Result of FASTA (omim) for
pF1KA0229
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0229, 1134 aa
1>>>pF1KA0229 1134 - 1134 aa - 1134 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2555+/-0.00049; mu= 0.3542+/- 0.031
mean_var=376.0598+/-77.794, 0's: 0 Z-trim(120.9): 490 B-trim: 977 in 1/53
Lambda= 0.066137
statistics sampled from 36253 (36868) to 36253 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.432), width: 16
Scan time: 18.680
The best scores are: opt bits E(85289)
NP_056060 (OMIM: 608994) ankyrin repeat and SAM do (1134) 7530 733.9 1.3e-210
XP_011512737 (OMIM: 608994) PREDICTED: ankyrin rep (1144) 7530 733.9 1.3e-210
XP_011512736 (OMIM: 608994) PREDICTED: ankyrin rep (1145) 7518 732.8 2.9e-210
XP_005249021 (OMIM: 608994) PREDICTED: ankyrin rep (1155) 6576 642.9 3.3e-183
XP_011512734 (OMIM: 608994) PREDICTED: ankyrin rep (1165) 6576 642.9 3.3e-183
XP_011512738 (OMIM: 608994) PREDICTED: ankyrin rep (1100) 6564 641.7 7.1e-183
XP_006715099 (OMIM: 608994) PREDICTED: ankyrin rep (1156) 6564 641.7 7.3e-183
XP_011512733 (OMIM: 608994) PREDICTED: ankyrin rep (1166) 6564 641.7 7.4e-183
XP_011512735 (OMIM: 608994) PREDICTED: ankyrin rep (1162) 6557 641.1 1.2e-182
XP_016866082 (OMIM: 608994) PREDICTED: ankyrin rep ( 593) 3916 388.8 5.3e-107
XP_011512739 (OMIM: 608994) PREDICTED: ankyrin rep ( 604) 3904 387.6 1.2e-106
XP_016875152 (OMIM: 607815) PREDICTED: ankyrin rep ( 476) 1605 168.2 1.1e-40
XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 1377 146.8 7.2e-34
XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 1377 146.8 7.2e-34
XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 1377 146.8 7.3e-34
XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 1377 146.8 7.3e-34
XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 1377 146.8 7.4e-34
XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235) 1377 146.8 7.4e-34
NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248) 1377 146.9 7.5e-34
XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 1377 146.9 7.5e-34
XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 1377 146.9 7.5e-34
XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 1377 146.9 7.5e-34
XP_016875144 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 1377 146.9 7.5e-34
XP_006719572 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 1377 146.9 7.5e-34
XP_005269085 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 1377 146.9 7.5e-34
XP_006719571 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 1377 146.9 7.5e-34
XP_016875143 (OMIM: 607815) PREDICTED: ankyrin rep (1268) 1377 146.9 7.6e-34
XP_016875142 (OMIM: 607815) PREDICTED: ankyrin rep (1272) 1377 146.9 7.6e-34
XP_006719570 (OMIM: 607815) PREDICTED: ankyrin rep (1273) 1377 146.9 7.6e-34
XP_016875141 (OMIM: 607815) PREDICTED: ankyrin rep (1281) 1377 146.9 7.6e-34
XP_006719569 (OMIM: 607815) PREDICTED: ankyrin rep (1283) 1377 146.9 7.6e-34
XP_006719568 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 1377 146.9 7.6e-34
XP_006719567 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 1377 146.9 7.6e-34
XP_016875140 (OMIM: 607815) PREDICTED: ankyrin rep (1285) 1377 146.9 7.6e-34
XP_016875153 (OMIM: 607815) PREDICTED: ankyrin rep ( 429) 1100 119.9 3.3e-26
XP_016875149 (OMIM: 607815) PREDICTED: ankyrin rep ( 486) 1089 118.9 7.4e-26
NP_001191009 (OMIM: 607815) ankyrin repeat and ste ( 266) 1057 115.6 4.1e-25
XP_005269089 (OMIM: 607815) PREDICTED: ankyrin rep ( 266) 1057 115.6 4.1e-25
NP_001190997 (OMIM: 607815) ankyrin repeat and ste ( 460) 1037 113.9 2.2e-24
NP_001191008 (OMIM: 607815) ankyrin repeat and ste ( 290) 1026 112.7 3.4e-24
NP_001190995 (OMIM: 607815) ankyrin repeat and ste ( 357) 1026 112.8 3.9e-24
NP_001190994 (OMIM: 607815) ankyrin repeat and ste ( 290) 1017 111.8 6.1e-24
NP_001191010 (OMIM: 607815) ankyrin repeat and ste ( 254) 1005 110.6 1.2e-23
XP_016875148 (OMIM: 607815) PREDICTED: ankyrin rep ( 511) 717 83.5 3.7e-15
NP_858056 (OMIM: 607815) ankyrin repeat and steril ( 510) 715 83.3 4.2e-15
XP_016875151 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 713 83.1 4.6e-15
XP_016875150 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 711 82.9 5.3e-15
NP_065804 (OMIM: 612185) caskin-2 isoform a [Homo (1202) 672 79.6 1.3e-13
NP_064525 (OMIM: 607815) ankyrin repeat and steril ( 414) 658 77.7 1.6e-13
XP_016875154 (OMIM: 607815) PREDICTED: ankyrin rep ( 425) 658 77.7 1.6e-13
>>NP_056060 (OMIM: 608994) ankyrin repeat and SAM domain (1134 aa)
initn: 7530 init1: 7530 opt: 7530 Z-score: 3902.2 bits: 733.9 E(85289): 1.3e-210
Smith-Waterman score: 7530; 99.9% identity (99.9% similar) in 1134 aa overlap (1-1134:1-1134)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 YEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLN
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_056 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 TQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KA0 MIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
1090 1100 1110 1120 1130
>>XP_011512737 (OMIM: 608994) PREDICTED: ankyrin repeat (1144 aa)
initn: 7530 init1: 7530 opt: 7530 Z-score: 3902.1 bits: 733.9 E(85289): 1.3e-210
Smith-Waterman score: 7530; 99.9% identity (99.9% similar) in 1134 aa overlap (1-1134:1-1134)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 YEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLN
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 TQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KA0 MIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTNFHWISY
1090 1100 1110 1120 1130 1140
XP_011 WSKI
>>XP_011512736 (OMIM: 608994) PREDICTED: ankyrin repeat (1145 aa)
initn: 6896 init1: 6641 opt: 7518 Z-score: 3895.9 bits: 732.8 E(85289): 2.9e-210
Smith-Waterman score: 7518; 99.8% identity (99.8% similar) in 1135 aa overlap (1-1134:1-1135)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 YEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLN
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES
910 920 930 940 950 960
970 980 990 1000 1010
pF1KA0 TQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNK-NVIAEHEIRNISCAAQDPEDL
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 TQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKQNVIAEHEIRNISCAAQDPEDL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 CTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAA
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA0 EMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTNFHWIS
1090 1100 1110 1120 1130 1140
XP_011 YWSKI
>>XP_005249021 (OMIM: 608994) PREDICTED: ankyrin repeat (1155 aa)
initn: 6566 init1: 6566 opt: 6576 Z-score: 3410.1 bits: 642.9 E(85289): 3.3e-183
Smith-Waterman score: 7478; 98.1% identity (98.1% similar) in 1155 aa overlap (1-1134:1-1155)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQN---------------------NDNETALHCAAQY
:::::::::::::::::::::::::: :::::::::::::
XP_005 AWKGDAQIVRLLIHQGPSHTRVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQY
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKN
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 VIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFE
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 VAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSW
1090 1100 1110 1120 1130 1140
1120 1130
pF1KA0 VVDPKPDSKRSLSTN
:::::::::::::::
XP_005 VVDPKPDSKRSLSTN
1150
>>XP_011512734 (OMIM: 608994) PREDICTED: ankyrin repeat (1165 aa)
initn: 6566 init1: 6566 opt: 6576 Z-score: 3410.1 bits: 642.9 E(85289): 3.3e-183
Smith-Waterman score: 7478; 98.1% identity (98.1% similar) in 1155 aa overlap (1-1134:1-1155)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQN---------------------NDNETALHCAAQY
:::::::::::::::::::::::::: :::::::::::::
XP_011 AWKGDAQIVRLLIHQGPSHTRVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQY
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKN
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 VIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFE
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 VAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSW
1090 1100 1110 1120 1130 1140
1120 1130
pF1KA0 VVDPKPDSKRSLSTN
:::::::::::::::
XP_011 VVDPKPDSKRSLSTNFHWISYWSKI
1150 1160
>>XP_011512738 (OMIM: 608994) PREDICTED: ankyrin repeat (1100 aa)
initn: 6342 init1: 5672 opt: 6564 Z-score: 3404.2 bits: 641.7 E(85289): 7.1e-183
Smith-Waterman score: 7026; 97.9% identity (97.9% similar) in 1090 aa overlap (67-1134:1-1090)
40 50 60 70 80 90
pF1KA0 GGGSGGGGGGSGGGGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVV
::::::::::::::::::::::::::::::
XP_011 MWRGPNVNCVDSTGYTPLHHAALNGHKDVV
10 20 30
100 110 120 130 140
pF1KA0 EVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNALEIKELKKY
40 50 60 70 80 90
150 160 170 180 190
pF1KA0 -----------NDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPFDPYINAKNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA0 EVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA0 LFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA0 DKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA0 MASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEV
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA0 LSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQV
400 410 420 430 440 450
500 510 520 530 540 550
pF1KA0 PEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGAS
460 470 480 490 500 510
560 570 580 590 600 610
pF1KA0 QPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKA
520 530 540 550 560 570
620 630 640 650 660 670
pF1KA0 ELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIM
580 590 600 610 620 630
680 690 700 710 720 730
pF1KA0 SSIGEGIDFSQERQKISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEE
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 SSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEE
640 650 660 670 680 690
740 750 760 770 780 790
pF1KA0 QDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSG
700 710 720 730 740 750
800 810 820 830 840 850
pF1KA0 YSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQ
760 770 780 790 800 810
860 870 880 890 900 910
pF1KA0 TSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRP
820 830 840 850 860 870
920 930 940 950 960 970
pF1KA0 PSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHM
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KA0 KKIPTIILSITYKGVKFIDASNK-NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHH
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_011 KKIPTIILSITYKGVKFIDASNKQNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHH
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KA0 YCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPR
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130
pF1KA0 VGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
::::::::::::::::::::::::::::::::::::::::
XP_011 VGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTNFHWISYWSKI
1060 1070 1080 1090 1100
>>XP_006715099 (OMIM: 608994) PREDICTED: ankyrin repeat (1156 aa)
initn: 6782 init1: 5672 opt: 6564 Z-score: 3403.9 bits: 641.7 E(85289): 7.3e-183
Smith-Waterman score: 7466; 98.0% identity (98.0% similar) in 1156 aa overlap (1-1134:1-1156)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQN---------------------NDNETALHCAAQY
:::::::::::::::::::::::::: :::::::::::::
XP_006 AWKGDAQIVRLLIHQGPSHTRVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQY
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_006 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKQ
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAF
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 EVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVS
1090 1100 1110 1120 1130 1140
1120 1130
pF1KA0 WVVDPKPDSKRSLSTN
::::::::::::::::
XP_006 WVVDPKPDSKRSLSTN
1150
>>XP_011512733 (OMIM: 608994) PREDICTED: ankyrin repeat (1166 aa)
initn: 6782 init1: 5672 opt: 6564 Z-score: 3403.9 bits: 641.7 E(85289): 7.4e-183
Smith-Waterman score: 7466; 98.0% identity (98.0% similar) in 1156 aa overlap (1-1134:1-1156)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQN---------------------NDNETALHCAAQY
:::::::::::::::::::::::::: :::::::::::::
XP_011 AWKGDAQIVRLLIHQGPSHTRVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQY
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKQ
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAF
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 EVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVS
1090 1100 1110 1120 1130 1140
1120 1130
pF1KA0 WVVDPKPDSKRSLSTN
::::::::::::::::
XP_011 WVVDPKPDSKRSLSTNFHWISYWSKI
1150 1160
>>XP_011512735 (OMIM: 608994) PREDICTED: ankyrin repeat (1162 aa)
initn: 6782 init1: 5672 opt: 6557 Z-score: 3400.3 bits: 641.1 E(85289): 1.2e-182
Smith-Waterman score: 7459; 98.0% identity (98.0% similar) in 1155 aa overlap (1-1133:1-1155)
10 20 30 40 50 60
pF1KA0 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLA
70 80 90 100 110 120
130 140 150
pF1KA0 AWKGDAQIVRLLIHQGPSHTRVNEQN---------------------NDNETALHCAAQY
:::::::::::::::::::::::::: :::::::::::::
XP_011 AWKGDAQIVRLLIHQGPSHTRVNEQNALEIKELKKYGPFDPYINAKNNDNETALHCAAQY
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRS
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGSRTLEQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFES
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKQ
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAF
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 EVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVS
1090 1100 1110 1120 1130 1140
1120 1130
pF1KA0 WVVDPKPDSKRSLSTN
:::::::::::::::
XP_011 WVVDPKPDSKRSLSTKYETTIF
1150 1160
>>XP_016866082 (OMIM: 608994) PREDICTED: ankyrin repeat (593 aa)
initn: 3916 init1: 3916 opt: 3916 Z-score: 2042.0 bits: 388.8 E(85289): 5.3e-107
Smith-Waterman score: 3916; 99.8% identity (99.8% similar) in 593 aa overlap (542-1134:1-593)
520 530 540 550 560 570
pF1KA0 VGQDPFQLLCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTG
::::::::::::::::::::::::::::::
XP_016 MQLEETGVHAPGASQPSALDQSKRVGYLTG
10 20 30
580 590 600 610 620 630
pF1KA0 LPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLL
40 50 60 70 80 90
640 650 660 670 680 690
pF1KA0 TCSPTEDATMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCSPTEDATMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKI
100 110 120 130 140 150
700 710 720 730 740 750
pF1KA0 SGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRK
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRK
160 170 180 190 200 210
760 770 780 790 800 810
pF1KA0 LLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELV
220 230 240 250 260 270
820 830 840 850 860 870
pF1KA0 NVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSA
280 290 300 310 320 330
880 890 900 910 920 930
pF1KA0 DLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQ
340 350 360 370 380 390
940 950 960 970 980 990
pF1KA0 PEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVK
400 410 420 430 440 450
1000 1010 1020 1030 1040 1050
pF1KA0 FIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEII
460 470 480 490 500 510
1060 1070 1080 1090 1100 1110
pF1KA0 LTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDA
520 530 540 550 560 570
1120 1130
pF1KA0 QSHASVSWVVDPKPDSKRSLSTN
:::::::::::::::::::::::
XP_016 QSHASVSWVVDPKPDSKRSLSTN
580 590
1134 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:13:35 2016 done: Thu Nov 3 09:13:38 2016
Total Scan time: 18.680 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]