Result of FASTA (omim) for
pF1KA0219
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0219, 2671 aa
1>>>pF1KA0219 2671 - 2671 aa - 2671 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4933+/-0.000536; mu= 26.3026+/- 0.033
mean_var=91.9338+/-19.072, 0's: 0 Z-trim(108.2): 76 B-trim: 839 in 2/52
Lambda= 0.133763
statistics sampled from 16234 (16281) to 16234 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.518), E-opt: 0.2 (0.191), width: 16
Scan time: 22.600
The best scores are: opt bits E(85289)
NP_006827 (OMIM: 605614) eIF-2-alpha kinase activa (2671) 17080 3308.6 0
NP_055040 (OMIM: 605983,616362) serine/threonine-p ( 589) 193 49.2 0.00021
XP_016882418 (OMIM: 605983,616362) PREDICTED: seri ( 410) 186 47.7 0.0004
>>NP_006827 (OMIM: 605614) eIF-2-alpha kinase activator (2671 aa)
initn: 17080 init1: 17080 opt: 17080 Z-score: 17803.8 bits: 3308.6 E(85289): 0
Smith-Waterman score: 17080; 100.0% identity (100.0% similar) in 2671 aa overlap (1-2671:1-2671)
10 20 30 40 50 60
pF1KA0 MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 YRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 CLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDFSQYAMDIV
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_006 YLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDIV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 KGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 VPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 TQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 TDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQSPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQSPLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SAQQDSIKKANMKRENKAYSFKEQIIELELKEEIKKKKGIKEEVQLTSKQKEMLQAQLDR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EAQVRRRLQELDGELEAALGLLDIILAKNPSGLTQYIPVLVDSFLPLLKSPLAAPRIKNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EAQVRRRLQELDGELEAALGLLDIILAKNPSGLTQYIPVLVDSFLPLLKSPLAAPRIKNP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 FLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTIT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 SRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 NTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 QEEVDVLLCALQSPCASVRETVLRGLMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QEEVDVLLCALQSPCASVRETVLRGLMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 IRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 LMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LMEIYQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFF
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 VPDALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VPDALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 VLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 LMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 AFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 SLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 ALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 QRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 LGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIV
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 ATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRA
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 GQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 DDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLR
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 EILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDER
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 QGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 LEDILPFLLKQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LEDILPFLLKQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSV
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 AGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEAT
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 RSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAIT
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA0 KKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQK
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KA0 EEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIA
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KA0 LKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LKPFLPQLQTTFTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGV
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KA0 RDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEE
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KA0 ELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATAD
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KA0 RIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKD
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KA0 PLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVAS
2590 2600 2610 2620 2630 2640
2650 2660 2670
pF1KA0 LEVLNEVNRRSLKKLASQADSTEQVDDTILT
:::::::::::::::::::::::::::::::
NP_006 LEVLNEVNRRSLKKLASQADSTEQVDDTILT
2650 2660 2670
>>NP_055040 (OMIM: 605983,616362) serine/threonine-prote (589 aa)
initn: 100 init1: 64 opt: 193 Z-score: 200.2 bits: 49.2 E(85289): 0.00021
Smith-Waterman score: 243; 21.5% identity (53.9% similar) in 627 aa overlap (1366-1978:1-574)
1340 1350 1360 1370 1380 1390
pF1KA0 KVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQRLMQQLLESDKYAERK
.. : .:. : :...: . : :
NP_055 MAAADGDDSLYPIAVLIDELRNED-VQLRL
10 20
1400 1410 1420 1430 1440 1450
pF1KA0 GAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAF-EMLCTMLGKLFE
.. :. .. .::. .. :.. :::.: :. . .:.:. :.: :. .
NP_055 NSIKKLSTIALALGVERTRS-ELLPFLTDTIYDEDE------VLLALAEQLGTFTTLVGG
30 40 50 60 70 80
1460 1470 1480 1490 1500 1510
pF1KA0 PYVVH-VLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRT
: :: .:: : . ::. : . .:. . : .. . :. : .: :
NP_055 PEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFT
90 100 110 120 130 140
1520 1530 1540 1550 1560 1570
pF1KA0 KAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPE
. :. : .. : :. :. .. . .. .:. :..:. . : ....:.. .
NP_055 SRTSA--CGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDN
150 160 170 180 190 200
1580 1590 1600 1610 1620 1630
pF1KA0 ILA-IAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSL-ALIMPIVQRAFQDRSTDT
. . : : ... :.. . . . : . ....... .: ::.:: ...: .:.: .
NP_055 VKSEIIP-MFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRV
210 220 230 240 250
1640 1650 1660 1670 1680
pF1KA0 RKMAAQIIGNMYSLTDQKDLAPYLPS--VTPGLKASLLDPVPEVRTVSAKALGAMVKGMG
: :.:. . .. :: ..: . . ..:... . : :::..... . . ....
NP_055 RYMVADKFTEL-----QKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLS
260 270 280 290 300 310
1690 1700 1710 1720 1730 1740
pF1KA0 ESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGL----GVEK-LEKLMPEIVATAS
.: :... . : : . . ..:: :. :: : .. .:.:.: ..: .
NP_055 ADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLK
320 330 340 350 360 370
1750 1760 1770 1780 1790 1800
pF1KA0 KVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRV
: :.:: . : .. . ..: . ..: :. :...:. :. .
NP_055 --DECPEVRLNIISNLDCVNEVIGIR--QLSQSLLPAIV-------ELAEDAKWRVRLAI
380 390 400 410 420
1810 1820 1830 1840 1850 1860
pF1KA0 ISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNF
: . . :: :: .::. ...:. .. :. :. .. :.. . ..:
NP_055 IEY-----MPLLAGQLGVEFFDE----KLNSL-CMAWLVDHVYAIREAATSNLKKLVEKF
430 440 450 460 470
1870 1880 1890 1900 1910 1920
pF1KA0 GTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIV--VSNTPRTLREI
: .. .:: .::: :. .: . . :...: ... : . : ...
NP_055 GKEWAHATIIP--------KVLA---MS-GDPNYLHRMTTLFCINVLSEVCGQDITTKHM
480 490 500 510 520
1930 1940 1950 1960 1970 1980
pF1KA0 LPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILP-EIIPILEEGLRSQKSDERQ
::: .: . .. :. : .:..: . : .. : :. ::::. ..: :
NP_055 LPT----VLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKY
530 540 550 560 570
1990 2000 2010 2020 2030 2040
pF1KA0 GVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQAL
NP_055 FAQEALTVLSLA
580
>>XP_016882418 (OMIM: 605983,616362) PREDICTED: serine/t (410 aa)
initn: 132 init1: 64 opt: 186 Z-score: 195.0 bits: 47.7 E(85289): 0.0004
Smith-Waterman score: 186; 22.8% identity (52.2% similar) in 381 aa overlap (1616-1978:26-395)
1590 1600 1610 1620 1630 1640
pF1KA0 TDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSL
:.:. . .:.. ..: .:.. :. .:
XP_016 MVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQL
10 20 30 40 50
1650 1660 1670 1680 1690 1700
pF1KA0 TDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMG-ESCFEDLLPWLMETL
:.:: : : :. . : .:: . : . . :..: : ::.: ... .
XP_016 LPQEDLEAL---VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLM
60 70 80 90 100 110
1710 1720 1730 1740 1750 1760
pF1KA0 TYEQSSVDRSGAAQGLAEVMAGLGVEKLEK-LMPEIVATASKV--DIAPHVRDGYIMMFN
.. : :..:.. . : .:... :. .: .:. ... : ::... ..
XP_016 KDCEAEV-RAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIM
120 130 140 150 160 170
1770 1780 1790 1800 1810 1820
pF1KA0 YLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIAL-LLPQL
: .: : . ..: .: : :: :: . . . : . . .. ::: .
XP_016 GLSPILGKDNT--IEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAI
180 190 200 210 220
1830 1840 1850 1860 1870
pF1KA0 EQGLFDDLWRIRFSSVQLLGDLLFHISGVT---GKMTTETASE--DDNFG---TAQSN-K
. : ::.:.. .. . :: :: :... . : .. .: :: :
XP_016 VELAEDAKWRVRLAIIEYM-PLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLK
230 240 250 260 270 280
1880 1890 1900 1910 1920
pF1KA0 AIITALGVERRNRVLAGLYMGRS-DTQLVVRQASLHVWKIV--VSNTPRTLREILPTLFG
.. .: : . .. .. : : . . :...: ... : . : ...:::.
XP_016 KLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTV--
290 300 310 320 330 340
1930 1940 1950 1960 1970 1980
pF1KA0 LLLGFLASTCADKRTIAARTLGDLVRKLGEKILP-EIIPILEEGLRSQKSDERQGVCIGL
: . .. :. : .:..: . : .. : :. ::::. ..: :
XP_016 --LRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL
350 360 370 380 390 400
1990 2000 2010 2020 2030 2040
pF1KA0 SEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPF
XP_016 TVLSLA
410
2671 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:46:48 2016 done: Sat Nov 5 20:46:52 2016
Total Scan time: 22.600 Total Display time: 0.380
Function used was FASTA [36.3.4 Apr, 2011]