FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0227, 222 aa 1>>>pF1KA0227 222 - 222 aa - 222 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9876+/-0.000662; mu= 9.3333+/- 0.040 mean_var=148.9207+/-30.137, 0's: 0 Z-trim(116.4): 8 B-trim: 0 in 0/53 Lambda= 0.105099 statistics sampled from 17046 (17053) to 17046 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.818), E-opt: 0.2 (0.524), width: 16 Scan time: 2.260 The best scores are: opt bits E(32554) CCDS45132.1 TTC9 gene_id:23508|Hs108|chr14 ( 222) 1484 235.2 2.5e-62 CCDS12550.1 TTC9B gene_id:148014|Hs108|chr19 ( 239) 726 120.3 1e-27 CCDS8033.1 TTC9C gene_id:283237|Hs108|chr11 ( 171) 498 85.6 2.1e-17 >>CCDS45132.1 TTC9 gene_id:23508|Hs108|chr14 (222 aa) initn: 1484 init1: 1484 opt: 1484 Z-score: 1232.5 bits: 235.2 E(32554): 2.5e-62 Smith-Waterman score: 1484; 99.5% identity (99.5% similar) in 222 aa overlap (1-222:1-222) 10 20 30 40 50 60 pF1KA0 MERKGSAAGAKGNPSPPAAGEGQRPPPPLCVPGGGGGAPARGQVGAAAEPAELIRRAHEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MERKGSAAGAKGNPSPPAAGEGQRPPPPLCVPGGGGGAPARGQVGAAAEPAELIRRAHEF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KSQGAQCYKDKKFREAIGKYHRALLELKGLLPPPGERERDSRAASPAGALKPGRLSEEQS :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS45 KSQGAQCYKDKKFREAIGKYHRALLELKGLLPPPGERERDSRPASPAGALKPGRLSEEQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDY 130 140 150 160 170 180 190 200 210 220 pF1KA0 DKALYYLKEARTQQPTDTNVIRYIQLTEMKLSRCSQREKEAM :::::::::::::::::::::::::::::::::::::::::: CCDS45 DKALYYLKEARTQQPTDTNVIRYIQLTEMKLSRCSQREKEAM 190 200 210 220 >>CCDS12550.1 TTC9B gene_id:148014|Hs108|chr19 (239 aa) initn: 794 init1: 535 opt: 726 Z-score: 611.0 bits: 120.3 E(32554): 1e-27 Smith-Waterman score: 751; 55.2% identity (73.8% similar) in 221 aa overlap (14-218:16-226) 10 20 30 40 pF1KA0 MERKGSAAGAKGNPSPPAAGEGQRPPPPLCVPGGGGGAPAR-------------GQVG : :: :::: : ::.: :. .: :..: CCDS12 MQRGALSPVLMLSAAPEPPP-----RPPPALSPPGSGPGSGSRHGSARPGPTPEPSGSLG 10 20 30 40 50 50 60 70 80 90 100 pF1KA0 AAAEPAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPPPGERERDSRAAS :: . . .: : ::..: .::..:::::::::::::::.::. : : : . CCDS12 AALDSS--LRAAVAFKAEGQRCYREKKFREAIGKYHRALLQLKA---AQGARPSGLPAPA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KA0 PAGALKPG--RLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGEN :. . .:: :::::: . ::. :..::.::.:::::.::::::::.:::::::.:. : CCDS12 PGPTSSPGPARLSEEQRRLVESTEVECYDSLTACLLQSELVNYERVREYCLKVLEKQQGN 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 FKALYRSGVAFYHLGDYDKALYYLKEARTQQPTDTNVIRYIQLTEMKLSRCS-QREKEAM ::: ::.:.:::::::: .:: ::.:::...::::::.::::::..:..::: ::: CCDS12 FKATYRAGIAFYHLGDYARALRYLQEARSREPTDTNVLRYIQLTQLKMNRCSLQREDSGA 180 190 200 210 220 230 CCDS12 GSQTRDVIG >>CCDS8033.1 TTC9C gene_id:283237|Hs108|chr11 (171 aa) initn: 510 init1: 386 opt: 498 Z-score: 426.0 bits: 85.6 E(32554): 2.1e-17 Smith-Waterman score: 498; 47.9% identity (71.6% similar) in 169 aa overlap (54-220:5-164) 30 40 50 60 70 80 pF1KA0 RPPPPLCVPGGGGGAPARGQVGAAAEPAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRA ...:. .: .: : :.. :.:.:...:::: CCDS80 MEKRLQEAQLYKEEGNQRYREGKYRDAVSRYHRA 10 20 30 90 100 110 120 130 140 pF1KA0 LLELKGLLPPPGERERDSRAASPAGALKPG--RLSEEQSKTVEAIEIDCYNSLAACLLQA ::.:.:: : :: : : :. :: . ... . ::::.::::::: CCDS80 LLQLRGL---------DPSLPSPLPNLGPQGPALTPEQENILHTTQTDCYNNLAACLLQM 40 50 60 70 80 150 160 170 180 190 200 pF1KA0 ELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTQQPTDTNVI : ::::::.:: :::... .: :::::.::::.:: :::.: .:: : ..:: :.:: CCDS80 EPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDQARHYLLAAVNRQPKDANVR 90 100 110 120 130 140 210 220 pF1KA0 RYIQLTEMKLSRCSQREKEAM ::.:::. .:: ..::. CCDS80 RYLQLTQSELSSYHRKEKQLYLGMFG 150 160 170 222 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:33:25 2016 done: Fri Nov 4 00:33:25 2016 Total Scan time: 2.260 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]