FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0197, 1315 aa 1>>>pF1KA0197 1315 - 1315 aa - 1315 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5811+/-0.00051; mu= 21.0861+/- 0.032 mean_var=69.6980+/-14.172, 0's: 0 Z-trim(107.4): 37 B-trim: 377 in 2/50 Lambda= 0.153626 statistics sampled from 15457 (15473) to 15457 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.517), E-opt: 0.2 (0.181), width: 16 Scan time: 12.390 The best scores are: opt bits E(85289) NP_056046 (OMIM: 607614) nuclear pore complex prot (1436) 8637 1924.7 0 NP_001305328 (OMIM: 607614) nuclear pore complex p ( 224) 900 209.6 2.1e-53 >>NP_056046 (OMIM: 607614) nuclear pore complex protein (1436 aa) initn: 8715 init1: 8630 opt: 8637 Z-score: 10335.0 bits: 1924.7 E(85289): 0 Smith-Waterman score: 8637; 99.0% identity (99.2% similar) in 1310 aa overlap (2-1311:37-1341) 10 20 30 pF1KA0 MAAGALERSFVELSGAERERPRHFREFTVCS :::::::::::::::::::::::::::::: NP_056 APPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 IGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 AIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 FTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPY 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 DIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDH 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 KLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 QFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVKYINFEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVKYINFEH 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA0 NVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTERN 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA0 LDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPL 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA0 ALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICL 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA0 IKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIR 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA0 NPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIAST 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA0 RFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATD 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA0 VPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLFSQPKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLFSQPKAP 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA0 LSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNV 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA0 GSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRLQYYDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRLQYYDKV 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA0 LRLLDVIGLPELVIQLATSAITEASDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPD ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_056 LRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPD 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA0 SSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYA 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA0 FHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPV 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA0 SGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAV 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA0 AGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWA 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA0 WLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 WLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLI 1270 1280 1290 1300 1310 1320 1300 1310 pF1KA0 NSHNIALSQKVDKATRDLLYRRTL ::. .::: : :: NP_056 NSY-----KKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPM 1330 1340 1350 1360 1370 1380 >>NP_001305328 (OMIM: 607614) nuclear pore complex prote (224 aa) initn: 900 init1: 900 opt: 900 Z-score: 1079.9 bits: 209.6 E(85289): 2.1e-53 Smith-Waterman score: 900; 100.0% identity (100.0% similar) in 139 aa overlap (2-140:37-175) 10 20 30 pF1KA0 MAAGALERSFVELSGAERERPRHFREFTVCS :::::::::::::::::::::::::::::: NP_001 APPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 IGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 AIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSI ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSVSWLSAISFIS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 FTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPY NP_001 QITLGVTNVVLERCLLELKEIWILVIPHQAYFDSYRLK 190 200 210 220 1315 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:12:51 2016 done: Thu Nov 3 09:12:53 2016 Total Scan time: 12.390 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]