FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0292, 1960 aa 1>>>pF1KA0292 1960 - 1960 aa - 1960 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.0692+/-0.00107; mu= -10.2198+/- 0.064 mean_var=405.0574+/-81.702, 0's: 0 Z-trim(115.3): 34 B-trim: 0 in 0/53 Lambda= 0.063726 statistics sampled from 15824 (15851) to 15824 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.487), width: 16 Scan time: 5.470 The best scores are: opt bits E(32554) CCDS14033.1 TCF20 gene_id:6942|Hs108|chr22 (1960) 13403 1247.8 0 CCDS14032.1 TCF20 gene_id:6942|Hs108|chr22 (1938) 13212 1230.2 0 CCDS11188.1 RAI1 gene_id:10743|Hs108|chr17 (1906) 1190 125.0 2.9e-27 >>CCDS14033.1 TCF20 gene_id:6942|Hs108|chr22 (1960 aa) initn: 13403 init1: 13403 opt: 13403 Z-score: 6671.0 bits: 1247.8 E(32554): 0 Smith-Waterman score: 13403; 99.9% identity (100.0% similar) in 1960 aa overlap (1-1960:1-1960) 10 20 30 40 50 60 pF1KA0 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 VGGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 pF1KA0 HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG :::::::::::::::::::::::::::::::::::::::: CCDS14 HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG 1930 1940 1950 1960 >>CCDS14032.1 TCF20 gene_id:6942|Hs108|chr22 (1938 aa) initn: 13212 init1: 13212 opt: 13212 Z-score: 6576.2 bits: 1230.2 E(32554): 0 Smith-Waterman score: 13212; 99.9% identity (100.0% similar) in 1933 aa overlap (1-1933:1-1933) 10 20 30 40 50 60 pF1KA0 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 VGGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 pF1KA0 HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG ::::::::::::: CCDS14 HEENFSVRCPKHKVRLWR 1930 >>CCDS11188.1 RAI1 gene_id:10743|Hs108|chr17 (1906 aa) initn: 1159 init1: 434 opt: 1190 Z-score: 602.9 bits: 125.0 E(32554): 2.9e-27 Smith-Waterman score: 1663; 27.0% identity (52.8% similar) in 2067 aa overlap (1-1933:1-1903) 10 20 30 40 50 pF1KA0 MQSFREQSSYHGNQQSYPQEVHGSSRLEEF-SPRQA------QMFQNFGGTGGSSGSSGS ::::::. ..::.::.: : . .::::.. .: :: : . . . : CCDS11 MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 GSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSG :..: :.:::.:: . :.: ... . : : : ..: : . CCDS11 GGAGTPSGTAAAVAA----DKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEE 70 80 90 100 110 120 130 140 150 160 170 pF1KA0 PVQSYGPPQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFS-PGSAQYQQQAS .:..: :: : : .: :..:... . : : :: .:.. CCDS11 SLQAWGAPQPPP-----------PQPQPLPAG---VAKYDENLMKKTAVPPSRQYAEQGA 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 SQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVG-QF :: ..:. .. : :: :: . . .:: . . :. . : .: CCDS11 ------QVPFRTHSLHVQQPPPPQ---QPLAYPK----LQRQKLQNDIASPLPFPQGTHF 170 180 190 200 240 250 260 270 280 pF1KA0 GQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYG--TQSN :: :: .::. :: : : .:...:: : .. ... .. ..:.. : : .:. CCDS11 PQHSQSFPTSSTYSS--SVQGGGQGAHSYK-SCTAPTAQPHDRPLTASSSLAPGQRVQNL 210 220 230 240 250 260 290 300 310 320 330 340 pF1KA0 YSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQ-YN ..:: . ...: . : :: ::::: :..: .:....: : : : .: :: : CCDS11 HAYQSGRL-SYDQQQ--QQQQQQQQQQQALQSRHHAQETLHYQNLA-KYQHYGQQGQGYC 270 280 290 300 310 320 350 360 370 380 390 400 pF1KA0 QPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ-----GSV ::.. ::.: :..:.::: :. ::: :: .::: :::::::: . ::. .: :. CCDS11 QPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAF 330 340 350 360 370 380 410 420 430 440 450 460 pF1KA0 PMGSRNRILQLMPQLSPTPS-MMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQ : : .. ..:: :.:.:. : ...:.. : . . .::. :.: .:.::.::..: CCDS11 PAGITDHS-HFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQ 390 400 410 420 430 440 470 480 490 500 510 pF1KA0 VANLPNTVQHMLLSDALTPQKKTSK----RPSSSKKADSCTNSEGSSQPEEQLKSPMAES : :. ::::..::: : .:::: : : ..:.. :. :::. : .:..: CCDS11 VENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCS-PEGSGYSAEPAGTPLSEP 450 460 470 480 490 500 520 530 540 550 560 570 pF1KA0 LDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQN---EPPRLNASP .. .:.. . ... :::. . .. ..: .:::. .: .: ... CCDS11 -PSSTPQSTHAEPQEADYLSGSEDPLERSFL--YCNQARGSPARVNSNSKAKPESVSTCS 510 520 530 540 550 580 590 600 610 pF1KA0 AAREEATSPGAKD--------MPLSSDGNPKVNEKTVGVIV----SREAMTGRV----EK .. . : . : .::.: .. ..:. .. ..: ..... : CCDS11 VTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEA 560 570 580 590 600 610 620 630 640 650 660 670 pF1KA0 PGGQDKGSQEDDPAATQ---RPP---SNGGAKETSHASLPQPEPPGGGGSKGNKNGDNNS : . . . :. .. .:: : .: : :. :.: . . . :... CCDS11 IGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPRPGEPEALPDSLQLDKGG 620 630 640 650 660 670 680 690 700 710 720 730 pF1KA0 NHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPR-NVGGFPQYP--TG : . . : ... :.. .:.:. : : .. : ..: .: ....: .: :. CCDS11 NAKDFSPGLFEDPSVA--FAT-PDPKKTTGPLSFGTKPTLGVPAPDPTTAAFDCFPDTTA 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 QEKGD----FTGHGERKG----RNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAGSL ..: :. : : : :. : . :. . : . .:.: .. : CCDS11 ASSADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGISKGDTHEASACLGFQ 740 750 760 770 780 790 790 800 810 820 830 pF1KA0 EGTTRPNVLVSQTNELASR--GLLNKSIGSLLENPH------WGPWERKSSSTAPEMKQI : . ..: ... .. : ... :.::. :. : :. ::: .. .. CCDS11 EEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLEDSRHCCSTA-DFGDL 800 810 820 830 840 850 840 850 860 870 880 pF1KA0 NLTDYPIPRKFEIEPQ---SSAHEPGGSLSERRSVICDISPLRQIV--RDPGAHSLGHMS : : :: ..: . :: : :: .: .. .:: .. .. . : CCDS11 PLLP-PTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICTKEEVEEVL---- 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 ADTRIGRNDRLNPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGD :.. : .. . . ..:::: : :. :.:..: ::.: : CCDS11 -DSKAGWGSPCHLS-GESVILLGPTVGTESKVQSW--------FESSLS----------- 910 920 930 940 950 960 970 980 990 1000 pF1KA0 HCHPPSIKHESYRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGM-RGRS--P : .: .:. :. .:: .: : .. . . ..:. . ..: .. .: . ::.: CCDS11 HMKPG---EEGPDGERAPGDST-TSDASLAQKPNKPA-VPEAP--IAKKEPVPRGKSLRS 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KA0 SQYHDFAEKLKMSPGRSRGPGGDPHHMNPHM-TFSERANRSSLHTPFSPNSETL----AS . : . . :: :.: . :. : ... . .: :: : . CCDS11 RRVHRGLPEAEDSP--CRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTR 1010 1020 1030 1040 1050 1070 1080 1090 1100 1110 1120 pF1KA0 AYHANTRAHAYGDPNAGLNSQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPR- . : .. .. : : ::.. .. .: .: ::. : . .:. CCDS11 SLTALSEPRTPGPP--GLTTTPAPPDKLGGKQRAAFK---SGKRVG--------KPSPKA 1060 1070 1080 1090 1100 1130 1140 1150 1160 1170 pF1KA0 -KSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKH .:: . : :. .:.. : : . .:: . : ...: :. CCDS11 ASSPSNPAAL-----PVASDSSPM--GSKTKETDSPS----------TPGKDQRSMILR- 1110 1120 1130 1140 1180 1190 1200 1210 1220 1230 pF1KA0 GSQKLQESCWDLSRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRL . : :: :.. :... : ...: : .. . : : : : : CCDS11 SRTKTQEIFH--SKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQ--KEGRVSQRA 1150 1160 1170 1180 1190 1200 1240 1250 1260 1270 1280 1290 pF1KA0 ----PGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKN---SSTEDKGRLLHSSKEGA :: .. :. :: .: .:..:.:.:... ... ::.. .: ...: CCDS11 RVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERP 1210 1220 1230 1240 1250 1260 1300 1310 1320 1330 1340 pF1KA0 DKAFNSYAHLSHSQDIKSIPKRDSSKD---LPSPDSRN-C----PAVTLTSPAKTKILPP . . . . ..: . :. : . ... :: :.. . : ... . :::.::: CCDS11 EGSPTLFKRMSSPK--KAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLPP 1270 1280 1290 1300 1310 1320 1350 1360 1370 1380 1390 pF1KA0 RKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTVT--LDDI---LSLKSGPPEG---G ::::::::::::::::::.... : . . . :. .. :.: :. .: : : : CCDS11 RKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEG 1330 1340 1350 1360 1370 1380 1400 1410 1420 1430 1440 1450 pF1KA0 SVAVQDADIEKRKGEVASDLV-SPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVT : : .. .: :. : .:.:. : . : :. . : : ::: : : CCDS11 LVNVGTGQKLPTSG--ADPLCRNPTNRSL--KGKLMNSK---KLSSTDCFKTE--AFTSP 1390 1400 1410 1420 1430 1460 1470 1480 1490 1500 1510 pF1KA0 AGKEPPGAMTSTTSQKPGSNQGRPDGSLG-GTAPLIFPDSKNVPPVGILAPEANPKAEEK . .: : .. . : : .:: :. : . .:: . :. .:.:. .. CCDS11 EALQPGG---TALAPKKRSRKGRA-GAHGLSKGPL--EKRPYLGPALLLTPR------DR 1440 1450 1460 1470 1480 1520 1530 1540 1550 1560 1570 pF1KA0 ENDTVTISPKQEGFPPKGYFPSGKK-KGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADG . : : . : : .::: : . .: . .: . .: : . . : : .. CCDS11 ASGTQGASEDNSG----G---GGKKPKMEELG-LASQPPEGRPCQPQTRAQKQP-GHTNY 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 pF1KA0 EPKPKKQRQRRERRK-----PGAQPRKRKTKQAVPIVEPQEPEIKLKYATQ-PLDKTDAK :..: : : : : ::. .: : ..: ::::.::: .. ..:.. CCDS11 SSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSR 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 pF1KA0 NKSFYPYIHVVNKCELGAVCTIINAE------EEEQTKLVRGRKGQRSLT---------- . .: :...: .. . ..::..:. ... .. . . ... :.. CCDS11 TPAFSPFVRVEKRDAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLAT 1600 1610 1620 1630 1640 1650 1680 1690 1700 1710 1720 pF1KA0 -PPPSSTESK-ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDY : : . . .:: :: : ::::... . :::::: . :.....::: ::.::. CCDS11 LPGGSILQPRPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEH- 1660 1670 1680 1690 1700 1710 1730 1740 1750 1760 1770 1780 pF1KA0 AATLPKNPPPKRATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRR :::. : :...: .:. .. :. . : . :. . : CCDS11 --CLPKKKP-----------KLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKPPRP 1720 1730 1740 1750 1790 1800 1810 1820 1830 1840 pF1KA0 HRSED-CGGGP-RSLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPL : :: :. .::: .. . . .. ..:. . : . : : CCDS11 DGPADPAKQGPLRTSARGLS-RRLQSCYCCDGREDGGEEAAPADKGRKHECSKEAPAEPG 1760 1770 1780 1790 1800 1810 1850 1860 1870 1880 1890 1900 pF1KA0 -DSNEFWVHEGCILWANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSF ...: ::::.: .:..:.::: :.:.:::::...: .: :: :::::::.:: .::: CCDS11 GEAQEHWVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLH 1820 1830 1840 1850 1860 1870 1910 1920 1930 1940 1950 1960 pF1KA0 RYHYPCAIDADCLLHEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG :::::: :: :.. :::::..::::: CCDS11 TYHYPCASDAGCIFIEENFSLKCPKHKRLP 1880 1890 1900 1960 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:39:44 2016 done: Sat Nov 5 06:39:45 2016 Total Scan time: 5.470 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]