FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0244, 2039 aa 1>>>pF1KA0244 2039 - 2039 aa - 2039 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.8857+/-0.00139; mu= -3.4977+/- 0.084 mean_var=431.9312+/-86.992, 0's: 0 Z-trim(110.8): 38 B-trim: 0 in 0/53 Lambda= 0.061712 statistics sampled from 11868 (11892) to 11868 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.365), width: 16 Scan time: 5.750 The best scores are: opt bits E(32554) CCDS4966.1 PHF3 gene_id:23469|Hs108|chr6 (2039) 13591 1226.5 0 CCDS78155.1 PHF3 gene_id:23469|Hs108|chr6 ( 736) 4828 446.0 2.7e-124 CCDS33506.1 DIDO1 gene_id:11083|Hs108|chr20 (2240) 743 82.7 1.9e-14 CCDS13508.2 DIDO1 gene_id:11083|Hs108|chr20 (1189) 644 73.6 5.3e-12 >>CCDS4966.1 PHF3 gene_id:23469|Hs108|chr6 (2039 aa) initn: 13591 init1: 13591 opt: 13591 Z-score: 6555.4 bits: 1226.5 E(32554): 0 Smith-Waterman score: 13591; 100.0% identity (100.0% similar) in 2039 aa overlap (1-2039:1-2039) 10 20 30 40 50 60 pF1KA0 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 pF1KA0 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 1990 2000 2010 2020 2030 >>CCDS78155.1 PHF3 gene_id:23469|Hs108|chr6 (736 aa) initn: 4820 init1: 4820 opt: 4828 Z-score: 2344.8 bits: 446.0 E(32554): 2.7e-124 Smith-Waterman score: 4828; 99.5% identity (99.6% similar) in 735 aa overlap (1-735:1-735) 10 20 30 40 50 60 pF1KA0 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS78 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL :::::::::: . : CCDS78 GFCKKPHGNRCVCMCV 730 >>CCDS33506.1 DIDO1 gene_id:11083|Hs108|chr20 (2240 aa) initn: 1653 init1: 728 opt: 743 Z-score: 372.9 bits: 82.7 E(32554): 1.9e-14 Smith-Waterman score: 1276; 29.1% identity (51.5% similar) in 1310 aa overlap (862-1923:595-1870) 840 850 860 870 880 890 pF1KA0 RESGEGRNSSDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKS-EKIPKESTTVTCTGEKA : : :. .: . ... . .. : CCDS33 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA 570 580 590 600 610 620 900 910 920 930 940 pF1KA0 SK--PGTHEKQEMKKKKVEKGVLNVHPA--------ASASKPSADQIRQSVRHSLKDILM :: ::. .: : .: . :: :. :.:.. ::::..:.:::.:: CCDS33 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNS-QIRQNIRRSLKEILW 630 640 650 660 670 680 950 960 970 980 990 pF1KA0 KRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKK ::..::. : . :....:.: .::::.:..:. :: .::.::::.:::::::::. ::.. CCDS33 KRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHR 690 700 710 720 730 740 1000 1010 1020 1030 1040 1050 pF1KA0 VLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEI ::. :.. .:.:..::::.::::..:..: : ..: : . : .. : ... CCDS33 VLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKK---TAPRQEAIP 750 760 770 780 790 800 1060 1070 1080 1090 1100 1110 pF1KA0 EIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQKEEV-DSMSKDTTSQHRQHLFDLNC ..:.. :....: : :: : ... :: : .: .:: :::::::: ::::::: CCDS33 DLEDSPPVSDSE---EQQESA--RAV--PEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNC 810 820 830 840 850 1120 1130 1140 1150 pF1KA0 KICIGRMAPPVDDLSPKKVKVVVGVAR-----KHS--------DNEAESIADAL------ ::: :.. :. .::: :. ..: . ::. :. : . .:. CCDS33 KICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASE 860 870 880 890 900 910 1160 pF1KA0 -----------------------------------------------------------S : CCDS33 PGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPS 920 930 940 950 960 970 1170 1180 1190 pF1KA0 STSNILASE-------FFEEEKQESPKSTF---------------SPAPR----PEMPGT :. . .:: . : .:. :: .. :: :: : :. CCDS33 SSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNI 980 990 1000 1010 1020 1030 1200 1210 1220 1230 1240 pF1KA0 VEVEST---------FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQV :: ::.::. :::::::: :::::::::::::: .::.:::::.:.. CCDS33 STSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHI 1040 1050 1060 1070 1080 1090 1250 1260 1270 1280 1290 1300 pF1KA0 GGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNM ::::.:.:::::: :.:.: .::.:..:: :.:::....: :..::::: :.::.::: CCDS33 GGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNN 1100 1110 1120 1130 1140 1150 1310 1320 1330 1340 1350 pF1KA0 KQVKDMYLIPLGATDKIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKR------------ ..:::.:::::.: : .: :.::.::::: :::..:::.: ::.:: CCDS33 RHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDE 1160 1170 1180 1190 1200 1210 1360 1370 1380 pF1KA0 -----------------------------QHSACASTSHIAETPESAPPIALPPDKKSKI .. :.. . .. :: ..:: : . . CCDS33 KRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVL 1220 1230 1240 1250 1260 1270 1390 1400 1410 1420 1430 1440 pF1KA0 EVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVT--KQEPPKP-LR .: . : . . :.. . . . . .: .... :.. : : CCDS33 KVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAR 1280 1290 1300 1310 1320 1330 1450 1460 1470 1480 1490 1500 pF1KA0 FLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLNE :: : ..: : :. .:. .:. .. :: ... ... :.. . :. : CCDS33 EPPGSTAGLPQEPKT--TAEDGVPAPPLLDPIVQQFGQ-FSKDKALEEEEDDR--PYDPE 1340 1350 1360 1370 1380 1510 1520 1530 1540 1550 pF1KA0 QTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSA---EIETSVVGSSSISAGSLTS- . . . :. : :. .:.. . . .. : : :: .. ..... .: . CCDS33 EEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDET-ILEEAKVTVDDLPNR 1390 1400 1410 1420 1430 1440 1560 1570 1580 1590 1600 1610 pF1KA0 --LSLRG----KPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTS ..: .: . . : .: :.:. : .... . :::: :.::. :...... CCDS33 MCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQL-EEQEEALRQQRAA 1450 1460 1470 1480 1490 1500 1620 1630 1640 1650 pF1KA0 --------------NSSPCRSNVGKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAG : : .:.. :... . . : . :. . : : .:::::: CCDS33 VGVSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPASQASN-HRDPRQA-- 1510 1520 1530 1540 1550 1560 1660 1670 1680 1690 1700 pF1KA0 RSQPVTTSESKDGDSCR---NGEKHMLPGLSHNKEHLTEQINV---EEK------LCSAE : . :.:.. : : . :: . .. :. : . ::: :.: CCDS33 RRLATETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWASGE 1570 1580 1590 1600 1610 1620 1710 1720 1730 1740 1750 pF1KA0 KNSCVQQSDNLKVAQNSPSVE-NIQTSQAEQAK----P------LQEDILMQNIETVHPF : ...:. :. . . .. :.:. :. : :: . .:. :: CCDS33 KPPAGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQHDGERDPF 1630 1640 1650 1660 1670 1680 1760 1770 1780 1790 1800 pF1KA0 R------RGSAVATSHFEVGNTCPSEFPSKSI---TFTSRSTSPRTSTNFSPMRPQQPNL . .:......: . : :.: : .: . : . . .:. : :. CCDS33 TCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPP--PGQ 1690 1700 1710 1720 1730 1740 1810 1820 1830 1840 pF1KA0 QHLKSSPP--GFPFPGP----------PNFP-PQSMFGFPPHLPP--------PLLPPPG . :.:: : ::: :::: :. : : .: : :::. CCDS33 KVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPR---GPAPPFPEENIASNDGPRGPPPA 1750 1760 1770 1780 1790 1850 1860 1870 1880 1890 1900 pF1KA0 -FGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGR :: ..:. : : :: . : ::.. : . ::. :: :. CCDS33 RFGAQKGPIPSLFSGQHGPPPYGDSRGP--SPSYLGGPRG---VAPSQFEERK--DPHGE 1800 1810 1820 1830 1840 1850 1910 1920 1930 1940 1950 1960 pF1KA0 QDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSRE . . : : :.:. : .: CCDS33 KREFQ-DAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPS 1860 1870 1880 1890 1900 1910 >>CCDS13508.2 DIDO1 gene_id:11083|Hs108|chr20 (1189 aa) initn: 1390 init1: 636 opt: 644 Z-score: 328.9 bits: 73.6 E(32554): 5.3e-12 Smith-Waterman score: 1068; 37.8% identity (59.0% similar) in 598 aa overlap (862-1333:595-1181) 840 850 860 870 880 890 pF1KA0 RESGEGRNSSDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKS-EKIPKESTTVTCTGEKA : : :. .: . ... . .. : CCDS13 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA 570 580 590 600 610 620 900 910 920 930 940 pF1KA0 SK--PGTHEKQEMKKKKVEKGVLNVHPA--------ASASKPSADQIRQSVRHSLKDILM :: ::. .: : .: . :: :. :.:.. ::::..:.:::.:: CCDS13 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNS-QIRQNIRRSLKEILW 630 640 650 660 670 680 950 960 970 980 990 pF1KA0 KRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKK ::..::. : . :....:.: .::::.:..:. :: .::.::::.:::::::::. ::.. CCDS13 KRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHR 690 700 710 720 730 740 1000 1010 1020 1030 1040 1050 pF1KA0 VLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEI ::. :.. .:.:..::::.::::..:..: : ..: : . : .. : ... CCDS13 VLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKK---TAPRQEAIP 750 760 770 780 790 800 1060 1070 1080 1090 1100 1110 pF1KA0 EIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQKEEV-DSMSKDTTSQHRQHLFDLNC ..:.. :....: : :: : ... :: : .: .:: :::::::: ::::::: CCDS13 DLEDSPPVSDSE---EQQESA--RAV--PEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNC 810 820 830 840 850 1120 1130 1140 1150 pF1KA0 KICIGRMAPPVDDLSPKKVKVVVGVAR-----KHS--------DNEAESIADAL------ ::: :.. :. .::: :. ..: . ::. :. : . .:. CCDS13 KICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASE 860 870 880 890 900 910 1160 pF1KA0 -----------------------------------------------------------S : CCDS13 PGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPS 920 930 940 950 960 970 1170 1180 1190 pF1KA0 STSNILASE-------FFEEEKQESPKSTF---------------SPAPR----PEMPGT :. . .:: . : .:. :: .. :: :: : :. CCDS13 SSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNI 980 990 1000 1010 1020 1030 1200 1210 1220 1230 1240 pF1KA0 VEVEST---------FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQV :: ::.::. :::::::: :::::::::::::: .::.:::::.:.. CCDS13 STSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHI 1040 1050 1060 1070 1080 1090 1250 1260 1270 1280 1290 1300 pF1KA0 GGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNM ::::.:.:::::: :.:.: .::.:..:: :.:::....: :..::::: :.::.::: CCDS13 GGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNN 1100 1110 1120 1130 1140 1150 1310 1320 1330 1340 1350 1360 pF1KA0 KQVKDMYLIPLGATDKIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIA ..:::.:::::.: : .: :.::.::: CCDS13 RHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR 1160 1170 1180 2039 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:25:58 2016 done: Wed Nov 2 18:25:59 2016 Total Scan time: 5.750 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]