FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0128, 427 aa 1>>>pF1KA0128 427 - 427 aa - 427 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3541+/-0.000521; mu= -0.9740+/- 0.032 mean_var=240.1731+/-47.122, 0's: 0 Z-trim(114.8): 168 B-trim: 0 in 0/57 Lambda= 0.082758 statistics sampled from 24613 (24781) to 24613 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.291), width: 16 Scan time: 7.840 The best scores are: opt bits E(85289) XP_006724813 (OMIM: 300683) PREDICTED: septin-6 is ( 427) 2775 344.8 2.6e-94 NP_665799 (OMIM: 300683) septin-6 isoform A [Homo ( 427) 2775 344.8 2.6e-94 NP_665798 (OMIM: 300683) septin-6 isoform A [Homo ( 427) 2775 344.8 2.6e-94 NP_665801 (OMIM: 300683) septin-6 isoform D [Homo ( 429) 2775 344.8 2.6e-94 XP_006724811 (OMIM: 300683) PREDICTED: septin-6 is ( 431) 2775 344.8 2.6e-94 NP_055944 (OMIM: 300683) septin-6 isoform B [Homo ( 434) 2775 344.8 2.6e-94 XP_011529620 (OMIM: 300683) PREDICTED: septin-6 is ( 469) 2775 344.8 2.7e-94 XP_005262457 (OMIM: 300683) PREDICTED: septin-6 is ( 491) 2775 344.8 2.8e-94 XP_011529619 (OMIM: 300683) PREDICTED: septin-6 is ( 526) 2775 344.8 3e-94 XP_016863893 (OMIM: 612887) PREDICTED: septin-11 i ( 425) 2332 291.9 2.1e-78 XP_016863892 (OMIM: 612887) PREDICTED: septin-11 i ( 429) 2332 291.9 2.1e-78 NP_060713 (OMIM: 612887) septin-11 isoform 2 [Homo ( 429) 2332 291.9 2.1e-78 XP_016863891 (OMIM: 612887) PREDICTED: septin-11 i ( 435) 2322 290.7 5e-78 NP_001293076 (OMIM: 612887) septin-11 isoform 1 [H ( 439) 2322 290.7 5e-78 XP_016863890 (OMIM: 612887) PREDICTED: septin-11 i ( 439) 2322 290.7 5e-78 XP_016863889 (OMIM: 612887) PREDICTED: septin-11 i ( 439) 2322 290.7 5e-78 NP_055961 (OMIM: 608418) septin-8 isoform b [Homo ( 429) 2170 272.5 1.4e-72 NP_001092281 (OMIM: 608418) septin-8 isoform a [Ho ( 483) 2170 272.6 1.6e-72 NP_001092282 (OMIM: 608418) septin-8 isoform c [Ho ( 442) 2163 271.7 2.6e-72 XP_005271984 (OMIM: 608418) PREDICTED: septin-8 is ( 482) 2163 271.7 2.8e-72 NP_001287728 (OMIM: 608418) septin-8 isoform f [Ho ( 427) 2143 269.3 1.3e-71 XP_005271985 (OMIM: 608418) PREDICTED: septin-8 is ( 481) 2143 269.3 1.5e-71 NP_001287727 (OMIM: 608418) septin-8 isoform e [Ho ( 440) 2136 268.5 2.4e-71 XP_016864743 (OMIM: 608418) PREDICTED: septin-8 is ( 480) 2136 268.5 2.6e-71 NP_848699 (OMIM: 611737) septin-10 isoform 2 [Homo ( 431) 2087 262.6 1.4e-69 NP_001308429 (OMIM: 611737) septin-10 isoform 6 [H ( 427) 2080 261.8 2.4e-69 XP_011509001 (OMIM: 611737) PREDICTED: septin-10 i ( 521) 2080 261.9 2.8e-69 NP_001308444 (OMIM: 611737) septin-10 isoform 21 [ ( 422) 2066 260.1 7.7e-69 NP_001308443 (OMIM: 611737) septin-10 isoform 20 [ ( 439) 2066 260.1 7.9e-69 NP_653311 (OMIM: 611737) septin-10 isoform 1 [Homo ( 454) 2066 260.1 8.1e-69 NP_001308442 (OMIM: 611737) septin-10 isoform 19 [ ( 441) 2059 259.3 1.4e-68 NP_001308441 (OMIM: 611737) septin-10 isoform 18 [ ( 450) 2059 259.3 1.4e-68 XP_006712380 (OMIM: 611737) PREDICTED: septin-10 i ( 488) 2059 259.3 1.5e-68 XP_011509000 (OMIM: 611737) PREDICTED: septin-10 i ( 529) 2059 259.3 1.6e-68 XP_011509005 (OMIM: 611737) PREDICTED: septin-10 i ( 535) 2059 259.4 1.6e-68 NP_001308427 (OMIM: 611737) septin-10 isoform 4 [H ( 544) 2059 259.4 1.7e-68 XP_006714322 (OMIM: 612887) PREDICTED: septin-11 i ( 372) 2055 258.8 1.7e-68 NP_001308438 (OMIM: 611737) septin-10 isoform 15 [ ( 412) 2053 258.6 2.2e-68 NP_001308430 (OMIM: 611737) septin-10 isoform 7 [H ( 408) 2046 257.7 3.9e-68 XP_011509002 (OMIM: 611737) PREDICTED: septin-10 i ( 502) 2046 257.8 4.6e-68 NP_001092283 (OMIM: 608418) septin-8 isoform d [Ho ( 369) 1909 241.3 3e-63 XP_011541590 (OMIM: 608418) PREDICTED: septin-8 is ( 423) 1909 241.4 3.4e-63 XP_005271988 (OMIM: 608418) PREDICTED: septin-8 is ( 423) 1909 241.4 3.4e-63 XP_016864747 (OMIM: 608418) PREDICTED: septin-8 is ( 382) 1902 240.5 5.6e-63 XP_016864744 (OMIM: 608418) PREDICTED: septin-8 is ( 422) 1902 240.5 6e-63 XP_016864750 (OMIM: 608418) PREDICTED: septin-8 is ( 367) 1882 238.1 2.8e-62 XP_016864746 (OMIM: 608418) PREDICTED: septin-8 is ( 421) 1882 238.1 3.1e-62 XP_016864745 (OMIM: 608418) PREDICTED: septin-8 is ( 421) 1882 238.1 3.1e-62 XP_016864749 (OMIM: 608418) PREDICTED: septin-8 is ( 380) 1875 237.3 5.2e-62 XP_016864748 (OMIM: 608418) PREDICTED: septin-8 is ( 380) 1875 237.3 5.2e-62 >>XP_006724813 (OMIM: 300683) PREDICTED: septin-6 isofor (427 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1814.3 bits: 344.8 E(85289): 2.6e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: XP_006 RDKEKKN >>NP_665799 (OMIM: 300683) septin-6 isoform A [Homo sapi (427 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1814.3 bits: 344.8 E(85289): 2.6e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: NP_665 RDKEKKN >>NP_665798 (OMIM: 300683) septin-6 isoform A [Homo sapi (427 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1814.3 bits: 344.8 E(85289): 2.6e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: NP_665 RDKEKKN >>NP_665801 (OMIM: 300683) septin-6 isoform D [Homo sapi (429 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1814.3 bits: 344.8 E(85289): 2.6e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_665 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: NP_665 RDKEKKNFF >>XP_006724811 (OMIM: 300683) PREDICTED: septin-6 isofor (431 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1814.3 bits: 344.8 E(85289): 2.6e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: XP_006 RDKEKKNLGFL 430 >>NP_055944 (OMIM: 300683) septin-6 isoform B [Homo sapi (434 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1814.2 bits: 344.8 E(85289): 2.6e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: NP_055 RDKEKKNNPWLCTE 430 >>XP_011529620 (OMIM: 300683) PREDICTED: septin-6 isofor (469 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1813.8 bits: 344.8 E(85289): 2.7e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: XP_011 RDKEKKNSYCFTVNSAVCCMLHETQGPVIHGCVLNSIPRYSWTGLHLAF 430 440 450 460 >>XP_005262457 (OMIM: 300683) PREDICTED: septin-6 isofor (491 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1813.5 bits: 344.8 E(85289): 2.8e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: XP_005 RDKEKKNSYCFTVNSAVCCMLHETQGPVWASCRHPFPAQQSWASLSLISPLTCLGGIQSN 430 440 450 460 470 480 >>XP_011529619 (OMIM: 300683) PREDICTED: septin-6 isofor (526 aa) initn: 2775 init1: 2775 opt: 2775 Z-score: 1813.1 bits: 344.8 E(85289): 3e-94 Smith-Waterman score: 2775; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK 370 380 390 400 410 420 pF1KA0 RDKEKKN ::::::: XP_011 RDKEKKNSYCFTVNSAVCCMLHETQGPAFFNLVFSSCTKSKGEDCHYRRVRVPYCLKSEI 430 440 450 460 470 480 >>XP_016863893 (OMIM: 612887) PREDICTED: septin-11 isofo (425 aa) initn: 2357 init1: 2281 opt: 2332 Z-score: 1528.5 bits: 291.9 E(85289): 2.1e-78 Smith-Waterman score: 2332; 82.6% identity (95.5% similar) in 425 aa overlap (3-427:2-425) 10 20 30 40 50 60 pF1KA0 MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMD :. ..: .: :.. :.::::::::::::::::.:::::::::::::::.::::::: XP_016 MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMD 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 TLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVE ::::::::..::::..:::.:.. .:.:::::::::::::.::::::::::.:::::::: XP_016 TLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 FIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNII .:::::::::::::::.: : .:::.:::.:::::::::::::::::::::::::::::: XP_016 YIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNII 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 PIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGS :::::::.:.:.:: ::: :: ::::::::::::::::.:.:::::.::..::::::.:: XP_016 PIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 TEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR :::.:::::: .:::::::.:::::: ::::::::::::::::::::::::::::::::: XP_016 TEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRR 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEA :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_016 CKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEA 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 EKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLK ::::::::: ::. ::.::::.::::: :..::: :...:.::.:::::..:.:..:: : XP_016 EKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKAAAQLLQSQAQQSGAQQT-K 360 370 380 390 400 410 pF1KA0 RDKEKKN .::.::: XP_016 KDKDKKN 420 427 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:10:04 2016 done: Wed Nov 2 18:10:06 2016 Total Scan time: 7.840 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]