::::..::.: :. ::..:::::..: : .... :
XP_016 EYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK----SGYQALPW
340 350 360 370 380 390
430
pF1KA0 VRYIGRSGIYETRC
:::: ..: :. :
XP_016 VRYITQNGDYQLRTQ
400
>>NP_001287816 (OMIM: 607309) AP-1 complex subunit mu-2 (425 aa)
initn: 1089 init1: 382 opt: 772 Z-score: 950.1 bits: 184.9 E(85289): 3.5e-46
Smith-Waterman score: 1109; 38.8% identity (74.1% similar) in 433 aa overlap (5-434:6-423)
10 20 30 40 50
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV
.:: . ::. :::: :. :.. . .. : ... ... . .:. . ... :. .
NP_001 MSASAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF
:.::..:.:.:..:.::..:. :::: .:. :: .. ::.:..:::..::::::..::
NP_001 KHSNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL
:.::.... :. .::::. : . .:.. ::. ..:: :::::..::.:.::.
NP_001 GFPQTTDSKILQEYITQQSNK----LETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVI
130 140 150 160 170
180 190 200 210 220 230
pF1KA0 ESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGK
::::::.. .:.:: ... : . .: .:::::: ..:.::....: : : : .
NP_001 ESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTG------LSGSKN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 QSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR
.:. ..: ::::::::.::..:.::::::::.:::: :: . .. . . .... ..
NP_001 KSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRM
...:. : :..:: . .:. .:. .:.: .... . :.::: .:...:.:: .
NP_001 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 AGMKESQISAEIELLPTNDKKKW-ARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDH
: :: . :.. : :. .:.. .::::...::.: :. ::..:::.:..: : .
NP_001 PGGKEYLMRAHFGL-PSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEK----SGY
360 370 380 390 400
420 430
pF1KA0 DVIKWVRYIGRSGIYETRC
... ::::: .:: :. :
NP_001 QALPWVRYITQSGDYQLRTS
410 420
>>NP_005489 (OMIM: 607309) AP-1 complex subunit mu-2 iso (423 aa)
initn: 1092 init1: 382 opt: 769 Z-score: 946.4 bits: 184.2 E(85289): 5.6e-46
Smith-Waterman score: 1106; 38.6% identity (74.1% similar) in 433 aa overlap (5-434:6-421)
10 20 30 40 50
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV
.:: . ::. :::: :. :.. . .. : ... ... . .:. . ... :. .
NP_005 MSASAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF
:.::..:.:.:..:.::..:. :::: .:. :: .. ::.:..:::..::::::..::
NP_005 KHSNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL
:.::.... :. .::::. : . .:.. ::. ..:: :::::..::.:.::.
NP_005 GFPQTTDSKILQEYITQQSNK----LETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVI
130 140 150 160 170
180 190 200 210 220 230
pF1KA0 ESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGK
::::::.. .:.:: ... : . .: .:::::: ..:.::....: :. : .
NP_005 ESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTGR--------SKN
180 190 200 210 220
240 250 260 270 280 290
pF1KA0 QSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR
.:. ..: ::::::::.::..:.::::::::.:::: :: . .. . . .... ..
NP_005 KSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSH
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRM
...:. : :..:: . .:. .:. .:.: .... . :.::: .:...:.:: .
NP_005 SRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 AGMKESQISAEIELLPTNDKKKW-ARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDH
: :: . :.. : :. .:.. .::::...::.: :. ::..:::.:..: : .
NP_005 PGGKEYLMRAHFGL-PSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEK----SGY
350 360 370 380 390 400
420 430
pF1KA0 DVIKWVRYIGRSGIYETRC
... ::::: .:: :. :
NP_005 QALPWVRYITQSGDYQLRTS
410 420
>>XP_016882910 (OMIM: 603535) PREDICTED: AP-1 complex su (397 aa)
initn: 1032 init1: 365 opt: 761 Z-score: 937.1 bits: 182.4 E(85289): 1.9e-45
Smith-Waterman score: 1046; 40.9% identity (73.9% similar) in 391 aa overlap (45-434:21-395)
20 30 40 50 60 70
pF1KA0 LISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVN
::. . . :. .:..:..:.:..:.:.
XP_016 MSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNAC
10 20 30 40 50
80 90 100 110 120 130
pF1KA0 AAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFIT
...:: ::::. .:.. :: .. ::.:..:::.:::::::..::::::.... :. .::
XP_016 VSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYIT
60 70 80 90 100 110
140 150 160 170 180 190
pF1KA0 QQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSA
:.: :. . . . ::. ..:: ::::::.::.::::.::::::.: .:.:: .
XP_016 QEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRS
120 130 140 150 160
200 210 220 230 240 250
pF1KA0 HVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRL
.. : . :. .:::::: ..:.:::..... :.: :: .:. ..: :::::::
XP_016 EIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRG------KS--KSVELEDVKFHQCVRL
170 180 190 200 210
260 270 280 290 300 310
pF1KA0 SKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPS
:.:...:.::::::::::::: :: . . . . .... .....: . ::.::
XP_016 SRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA0 LLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLP
:...:..::.: .... . :..:. .. :::.:: . : :: . :.. :
XP_016 STANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA0 TNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYET
.. . : ..::::..::.: :. ::..:::::..: : .... ::::: ..: :.
XP_016 VEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQL
340 350 360 370 380 390
pF1KA0 RC
:
XP_016 RTQ
>>NP_115882 (OMIM: 603535) AP-1 complex subunit mu-1 iso (423 aa)
initn: 1087 init1: 365 opt: 761 Z-score: 936.6 bits: 182.4 E(85289): 2e-45
Smith-Waterman score: 1106; 39.6% identity (72.9% similar) in 432 aa overlap (5-434:6-421)
10 20 30 40 50
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHV
... . ::.::: : :: :. . :. : ... ... . ::. . . :. .
NP_115 MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF
:..:..:.:..:.:. ...:: ::::. .:.. :: .. ::.:..:::.:::::::..::
NP_115 KHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVL
::::.... :. .:::.: :. . . . ::. ..:: ::::::.::.::::.
NP_115 GYPQTTDSKILQEYITQEG----HKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVI
130 140 150 160 170
180 190 200 210 220 230
pF1KA0 ESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGK
::::::.: .:.:: ... : . :. .:::::: ..:.:::..... :.: ::
NP_115 ESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRG------KS--
180 190 200 210 220
240 250 260 270 280 290
pF1KA0 QSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGR
.:. ..: ::::::::.:...:.::::::::::::: :: . . . . .... ..
NP_115 KSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSH
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 TKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRM
...: . ::.:: :...:..::.: .... . :..:. .. :::.:: .
NP_115 SRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSF
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 AGMKESQISAEIELLPTNDKKKWARPPISMNFEVP-FAPSGLKVRYLKVFEPKLNYSDHD
: :: . :.. : .. . : ..::::..::.: :. ::..:::::..: : ..
NP_115 PGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEK----SGYQ
350 360 370 380 390 400
420 430
pF1KA0 VIKWVRYIGRSGIYETRC
.. ::::: ..: :. :
NP_115 ALPWVRYITQNGDYQLRTQ
410 420
>>NP_004713 (OMIM: 602296,612936) AP-4 complex subunit m (453 aa)
initn: 474 init1: 136 opt: 559 Z-score: 688.4 bits: 136.5 E(85289): 1.3e-31
Smith-Waterman score: 643; 29.2% identity (64.1% similar) in 465 aa overlap (1-434:1-452)
10 20 30 40 50
pF1KA0 MIGGLFIYNHKGEVLISRVYRDDIG-RNAVDAFRVNVIHARQQVRSPVTNIAR-TSFFHV
::. .:: . ::. :: . .: : : :.... : .. . .:::. . :.:.
NP_004 MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGD-ESPVVMHHHGRHFIHI
10 20 30 40 50
60 70 80 90 100 110
pF1KA0 KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF
..:...:...:..::. ..:.: .. ... : :...: .:. : .:.::::::.::.
NP_004 RHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEVLDY
60 70 80 90 100 110
120 130 140 150 160
pF1KA0 GYPQNSETGALKTFITQQGIKSQHQTKEEQSQI--------TSQVTGQIGWRREGIKYR-
:: :.. : :..:: ... :. . . :.. :.:. . . : .. :
NP_004 GYVQTTSTEMLRNFIQTEAVVSKPFSLFDLSSVGLFGAETQQSKVAPSSAASRPVLSSRS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KA0 ----RNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQ
.::.::::.: ...:.. .:..:.. :.:.. .::.: . : ..:..... .
NP_004 DQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEFCV---
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 GKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDII-
:: .: : .: .:. .::. : :..:.:.: . . ::.::. .:::. . :.
NP_004 GK---SELRGYGP-GIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRYQLSDDLPS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA0 -LPFRVIPLVR-EVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKA
::::..: :. . : .:.: . .. .. . : ......: : .. ... . .
NP_004 PLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHLPLPRGVVSLSQELSSPEQ
300 310 320 330 340 350
350 360 370 380 390
pF1KA0 KYKASENAIVWKIKRMAGMKESQISAEIELL-------PTNDKKKWARP----PISMNFE
: . .:.:. : . :. : ::.:. ... :.. . : : : :..::
NP_004 KAELAEGALRWDLPRVQGG--SQLSGLFQMDVPGPPGPPSHGLSTSASPLGLGPASLSFE
360 370 380 390 400 410
400 410 420 430
pF1KA0 VP-FAPSGLKVRYLKV-FEPKLNYSDHDVIKWVRYIGRSGIYETRC
.: . :::.::.:.. :.: : . : ::::....: : :
NP_004 LPRHTCSGLQVRFLRLAFRPCGNANPH---KWVRHLSHSDAYVIRI
420 430 440 450
435 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:05:49 2016 done: Wed Nov 2 18:05:50 2016
Total Scan time: 5.860 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]