FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0159, 1401 aa 1>>>pF1KA0159 1401 - 1401 aa - 1401 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0538+/-0.000434; mu= 20.2123+/- 0.027 mean_var=96.5887+/-18.834, 0's: 0 Z-trim(111.3): 26 B-trim: 28 in 1/53 Lambda= 0.130500 statistics sampled from 19847 (19859) to 19847 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.233), width: 16 Scan time: 13.400 The best scores are: opt bits E(85289) NP_055680 (OMIM: 615638) condensin complex subunit (1401) 9101 1725.2 0 XP_011541021 (OMIM: 609276) PREDICTED: condensin-2 (1360) 209 51.1 6.7e-05 NP_056076 (OMIM: 609276) condensin-2 complex subun (1498) 209 51.1 7.2e-05 >>NP_055680 (OMIM: 615638) condensin complex subunit 1 [ (1401 aa) initn: 9101 init1: 9101 opt: 9101 Z-score: 9256.5 bits: 1725.2 E(85289): 0 Smith-Waterman score: 9101; 99.8% identity (99.9% similar) in 1401 aa overlap (1-1401:1-1401) 10 20 30 40 50 60 pF1KA0 MAPQMYEFHLPLSPEELLKSGGVNQYVVQEVLSIKHLPPQLRAFQAAFRAQGPLAMLQHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAPQMYEFHLPLSPEELLKSGGVNQYVVQEVLSIKHLPPQLRAFQAAFRAQGPLAMLQHF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DTIYSILHHFRSIDPGLKEDTLEFLIKVVSRHSQELPAILDDTTLSGSDRNAHLNALKMN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: NP_055 DTIYSILHHFRSIDPGLKEDTLQFLIKVVSRHSQELPAILDDTTLSGSDRNAHLNALKMN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CYALIRLLESFETMASQTNLVDLDLGGKGKKARTKAAHGFDWEEERQPILQLLTQLLQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CYALIRLLESFETMASQTNLVDLDLGGKGKKARTKAAHGFDWEEERQPILQLLTQLLQLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IRHLWNHSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IRHLWNHSIIEEEFVSLVTGCCYRLLENPTINHQKNRPTREAITHLLGVALTRYNHMLSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TVKIIQMLQHFEHLAPVLVAAVSLWATDYGMKSIVGEIVREIGQKCPQELSRDPSGTKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TVKIIQMLQHFEHLAPVLVAAVSLWATDYGMKSIVGEIVREIGQKCPQELSRDPSGTKGF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AAFLTELAERVPAILMSSMCILLDHLDGENYMMRNAVLAAMAEMVLQVLSGDQLEAAARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AAFLTELAERVPAILMSSMCILLDHLDGENYMMRNAVLAAMAEMVLQVLSGDQLEAAARD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TRDQFLDTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TRDQFLDTLQAHGHDVNSFVRSRVLQLFTRIVQQKALPLTRFQAVVALAVGRLADKSVLV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 CKNAIQLLASFLANNPFSCKLSDADLAGPLQKETQKLQEMRAQRRTAAASAVLDPEEEWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CKNAIQLLASFLANNPFSCKLSDADLAGPLQKETQKLQEMRAQRRTAAASAVLDPEEEWE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 AMLPELKSTLQQLLQLPQGEEEIPEQIANTETTEDVKGRIYQLLAKASYKKAIILTREAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AMLPELKSTLQQLLQLPQGEEEIPEQIANTETTEDVKGRIYQLLAKASYKKAIILTREAT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 GHFQESEPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GHFQESEPFSHIDPEESEETRLLNILGLIFKGPAASTQEKNPRESTGNMVTGQTVCKNKP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 NMSDPEESRGNDELVKQEMLVQYLQDAYSFSRKITEAIGIISKMMYENTTTVVQEVIEFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NMSDPEESRGNDELVKQEMLVQYLQDAYSFSRKITEAIGIISKMMYENTTTVVQEVIEFF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 VMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLNAYRQLYLNPKGDSARAKAQALIQNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VMVFQFGVPQALFGVRRMLPLIWSKEPGVREAVLNAYRQLYLNPKGDSARAKAQALIQNL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SLLLVDASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SLLLVDASVGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 MARGKPEIVGSNLDTLVSIGLDEKFPQDYRLAQQVCHAIANISDRRKPSLGKRHPPFRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MARGKPEIVGSNLDTLVSIGLDEKFPQDYRLAQQVCHAIANISDRRKPSLGKRHPPFRLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 QEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLIYQLAEGPEVICAQILQGCAKQALEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QEHRLFERLRETVTKGFVHPDPLWIPFKEVAVTLIYQLAEGPEVICAQILQGCAKQALEK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 LEEKRTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LEEKRTSQEDPKESPAMLPTFLLMNLLSLAGDVALQQLVHLEQAVSGELCRRRVLREEQE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 HKTKDPKEKNTSSETTMEEELGLVGATADDTEAELIRGICEMELLDGKQTLAAFVPLLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HKTKDPKEKNTSSETTMEEELGLVGATADDTEAELIRGICEMELLDGKQTLAAFVPLLLK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 VCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTILEKSPLPIVRSNLMVATG :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: NP_055 VCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTMLEKSPLPIVRSNLMVATG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 DLAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLID 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 PEPQIAALAKNFFNELSHKGNAIYNLLPDIISRLSDPELGVEEEPFHTIMKQLLSYITKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PEPQIAALAKNFFNELSHKGNAIYNLLPDIISRLSDPELGVEEEPFHTIMKQLLSYITKD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 KQTESLVEKLCQRFRTSLTERQQRDLAYCVSQLPLTERGLRKMLDNFDCFGDKLSDESIF ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: NP_055 KQTESLVEKLCQRFRTSRTERQQRDLAYCVSQLPLTERGLRKMLDNFDCFGDKLSDESIF 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SAFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SAFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRGLDGIKELEIGQAGSQRAPSAKKPS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 TGSRYQPLASTASDNDFVTPEPRRTTRRHPNTQQRASKKKPKVVFSSDESSEEDLSAEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TGSRYQPLASTASDNDFVTPEPRRTTRRHPNTQQRASKKKPKVVFSSDESSEEDLSAEMT 1330 1340 1350 1360 1370 1380 1390 1400 pF1KA0 EDETPKKTTPILRASARRHRS ::::::::::::::::::::: NP_055 EDETPKKTTPILRASARRHRS 1390 1400 >>XP_011541021 (OMIM: 609276) PREDICTED: condensin-2 com (1360 aa) initn: 230 init1: 155 opt: 209 Z-score: 209.0 bits: 51.1 E(85289): 6.7e-05 Smith-Waterman score: 209; 22.8% identity (57.4% similar) in 263 aa overlap (1033-1289:781-1038) 1010 1020 1030 1040 1050 1060 pF1KA0 ELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTI . : : ..:::.:. . ... : XP_011 ADHSPSSQGSSEAPASQPPPQVRGSVMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRE 760 770 780 790 800 810 1070 1080 1090 1100 1110 1120 pF1KA0 LEKSPLPIVRSNLMVATGDLAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILK :: ::.:.... :: ::. .:: . :.. :.: .:: . ...:.:. . XP_011 LEVCEDVAVRNNVIIVMCDLCIRYTIMVDKYIPNISMCLKDSDPFIRKQTLILLTNLLQE 820 830 840 850 860 870 1130 1140 1150 1160 1170 pF1KA0 DMVKVKGQVS-EMAVLLIDPEPQIAALAKNFFNELSHKGNAI--YNLLPDIISRLSDPEL ..:: ::.. ... ::: .:.::.... . .: : : . .. . . : .... : XP_011 EFVKWKGSLFFRFVSTLIDSHPDIASFGEFCLAHLLLKRNPVMFFQHFIECIFHFNNYEK 880 890 900 910 920 930 1180 1190 1200 1210 1220 1230 pF1KA0 GVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSLTERQQRDLA--YCVSQLPLTE . . : .. . : :... :. . . .:..:. ... :.: : XP_011 HEKYNKFPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFA 940 950 960 970 980 990 1240 1250 1260 1270 1280 1290 pF1KA0 RGLRKM-LDNFDCFGDKLSDESIFSAFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRG :. . :: . ..: . : . : ..... .: .::. ...: .. : XP_011 DGILPLDLDASELLSDTF--EVLSSKEIKLLA-MR--SKPDKDLLMEEDDMALANVVMQE 1000 1010 1020 1030 1040 1300 1310 1320 1330 1340 1350 pF1KA0 LDGIKELEIGQAGSQRAPSAKKPSTGSRYQPLASTASDNDFVTPEPRRTTRRHPNTQQRA XP_011 AQKKLISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMHYLREVMQDYRDELKDFFA 1050 1060 1070 1080 1090 1100 >>NP_056076 (OMIM: 609276) condensin-2 complex subunit D (1498 aa) initn: 230 init1: 155 opt: 209 Z-score: 208.4 bits: 51.1 E(85289): 7.2e-05 Smith-Waterman score: 209; 22.8% identity (57.4% similar) in 263 aa overlap (1033-1289:919-1176) 1010 1020 1030 1040 1050 1060 pF1KA0 ELLDGKQTLAAFVPLLLKVCNNPGLYSNPDLSAAASLALGKFCMISATFCDSQLRLLFTI . : : ..:::.:. . ... : NP_056 ADHSPSSQGSSEAPASQPPPQVRGSVMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRE 890 900 910 920 930 940 1070 1080 1090 1100 1110 1120 pF1KA0 LEKSPLPIVRSNLMVATGDLAIRFPNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHLILK :: ::.:.... :: ::. .:: . :.. :.: .:: . ...:.:. . NP_056 LEVCEDVAVRNNVIIVMCDLCIRYTIMVDKYIPNISMCLKDSDPFIRKQTLILLTNLLQE 950 960 970 980 990 1000 1130 1140 1150 1160 1170 pF1KA0 DMVKVKGQVS-EMAVLLIDPEPQIAALAKNFFNELSHKGNAI--YNLLPDIISRLSDPEL ..:: ::.. ... ::: .:.::.... . .: : : . .. . . : .... : NP_056 EFVKWKGSLFFRFVSTLIDSHPDIASFGEFCLAHLLLKRNPVMFFQHFIECIFHFNNYEK 1010 1020 1030 1040 1050 1060 1180 1190 1200 1210 1220 1230 pF1KA0 GVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFRTSLTERQQRDLA--YCVSQLPLTE . . : .. . : :... :. . . .:..:. ... :.: : NP_056 HEKYNKFPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFA 1070 1080 1090 1100 1110 1120 1240 1250 1260 1270 1280 1290 pF1KA0 RGLRKM-LDNFDCFGDKLSDESIFSAFLSVVGKLRRGAKPEGKAIIDEFEQKLRACHTRG :. . :: . ..: . : . : ..... .: .::. ...: .. : NP_056 DGILPLDLDASELLSDTF--EVLSSKEIKLLA-MR--SKPDKDLLMEEDDMALANVVMQE 1130 1140 1150 1160 1170 1180 1300 1310 1320 1330 1340 1350 pF1KA0 LDGIKELEIGQAGSQRAPSAKKPSTGSRYQPLASTASDNDFVTPEPRRTTRRHPNTQQRA NP_056 AQKKLISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMHYLREVMQDYRDELKDFFA 1190 1200 1210 1220 1230 1240 1401 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:18:41 2016 done: Wed Nov 2 18:18:42 2016 Total Scan time: 13.400 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]