FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0219, 2671 aa 1>>>pF1KA0219 2671 - 2671 aa - 2671 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5981+/-0.00126; mu= 19.3624+/- 0.076 mean_var=81.5354+/-16.075, 0's: 0 Z-trim(100.8): 39 B-trim: 0 in 0/52 Lambda= 0.142037 statistics sampled from 6240 (6253) to 6240 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.527), E-opt: 0.2 (0.192), width: 16 Scan time: 8.750 The best scores are: opt bits E(32554) CCDS41847.1 GCN1 gene_id:10985|Hs108|chr12 (2671) 17080 3511.3 0 >>CCDS41847.1 GCN1 gene_id:10985|Hs108|chr12 (2671 aa) initn: 17080 init1: 17080 opt: 17080 Z-score: 18899.1 bits: 3511.3 E(32554): 0 Smith-Waterman score: 17080; 100.0% identity (100.0% similar) in 2671 aa overlap (1-2671:1-2671) 10 20 30 40 50 60 pF1KA0 MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 YRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 CLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 CLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 YLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDFSQYAMDIV :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS41 YLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDIV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 KGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTME 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 TVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 AHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 TDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQSPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQSPLN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 QSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQLDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQLDR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 EAQVRRRLQELDGELEAALGLLDIILAKNPSGLTQYIPVLVDSFLPLLKSPLAAPRIKNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EAQVRRRLQELDGELEAALGLLDIILAKNPSGLTQYIPVLVDSFLPLLKSPLAAPRIKNP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 FLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 FLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTIT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 SRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 NTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 QEEVDVLLCALQSPCASVRETVLRGLMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QEEVDVLLCALQSPCASVRETVLRGLMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 IRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 IRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 LMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFF 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 VPDALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VPDALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQR 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 LMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 SLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQ 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 ALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 QRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 LGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIV 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 ATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 GQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLR 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 EILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDER 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 QGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LEDILPFLLKQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LEDILPFLLKQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSV 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 AGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEAT 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 RSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAIT 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 KKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQK 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 EEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIA 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 LKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGV 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KA0 RDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEE 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KA0 ELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATAD 2470 2480 2490 2500 2510 2520 2530 2540 2550 2560 2570 2580 pF1KA0 RIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKD 2530 2540 2550 2560 2570 2580 2590 2600 2610 2620 2630 2640 pF1KA0 PLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVAS 2590 2600 2610 2620 2630 2640 2650 2660 2670 pF1KA0 LEVLNEVNRRSLKKLASQADSTEQVDDTILT ::::::::::::::::::::::::::::::: CCDS41 LEVLNEVNRRSLKKLASQADSTEQVDDTILT 2650 2660 2670 2671 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:46:46 2016 done: Sat Nov 5 20:46:48 2016 Total Scan time: 8.750 Total Display time: 0.360 Function used was FASTA [36.3.4 Apr, 2011]