FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0196, 1159 aa 1>>>pF1KA0196 1159 - 1159 aa - 1159 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0877+/-0.000581; mu= 18.2533+/- 0.036 mean_var=78.3910+/-15.661, 0's: 0 Z-trim(105.2): 44 B-trim: 0 in 0/54 Lambda= 0.144858 statistics sampled from 13432 (13443) to 13432 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.486), E-opt: 0.2 (0.158), width: 16 Scan time: 10.150 The best scores are: opt bits E(85289) XP_016869602 (OMIM: 220210,603563,610657) PREDICTE (1159) 7559 1590.8 0 NP_055661 (OMIM: 220210,603563,610657) WASH comple (1159) 7559 1590.8 0 XP_011515711 (OMIM: 220210,603563,610657) PREDICTE (1095) 6908 1454.7 0 NP_001317538 (OMIM: 220210,603563,610657) WASH com (1011) 6588 1387.8 0 >>XP_016869602 (OMIM: 220210,603563,610657) PREDICTED: W (1159 aa) initn: 7559 init1: 7559 opt: 7559 Z-score: 8532.8 bits: 1590.8 E(85289): 0 Smith-Waterman score: 7559; 100.0% identity (100.0% similar) in 1159 aa overlap (1-1159:1-1159) 10 20 30 40 50 60 pF1KA0 MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPR 1090 1100 1110 1120 1130 1140 1150 pF1KA0 RVAEAHVPNFIFDEFRTVL ::::::::::::::::::: XP_016 RVAEAHVPNFIFDEFRTVL 1150 >>NP_055661 (OMIM: 220210,603563,610657) WASH complex su (1159 aa) initn: 7559 init1: 7559 opt: 7559 Z-score: 8532.8 bits: 1590.8 E(85289): 0 Smith-Waterman score: 7559; 100.0% identity (100.0% similar) in 1159 aa overlap (1-1159:1-1159) 10 20 30 40 50 60 pF1KA0 MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPR 1090 1100 1110 1120 1130 1140 1150 pF1KA0 RVAEAHVPNFIFDEFRTVL ::::::::::::::::::: NP_055 RVAEAHVPNFIFDEFRTVL 1150 >>XP_011515711 (OMIM: 220210,603563,610657) PREDICTED: W (1095 aa) initn: 6908 init1: 6908 opt: 6908 Z-score: 7797.9 bits: 1454.7 E(85289): 0 Smith-Waterman score: 6908; 99.7% identity (99.9% similar) in 1065 aa overlap (1-1065:1-1065) 10 20 30 40 50 60 pF1KA0 MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGL ::::::::::::::::::::::::::::::::::::::::: .:. XP_011 GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGCMCQLCIWNHDGKSNNIVK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPR XP_011 EIRLIFIHEHLILYV 1090 >>NP_001317538 (OMIM: 220210,603563,610657) WASH complex (1011 aa) initn: 6588 init1: 6588 opt: 6588 Z-score: 7437.0 bits: 1387.8 E(85289): 0 Smith-Waterman score: 6588; 100.0% identity (100.0% similar) in 1011 aa overlap (149-1159:1-1011) 120 130 140 150 160 170 pF1KA0 GVYIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSS :::::::::::::::::::::::::::::: NP_001 MLLVIDQKIEGEVRERMLVSYYRYSAARSS 10 20 30 180 190 200 210 220 230 pF1KA0 ADSNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQV 40 50 60 70 80 90 240 250 260 270 280 290 pF1KA0 SAYPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAYPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITV 100 110 120 130 140 150 300 310 320 330 340 350 pF1KA0 NLVDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLVDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDN 160 170 180 190 200 210 360 370 380 390 400 410 pF1KA0 IPKLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPKLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTA 220 230 240 250 260 270 420 430 440 450 460 470 pF1KA0 QFEFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFEFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFRE 280 290 300 310 320 330 480 490 500 510 520 530 pF1KA0 ISKQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISKQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTI 340 350 360 370 380 390 540 550 560 570 580 590 pF1KA0 NIKEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIKEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLL 400 410 420 430 440 450 600 610 620 630 640 650 pF1KA0 RINQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RINQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDK 460 470 480 490 500 510 660 670 680 690 700 710 pF1KA0 DKLRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKLRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRV 520 530 540 550 560 570 720 730 740 750 760 770 pF1KA0 AFALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRII 580 590 600 610 620 630 780 790 800 810 820 830 pF1KA0 NYNVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYNVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTC 640 650 660 670 680 690 840 850 860 870 880 890 pF1KA0 HIDQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIDQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKI 700 710 720 730 740 750 900 910 920 930 940 950 pF1KA0 ILRDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILRDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILR 760 770 780 790 800 810 960 970 980 990 1000 1010 pF1KA0 QQIANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQIANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLE 820 830 840 850 860 870 1020 1030 1040 1050 1060 1070 pF1KA0 AAGIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVL 880 890 900 910 920 930 1080 1090 1100 1110 1120 1130 pF1KA0 GLLTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLLTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKL 940 950 960 970 980 990 1140 1150 pF1KA0 PRRVAEAHVPNFIFDEFRTVL ::::::::::::::::::::: NP_001 PRRVAEAHVPNFIFDEFRTVL 1000 1010 1159 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:31:47 2016 done: Fri Nov 4 00:31:49 2016 Total Scan time: 10.150 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]