FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0129, 442 aa 1>>>pF1KA0129 442 - 442 aa - 442 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0496+/-0.000351; mu= 14.9392+/- 0.022 mean_var=109.2655+/-22.059, 0's: 0 Z-trim(116.8): 240 B-trim: 195 in 1/56 Lambda= 0.122697 statistics sampled from 28003 (28267) to 28003 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.331), width: 16 Scan time: 9.510 The best scores are: opt bits E(85289) XP_016870842 (OMIM: 606556) PREDICTED: tripartite ( 442) 3024 546.1 6.6e-155 XP_016870841 (OMIM: 606556) PREDICTED: tripartite ( 442) 3024 546.1 6.6e-155 XP_005252377 (OMIM: 606556) PREDICTED: tripartite ( 442) 3024 546.1 6.6e-155 NP_055603 (OMIM: 606556) tripartite motif-containi ( 442) 3024 546.1 6.6e-155 NP_150088 (OMIM: 606556) tripartite motif-containi ( 442) 3024 546.1 6.6e-155 XP_006717401 (OMIM: 606556) PREDICTED: tripartite ( 392) 2515 456.0 8.1e-128 XP_011517546 (OMIM: 606556) PREDICTED: tripartite ( 285) 1960 357.6 2.4e-98 XP_016870843 (OMIM: 606556) PREDICTED: tripartite ( 297) 1776 325.1 1.6e-88 NP_006461 (OMIM: 609505) tripartite motif-containi ( 564) 394 80.7 1.1e-14 NP_976040 (OMIM: 609315) tripartite motif-containi ( 303) 330 69.1 1.8e-11 NP_976041 (OMIM: 609315) tripartite motif-containi ( 303) 330 69.1 1.8e-11 NP_976039 (OMIM: 609315) tripartite motif-containi ( 303) 330 69.1 1.8e-11 XP_016865392 (OMIM: 609315) PREDICTED: tripartite ( 303) 330 69.1 1.8e-11 NP_976042 (OMIM: 609315) tripartite motif-containi ( 329) 330 69.1 1.9e-11 NP_976038 (OMIM: 609315) tripartite motif-containi ( 511) 330 69.3 2.6e-11 NP_005073 (OMIM: 600453) E3 ubiquitin/ISG15 ligase ( 630) 325 68.5 5.7e-11 NP_001184162 (OMIM: 613590) butyrophilin subfamily ( 466) 323 68.0 5.8e-11 NP_001184168 (OMIM: 613591) butyrophilin subfamily ( 313) 320 67.4 6.3e-11 XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 320 67.4 6.3e-11 NP_008980 (OMIM: 613590) butyrophilin subfamily 2 ( 527) 323 68.1 6.4e-11 NP_001317412 (OMIM: 616755) E3 ubiquitin-protein l ( 354) 320 67.4 6.9e-11 NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 322 67.9 7.1e-11 NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 321 67.7 7.6e-11 NP_853509 (OMIM: 613591) butyrophilin subfamily 2 ( 407) 320 67.4 7.6e-11 XP_016865656 (OMIM: 613591) PREDICTED: butyrophili ( 407) 320 67.4 7.6e-11 XP_005248855 (OMIM: 613591) PREDICTED: butyrophili ( 407) 320 67.4 7.6e-11 XP_011512531 (OMIM: 613591) PREDICTED: butyrophili ( 461) 320 67.5 8.4e-11 XP_016865655 (OMIM: 613591) PREDICTED: butyrophili ( 461) 320 67.5 8.4e-11 XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 321 67.7 8.5e-11 NP_001184166 (OMIM: 613591) butyrophilin subfamily ( 523) 320 67.5 9.2e-11 XP_011512530 (OMIM: 613591) PREDICTED: butyrophili ( 523) 320 67.5 9.2e-11 XP_005248854 (OMIM: 613591) PREDICTED: butyrophili ( 523) 320 67.5 9.2e-11 XP_006715016 (OMIM: 613591) PREDICTED: butyrophili ( 523) 320 67.5 9.2e-11 NP_008926 (OMIM: 613591) butyrophilin subfamily 2 ( 523) 320 67.5 9.2e-11 XP_016857119 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 544) 317 67.0 1.4e-10 XP_011538873 (OMIM: 111620,111750,609017) PREDICTE ( 468) 315 66.6 1.6e-10 XP_011538872 (OMIM: 111620,111750,609017) PREDICTE ( 475) 315 66.6 1.6e-10 XP_006710376 (OMIM: 111620,111750,609017) PREDICTE ( 475) 315 66.6 1.6e-10 NP_061008 (OMIM: 111620,111750,609017) erythroid m ( 475) 315 66.6 1.6e-10 NP_001017922 (OMIM: 111620,111750,609017) erythroi ( 475) 315 66.6 1.6e-10 NP_258411 (OMIM: 611041) tripartite motif-containi ( 638) 311 66.0 3.2e-10 NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 304 64.7 6.6e-10 XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 304 64.8 7.5e-10 NP_150631 (OMIM: 189960,300000,300552) E3 ubiquiti ( 629) 304 64.8 7.5e-10 XP_016885028 (OMIM: 189960,300000,300552) PREDICTE ( 629) 304 64.8 7.5e-10 XP_016885027 (OMIM: 189960,300000,300552) PREDICTE ( 629) 304 64.8 7.5e-10 XP_016885026 (OMIM: 189960,300000,300552) PREDICTE ( 629) 304 64.8 7.5e-10 XP_016885024 (OMIM: 189960,300000,300552) PREDICTE ( 680) 304 64.8 7.9e-10 XP_006724555 (OMIM: 189960,300000,300552) PREDICTE ( 718) 304 64.8 8.3e-10 XP_011543828 (OMIM: 189960,300000,300552) PREDICTE ( 718) 304 64.8 8.3e-10 >>XP_016870842 (OMIM: 606556) PREDICTED: tripartite moti (442 aa) initn: 3024 init1: 3024 opt: 3024 Z-score: 2902.0 bits: 546.1 E(85289): 6.6e-155 Smith-Waterman score: 3024; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KA0 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 370 380 390 400 410 420 430 440 pF1KA0 FQEPLYPALRLWEGAISIPRLP :::::::::::::::::::::: XP_016 FQEPLYPALRLWEGAISIPRLP 430 440 >>XP_016870841 (OMIM: 606556) PREDICTED: tripartite moti (442 aa) initn: 3024 init1: 3024 opt: 3024 Z-score: 2902.0 bits: 546.1 E(85289): 6.6e-155 Smith-Waterman score: 3024; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KA0 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 370 380 390 400 410 420 430 440 pF1KA0 FQEPLYPALRLWEGAISIPRLP :::::::::::::::::::::: XP_016 FQEPLYPALRLWEGAISIPRLP 430 440 >>XP_005252377 (OMIM: 606556) PREDICTED: tripartite moti (442 aa) initn: 3024 init1: 3024 opt: 3024 Z-score: 2902.0 bits: 546.1 E(85289): 6.6e-155 Smith-Waterman score: 3024; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KA0 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 370 380 390 400 410 420 430 440 pF1KA0 FQEPLYPALRLWEGAISIPRLP :::::::::::::::::::::: XP_005 FQEPLYPALRLWEGAISIPRLP 430 440 >>NP_055603 (OMIM: 606556) tripartite motif-containing p (442 aa) initn: 3024 init1: 3024 opt: 3024 Z-score: 2902.0 bits: 546.1 E(85289): 6.6e-155 Smith-Waterman score: 3024; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KA0 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 370 380 390 400 410 420 430 440 pF1KA0 FQEPLYPALRLWEGAISIPRLP :::::::::::::::::::::: NP_055 FQEPLYPALRLWEGAISIPRLP 430 440 >>NP_150088 (OMIM: 606556) tripartite motif-containing p (442 aa) initn: 3024 init1: 3024 opt: 3024 Z-score: 2902.0 bits: 546.1 E(85289): 6.6e-155 Smith-Waterman score: 3024; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442) 10 20 30 40 50 60 pF1KA0 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 370 380 390 400 410 420 430 440 pF1KA0 FQEPLYPALRLWEGAISIPRLP :::::::::::::::::::::: NP_150 FQEPLYPALRLWEGAISIPRLP 430 440 >>XP_006717401 (OMIM: 606556) PREDICTED: tripartite moti (392 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 2415.8 bits: 456.0 E(85289): 8.1e-128 Smith-Waterman score: 2515; 99.2% identity (100.0% similar) in 376 aa overlap (67-442:17-392) 40 50 60 70 80 90 pF1KA0 RRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDA ...::::::::::::::::::::::::::: XP_006 MTLGKLPHLQMPPLEKNTRKLSQECLKQLAIKKQQHIDNITQIEDA 10 20 30 40 100 110 120 130 140 150 pF1KA0 TEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLD 50 60 70 80 90 100 160 170 180 190 200 210 pF1KA0 IMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLV 110 120 130 140 150 160 220 230 240 250 260 270 pF1KA0 EAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTM 170 180 190 200 210 220 280 290 300 310 320 330 pF1KA0 HARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWW 230 240 250 260 270 280 340 350 360 370 380 390 pF1KA0 VGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLD 290 300 310 320 330 340 400 410 420 430 440 pF1KA0 YEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRLP :::::::::::::::::::::::::::::::::::::::::::::: XP_006 YEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRLP 350 360 370 380 390 >>XP_011517546 (OMIM: 606556) PREDICTED: tripartite moti (285 aa) initn: 1960 init1: 1960 opt: 1960 Z-score: 1886.7 bits: 357.6 E(85289): 2.4e-98 Smith-Waterman score: 1960; 100.0% identity (100.0% similar) in 285 aa overlap (158-442:1-285) 130 140 150 160 170 180 pF1KA0 LAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQE :::::::::::::::::::::::::::::: XP_011 MNDLSNRVWSISQEPDPVQRLQAYTATEQE 10 20 30 190 200 210 220 230 240 pF1KA0 MQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKP 40 50 60 70 80 90 250 260 270 280 290 300 pF1KA0 GTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDA 100 110 120 130 140 150 310 320 330 340 350 360 pF1KA0 LWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRY 160 170 180 190 200 210 370 380 390 400 410 420 pF1KA0 DLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYP 220 230 240 250 260 270 430 440 pF1KA0 ALRLWEGAISIPRLP ::::::::::::::: XP_011 ALRLWEGAISIPRLP 280 >>XP_016870843 (OMIM: 606556) PREDICTED: tripartite moti (297 aa) initn: 1774 init1: 1774 opt: 1776 Z-score: 1710.4 bits: 325.1 E(85289): 1.6e-88 Smith-Waterman score: 1776; 97.4% identity (97.8% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KA0 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV ::::::::::::::::::::::::: . : XP_016 DPSSTKPGTLLKTSPSPERSLLLKYQEMEISTPQKSSSCAFLFTIPKGDPLSRLLGL 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ >>NP_006461 (OMIM: 609505) tripartite motif-containing p (564 aa) initn: 198 init1: 80 opt: 394 Z-score: 384.6 bits: 80.7 E(85289): 1.1e-14 Smith-Waterman score: 412; 26.7% identity (55.4% similar) in 453 aa overlap (14-438:120-545) 10 20 30 40 pF1KA0 MAGAATGSRTPGRSELVEGCGWR-CPEHGDRVAELFCRRCRRC .: :. .:: :: : . .. :: ..: NP_006 VKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSA-FCCPDQQC 90 100 110 120 130 140 50 60 70 80 90 100 pF1KA0 VCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKA .: : : :: . ..:.:: . .. .: :: .... ... :.: .:.: NP_006 ICQDC--CQEHSGHTI-VSLDAARRDKEAELQCT-QLDLERKLKLN-----ENAISRLQA 150 160 170 180 190 110 120 130 140 150 pF1KA0 NAES---SKTWLKG----KFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQL : .: : . .:. .: :: . . .: . :.... : .:. ::.. . .: NP_006 NQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALS----QANGIKAHL 200 210 220 230 240 250 160 170 180 190 200 210 pF1KA0 DIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCH-PVPLSFEPVKSFFKG . : . . . ..:. : . : : ... .. . : . .:. ..: NP_006 EY------RSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSG 260 270 280 290 300 220 230 240 250 260 pF1KA0 LVEAV-ESTLQTPLDIRLKESINCQLSDPSS-------TKPGTLLK-----TSPSPE-RS . ... :::.. :.: :. . .:.. :. :. ..... ..: : : NP_006 IRKVITESTVHL---IQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTRE 310 320 330 340 350 360 270 280 290 300 310 pF1KA0 LLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVL--RFDALWQVLARDCFA .:.:: :.:::: : :::. . : . : : : :: :::... . NP_006 QFLQYAYDITFDPDTAHKYLRLQEENRKVT-NTTPWEHPYPDLPSRFLHWRQVLSQQSLY 370 380 390 400 410 420 320 330 340 350 360 370 pF1KA0 TGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQ :.:.::.. ::: .:: . .. :.: . .. : :: :. :. :... . NP_006 LHRYYFEVEI--FGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDM 430 440 450 460 470 480 380 390 400 410 420 430 pF1KA0 RSRLRPRDDLDRLGVFLDYEAGVLAFYDVT-GGMSHLHTFRATFQEPLYPALRL--WEGA .. :. . ::::..:. .:.:.:: : :. .: : :.::.: :. : :.: NP_006 ETPLKA-GPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENA 490 500 510 520 530 540 440 pF1KA0 ISIPRLP : : NP_006 IRIVDLGEEPEKPAPSLVGTAP 550 560 >>NP_976040 (OMIM: 609315) tripartite motif-containing p (303 aa) initn: 283 init1: 155 opt: 330 Z-score: 326.9 bits: 69.1 E(85289): 1.8e-11 Smith-Waterman score: 342; 30.6% identity (54.8% similar) in 330 aa overlap (104-427:3-288) 80 90 100 110 120 130 pF1KA0 ECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFI ::. : . ..: :: .: :.:. ... NP_976 MAAEQEK--VGAEFQALRAFLVEQEG---RLL 10 20 140 150 160 170 180 pF1KA0 DKNTQLTLQVYREQADSCREQLDI----MNDLSNRVWSISQEPDPVQRLQAYTATEQEMQ . .:. .: ..: .. :: . .. ::... .:.:: .. :: . .: .. NP_976 GRLEELSREVAQKQNENL-AQLGVEITQLSKLSSQIQETAQKPD-LDFLQEFKSTLSR-- 30 40 50 60 70 80 190 200 210 220 230 240 pF1KA0 QQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPL-DIRLKESINCQLSDPSSTKPG : :: . .:. .: : ... . .. :: . :. NP_976 --------CSNVP-GPKPT---------TVSSEMKNKVWNVSLKTFV---LKG------- 90 100 110 250 260 270 280 290 300 pF1KA0 TLLKTSPSPERSLLLKYARTP-TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDA .:: :. : : .. :::::: . :: :: : :: : .. : :::. NP_976 -MLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDT 120 130 140 150 160 170 310 320 330 340 350 360 pF1KA0 LWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRY .::: :..:::.:::.: . :: :.: :.::.: . . .. : :. NP_976 NTRVLASCGFSSGRHHWEVEVG-SKDGWAFGVARESVRRKGLTP---FTPEEGVWALQLN 180 190 200 210 220 230 370 380 390 400 410 420 pF1KA0 DLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYP .::: . .:: : :.:. : :: :.:...:: : : ::.:::..::: ..: NP_976 GGQYWAVTSPERSPLSC-GHLSRVRVALDLEVGAVSFYAVED-MRHLYTFRVNFQERVFP 240 250 260 270 280 430 440 pF1KA0 ALRLWEGAISIPRLP NP_976 LFSVCSTGTYLRIWP 290 300 442 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:38:14 2016 done: Sat Nov 5 06:38:16 2016 Total Scan time: 9.510 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]