FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0228, 585 aa 1>>>pF1KA0228 585 - 585 aa - 585 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7814+/-0.000545; mu= 16.4698+/- 0.034 mean_var=76.2345+/-14.963, 0's: 0 Z-trim(107.0): 101 B-trim: 112 in 1/50 Lambda= 0.146892 statistics sampled from 15079 (15106) to 15079 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.522), E-opt: 0.2 (0.177), width: 16 Scan time: 10.030 The best scores are: opt bits E(85289) NP_006371 (OMIM: 605324) amyloid protein-binding p ( 585) 3863 829.1 0 NP_001269405 (OMIM: 605324) amyloid protein-bindin ( 514) 3372 725.0 1.5e-208 XP_011522500 (OMIM: 605324) PREDICTED: amyloid pro ( 499) 3287 707.0 3.8e-203 XP_011522501 (OMIM: 605324) PREDICTED: amyloid pro ( 393) 2558 552.4 9.9e-157 NP_803136 (OMIM: 601334) kinesin light chain 3 [Ho ( 504) 188 50.2 1.9e-05 XP_016873622 (OMIM: 609541,611729) PREDICTED: kine ( 425) 161 44.5 0.00087 NP_001128246 (OMIM: 609541,611729) kinesin light c ( 545) 161 44.5 0.0011 XP_005274241 (OMIM: 609541,611729) PREDICTED: kine ( 600) 161 44.5 0.0012 NP_073733 (OMIM: 609541,611729) kinesin light chai ( 622) 161 44.6 0.0012 XP_005274240 (OMIM: 609541,611729) PREDICTED: kine ( 622) 161 44.6 0.0012 NP_001305663 (OMIM: 609541,611729) kinesin light c ( 622) 161 44.6 0.0012 NP_001128248 (OMIM: 609541,611729) kinesin light c ( 622) 161 44.6 0.0012 NP_001128247 (OMIM: 609541,611729) kinesin light c ( 622) 161 44.6 0.0012 NP_694972 (OMIM: 208540,267010,604387,608002) neph (1330) 164 45.4 0.0015 NP_005543 (OMIM: 600025) kinesin light chain 1 iso ( 560) 151 42.4 0.0048 NP_891553 (OMIM: 600025) kinesin light chain 1 iso ( 573) 151 42.4 0.0049 NP_001123579 (OMIM: 600025) kinesin light chain 1 ( 618) 151 42.4 0.0052 >>NP_006371 (OMIM: 605324) amyloid protein-binding prote (585 aa) initn: 3863 init1: 3863 opt: 3863 Z-score: 4426.8 bits: 829.1 E(85289): 0 Smith-Waterman score: 3863; 100.0% identity (100.0% similar) in 585 aa overlap (1-585:1-585) 10 20 30 40 50 60 pF1KA0 MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 CELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 FGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 YNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVL 490 500 510 520 530 540 550 560 570 580 pF1KA0 SNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC ::::::::::::::::::::::::::::::::::::::::::::: NP_006 SNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC 550 560 570 580 >>NP_001269405 (OMIM: 605324) amyloid protein-binding pr (514 aa) initn: 3372 init1: 3372 opt: 3372 Z-score: 3865.3 bits: 725.0 E(85289): 1.5e-208 Smith-Waterman score: 3372; 100.0% identity (100.0% similar) in 510 aa overlap (76-585:5-514) 50 60 70 80 90 100 pF1KA0 KLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRC :::::::::::::::::::::::::::::: NP_001 MFTTRHLLHHCFQALMDHGVKVASVLAYSFSRRC 10 20 30 110 120 130 140 150 160 pF1KA0 SYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVEC 40 50 60 70 80 90 170 180 190 200 210 220 pF1KA0 CVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEA 100 110 120 130 140 150 230 240 250 260 270 280 pF1KA0 YKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHP 160 170 180 190 200 210 290 300 310 320 330 340 pF1KA0 KYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQY 220 230 240 250 260 270 350 360 370 380 390 400 pF1KA0 SSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQE 280 290 300 310 320 330 410 420 430 440 450 460 pF1KA0 AHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQ 340 350 360 370 380 390 470 480 490 500 510 520 pF1KA0 EDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYN 400 410 420 430 440 450 530 540 550 560 570 580 pF1KA0 SIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC 460 470 480 490 500 510 >>XP_011522500 (OMIM: 605324) PREDICTED: amyloid protein (499 aa) initn: 3287 init1: 3287 opt: 3287 Z-score: 3768.1 bits: 707.0 E(85289): 3.8e-203 Smith-Waterman score: 3287; 100.0% identity (100.0% similar) in 499 aa overlap (87-585:1-499) 60 70 80 90 100 110 pF1KA0 GSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVK :::::::::::::::::::::::::::::: XP_011 MDHGVKVASVLAYSFSRRCSYIAESDAAVK 10 20 30 120 130 140 150 160 170 pF1KA0 EKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGN 40 50 60 70 80 90 180 190 200 210 220 230 pF1KA0 CKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEI 100 110 120 130 140 150 240 250 260 270 280 290 pF1KA0 TAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGF 160 170 180 190 200 210 300 310 320 330 340 350 pF1KA0 YLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFH 220 230 240 250 260 270 360 370 380 390 400 410 pF1KA0 AERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQL 280 290 300 310 320 330 420 430 440 450 460 470 pF1KA0 AKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGH 340 350 360 370 380 390 480 490 500 510 520 530 pF1KA0 LASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEY 400 410 420 430 440 450 540 550 560 570 580 pF1KA0 HNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC 460 470 480 490 >>XP_011522501 (OMIM: 605324) PREDICTED: amyloid protein (393 aa) initn: 2558 init1: 2558 opt: 2558 Z-score: 2934.8 bits: 552.4 E(85289): 9.9e-157 Smith-Waterman score: 2558; 100.0% identity (100.0% similar) in 393 aa overlap (193-585:1-393) 170 180 190 200 210 220 pF1KA0 VECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHY :::::::::::::::::::::::::::::: XP_011 MDKLSKHGQQANKAALYGELCALLFAKSHY 10 20 30 230 240 250 260 270 280 pF1KA0 DEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGS 40 50 60 70 80 90 290 300 310 320 330 340 pF1KA0 KHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYV 100 110 120 130 140 150 350 360 370 380 390 400 pF1KA0 HQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRL 160 170 180 190 200 210 410 420 430 440 450 460 pF1KA0 LQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQL 220 230 240 250 260 270 470 480 490 500 510 520 pF1KA0 LGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIK 280 290 300 310 320 330 530 540 550 560 570 580 pF1KA0 LYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEG 340 350 360 370 380 390 pF1KA0 PSC ::: XP_011 PSC >>NP_803136 (OMIM: 601334) kinesin light chain 3 [Homo s (504 aa) initn: 339 init1: 135 opt: 188 Z-score: 218.7 bits: 50.2 E(85289): 1.9e-05 Smith-Waterman score: 188; 27.3% identity (65.7% similar) in 143 aa overlap (399-540:261-402) 370 380 390 400 410 420 pF1KA0 PEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQT .: .:: :: ..::. ....: . . NP_803 RQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAV 240 250 260 270 280 290 430 440 450 460 470 480 pF1KA0 AKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQY : .::. :: . ...::: . .:..:.:..:: . .:: ....:: : ..... NP_803 AATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLA-LLCQNQGKF 300 310 320 330 340 490 500 510 520 530 540 pF1KA0 ENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFE-YHNVLSNWNRLR :..:. : :...: . : : .. .: . : . ..:... : :...: NP_803 EDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPA 350 360 370 380 390 400 550 560 570 580 pF1KA0 DRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC NP_803 PLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRGEAAAGAAGMKRAMSLNT 410 420 430 440 450 460 >>XP_016873622 (OMIM: 609541,611729) PREDICTED: kinesin (425 aa) initn: 137 init1: 137 opt: 161 Z-score: 189.0 bits: 44.5 E(85289): 0.00087 Smith-Waterman score: 181; 28.4% identity (63.9% similar) in 169 aa overlap (340-507:49-205) 310 320 330 340 350 360 pF1KA0 IYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILP : .: ...:. .: . :..: . : XP_016 APQPIVRKLPTALGAWRAGAEQVSPHSGSHSVIHTQDQNKYKEAAHLLNDALAIREKTLG 20 30 40 50 60 70 370 380 390 400 410 420 pF1KA0 EDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTA .:: .:.. :...:. ..:. . . ::. : .:.. .:..:.:. ..: XP_016 KDHPAVAAT-------LNNLAV-LYGKRGKYK---EAEPLCKRALEIREKVLGKFHPDVA 80 90 100 110 120 430 440 450 460 470 480 pF1KA0 KHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYE :. .::. : :.. : .:.: .. .:..: :: .: .:: . ..::: : ...:. XP_016 KQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCY-LKQGKYQ 130 140 150 160 170 180 490 500 510 520 530 540 pF1KA0 NAEKLYLRSIA-IGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRD .:: :: . .. .: :: XP_016 DAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKV 190 200 210 220 230 240 >>NP_001128246 (OMIM: 609541,611729) kinesin light chain (545 aa) initn: 178 init1: 137 opt: 161 Z-score: 187.3 bits: 44.5 E(85289): 0.0011 Smith-Waterman score: 176; 26.2% identity (58.9% similar) in 202 aa overlap (342-541:128-317) 320 330 340 350 360 370 pF1KA0 QAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSS-GKFDNALFHAERAIGIITHILPE : ::.: :... :. ..:. . . . NP_001 SPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGH 100 110 120 130 140 150 380 390 400 410 420 430 pF1KA0 DHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAK :: .:. . ::. .. .:: : :: :. ..: . .:..:. . .: NP_001 DHPDVATMLNILALVYRD-----QNKYKE-----AAHLLN-DALAIREKTLGKDHPAVAA 160 170 180 190 200 440 450 460 470 480 490 pF1KA0 HYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYEN .::. :: . :.:::: . .:..:.:..::. .:: ....:: : .... :. NP_001 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA-LLCQNQGKAEE 210 220 230 240 250 260 500 510 520 530 540 pF1KA0 AEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFE-YHNVLSNWNRLRDR .: : :.. : .: .. .: . : . :.:. . :...:. NP_001 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFG 270 280 290 300 310 320 550 560 570 580 pF1KA0 QYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC NP_001 SVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQ 330 340 350 360 370 380 >>XP_005274241 (OMIM: 609541,611729) PREDICTED: kinesin (600 aa) initn: 178 init1: 137 opt: 161 Z-score: 186.7 bits: 44.5 E(85289): 0.0012 Smith-Waterman score: 176; 26.2% identity (58.9% similar) in 202 aa overlap (342-541:205-394) 320 330 340 350 360 370 pF1KA0 QAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSS-GKFDNALFHAERAIGIITHILPE : ::.: :... :. ..:. . . . XP_005 SPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGH 180 190 200 210 220 230 380 390 400 410 420 430 pF1KA0 DHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAK :: .:. . ::. .. .:: : :: :. ..: . .:..:. . .: XP_005 DHPDVATMLNILALVYRD-----QNKYKE-----AAHLLN-DALAIREKTLGKDHPAVAA 240 250 260 270 280 440 450 460 470 480 490 pF1KA0 HYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYEN .::. :: . :.:::: . .:..:.:..::. .:: ....:: : .... :. XP_005 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA-LLCQNQGKAEE 290 300 310 320 330 340 500 510 520 530 540 pF1KA0 AEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFE-YHNVLSNWNRLRDR .: : :.. : .: .. .: . : . :.:. . :...:. XP_005 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFG 350 360 370 380 390 400 550 560 570 580 pF1KA0 QYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC XP_005 SVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQ 410 420 430 440 450 460 >>NP_073733 (OMIM: 609541,611729) kinesin light chain 2 (622 aa) initn: 178 init1: 137 opt: 161 Z-score: 186.4 bits: 44.6 E(85289): 0.0012 Smith-Waterman score: 176; 26.2% identity (58.9% similar) in 202 aa overlap (342-541:205-394) 320 330 340 350 360 370 pF1KA0 QAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSS-GKFDNALFHAERAIGIITHILPE : ::.: :... :. ..:. . . . NP_073 SPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGH 180 190 200 210 220 230 380 390 400 410 420 430 pF1KA0 DHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAK :: .:. . ::. .. .:: : :: :. ..: . .:..:. . .: NP_073 DHPDVATMLNILALVYRD-----QNKYKE-----AAHLLN-DALAIREKTLGKDHPAVAA 240 250 260 270 280 440 450 460 470 480 490 pF1KA0 HYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYEN .::. :: . :.:::: . .:..:.:..::. .:: ....:: : .... :. NP_073 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA-LLCQNQGKAEE 290 300 310 320 330 340 500 510 520 530 540 pF1KA0 AEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFE-YHNVLSNWNRLRDR .: : :.. : .: .. .: . : . :.:. . :...:. NP_073 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFG 350 360 370 380 390 400 550 560 570 580 pF1KA0 QYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC NP_073 SVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQ 410 420 430 440 450 460 >>XP_005274240 (OMIM: 609541,611729) PREDICTED: kinesin (622 aa) initn: 178 init1: 137 opt: 161 Z-score: 186.4 bits: 44.6 E(85289): 0.0012 Smith-Waterman score: 176; 26.2% identity (58.9% similar) in 202 aa overlap (342-541:205-394) 320 330 340 350 360 370 pF1KA0 QAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSS-GKFDNALFHAERAIGIITHILPE : ::.: :... :. ..:. . . . XP_005 SPAPSPGGGDVSGQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGH 180 190 200 210 220 230 380 390 400 410 420 430 pF1KA0 DHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAK :: .:. . ::. .. .:: : :: :. ..: . .:..:. . .: XP_005 DHPDVATMLNILALVYRD-----QNKYKE-----AAHLLN-DALAIREKTLGKDHPAVAA 240 250 260 270 280 440 450 460 470 480 490 pF1KA0 HYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYEN .::. :: . :.:::: . .:..:.:..::. .:: ....:: : .... :. XP_005 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLA-LLCQNQGKAEE 290 300 310 320 330 340 500 510 520 530 540 pF1KA0 AEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFE-YHNVLSNWNRLRDR .: : :.. : .: .. .: . : . :.:. . :...:. XP_005 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFG 350 360 370 380 390 400 550 560 570 580 pF1KA0 QYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC XP_005 SVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQ 410 420 430 440 450 460 585 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:58:21 2016 done: Sat Nov 5 21:58:22 2016 Total Scan time: 10.030 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]