Result of FASTA (omim) for pF1KA0302
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0302, 2390 aa
  1>>>pF1KA0302 2390 - 2390 aa - 2390 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.1702+/-0.000549; mu= -7.9050+/- 0.034
 mean_var=327.9683+/-68.809, 0's: 0 Z-trim(117.2): 470  B-trim: 480 in 2/51
 Lambda= 0.070820
 statistics sampled from 28567 (29079) to 28567 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.341), width:  16
 Scan time: 27.590

The best scores are:                                      opt bits E(85289)
NP_008877 (OMIM: 600224,604985,615386) spectrin be (2390) 15697 1619.8       0
XP_016873666 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_006718734 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_016873667 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_005274250 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_005274249 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_016873663 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_016873665 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_016873664 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9       0
XP_006718732 (OMIM: 600224,604985,615386) PREDICTE (2397) 15361 1585.4       0
XP_016860268 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2       0
XP_016860269 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2       0
XP_005264574 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2       0
XP_006712150 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2       0
XP_016860270 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2       0
NP_003119 (OMIM: 182790) spectrin beta chain, non- (2364) 9418 978.2       0
XP_005264575 (OMIM: 182790) PREDICTED: spectrin be (2351) 9194 955.3       0
NP_842565 (OMIM: 182790) spectrin beta chain, non- (2155) 9162 952.0       0
XP_011543519 (OMIM: 600224,604985,615386) PREDICTE (1432) 8387 872.8       0
XP_011543518 (OMIM: 600224,604985,615386) PREDICTE (1452) 8387 872.8       0
XP_016877102 (OMIM: 182870,616649) PREDICTED: spec (2287) 7755 808.3       0
NP_001020029 (OMIM: 182870,616649) spectrin beta c (2328) 7755 808.3       0
XP_005268080 (OMIM: 182870,616649) PREDICTED: spec (2328) 7755 808.3       0
XP_016877101 (OMIM: 182870,616649) PREDICTED: spec (2328) 7755 808.3       0
NP_000338 (OMIM: 182870,616649) spectrin beta chai (2137) 7724 805.1       0
XP_016877103 (OMIM: 182870,616649) PREDICTED: spec (2137) 7724 805.1       0
XP_011535407 (OMIM: 182870,616649) PREDICTED: spec (1554) 5840 612.6 1.3e-173
XP_016882540 (OMIM: 606214) PREDICTED: spectrin be (2129) 2952 317.6 1.1e-84
XP_011525475 (OMIM: 606214) PREDICTED: spectrin be (2351) 2952 317.6 1.2e-84
NP_066022 (OMIM: 606214) spectrin beta chain, non- (2564) 2952 317.6 1.3e-84
XP_016882538 (OMIM: 606214) PREDICTED: spectrin be (2564) 2952 317.6 1.3e-84
XP_016882541 (OMIM: 606214) PREDICTED: spectrin be (1309) 2890 311.1 5.9e-83
XP_016882539 (OMIM: 606214) PREDICTED: spectrin be (2450) 2525 274.0 1.7e-71
NP_079489 (OMIM: 606214) spectrin beta chain, non- ( 678) 1779 197.5 4.9e-49
XP_016870548 (OMIM: 182810,613477) PREDICTED: spec (2471) 1729 192.6 5.2e-47
NP_003118 (OMIM: 182810,613477) spectrin alpha cha (2472) 1729 192.6 5.2e-47
NP_001123910 (OMIM: 182810,613477) spectrin alpha  (2477) 1729 192.6 5.2e-47
XP_006717313 (OMIM: 182810,613477) PREDICTED: spec (2483) 1729 192.6 5.2e-47
XP_006717312 (OMIM: 182810,613477) PREDICTED: spec (2484) 1729 192.6 5.2e-47
XP_006717311 (OMIM: 182810,613477) PREDICTED: spec (2489) 1729 192.6 5.2e-47
XP_006717317 (OMIM: 182810,613477) PREDICTED: spec (2498) 1729 192.6 5.2e-47
XP_006717309 (OMIM: 182810,613477) PREDICTED: spec (2505) 1729 192.6 5.3e-47
XP_006717308 (OMIM: 182810,613477) PREDICTED: spec (2510) 1729 192.6 5.3e-47
XP_016877794 (OMIM: 605916) PREDICTED: spectrin be (1856) 1663 185.8 4.3e-45
NP_001182461 (OMIM: 182810,613477) spectrin alpha  (2452) 1664 186.0 5.1e-45
XP_016870550 (OMIM: 182810,613477) PREDICTED: spec (2457) 1664 186.0 5.2e-45
XP_016870549 (OMIM: 182810,613477) PREDICTED: spec (2463) 1664 186.0 5.2e-45
XP_006717316 (OMIM: 182810,613477) PREDICTED: spec (2464) 1664 186.0 5.2e-45
XP_006717315 (OMIM: 182810,613477) PREDICTED: spec (2469) 1664 186.0 5.2e-45
XP_006717314 (OMIM: 182810,613477) PREDICTED: spec (2478) 1664 186.0 5.2e-45


>>NP_008877 (OMIM: 600224,604985,615386) spectrin beta c  (2390 aa)
 initn: 15697 init1: 15697 opt: 15697  Z-score: 8678.1  bits: 1619.8 E(85289):    0
Smith-Waterman score: 15697; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_016873666 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_006718734 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_006 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_016873667 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_005274250 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_005 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_005274249 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_005 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_016873663 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_016873665 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_016873664 (OMIM: 600224,604985,615386) PREDICTED: s  (2390 aa)
 initn: 15689 init1: 15689 opt: 15689  Z-score: 8673.7  bits: 1618.9 E(85289):    0
Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390)

               10        20        30        40        50        60
pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390
pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
             2350      2360      2370      2380      2390

>>XP_006718732 (OMIM: 600224,604985,615386) PREDICTED: s  (2397 aa)
 initn: 15356 init1: 15356 opt: 15361  Z-score: 8492.6  bits: 1585.4 E(85289):    0
Smith-Waterman score: 15361; 99.4% identity (99.7% similar) in 2356 aa overlap (35-2390:43-2397)

           10        20        30        40        50        60    
pF1KA0 LSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQKKTFT
                                     : .. : ..: .:.: : ::::::::::::
XP_006 GLHEASEFYYEAVEGAHNPGGLLLSPAAFINPAQYASVLE-GRFKQLQDEREAVQKKTFT
             20        30        40        50         60        70 

           70        80        90       100       110       120    
pF1KA0 KWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQ
              80        90       100       110       120       130 

          130       140       150       160       170       180    
pF1KA0 FLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLL
             140       150       160       170       180       190 

          190       200       210       220       230       240    
pF1KA0 WCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLA
             200       210       220       230       240       250 

          250       260       270       280       290       300    
pF1KA0 EKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAE
             260       270       280       290       300       310 

          310       320       330       340       350       360    
pF1KA0 RLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGN
             320       330       340       350       360       370 

          370       380       390       400       410       420    
pF1KA0 LEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLE
             380       390       400       410       420       430 

          430       440       450       460       470       480    
pF1KA0 QLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAV
             440       450       460       470       480       490 

          490       500       510       520       530       540    
pF1KA0 DAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLM
             500       510       520       530       540       550 

          550       560       570       580       590       600    
pF1KA0 DWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNPGKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNPGKEY
             560       570       580       590       600       610 

          610       620       630       640       650       660    
pF1KA0 RPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLL
             620       630       640       650       660       670 

          670       680       690       700       710       720    
pF1KA0 ASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAE
             680       690       700       710       720       730 

          730       740       750       760       770       780    
pF1KA0 LQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQA
             740       750       760       770       780       790 

          790       800       810       820       830       840    
pF1KA0 LARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQARAGER
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_006 LARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQARAGER
             800       810       820       830       840       850 

          850       860       870       880       890       900    
pF1KA0 ARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTL
             860       870       880       890       900       910 

          910       920       930       940       950       960    
pF1KA0 AAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYH
             920       930       940       950       960       970 

          970       980       990      1000      1010      1020    
pF1KA0 LECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANA
             980       990      1000      1010      1020      1030 

         1030      1040      1050      1060      1070      1080    
pF1KA0 LAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRT
            1040      1050      1060      1070      1080      1090 

         1090      1100      1110      1120      1130      1140    
pF1KA0 QTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQCLFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQCLFLR
            1100      1110      1120      1130      1140      1150 

         1150      1160      1170      1180      1190      1200    
pF1KA0 QRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTL
            1160      1170      1180      1190      1200      1210 

         1210      1220      1230      1240      1250      1260    
pF1KA0 QAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQ
            1220      1230      1240      1250      1260      1270 

         1270      1280      1290      1300      1310      1320    
pF1KA0 DAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMA
            1280      1290      1300      1310      1320      1330 

         1330      1340      1350      1360      1370      1380    
pF1KA0 ELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANR
            1340      1350      1360      1370      1380      1390 

         1390      1400      1410      1420      1430      1440    
pF1KA0 AELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQA
            1400      1410      1420      1430      1440      1450 

         1450      1460      1470      1480      1490      1500    
pF1KA0 QAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWV
            1460      1470      1480      1490      1500      1510 

         1510      1520      1530      1540      1550      1560    
pF1KA0 TERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAGPELA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAGPELA
            1520      1530      1540      1550      1560      1570 

         1570      1580      1590      1600      1610      1620    
pF1KA0 ELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQ
            1580      1590      1600      1610      1620      1630 

         1630      1640      1650      1660      1670      1680    
pF1KA0 AEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAG
            1640      1650      1660      1670      1680      1690 

         1690      1700      1710      1720      1730      1740    
pF1KA0 ERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTS
            1700      1710      1720      1730      1740      1750 

         1750      1760      1770      1780      1790      1800    
pF1KA0 TIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQ
            1760      1770      1780      1790      1800      1810 

         1810      1820      1830      1840      1850      1860    
pF1KA0 RFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGH
            1820      1830      1840      1850      1860      1870 

         1870      1880      1890      1900      1910      1920    
pF1KA0 RLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMD
            1880      1890      1900      1910      1920      1930 

         1930      1940      1950      1960      1970      1980    
pF1KA0 EVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEI
            1940      1950      1960      1970      1980      1990 

         1990      2000      2010      2020      2030      2040    
pF1KA0 SEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCT
            2000      2010      2020      2030      2040      2050 

         2050      2060      2070      2080      2090      2100    
pF1KA0 VDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPT
            2060      2070      2080      2090      2100      2110 

         2110      2120      2130      2140      2150      2160    
pF1KA0 ASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEHSSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEHSSFP
            2120      2130      2140      2150      2160      2170 

         2170      2180      2190      2200      2210      2220    
pF1KA0 EGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQMEGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQMEGM
            2180      2190      2200      2210      2220      2230 

         2230      2240      2250      2260      2270      2280    
pF1KA0 LCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGS
            2240      2250      2260      2270      2280      2290 

         2290      2300      2310      2320      2330      2340    
pF1KA0 VAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPS
            2300      2310      2320      2330      2340      2350 

         2350      2360      2370      2380      2390
pF1KA0 TTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
            2360      2370      2380      2390       




2390 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:22:26 2016 done: Sat Nov  5 01:22:30 2016
 Total Scan time: 27.590 Total Display time:  2.140

Function used was FASTA [36.3.4 Apr, 2011]
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