FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0305, 1539 aa 1>>>pF1KA0305 1539 - 1539 aa - 1539 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5761+/-0.000474; mu= 19.0650+/- 0.030 mean_var=129.9950+/-26.716, 0's: 0 Z-trim(111.3): 178 B-trim: 0 in 0/56 Lambda= 0.112489 statistics sampled from 19697 (19881) to 19697 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.233), width: 16 Scan time: 16.190 The best scores are: opt bits E(85289) NP_001098721 (OMIM: 608880) zinc finger FYVE domai (1539) 10109 1653.7 0 NP_055548 (OMIM: 608880) zinc finger FYVE domain-c (1539) 10109 1653.7 0 NP_001271165 (OMIM: 608880) zinc finger FYVE domai (1539) 10109 1653.7 0 XP_016865580 (OMIM: 608880) PREDICTED: zinc finger (1539) 10095 1651.5 0 XP_016865581 (OMIM: 608880) PREDICTED: zinc finger (1539) 10095 1651.5 0 XP_011542055 (OMIM: 608880) PREDICTED: zinc finger (1539) 10095 1651.5 0 XP_005248689 (OMIM: 608880) PREDICTED: zinc finger (1539) 10095 1651.5 0 NP_001271166 (OMIM: 608880) zinc finger FYVE domai ( 809) 5296 872.4 0 XP_016865583 (OMIM: 608880) PREDICTED: zinc finger ( 727) 4769 786.9 0 XP_016865584 (OMIM: 608880) PREDICTED: zinc finger ( 727) 4769 786.9 0 XP_016865582 (OMIM: 608880) PREDICTED: zinc finger ( 727) 4769 786.9 0 XP_016865585 (OMIM: 608880) PREDICTED: zinc finger ( 632) 4123 682.0 4.2e-195 NP_015563 (OMIM: 603755) zinc finger FYVE domain-c (1366) 1962 331.5 2.8e-89 NP_004790 (OMIM: 603755) zinc finger FYVE domain-c (1425) 1962 331.6 2.9e-89 XP_011540739 (OMIM: 603755) PREDICTED: zinc finger (1425) 1962 331.6 2.9e-89 XP_016858334 (OMIM: 603755) PREDICTED: zinc finger (1167) 996 174.7 3.9e-42 NP_060821 (OMIM: 613520) FYVE, RhoGEF and PH domai (1430) 310 63.5 1.5e-08 XP_016880786 (OMIM: 604375) PREDICTED: hepatocyte ( 768) 270 56.7 8.4e-07 XP_011523765 (OMIM: 604375) PREDICTED: hepatocyte ( 777) 270 56.7 8.5e-07 NP_004703 (OMIM: 604375) hepatocyte growth factor- ( 777) 270 56.7 8.5e-07 NP_076976 (OMIM: 613504) zinc finger FYVE domain-c ( 234) 261 54.8 9.6e-07 NP_001185882 (OMIM: 613504) zinc finger FYVE domai ( 252) 261 54.9 1e-06 XP_005257843 (OMIM: 603559) PREDICTED: myotubulari (1195) 263 55.8 2.6e-06 NP_004678 (OMIM: 603559) myotubularin-related prot (1195) 263 55.8 2.6e-06 XP_006722231 (OMIM: 603559) PREDICTED: myotubulari (1195) 263 55.8 2.6e-06 XP_011523762 (OMIM: 603559) PREDICTED: myotubulari (1199) 263 55.8 2.6e-06 XP_005257842 (OMIM: 603559) PREDICTED: myotubulari (1199) 263 55.8 2.6e-06 XP_005257841 (OMIM: 603559) PREDICTED: myotubulari (1209) 263 55.8 2.6e-06 XP_011509086 (OMIM: 121850,609414) PREDICTED: 1-ph (2053) 264 56.1 3.4e-06 XP_011509082 (OMIM: 121850,609414) PREDICTED: 1-ph (2109) 264 56.1 3.5e-06 XP_011509094 (OMIM: 121850,609414) PREDICTED: 1-ph (1340) 259 55.2 4.4e-06 NP_001171471 (OMIM: 121850,609414) 1-phosphatidyli ( 548) 253 53.9 4.4e-06 NP_078789 (OMIM: 607182,610019) FYVE and coiled-co (1478) 259 55.2 4.7e-06 XP_011532413 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 259 55.2 4.7e-06 XP_006713397 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 259 55.2 4.7e-06 XP_006713396 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 259 55.2 4.7e-06 XP_011509087 (OMIM: 121850,609414) PREDICTED: 1-ph (2048) 259 55.3 6e-06 XP_011509085 (OMIM: 121850,609414) PREDICTED: 1-ph (2054) 259 55.3 6e-06 XP_011509084 (OMIM: 121850,609414) PREDICTED: 1-ph (2055) 259 55.3 6e-06 XP_011509083 (OMIM: 121850,609414) PREDICTED: 1-ph (2104) 259 55.3 6.1e-06 XP_011509080 (OMIM: 121850,609414) PREDICTED: 1-ph (2110) 259 55.3 6.1e-06 XP_011509081 (OMIM: 121850,609414) PREDICTED: 1-ph (2110) 259 55.3 6.1e-06 NP_775829 (OMIM: 605091) FYVE, RhoGEF and PH domai ( 655) 250 53.4 7.1e-06 NP_001291413 (OMIM: 609311,611104) FYVE, RhoGEF an ( 422) 245 52.5 9e-06 NP_001291412 (OMIM: 609311,611104) FYVE, RhoGEF an ( 471) 245 52.5 9.7e-06 XP_011518861 (OMIM: 609311,611104) PREDICTED: FYVE ( 511) 245 52.5 1e-05 XP_005253367 (OMIM: 609311,611104) PREDICTED: FYVE ( 518) 245 52.5 1e-05 XP_011518860 (OMIM: 609311,611104) PREDICTED: FYVE ( 567) 245 52.6 1.1e-05 XP_016874294 (OMIM: 609311,611104) PREDICTED: FYVE ( 582) 245 52.6 1.1e-05 XP_011518859 (OMIM: 609311,611104) PREDICTED: FYVE ( 582) 245 52.6 1.1e-05 >>NP_001098721 (OMIM: 608880) zinc finger FYVE domain-co (1539 aa) initn: 10109 init1: 10109 opt: 10109 Z-score: 8868.7 bits: 1653.7 E(85289): 0 Smith-Waterman score: 10109; 99.9% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: NP_001 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>NP_055548 (OMIM: 608880) zinc finger FYVE domain-conta (1539 aa) initn: 10109 init1: 10109 opt: 10109 Z-score: 8868.7 bits: 1653.7 E(85289): 0 Smith-Waterman score: 10109; 99.9% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: NP_055 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>NP_001271165 (OMIM: 608880) zinc finger FYVE domain-co (1539 aa) initn: 10109 init1: 10109 opt: 10109 Z-score: 8868.7 bits: 1653.7 E(85289): 0 Smith-Waterman score: 10109; 99.9% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: NP_001 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>XP_016865580 (OMIM: 608880) PREDICTED: zinc finger FYV (1539 aa) initn: 10095 init1: 10095 opt: 10095 Z-score: 8856.4 bits: 1651.5 E(85289): 0 Smith-Waterman score: 10095; 99.8% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_016 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICEIVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: XP_016 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>XP_016865581 (OMIM: 608880) PREDICTED: zinc finger FYV (1539 aa) initn: 10095 init1: 10095 opt: 10095 Z-score: 8856.4 bits: 1651.5 E(85289): 0 Smith-Waterman score: 10095; 99.8% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_016 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICEIVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: XP_016 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>XP_011542055 (OMIM: 608880) PREDICTED: zinc finger FYV (1539 aa) initn: 10095 init1: 10095 opt: 10095 Z-score: 8856.4 bits: 1651.5 E(85289): 0 Smith-Waterman score: 10095; 99.8% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICEIVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_011 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: XP_011 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>XP_005248689 (OMIM: 608880) PREDICTED: zinc finger FYV (1539 aa) initn: 10095 init1: 10095 opt: 10095 Z-score: 8856.4 bits: 1651.5 E(85289): 0 Smith-Waterman score: 10095; 99.8% identity (99.9% similar) in 1539 aa overlap (1-1539:1-1539) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_005 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICEIVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: XP_005 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA0 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::::: XP_005 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1510 1520 1530 >>NP_001271166 (OMIM: 608880) zinc finger FYVE domain-co (809 aa) initn: 5296 init1: 5296 opt: 5296 Z-score: 4651.0 bits: 872.4 E(85289): 0 Smith-Waterman score: 5296; 99.6% identity (99.9% similar) in 808 aa overlap (1-808:1-808) 10 20 30 40 50 60 pF1KA0 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT ::::::::::::::::::::::::::.. NP_001 CNRKCKLQYLEKEARVCVVCYETISKGEY 790 800 >>XP_016865583 (OMIM: 608880) PREDICTED: zinc finger FYV (727 aa) initn: 4769 init1: 4769 opt: 4769 Z-score: 4189.4 bits: 786.9 E(85289): 0 Smith-Waterman score: 4769; 99.9% identity (100.0% similar) in 727 aa overlap (813-1539:1-727) 790 800 810 820 830 840 pF1KA0 RKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSS :::::::::::::::::::::::::::::: XP_016 MMSPTGSNLKSNHSDECTTVQPPQENQTSS 10 20 30 850 860 870 880 890 900 pF1KA0 IPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPL 40 50 60 70 80 90 910 920 930 940 950 960 pF1KA0 SPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTS 100 110 120 130 140 150 970 980 990 1000 1010 1020 pF1KA0 GSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDEDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDEDSL 160 170 180 190 200 210 1030 1040 1050 1060 1070 1080 pF1KA0 PPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDKYW ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 PPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDKYW 220 230 240 250 260 270 1090 1100 1110 1120 1130 1140 pF1KA0 YFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTES 280 290 300 310 320 330 1150 1160 1170 1180 1190 1200 pF1KA0 FLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYK 340 350 360 370 380 390 1210 1220 1230 1240 1250 1260 pF1KA0 AYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKK 400 410 420 430 440 450 1270 1280 1290 1300 1310 1320 pF1KA0 YSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASFVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASFVV 460 470 480 490 500 510 1330 1340 1350 1360 1370 1380 pF1KA0 FNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYV 520 530 540 550 560 570 1390 1400 1410 1420 1430 1440 pF1KA0 DICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLS 580 590 600 610 620 630 1450 1460 1470 1480 1490 1500 pF1KA0 ILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQH 640 650 660 670 680 690 1510 1520 1530 pF1KA0 YLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::: XP_016 YLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 700 710 720 >>XP_016865584 (OMIM: 608880) PREDICTED: zinc finger FYV (727 aa) initn: 4769 init1: 4769 opt: 4769 Z-score: 4189.4 bits: 786.9 E(85289): 0 Smith-Waterman score: 4769; 99.9% identity (100.0% similar) in 727 aa overlap (813-1539:1-727) 790 800 810 820 830 840 pF1KA0 RKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSS :::::::::::::::::::::::::::::: XP_016 MMSPTGSNLKSNHSDECTTVQPPQENQTSS 10 20 30 850 860 870 880 890 900 pF1KA0 IPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPL 40 50 60 70 80 90 910 920 930 940 950 960 pF1KA0 SPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTS 100 110 120 130 140 150 970 980 990 1000 1010 1020 pF1KA0 GSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDEDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDEDSL 160 170 180 190 200 210 1030 1040 1050 1060 1070 1080 pF1KA0 PPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDKYW ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 PPLLVASGEKGSVPVVEEHPSHEQIILLLEGESFHPVTFVLNANLLVNVKFIFYSSDKYW 220 230 240 250 260 270 1090 1100 1110 1120 1130 1140 pF1KA0 YFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTES 280 290 300 310 320 330 1150 1160 1170 1180 1190 1200 pF1KA0 FLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYK 340 350 360 370 380 390 1210 1220 1230 1240 1250 1260 pF1KA0 AYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKK 400 410 420 430 440 450 1270 1280 1290 1300 1310 1320 pF1KA0 YSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASFVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASFVV 460 470 480 490 500 510 1330 1340 1350 1360 1370 1380 pF1KA0 FNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYV 520 530 540 550 560 570 1390 1400 1410 1420 1430 1440 pF1KA0 DICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLS 580 590 600 610 620 630 1450 1460 1470 1480 1490 1500 pF1KA0 ILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQH 640 650 660 670 680 690 1510 1520 1530 pF1KA0 YLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF ::::::::::::::::::::::::::::::::::::: XP_016 YLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 700 710 720 1539 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:30:47 2016 done: Wed Nov 2 18:30:49 2016 Total Scan time: 16.190 Total Display time: 0.970 Function used was FASTA [36.3.4 Apr, 2011]