FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0302, 2390 aa 1>>>pF1KA0302 2390 - 2390 aa - 2390 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.1702+/-0.000549; mu= -7.9050+/- 0.034 mean_var=327.9683+/-68.809, 0's: 0 Z-trim(117.2): 470 B-trim: 480 in 2/51 Lambda= 0.070820 statistics sampled from 28567 (29079) to 28567 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.341), width: 16 Scan time: 27.590 The best scores are: opt bits E(85289) NP_008877 (OMIM: 600224,604985,615386) spectrin be (2390) 15697 1619.8 0 XP_016873666 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_006718734 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_016873667 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_005274250 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_005274249 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_016873663 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_016873665 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_016873664 (OMIM: 600224,604985,615386) PREDICTE (2390) 15689 1618.9 0 XP_006718732 (OMIM: 600224,604985,615386) PREDICTE (2397) 15361 1585.4 0 XP_016860268 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2 0 XP_016860269 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2 0 XP_005264574 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2 0 XP_006712150 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2 0 XP_016860270 (OMIM: 182790) PREDICTED: spectrin be (2364) 9418 978.2 0 NP_003119 (OMIM: 182790) spectrin beta chain, non- (2364) 9418 978.2 0 XP_005264575 (OMIM: 182790) PREDICTED: spectrin be (2351) 9194 955.3 0 NP_842565 (OMIM: 182790) spectrin beta chain, non- (2155) 9162 952.0 0 XP_011543519 (OMIM: 600224,604985,615386) PREDICTE (1432) 8387 872.8 0 XP_011543518 (OMIM: 600224,604985,615386) PREDICTE (1452) 8387 872.8 0 XP_016877102 (OMIM: 182870,616649) PREDICTED: spec (2287) 7755 808.3 0 NP_001020029 (OMIM: 182870,616649) spectrin beta c (2328) 7755 808.3 0 XP_005268080 (OMIM: 182870,616649) PREDICTED: spec (2328) 7755 808.3 0 XP_016877101 (OMIM: 182870,616649) PREDICTED: spec (2328) 7755 808.3 0 NP_000338 (OMIM: 182870,616649) spectrin beta chai (2137) 7724 805.1 0 XP_016877103 (OMIM: 182870,616649) PREDICTED: spec (2137) 7724 805.1 0 XP_011535407 (OMIM: 182870,616649) PREDICTED: spec (1554) 5840 612.6 1.3e-173 XP_016882540 (OMIM: 606214) PREDICTED: spectrin be (2129) 2952 317.6 1.1e-84 XP_011525475 (OMIM: 606214) PREDICTED: spectrin be (2351) 2952 317.6 1.2e-84 NP_066022 (OMIM: 606214) spectrin beta chain, non- (2564) 2952 317.6 1.3e-84 XP_016882538 (OMIM: 606214) PREDICTED: spectrin be (2564) 2952 317.6 1.3e-84 XP_016882541 (OMIM: 606214) PREDICTED: spectrin be (1309) 2890 311.1 5.9e-83 XP_016882539 (OMIM: 606214) PREDICTED: spectrin be (2450) 2525 274.0 1.7e-71 NP_079489 (OMIM: 606214) spectrin beta chain, non- ( 678) 1779 197.5 4.9e-49 XP_016870548 (OMIM: 182810,613477) PREDICTED: spec (2471) 1729 192.6 5.2e-47 NP_003118 (OMIM: 182810,613477) spectrin alpha cha (2472) 1729 192.6 5.2e-47 NP_001123910 (OMIM: 182810,613477) spectrin alpha (2477) 1729 192.6 5.2e-47 XP_006717313 (OMIM: 182810,613477) PREDICTED: spec (2483) 1729 192.6 5.2e-47 XP_006717312 (OMIM: 182810,613477) PREDICTED: spec (2484) 1729 192.6 5.2e-47 XP_006717311 (OMIM: 182810,613477) PREDICTED: spec (2489) 1729 192.6 5.2e-47 XP_006717317 (OMIM: 182810,613477) PREDICTED: spec (2498) 1729 192.6 5.2e-47 XP_006717309 (OMIM: 182810,613477) PREDICTED: spec (2505) 1729 192.6 5.3e-47 XP_006717308 (OMIM: 182810,613477) PREDICTED: spec (2510) 1729 192.6 5.3e-47 XP_016877794 (OMIM: 605916) PREDICTED: spectrin be (1856) 1663 185.8 4.3e-45 NP_001182461 (OMIM: 182810,613477) spectrin alpha (2452) 1664 186.0 5.1e-45 XP_016870550 (OMIM: 182810,613477) PREDICTED: spec (2457) 1664 186.0 5.2e-45 XP_016870549 (OMIM: 182810,613477) PREDICTED: spec (2463) 1664 186.0 5.2e-45 XP_006717316 (OMIM: 182810,613477) PREDICTED: spec (2464) 1664 186.0 5.2e-45 XP_006717315 (OMIM: 182810,613477) PREDICTED: spec (2469) 1664 186.0 5.2e-45 XP_006717314 (OMIM: 182810,613477) PREDICTED: spec (2478) 1664 186.0 5.2e-45 >>NP_008877 (OMIM: 600224,604985,615386) spectrin beta c (2390 aa) initn: 15697 init1: 15697 opt: 15697 Z-score: 8678.1 bits: 1619.8 E(85289): 0 Smith-Waterman score: 15697; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_016873666 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_006718734 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_006 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_016873667 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_005274250 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_005 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_005274249 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_005 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_016873663 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_016873665 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_016873664 (OMIM: 600224,604985,615386) PREDICTED: s (2390 aa) initn: 15689 init1: 15689 opt: 15689 Z-score: 8673.7 bits: 1618.9 E(85289): 0 Smith-Waterman score: 15689; 100.0% identity (100.0% similar) in 2390 aa overlap (1-2390:1-2390) 10 20 30 40 50 60 pF1KA0 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYLMDWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLLASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQAR ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: XP_016 STQALARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQAR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGERARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNTLAAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EANALAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAW 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQC 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEM 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLF 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELAELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLK 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELM 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYA 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPTASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEH 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFPEGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQ 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLAR 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEP 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 pF1KA0 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2350 2360 2370 2380 2390 >>XP_006718732 (OMIM: 600224,604985,615386) PREDICTED: s (2397 aa) initn: 15356 init1: 15356 opt: 15361 Z-score: 8492.6 bits: 1585.4 E(85289): 0 Smith-Waterman score: 15361; 99.4% identity (99.7% similar) in 2356 aa overlap (35-2390:43-2397) 10 20 30 40 50 60 pF1KA0 LSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQKKTFT : .. : ..: .:.: : :::::::::::: XP_006 GLHEASEFYYEAVEGAHNPGGLLLSPAAFINPAQYASVLE-GRFKQLQDEREAVQKKTFT 20 30 40 50 60 70 70 80 90 100 110 120 pF1KA0 KWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQ 80 90 100 110 120 130 130 140 150 160 170 180 pF1KA0 FLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLL 140 150 160 170 180 190 190 200 210 220 230 240 pF1KA0 WCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLA 200 210 220 230 240 250 250 260 270 280 290 300 pF1KA0 EKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAE 260 270 280 290 300 310 310 320 330 340 350 360 pF1KA0 RLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGN 320 330 340 350 360 370 370 380 390 400 410 420 pF1KA0 LEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLE 380 390 400 410 420 430 430 440 450 460 470 480 pF1KA0 QLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAV 440 450 460 470 480 490 490 500 510 520 530 540 pF1KA0 DAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLM 500 510 520 530 540 550 550 560 570 580 590 600 pF1KA0 DWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNPGKEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DWMEEMKGRLQSQDLGRHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNPGKEY 560 570 580 590 600 610 610 620 630 640 650 660 pF1KA0 RPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLL 620 630 640 650 660 670 670 680 690 700 710 720 pF1KA0 ASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASADTGRDLTGALRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAE 680 690 700 710 720 730 730 740 750 760 770 780 pF1KA0 LQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQA 740 750 760 770 780 790 790 800 810 820 830 840 pF1KA0 LARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQGRVPTLERHYEELQARAGER ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_006 LARQHRALEEEIRSHRPTLDALREQAAALPPTLSRTPEVQSRVPTLERHYEELQARAGER 800 810 820 830 840 850 850 860 870 880 890 900 pF1KA0 ARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTL 860 870 880 890 900 910 910 920 930 940 950 960 pF1KA0 AAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAQITAVNDIAEQLLKANPPGKDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYH 920 930 940 950 960 970 970 980 990 1000 1010 1020 pF1KA0 LECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANA 980 990 1000 1010 1020 1030 1030 1040 1050 1060 1070 1080 pF1KA0 LAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAAGHPAQAVAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRT 1040 1050 1060 1070 1080 1090 1090 1100 1110 1120 1130 1140 pF1KA0 QTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQCLFLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQCLFLR 1100 1110 1120 1130 1140 1150 1150 1160 1170 1180 1190 1200 pF1KA0 QRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTL 1160 1170 1180 1190 1200 1210 1210 1220 1230 1240 1250 1260 pF1KA0 QAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQ 1220 1230 1240 1250 1260 1270 1270 1280 1290 1300 1310 1320 pF1KA0 DAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMA 1280 1290 1300 1310 1320 1330 1330 1340 1350 1360 1370 1380 pF1KA0 ELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELAANKDWLDKVDKEGRELTLEKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANR 1340 1350 1360 1370 1380 1390 1390 1400 1410 1420 1430 1440 pF1KA0 AELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQA 1400 1410 1420 1430 1440 1450 1450 1460 1470 1480 1490 1500 pF1KA0 QAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QAKALAQEDQGAGEVERTSRAVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWV 1460 1470 1480 1490 1500 1510 1510 1520 1530 1540 1550 1560 pF1KA0 TERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAGPELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAGPELA 1520 1530 1540 1550 1560 1570 1570 1580 1590 1600 1610 1620 pF1KA0 ELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELQEMWKRLGHELELRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQ 1580 1590 1600 1610 1620 1630 1630 1640 1650 1660 1670 1680 pF1KA0 AEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAG 1640 1650 1660 1670 1680 1690 1690 1700 1710 1720 1730 1740 pF1KA0 ERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTS 1700 1710 1720 1730 1740 1750 1750 1760 1770 1780 1790 1800 pF1KA0 TIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQ 1760 1770 1780 1790 1800 1810 1810 1820 1830 1840 1850 1860 pF1KA0 RFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGH 1820 1830 1840 1850 1860 1870 1870 1880 1890 1900 1910 1920 pF1KA0 RLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMD 1880 1890 1900 1910 1920 1930 1930 1940 1950 1960 1970 1980 pF1KA0 EVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEI 1940 1950 1960 1970 1980 1990 1990 2000 2010 2020 2030 2040 pF1KA0 SEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCT 2000 2010 2020 2030 2040 2050 2050 2060 2070 2080 2090 2100 pF1KA0 VDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPT 2060 2070 2080 2090 2100 2110 2110 2120 2130 2140 2150 2160 pF1KA0 ASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEHSSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASVPPGDLVGGQTASDTTWDGTQPRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEHSSFP 2120 2130 2140 2150 2160 2170 2170 2180 2190 2200 2210 2220 pF1KA0 EGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQMEGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGPGPGSGDEANGPRGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQMEGM 2180 2190 2200 2210 2220 2230 2230 2240 2250 2260 2270 2280 pF1KA0 LCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGS 2240 2250 2260 2270 2280 2290 2290 2300 2310 2320 2330 2340 pF1KA0 VAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPS 2300 2310 2320 2330 2340 2350 2350 2360 2370 2380 2390 pF1KA0 TTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK :::::::::::::::::::::::::::::::::::::::::::::: XP_006 TTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK 2360 2370 2380 2390 2390 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:22:26 2016 done: Sat Nov 5 01:22:30 2016 Total Scan time: 27.590 Total Display time: 2.140 Function used was FASTA [36.3.4 Apr, 2011]