FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0308, 2012 aa 1>>>pF1KA0308 2012 - 2012 aa - 2012 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.5842+/-0.000517; mu= -10.8359+/- 0.032 mean_var=332.5653+/-70.533, 0's: 0 Z-trim(117.8): 267 B-trim: 1401 in 1/60 Lambda= 0.070329 statistics sampled from 29789 (30073) to 29789 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.353), width: 16 Scan time: 15.530 The best scores are: opt bits E(85289) XP_016879217 (OMIM: 616936) PREDICTED: chromodomai (2237) 13261 1361.2 0 XP_005256233 (OMIM: 616936) PREDICTED: chromodomai (2391) 13261 1361.2 0 XP_016879215 (OMIM: 616936) PREDICTED: chromodomai (2424) 13261 1361.2 0 XP_016879213 (OMIM: 616936) PREDICTED: chromodomai (2447) 13261 1361.2 0 XP_006721346 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_016879209 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_005256225 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_011521649 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_016879208 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_005256226 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_016879207 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_006721344 (OMIM: 616936) PREDICTED: chromodomai (2898) 13261 1361.2 0 XP_016879210 (OMIM: 616936) PREDICTED: chromodomai (2897) 13244 1359.5 0 NP_001295248 (OMIM: 616936) chromodomain-helicase- (2897) 13244 1359.5 0 XP_016879216 (OMIM: 616936) PREDICTED: chromodomai (2375) 9618 991.6 0 XP_016879214 (OMIM: 616936) PREDICTED: chromodomai (2431) 9618 991.6 0 XP_016879211 (OMIM: 616936) PREDICTED: chromodomai (2882) 9618 991.6 0 NP_079410 (OMIM: 616936) chromodomain-helicase-DNA (2881) 9601 989.9 0 XP_005256229 (OMIM: 616936) PREDICTED: chromodomai (2881) 9601 989.9 0 XP_016879212 (OMIM: 616936) PREDICTED: chromodomai (2881) 9601 989.9 0 XP_011515857 (OMIM: 189960,214800,608892,612370) P (3026) 5362 559.8 1.6e-157 XP_011515856 (OMIM: 189960,214800,608892,612370) P (3027) 5361 559.7 1.7e-157 XP_011515855 (OMIM: 189960,214800,608892,612370) P (3027) 5361 559.7 1.7e-157 XP_016869101 (OMIM: 189960,214800,608892,612370) P (3027) 5361 559.7 1.7e-157 XP_016869102 (OMIM: 189960,214800,608892,612370) P (2996) 4742 496.9 1.4e-138 NP_060250 (OMIM: 189960,214800,608892,612370) chro (2997) 4742 496.9 1.4e-138 NP_065971 (OMIM: 610528,615032) chromodomain-helic (2302) 4722 494.8 4.4e-138 NP_001164100 (OMIM: 610528,615032) chromodomain-he (2581) 4722 494.8 4.9e-138 XP_016883593 (OMIM: 616114) PREDICTED: chromodomai (2378) 4418 464.0 8.8e-129 XP_016883592 (OMIM: 616114) PREDICTED: chromodomai (2381) 4418 464.0 8.8e-129 XP_016883591 (OMIM: 616114) PREDICTED: chromodomai (2424) 4418 464.0 8.9e-129 XP_005260630 (OMIM: 616114) PREDICTED: chromodomai (2693) 4418 464.0 9.8e-129 XP_016883589 (OMIM: 616114) PREDICTED: chromodomai (2693) 4418 464.0 9.8e-129 XP_011527382 (OMIM: 616114) PREDICTED: chromodomai (2713) 4418 464.0 9.9e-129 NP_115597 (OMIM: 616114) chromodomain-helicase-DNA (2715) 4418 464.0 9.9e-129 XP_016883588 (OMIM: 616114) PREDICTED: chromodomai (2716) 4418 464.0 9.9e-129 XP_011515862 (OMIM: 189960,214800,608892,612370) P (1621) 3558 376.6 1.2e-102 XP_016883590 (OMIM: 616114) PREDICTED: chromodomai (2668) 3466 367.4 1.2e-99 XP_011527384 (OMIM: 616114) PREDICTED: chromodomai (2038) 3409 361.6 5e-98 XP_016874223 (OMIM: 603277,617159) PREDICTED: chro (1892) 1464 164.2 1.2e-38 XP_016874222 (OMIM: 603277,617159) PREDICTED: chro (1893) 1464 164.2 1.2e-38 XP_016874221 (OMIM: 603277,617159) PREDICTED: chro (1895) 1464 164.2 1.2e-38 XP_016874220 (OMIM: 603277,617159) PREDICTED: chro (1899) 1464 164.2 1.2e-38 XP_016874219 (OMIM: 603277,617159) PREDICTED: chro (1900) 1464 164.2 1.2e-38 XP_006719025 (OMIM: 603277,617159) PREDICTED: chro (1902) 1464 164.2 1.2e-38 NP_001284482 (OMIM: 603277,617159) chromodomain-he (1905) 1464 164.2 1.2e-38 XP_005253725 (OMIM: 603277,617159) PREDICTED: chro (1905) 1464 164.2 1.2e-38 XP_016874218 (OMIM: 603277,617159) PREDICTED: chro (1906) 1464 164.2 1.2e-38 XP_006719024 (OMIM: 603277,617159) PREDICTED: chro (1908) 1464 164.2 1.2e-38 XP_016874217 (OMIM: 603277,617159) PREDICTED: chro (1911) 1464 164.2 1.2e-38 >>XP_016879217 (OMIM: 616936) PREDICTED: chromodomain-he (2237 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7282.6 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:226-2237) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_016 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 200 210 220 230 240 250 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 260 270 280 290 300 310 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 320 330 340 350 360 370 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 380 390 400 410 420 430 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 440 450 460 470 480 490 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 500 510 520 530 540 550 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 560 570 580 590 600 610 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 620 630 640 650 660 670 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 680 690 700 710 720 730 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 740 750 760 770 780 790 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 800 810 820 830 840 850 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 860 870 880 890 900 910 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 920 930 940 950 960 970 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 980 990 1000 1010 1020 1030 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1040 1050 1060 1070 1080 1090 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1100 1110 1120 1130 1140 1150 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1160 1170 1180 1190 1200 1210 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1220 1230 1240 1250 1260 1270 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1280 1290 1300 1310 1320 1330 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 1340 1350 1360 1370 1380 1390 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 1400 1410 1420 1430 1440 1450 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 1460 1470 1480 1490 1500 1510 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 1520 1530 1540 1550 1560 1570 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 1580 1590 1600 1610 1620 1630 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 1640 1650 1660 1670 1680 1690 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 1700 1710 1720 1730 1740 1750 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 1760 1770 1780 1790 1800 1810 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 1820 1830 1840 1850 1860 1870 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 1880 1890 1900 1910 1920 1930 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 1940 1950 1960 1970 1980 1990 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2000 2010 2020 2030 2040 2050 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2060 2070 2080 2090 2100 2110 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2120 2130 2140 2150 2160 2170 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2180 2190 2200 2210 2220 2230 pF1KA0 ED :: XP_016 ED >>XP_005256233 (OMIM: 616936) PREDICTED: chromodomain-he (2391 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7282.1 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:380-2391) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_005 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 350 360 370 380 390 400 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 410 420 430 440 450 460 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 470 480 490 500 510 520 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 530 540 550 560 570 580 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 590 600 610 620 630 640 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 650 660 670 680 690 700 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 710 720 730 740 750 760 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 770 780 790 800 810 820 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 830 840 850 860 870 880 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 890 900 910 920 930 940 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 950 960 970 980 990 1000 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1010 1020 1030 1040 1050 1060 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1070 1080 1090 1100 1110 1120 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1130 1140 1150 1160 1170 1180 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1190 1200 1210 1220 1230 1240 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1250 1260 1270 1280 1290 1300 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1310 1320 1330 1340 1350 1360 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1370 1380 1390 1400 1410 1420 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1430 1440 1450 1460 1470 1480 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 1490 1500 1510 1520 1530 1540 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 1550 1560 1570 1580 1590 1600 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 1610 1620 1630 1640 1650 1660 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 1670 1680 1690 1700 1710 1720 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 1730 1740 1750 1760 1770 1780 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_005 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 1790 1800 1810 1820 1830 1840 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 1850 1860 1870 1880 1890 1900 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 1910 1920 1930 1940 1950 1960 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 1970 1980 1990 2000 2010 2020 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2030 2040 2050 2060 2070 2080 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2090 2100 2110 2120 2130 2140 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2150 2160 2170 2180 2190 2200 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2210 2220 2230 2240 2250 2260 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2270 2280 2290 2300 2310 2320 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2330 2340 2350 2360 2370 2380 pF1KA0 ED :: XP_005 ED 2390 >>XP_016879215 (OMIM: 616936) PREDICTED: chromodomain-he (2424 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7282.0 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:413-2424) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_016 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 390 400 410 420 430 440 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 450 460 470 480 490 500 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 510 520 530 540 550 560 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 570 580 590 600 610 620 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 630 640 650 660 670 680 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 690 700 710 720 730 740 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 750 760 770 780 790 800 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 810 820 830 840 850 860 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 870 880 890 900 910 920 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 930 940 950 960 970 980 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 990 1000 1010 1020 1030 1040 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1050 1060 1070 1080 1090 1100 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1110 1120 1130 1140 1150 1160 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1170 1180 1190 1200 1210 1220 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1230 1240 1250 1260 1270 1280 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1290 1300 1310 1320 1330 1340 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1350 1360 1370 1380 1390 1400 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1410 1420 1430 1440 1450 1460 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1470 1480 1490 1500 1510 1520 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 1530 1540 1550 1560 1570 1580 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 1590 1600 1610 1620 1630 1640 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 1650 1660 1670 1680 1690 1700 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 1710 1720 1730 1740 1750 1760 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 1770 1780 1790 1800 1810 1820 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 1830 1840 1850 1860 1870 1880 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 1890 1900 1910 1920 1930 1940 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 1950 1960 1970 1980 1990 2000 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2010 2020 2030 2040 2050 2060 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2070 2080 2090 2100 2110 2120 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2130 2140 2150 2160 2170 2180 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2190 2200 2210 2220 2230 2240 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2250 2260 2270 2280 2290 2300 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2310 2320 2330 2340 2350 2360 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2370 2380 2390 2400 2410 2420 pF1KA0 ED :: XP_016 ED >>XP_016879213 (OMIM: 616936) PREDICTED: chromodomain-he (2447 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7282.0 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:436-2447) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_016 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 410 420 430 440 450 460 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 470 480 490 500 510 520 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 530 540 550 560 570 580 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 590 600 610 620 630 640 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 650 660 670 680 690 700 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 710 720 730 740 750 760 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 770 780 790 800 810 820 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 830 840 850 860 870 880 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 890 900 910 920 930 940 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 950 960 970 980 990 1000 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1010 1020 1030 1040 1050 1060 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1070 1080 1090 1100 1110 1120 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1130 1140 1150 1160 1170 1180 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1190 1200 1210 1220 1230 1240 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1250 1260 1270 1280 1290 1300 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1310 1320 1330 1340 1350 1360 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1370 1380 1390 1400 1410 1420 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1430 1440 1450 1460 1470 1480 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1490 1500 1510 1520 1530 1540 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 1550 1560 1570 1580 1590 1600 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 1610 1620 1630 1640 1650 1660 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 1670 1680 1690 1700 1710 1720 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 1730 1740 1750 1760 1770 1780 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 1790 1800 1810 1820 1830 1840 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 1850 1860 1870 1880 1890 1900 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 1910 1920 1930 1940 1950 1960 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 1970 1980 1990 2000 2010 2020 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2030 2040 2050 2060 2070 2080 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2090 2100 2110 2120 2130 2140 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2150 2160 2170 2180 2190 2200 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2210 2220 2230 2240 2250 2260 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2270 2280 2290 2300 2310 2320 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2330 2340 2350 2360 2370 2380 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2390 2400 2410 2420 2430 2440 pF1KA0 ED :: XP_016 ED >>XP_006721346 (OMIM: 616936) PREDICTED: chromodomain-he (2898 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7280.8 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:887-2898) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_006 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 860 870 880 890 900 910 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 920 930 940 950 960 970 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 980 990 1000 1010 1020 1030 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 1040 1050 1060 1070 1080 1090 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 1100 1110 1120 1130 1140 1150 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 1160 1170 1180 1190 1200 1210 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 1220 1230 1240 1250 1260 1270 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 1280 1290 1300 1310 1320 1330 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 1340 1350 1360 1370 1380 1390 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 1400 1410 1420 1430 1440 1450 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1460 1470 1480 1490 1500 1510 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1520 1530 1540 1550 1560 1570 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1580 1590 1600 1610 1620 1630 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1640 1650 1660 1670 1680 1690 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1700 1710 1720 1730 1740 1750 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1760 1770 1780 1790 1800 1810 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1820 1830 1840 1850 1860 1870 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1880 1890 1900 1910 1920 1930 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1940 1950 1960 1970 1980 1990 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 2000 2010 2020 2030 2040 2050 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 2060 2070 2080 2090 2100 2110 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2120 2130 2140 2150 2160 2170 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 2180 2190 2200 2210 2220 2230 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 2240 2250 2260 2270 2280 2290 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_006 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 2300 2310 2320 2330 2340 2350 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 2360 2370 2380 2390 2400 2410 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 2420 2430 2440 2450 2460 2470 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2480 2490 2500 2510 2520 2530 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2540 2550 2560 2570 2580 2590 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2600 2610 2620 2630 2640 2650 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2660 2670 2680 2690 2700 2710 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2720 2730 2740 2750 2760 2770 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2780 2790 2800 2810 2820 2830 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2840 2850 2860 2870 2880 2890 pF1KA0 ED :: XP_006 ED >>XP_016879209 (OMIM: 616936) PREDICTED: chromodomain-he (2898 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7280.8 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:887-2898) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_016 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 860 870 880 890 900 910 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 920 930 940 950 960 970 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 980 990 1000 1010 1020 1030 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 1040 1050 1060 1070 1080 1090 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 1100 1110 1120 1130 1140 1150 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 1160 1170 1180 1190 1200 1210 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 1220 1230 1240 1250 1260 1270 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 1280 1290 1300 1310 1320 1330 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 1340 1350 1360 1370 1380 1390 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 1400 1410 1420 1430 1440 1450 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1460 1470 1480 1490 1500 1510 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1520 1530 1540 1550 1560 1570 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1580 1590 1600 1610 1620 1630 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1640 1650 1660 1670 1680 1690 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1700 1710 1720 1730 1740 1750 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1760 1770 1780 1790 1800 1810 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1820 1830 1840 1850 1860 1870 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1880 1890 1900 1910 1920 1930 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1940 1950 1960 1970 1980 1990 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 2000 2010 2020 2030 2040 2050 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 2060 2070 2080 2090 2100 2110 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2120 2130 2140 2150 2160 2170 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 2180 2190 2200 2210 2220 2230 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 2240 2250 2260 2270 2280 2290 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 2300 2310 2320 2330 2340 2350 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 2360 2370 2380 2390 2400 2410 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 2420 2430 2440 2450 2460 2470 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2480 2490 2500 2510 2520 2530 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2540 2550 2560 2570 2580 2590 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2600 2610 2620 2630 2640 2650 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2660 2670 2680 2690 2700 2710 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2720 2730 2740 2750 2760 2770 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2780 2790 2800 2810 2820 2830 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2840 2850 2860 2870 2880 2890 pF1KA0 ED :: XP_016 ED >>XP_005256225 (OMIM: 616936) PREDICTED: chromodomain-he (2898 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7280.8 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:887-2898) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_005 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 860 870 880 890 900 910 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 920 930 940 950 960 970 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 980 990 1000 1010 1020 1030 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 1040 1050 1060 1070 1080 1090 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 1100 1110 1120 1130 1140 1150 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 1160 1170 1180 1190 1200 1210 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 1220 1230 1240 1250 1260 1270 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 1280 1290 1300 1310 1320 1330 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 1340 1350 1360 1370 1380 1390 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 1400 1410 1420 1430 1440 1450 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1460 1470 1480 1490 1500 1510 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1520 1530 1540 1550 1560 1570 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1580 1590 1600 1610 1620 1630 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1640 1650 1660 1670 1680 1690 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1700 1710 1720 1730 1740 1750 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1760 1770 1780 1790 1800 1810 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1820 1830 1840 1850 1860 1870 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1880 1890 1900 1910 1920 1930 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1940 1950 1960 1970 1980 1990 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 2000 2010 2020 2030 2040 2050 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 2060 2070 2080 2090 2100 2110 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2120 2130 2140 2150 2160 2170 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 2180 2190 2200 2210 2220 2230 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 2240 2250 2260 2270 2280 2290 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_005 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 2300 2310 2320 2330 2340 2350 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 2360 2370 2380 2390 2400 2410 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 2420 2430 2440 2450 2460 2470 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2480 2490 2500 2510 2520 2530 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2540 2550 2560 2570 2580 2590 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2600 2610 2620 2630 2640 2650 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2660 2670 2680 2690 2700 2710 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2720 2730 2740 2750 2760 2770 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2780 2790 2800 2810 2820 2830 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2840 2850 2860 2870 2880 2890 pF1KA0 ED :: XP_005 ED >>XP_011521649 (OMIM: 616936) PREDICTED: chromodomain-he (2898 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7280.8 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:887-2898) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_011 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 860 870 880 890 900 910 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 920 930 940 950 960 970 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 980 990 1000 1010 1020 1030 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 1040 1050 1060 1070 1080 1090 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 1100 1110 1120 1130 1140 1150 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 1160 1170 1180 1190 1200 1210 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 1220 1230 1240 1250 1260 1270 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 1280 1290 1300 1310 1320 1330 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 1340 1350 1360 1370 1380 1390 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 1400 1410 1420 1430 1440 1450 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1460 1470 1480 1490 1500 1510 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1520 1530 1540 1550 1560 1570 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1580 1590 1600 1610 1620 1630 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1640 1650 1660 1670 1680 1690 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1700 1710 1720 1730 1740 1750 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1760 1770 1780 1790 1800 1810 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1820 1830 1840 1850 1860 1870 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1880 1890 1900 1910 1920 1930 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1940 1950 1960 1970 1980 1990 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 2000 2010 2020 2030 2040 2050 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 2060 2070 2080 2090 2100 2110 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2120 2130 2140 2150 2160 2170 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 2180 2190 2200 2210 2220 2230 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 2240 2250 2260 2270 2280 2290 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_011 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 2300 2310 2320 2330 2340 2350 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 2360 2370 2380 2390 2400 2410 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 2420 2430 2440 2450 2460 2470 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2480 2490 2500 2510 2520 2530 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2540 2550 2560 2570 2580 2590 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2600 2610 2620 2630 2640 2650 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2660 2670 2680 2690 2700 2710 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2720 2730 2740 2750 2760 2770 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2780 2790 2800 2810 2820 2830 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2840 2850 2860 2870 2880 2890 pF1KA0 ED :: XP_011 ED >>XP_016879208 (OMIM: 616936) PREDICTED: chromodomain-he (2898 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7280.8 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:887-2898) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_016 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 860 870 880 890 900 910 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 920 930 940 950 960 970 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 980 990 1000 1010 1020 1030 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 1040 1050 1060 1070 1080 1090 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 1100 1110 1120 1130 1140 1150 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 1160 1170 1180 1190 1200 1210 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 1220 1230 1240 1250 1260 1270 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 1280 1290 1300 1310 1320 1330 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 1340 1350 1360 1370 1380 1390 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 1400 1410 1420 1430 1440 1450 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1460 1470 1480 1490 1500 1510 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1520 1530 1540 1550 1560 1570 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1580 1590 1600 1610 1620 1630 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1640 1650 1660 1670 1680 1690 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1700 1710 1720 1730 1740 1750 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1760 1770 1780 1790 1800 1810 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1820 1830 1840 1850 1860 1870 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1880 1890 1900 1910 1920 1930 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1940 1950 1960 1970 1980 1990 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 2000 2010 2020 2030 2040 2050 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 2060 2070 2080 2090 2100 2110 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2120 2130 2140 2150 2160 2170 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 2180 2190 2200 2210 2220 2230 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 2240 2250 2260 2270 2280 2290 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 2300 2310 2320 2330 2340 2350 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 2360 2370 2380 2390 2400 2410 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 2420 2430 2440 2450 2460 2470 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2480 2490 2500 2510 2520 2530 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2540 2550 2560 2570 2580 2590 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2600 2610 2620 2630 2640 2650 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2660 2670 2680 2690 2700 2710 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2720 2730 2740 2750 2760 2770 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2780 2790 2800 2810 2820 2830 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2840 2850 2860 2870 2880 2890 pF1KA0 ED :: XP_016 ED >>XP_005256226 (OMIM: 616936) PREDICTED: chromodomain-he (2898 aa) initn: 13261 init1: 13261 opt: 13261 Z-score: 7280.8 bits: 1361.2 E(85289): 0 Smith-Waterman score: 13261; 100.0% identity (100.0% similar) in 2012 aa overlap (1-2012:887-2898) 10 20 30 pF1KA0 MGLGKTIQSITFLYEILLTGIRGPFLIIAP :::::::::::::::::::::::::::::: XP_005 GNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLTGIRGPFLIIAP 860 870 880 890 900 910 40 50 60 70 80 90 pF1KA0 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTF 920 930 940 950 960 970 100 110 120 130 140 150 pF1KA0 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEEL 980 990 1000 1010 1020 1030 160 170 180 190 200 210 pF1KA0 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEET 1040 1050 1060 1070 1080 1090 220 230 240 250 260 270 pF1KA0 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEK 1100 1110 1120 1130 1140 1150 280 290 300 310 320 330 pF1KA0 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILED 1160 1170 1180 1190 1200 1210 340 350 360 370 380 390 pF1KA0 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIF 1220 1230 1240 1250 1260 1270 400 410 420 430 440 450 pF1KA0 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSG 1280 1290 1300 1310 1320 1330 460 470 480 490 500 510 pF1KA0 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RESNVGGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEG 1340 1350 1360 1370 1380 1390 520 530 540 550 560 570 pF1KA0 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIEAISGRNSLVIDTPRIRKQTRP 1400 1410 1420 1430 1440 1450 580 590 600 610 620 630 pF1KA0 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSATKDELAELSEAESEGDEKPKLRRPCDRSNGYGRTECFRVEKNLLVYGWGRWREILSH 1460 1470 1480 1490 1500 1510 640 650 660 670 680 690 pF1KA0 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQNHLGLSA 1520 1530 1540 1550 1560 1570 700 710 720 730 740 750 pF1KA0 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYY 1580 1590 1600 1610 1620 1630 760 770 780 790 800 810 pF1KA0 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKYN 1640 1650 1660 1670 1680 1690 820 830 840 850 860 870 pF1KA0 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDVSSPG 1700 1710 1720 1730 1740 1750 880 890 900 910 920 930 pF1KA0 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLVIADGDGQLMEGDKVYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQPTFSVPTSVMQ 1760 1770 1780 1790 1800 1810 940 950 960 970 980 990 pF1KA0 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PIYEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPDRGQFDWTKFRAMARLH 1820 1830 1840 1850 1860 1870 1000 1010 1020 1030 1040 1050 pF1KA0 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKTDDSLEKYLYAFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVRE 1880 1890 1900 1910 1920 1930 1060 1070 1080 1090 1100 1110 pF1KA0 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QALRHPQLFERLKLCHPNPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMA 1940 1950 1960 1970 1980 1990 1120 1130 1140 1150 1160 1170 pF1KA0 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQRNYSQSKMAHSRTSTPLLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEP 2000 2010 2020 2030 2040 2050 1180 1190 1200 1210 1220 1230 pF1KA0 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAARTEPLTPNP 2060 2070 2080 2090 2100 2110 1240 1250 1260 1270 1280 1290 pF1KA0 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASS 2120 2130 2140 2150 2160 2170 1300 1310 1320 1330 1340 1350 pF1KA0 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSSSSTSSSSSSSSSSSEESDSDEEEAQKRAESTTHMKAYDEESVASLSTTQDETQDSFQ 2180 2190 2200 2210 2220 2230 1360 1370 1380 1390 1400 1410 pF1KA0 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWPSARRSYDANTVASF 2240 2250 2260 2270 2280 2290 1420 1430 1440 1450 1460 1470 pF1KA0 YTTKLLDSPGAATEYSEPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_005 YTTKLLDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKVKKHVREKEFTVKIKDEGGL 2300 2310 2320 2330 2340 2350 1480 1490 1500 1510 1520 1530 pF1KA0 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLTFQKQGLAQKRPFDGEDGALGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTL 2360 2370 2380 2390 2400 2410 1540 1550 1560 1570 1580 1590 pF1KA0 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GANGVILDNQPIVKKRRGRRKNVEGVDIFFFNRNKPPNHVSLGLTSSQISTGINPALSYT 2420 2430 2440 2450 2460 2470 1600 1610 1620 1630 1640 1650 pF1KA0 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPQGIPDTESPVPVINLKDGTRLAGDDAPKRKDLEKWLKEHPGYVEDLGAFIPRMQLHEG 2480 2490 2500 2510 2520 2530 1660 1670 1680 1690 1700 1710 pF1KA0 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGV 2540 2550 2560 2570 2580 2590 1720 1730 1740 1750 1760 1770 pF1KA0 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APEWGDVVKQSGFLPESMYERILTGPVVREEVSRRGRRPKSGIAKATAAAAAASATSVSG 2600 2610 2620 2630 2640 2650 1780 1790 1800 1810 1820 1830 pF1KA0 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAGLMGMPTGLPSGGEAKNMAAMFPMLL 2660 2670 2680 2690 2700 2710 1840 1850 1860 1870 1880 1890 pF1KA0 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGMAGLPNLLGMGGLLTKPTESGTEDKKGSDSKESEGKTERTESQSSENGGENSVSSSPS 2720 2730 2740 2750 2760 2770 1900 1910 1920 1930 1940 1950 pF1KA0 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSSTAALNTAAAANPLALNPLLLSNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLG 2780 2790 2800 2810 2820 2830 1960 1970 1980 1990 2000 2010 pF1KA0 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSN 2840 2850 2860 2870 2880 2890 pF1KA0 ED :: XP_005 ED 2012 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:14:49 2016 done: Sat Nov 5 01:14:51 2016 Total Scan time: 15.530 Total Display time: 1.350 Function used was FASTA [36.3.4 Apr, 2011]