FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0310, 2357 aa 1>>>pF1KA0310 2357 - 2357 aa - 2357 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.2985+/-0.00111; mu= -4.4243+/- 0.067 mean_var=452.9006+/-94.418, 0's: 0 Z-trim(115.0): 50 B-trim: 151 in 1/52 Lambda= 0.060266 statistics sampled from 15570 (15603) to 15570 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.479), width: 16 Scan time: 8.020 The best scores are: opt bits E(32554) CCDS55351.1 SEC16A gene_id:9919|Hs108|chr9 (2357) 16329 1436.1 0 CCDS75936.1 SEC16A gene_id:9919|Hs108|chr9 (2334) 15507 1364.6 0 CCDS44281.1 SEC16B gene_id:89866|Hs108|chr1 (1060) 1650 159.5 7.6e-38 >>CCDS55351.1 SEC16A gene_id:9919|Hs108|chr9 (2357 aa) initn: 16329 init1: 16329 opt: 16329 Z-score: 7685.8 bits: 1436.1 E(32554): 0 Smith-Waterman score: 16329; 100.0% identity (100.0% similar) in 2357 aa overlap (1-2357:1-2357) 10 20 30 40 50 60 pF1KA0 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 LPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSS 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 RPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATS 2290 2300 2310 2320 2330 2340 2350 pF1KA0 GSSRLGRIGQRKHLVLN ::::::::::::::::: CCDS55 GSSRLGRIGQRKHLVLN 2350 >>CCDS75936.1 SEC16A gene_id:9919|Hs108|chr9 (2334 aa) initn: 15802 init1: 15482 opt: 15507 Z-score: 7299.6 bits: 1364.6 E(32554): 0 Smith-Waterman score: 15887; 97.2% identity (97.2% similar) in 2379 aa overlap (1-2357:1-2334) 10 20 30 40 50 60 pF1KA0 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP 2170 2180 2190 2200 2210 2220 2230 2240 2250 pF1KA0 LPIPSNLFVPTP----------------------DAEEPQLPDGTGREGPAAARGLANPE :::::::::::: :::::::::::::::::::::::::: CCDS75 LPIPSNLFVPTPVSSVRPQGRSGRNDGLLALSSPDAEEPQLPDGTGREGPAAARGLANPE 2230 2240 2250 2260 2270 2280 2260 2270 2280 2290 2300 2310 pF1KA0 PAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAG :::::: ::::::::: CCDS75 PAPEPK---------------------------------------------APGDLPAAG 2290 2320 2330 2340 2350 pF1KA0 GPPSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN ::::::::::::::::::::::::::::::::::::::: CCDS75 GPPSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN 2300 2310 2320 2330 >>CCDS44281.1 SEC16B gene_id:89866|Hs108|chr1 (1060 aa) initn: 1475 init1: 1033 opt: 1650 Z-score: 792.9 bits: 159.5 E(32554): 7.6e-38 Smith-Waterman score: 1748; 33.7% identity (59.6% similar) in 1111 aa overlap (1194-2248:3-1047) 1170 1180 1190 1200 1210 pF1KA0 PLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYD-GAASAYAQN----YRYPEP :. :. : : :.: ... .: CCDS44 MELWAPQRLPQTRGKATAPSKDPDRGFRRDGH 10 20 30 1220 1230 1240 1250 pF1KA0 ERPSSRASHSSER----------PPPRQ-----GYPEGYYSSKSG-WS---SQSDYYASY .:: .. :..:: : :.: . .:.:. : : : ::: . CCDS44 HRPVPHSWHNGERFHQWQDNRGSPQPQQEPRADHQQQPHYASRPGDWHQPVSGVDYYEGG 40 50 60 70 80 90 1260 1270 1280 1290 1300 1310 pF1KA0 YSSQYDYGDPGHWDRY--HYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNN : .: :. ::. . : . : .:. .: :. . . .:. . :..:. CCDS44 YRNQL-YSRPGYENSYQSYQSPTMREEYAYGSYYYHG--HPQWLQEERV----PRQRSPY 100 110 120 130 140 1320 1330 1340 1350 1360 1370 pF1KA0 -WRYDPRFTGSFDDDP-DPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSH :. : : .:. . ...:.: . . .: . ..:. : :: :.. CCDS44 IWHEDYREQKYLDEHHYENQHSPFGTNSE---THFQSNSRN-PCKDSPASN----SGQEW 150 160 170 180 190 1380 1390 1400 1410 1420 pF1KA0 QSQIYRSHNVAAGSYEAP--LPPGSFHGDFAYGTYRSNFSSGPGF---PEYGYP-ADTVW .... . .: .. . : ... . : :.. . . :: : :...: CCDS44 PGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIRDAPERDDPPASAAW 200 210 220 230 240 250 1430 1440 1450 1460 1470 1480 pF1KA0 -PAMEQVSSR-PTSPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQH :.. .::: : .: :: .::: . :::::::..: :. :..:: ::::.::::..:. CCDS44 SPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTDGQAALVELHSMEVILND 260 270 280 290 300 310 1490 1500 1510 1520 1530 1540 pF1KA0 TSEQEEMRAFPGPLAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQ . ::::::.: ::: ..:.::::...: :.:: . ..:.: ...:: :::...:::::: CCDS44 SEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKSETLGSRDSA-LLWQLLVLLCRQ 320 330 340 350 360 370 1550 1560 1570 1580 1590 1600 pF1KA0 NGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGP ::..::.::::::..: . . ..: ::::..:.: . :: .: ::: CCDS44 NGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLS---SGTPNL--LTGEI 380 390 400 410 420 430 1610 1620 1630 1640 1650 1660 pF1KA0 AAAASSLERETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN .. . . .:.: .:: :::::.::: :::: ::::::.:.:::: .:.. ::. :.. CCDS44 PPSVETPAQIVEKFTRLLYYGRKKEALEWAMKNHLWGHALFLSSKMDPQTYSWVMSGFTS 440 450 460 470 480 490 1670 1680 1690 1700 1710 1720 pF1KA0 SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMG .: .::::::..::::::.: :.::::...:::::::::..::: .. .. .:.....: CCDS44 TLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILSNQAGDPELYQRAIVAIG 500 510 520 530 540 550 1730 1740 1750 1760 1770 1780 pF1KA0 DTLASRGLLDAAHFCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYE ::::..::..:::::::::.. :: :: :: .:::.::.:: ::::::.::::::: .: CCDS44 DTLAGKGLVEAAHFCYLMAHVPFGHYTVKTDHLVLLGSSHSQEFLKFATTEAIQRTEIFE 560 570 580 590 600 610 1790 1800 1810 1820 1830 1840 pF1KA0 YAQSLGAETCPLPSFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQ : : :: .:::::.:..:. :::..::..::.::::::. ..:.: . :::. . CCDS44 YCQMLGRPKSFIPSFQVYKLLYASRLADYGLVSQALHYCEAIGAAVLSQGESSHPVLLVE 620 630 640 650 660 670 1850 1860 1870 1880 1890 1900 pF1KA0 LVQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQ-QVERQIKEGAGVWHQDGALPQQCPG :...: .:.: :: . :. . : ::..:. :.:... : : . . : CCDS44 LIKLAEKLKLSDPLVLERRSGDRDLEPDWLAQLRRQLEQKVAGDIGDPHPTRSDISGAGG 680 690 700 710 720 730 1910 1920 1930 1940 1950 pF1KA0 TPSSEMEQLDRPGLS----QPG---ALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPD : . . : : . :: :: .. . :::.. : .: : . : CCDS44 TTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQ--P----FPLQPGSYPA 740 750 760 770 780 1960 1970 1980 1990 2000 2010 pF1KA0 GPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQE : :. . .: :. : :: : ... : .: . ...:: CCDS44 GGGAGQTGTPR---PFYSVPETHLPG---TGSSVAVTEATGGTV---------WEEMLQT 790 800 810 820 830 2020 2030 2040 2050 2060 2070 pF1KA0 ARSPDPGIVPQEA---PVGNSLSELSEENFDGKFANLTPSRTVPDSE-APPGWDRADSGP .: . : ::. : :. . . . .. ... : . .: . :.::.. CCDS44 HLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKN- 840 850 860 870 880 2080 2090 2100 2110 2120 2130 pF1KA0 TQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDE :: ..: :. . . . ..: .:: :. .: : :: : . :: CCDS44 -------SPRNTAQR-GKLGDGKEHTKSSGFGWF-SWFRSK-------PT-KNASPAGDE 890 900 910 920 930 2140 2150 2160 2170 2180 2190 pF1KA0 KKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVD .. . . :: .: : ... .. .: . :: :. .:: .: ..: CCDS44 DSS---DSPDSEETPRASSPHQAGLGLSLTPSPES---PPLPDVSAFSRGRGGGEGRGSA 940 950 960 970 980 2200 2210 2220 2230 2240 pF1KA0 VLNPSGTQRSEPALAPADFVA------PLAPLPIPS-NLFVPTPDAEE-PQLPDGTGREG . ... . .:. . :. : . :: :. . :: . . :::: .:. . CCDS44 SSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPPPALKGAVPLYNPSQVPQLPTATSLNR 990 1000 1010 1020 1030 1040 2250 2260 2270 2280 2290 2300 pF1KA0 PAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHF : CCDS44 PNRLAQRRYPTQPC 1050 1060 2357 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:31:48 2016 done: Wed Nov 2 18:31:49 2016 Total Scan time: 8.020 Total Display time: 0.570 Function used was FASTA [36.3.4 Apr, 2011]