FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0311, 2319 aa 1>>>pF1KA0311 2319 - 2319 aa - 2319 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9157+/-0.000512; mu= 7.2235+/- 0.032 mean_var=162.7218+/-32.312, 0's: 0 Z-trim(112.6): 62 B-trim: 51 in 2/54 Lambda= 0.100543 statistics sampled from 21572 (21630) to 21572 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.254), width: 16 Scan time: 20.450 The best scores are: opt bits E(85289) NP_004265 (OMIM: 604691) A-kinase anchor protein 6 (2319) 15178 2215.7 0 XP_016877297 (OMIM: 604691) PREDICTED: A-kinase an (2320) 15166 2214.0 0 XP_016877299 (OMIM: 604691) PREDICTED: A-kinase an (2078) 13585 1984.6 0 XP_016877298 (OMIM: 604691) PREDICTED: A-kinase an (2078) 13585 1984.6 0 XP_011535680 (OMIM: 604691) PREDICTED: A-kinase an (1415) 9247 1355.3 0 XP_016877300 (OMIM: 604691) PREDICTED: A-kinase an (1415) 9247 1355.3 0 XP_011535681 (OMIM: 604691) PREDICTED: A-kinase an (1392) 9137 1339.4 0 XP_011535685 (OMIM: 604691) PREDICTED: A-kinase an (1314) 8622 1264.7 0 NP_001306029 (OMIM: 616889) centrosomal protein of ( 757) 257 51.2 5.7e-05 NP_055962 (OMIM: 616889) centrosomal protein of 68 ( 757) 257 51.2 5.7e-05 NP_001306030 (OMIM: 616889) centrosomal protein of ( 620) 223 46.3 0.0015 >>NP_004265 (OMIM: 604691) A-kinase anchor protein 6 [Ho (2319 aa) initn: 15178 init1: 15178 opt: 15178 Z-score: 11899.4 bits: 2215.7 E(85289): 0 Smith-Waterman score: 15178; 100.0% identity (100.0% similar) in 2319 aa overlap (1-2319:1-2319) 10 20 30 40 50 60 pF1KA0 MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMKDMDSDQQYEKPPPLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMKDMDSDQQYEKPPPLHT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 GDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 MSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 IEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 LSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 IEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 EEGHQLLELIASHKAGLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EEGHQLLELIASHKAGLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSNG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 LLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 RQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 LRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 VIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 YDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 TKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEM 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 CLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 GDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLR 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 GFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLS 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 LLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 SSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSI 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 NEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVNV 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 SCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKN 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 ELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENN 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 GNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSENL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 GSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPT 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 EKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCCN 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 CEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHR 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEACV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEACV 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 EGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQE 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 RAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQDL 2230 2240 2250 2260 2270 2280 2290 2300 2310 pF1KA0 SLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR ::::::::::::::::::::::::::::::::::::::: NP_004 SLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR 2290 2300 2310 >>XP_016877297 (OMIM: 604691) PREDICTED: A-kinase anchor (2320 aa) initn: 9607 init1: 9607 opt: 15166 Z-score: 11890.0 bits: 2214.0 E(85289): 0 Smith-Waterman score: 15166; 100.0% identity (100.0% similar) in 2320 aa overlap (1-2319:1-2320) 10 20 30 40 50 60 pF1KA0 MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMKDMDSDQQYEKPPPLHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMKDMDSDQQYEKPPPLHT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 GDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 MSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 IEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 HKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 ETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 LSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 IEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVE 790 800 810 820 830 840 850 860 870 880 890 pF1KA0 EEGHQLLELIASHKA-GLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVS ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_016 EEGHQLLELIASHKAEGLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVS 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA0 VEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSN 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA0 GLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSK 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA0 VEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSL 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA0 VRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVAS 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA0 ILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KA0 NVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDP 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KA0 GYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNV 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KA0 LTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSE 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KA0 MCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGK 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KA0 VGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLL 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KA0 RGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQL 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KA0 SLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDIS 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KA0 VSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASS 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KA0 INEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVN 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KA0 VSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIK 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KA0 NELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSEN 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 NGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSEN 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 LGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTP 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 TEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCC 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 NCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSH 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 2140 2150 pF1KA0 RPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEAC 2110 2120 2130 2140 2150 2160 2160 2170 2180 2190 2200 2210 pF1KA0 VEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQ 2170 2180 2190 2200 2210 2220 2220 2230 2240 2250 2260 2270 pF1KA0 ERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQD 2230 2240 2250 2260 2270 2280 2280 2290 2300 2310 pF1KA0 LSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR :::::::::::::::::::::::::::::::::::::::: XP_016 LSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR 2290 2300 2310 2320 >>XP_016877299 (OMIM: 604691) PREDICTED: A-kinase anchor (2078 aa) initn: 9607 init1: 9607 opt: 13585 Z-score: 10651.3 bits: 1984.6 E(85289): 0 Smith-Waterman score: 13585; 100.0% identity (100.0% similar) in 2078 aa overlap (243-2319:1-2078) 220 230 240 250 260 270 pF1KA0 QNYLSLDCGITAFELSDYSPSEDLLSGLGDMTSSQVKTKPFDSWSYSEMEKEFPELIRSV :::::::::::::::::::::::::::::: XP_016 MTSSQVKTKPFDSWSYSEMEKEFPELIRSV 10 20 30 280 290 300 310 320 330 pF1KA0 GLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEA 40 50 60 70 80 90 340 350 360 370 380 390 pF1KA0 LTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKR 100 110 120 130 140 150 400 410 420 430 440 450 pF1KA0 GLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAA 160 170 180 190 200 210 460 470 480 490 500 510 pF1KA0 SQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPK 220 230 240 250 260 270 520 530 540 550 560 570 pF1KA0 RGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSET 280 290 300 310 320 330 580 590 600 610 620 630 pF1KA0 SSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLA 340 350 360 370 380 390 640 650 660 670 680 690 pF1KA0 LPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTR 400 410 420 430 440 450 700 710 720 730 740 750 pF1KA0 LGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNES 460 470 480 490 500 510 760 770 780 790 800 810 pF1KA0 HSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEM 520 530 540 550 560 570 820 830 840 850 860 870 pF1KA0 DDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKA-GLKDMLRMIASQWKEL ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_016 DDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAEGLKDMLRMIASQWKEL 580 590 600 610 620 630 880 890 900 910 920 930 pF1KA0 QRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLK 640 650 660 670 680 690 940 950 960 970 980 990 pF1KA0 LYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMS 700 710 720 730 740 750 1000 1010 1020 1030 1040 1050 pF1KA0 EEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKT 760 770 780 790 800 810 1060 1070 1080 1090 1100 1110 pF1KA0 LGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKE 820 830 840 850 860 870 1120 1130 1140 1150 1160 1170 pF1KA0 GTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLE 880 890 900 910 920 930 1180 1190 1200 1210 1220 1230 pF1KA0 RRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISL 940 950 960 970 980 990 1240 1250 1260 1270 1280 1290 pF1KA0 NEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSL 1000 1010 1020 1030 1040 1050 1300 1310 1320 1330 1340 1350 pF1KA0 HNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCAC 1060 1070 1080 1090 1100 1110 1360 1370 1380 1390 1400 1410 pF1KA0 HGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQ 1120 1130 1140 1150 1160 1170 1420 1430 1440 1450 1460 1470 pF1KA0 KFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYS 1180 1190 1200 1210 1220 1230 1480 1490 1500 1510 1520 1530 pF1KA0 YLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILAS 1240 1250 1260 1270 1280 1290 1540 1550 1560 1570 1580 1590 pF1KA0 ASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQ 1300 1310 1320 1330 1340 1350 1600 1610 1620 1630 1640 1650 pF1KA0 RSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIK 1360 1370 1380 1390 1400 1410 1660 1670 1680 1690 1700 1710 pF1KA0 RSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKI 1420 1430 1440 1450 1460 1470 1720 1730 1740 1750 1760 1770 pF1KA0 PESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIK 1480 1490 1500 1510 1520 1530 1780 1790 1800 1810 1820 1830 pF1KA0 DEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDI 1540 1550 1560 1570 1580 1590 1840 1850 1860 1870 1880 1890 pF1KA0 SSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYV 1600 1610 1620 1630 1640 1650 1900 1910 1920 1930 1940 1950 pF1KA0 ADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKE 1660 1670 1680 1690 1700 1710 1960 1970 1980 1990 2000 2010 pF1KA0 FVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSM 1720 1730 1740 1750 1760 1770 2020 2030 2040 2050 2060 2070 pF1KA0 AGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTAL 1780 1790 1800 1810 1820 1830 2080 2090 2100 2110 2120 2130 pF1KA0 KSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEE 1840 1850 1860 1870 1880 1890 2140 2150 2160 2170 2180 2190 pF1KA0 KSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQA 1900 1910 1920 1930 1940 1950 2200 2210 2220 2230 2240 2250 pF1KA0 TACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDS 1960 1970 1980 1990 2000 2010 2260 2270 2280 2290 2300 2310 pF1KA0 EKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHE 2020 2030 2040 2050 2060 2070 pF1KA0 KRHRNMHR :::::::: XP_016 KRHRNMHR >>XP_016877298 (OMIM: 604691) PREDICTED: A-kinase anchor (2078 aa) initn: 9607 init1: 9607 opt: 13585 Z-score: 10651.3 bits: 1984.6 E(85289): 0 Smith-Waterman score: 13585; 100.0% identity (100.0% similar) in 2078 aa overlap (243-2319:1-2078) 220 230 240 250 260 270 pF1KA0 QNYLSLDCGITAFELSDYSPSEDLLSGLGDMTSSQVKTKPFDSWSYSEMEKEFPELIRSV :::::::::::::::::::::::::::::: XP_016 MTSSQVKTKPFDSWSYSEMEKEFPELIRSV 10 20 30 280 290 300 310 320 330 pF1KA0 GLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEA 40 50 60 70 80 90 340 350 360 370 380 390 pF1KA0 LTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKR 100 110 120 130 140 150 400 410 420 430 440 450 pF1KA0 GLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAA 160 170 180 190 200 210 460 470 480 490 500 510 pF1KA0 SQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPK 220 230 240 250 260 270 520 530 540 550 560 570 pF1KA0 RGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSET 280 290 300 310 320 330 580 590 600 610 620 630 pF1KA0 SSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLA 340 350 360 370 380 390 640 650 660 670 680 690 pF1KA0 LPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTR 400 410 420 430 440 450 700 710 720 730 740 750 pF1KA0 LGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNES 460 470 480 490 500 510 760 770 780 790 800 810 pF1KA0 HSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEM 520 530 540 550 560 570 820 830 840 850 860 870 pF1KA0 DDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKA-GLKDMLRMIASQWKEL ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: XP_016 DDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAEGLKDMLRMIASQWKEL 580 590 600 610 620 630 880 890 900 910 920 930 pF1KA0 QRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLK 640 650 660 670 680 690 940 950 960 970 980 990 pF1KA0 LYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMS 700 710 720 730 740 750 1000 1010 1020 1030 1040 1050 pF1KA0 EEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKT 760 770 780 790 800 810 1060 1070 1080 1090 1100 1110 pF1KA0 LGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKE 820 830 840 850 860 870 1120 1130 1140 1150 1160 1170 pF1KA0 GTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLE 880 890 900 910 920 930 1180 1190 1200 1210 1220 1230 pF1KA0 RRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISL 940 950 960 970 980 990 1240 1250 1260 1270 1280 1290 pF1KA0 NEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSL 1000 1010 1020 1030 1040 1050 1300 1310 1320 1330 1340 1350 pF1KA0 HNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCAC 1060 1070 1080 1090 1100 1110 1360 1370 1380 1390 1400 1410 pF1KA0 HGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQ 1120 1130 1140 1150 1160 1170 1420 1430 1440 1450 1460 1470 pF1KA0 KFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYS 1180 1190 1200 1210 1220 1230 1480 1490 1500 1510 1520 1530 pF1KA0 YLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILAS 1240 1250 1260 1270 1280 1290 1540 1550 1560 1570 1580 1590 pF1KA0 ASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQ 1300 1310 1320 1330 1340 1350 1600 1610 1620 1630 1640 1650 pF1KA0 RSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIK 1360 1370 1380 1390 1400 1410 1660 1670 1680 1690 1700 1710 pF1KA0 RSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKI 1420 1430 1440 1450 1460 1470 1720 1730 1740 1750 1760 1770 pF1KA0 PESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIK 1480 1490 1500 1510 1520 1530 1780 1790 1800 1810 1820 1830 pF1KA0 DEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDI 1540 1550 1560 1570 1580 1590 1840 1850 1860 1870 1880 1890 pF1KA0 SSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYV 1600 1610 1620 1630 1640 1650 1900 1910 1920 1930 1940 1950 pF1KA0 ADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKE 1660 1670 1680 1690 1700 1710 1960 1970 1980 1990 2000 2010 pF1KA0 FVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSM 1720 1730 1740 1750 1760 1770 2020 2030 2040 2050 2060 2070 pF1KA0 AGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTAL 1780 1790 1800 1810 1820 1830 2080 2090 2100 2110 2120 2130 pF1KA0 KSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEE 1840 1850 1860 1870 1880 1890 2140 2150 2160 2170 2180 2190 pF1KA0 KSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQA 1900 1910 1920 1930 1940 1950 2200 2210 2220 2230 2240 2250 pF1KA0 TACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDS 1960 1970 1980 1990 2000 2010 2260 2270 2280 2290 2300 2310 pF1KA0 EKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHE 2020 2030 2040 2050 2060 2070 pF1KA0 KRHRNMHR :::::::: XP_016 KRHRNMHR >>XP_011535680 (OMIM: 604691) PREDICTED: A-kinase anchor (1415 aa) initn: 9247 init1: 9247 opt: 9247 Z-score: 7253.3 bits: 1355.3 E(85289): 0 Smith-Waterman score: 9247; 100.0% identity (100.0% similar) in 1409 aa overlap (911-2319:7-1415) 890 900 910 920 930 940 pF1KA0 WILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSS :::::::::::::::::::::::::::::: XP_011 MEITEVAEVQLCYLEAQRDAVEQMSLKLYSEQYTSS 10 20 30 950 960 970 980 990 1000 pF1KA0 SKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYK 40 50 60 70 80 90 1010 1020 1030 1040 1050 1060 pF1KA0 RYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTM 100 110 120 130 140 150 1070 1080 1090 1100 1110 1120 pF1KA0 AGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQL 160 170 180 190 200 210 1130 1140 1150 1160 1170 1180 pF1KA0 QYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQ 220 230 240 250 260 270 1190 1200 1210 1220 1230 1240 pF1KA0 AVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQ 280 290 300 310 320 330 1250 1260 1270 1280 1290 1300 pF1KA0 ELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDN 340 350 360 370 380 390 1310 1320 1330 1340 1350 1360 pF1KA0 HMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNS 400 410 420 430 440 450 1370 1380 1390 1400 1410 1420 pF1KA0 GSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESI 460 470 480 490 500 510 1430 1440 1450 1460 1470 1480 pF1KA0 KLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKL 520 530 540 550 560 570 1490 1500 1510 1520 1530 1540 pF1KA0 PMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRIS 580 590 600 610 620 630 1550 1560 1570 1580 1590 1600 pF1KA0 YKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWL 640 650 660 670 680 690 1610 1620 1630 1640 1650 1660 pF1KA0 TSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQ 700 710 720 730 740 750 1670 1680 1690 1700 1710 1720 pF1KA0 SSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRK 760 770 780 790 800 810 1730 1740 1750 1760 1770 1780 pF1KA0 RLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIA 820 830 840 850 860 870 1790 1800 1810 1820 1830 1840 pF1KA0 TDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPS 880 890 900 910 920 930 1850 1860 1870 1880 1890 1900 pF1KA0 DTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIE 940 950 960 970 980 990 1910 1920 1930 1940 1950 1960 pF1KA0 GIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHL 1000 1010 1020 1030 1040 1050 1970 1980 1990 2000 2010 2020 pF1KA0 PKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCL 1060 1070 1080 1090 1100 1110 2030 2040 2050 2060 2070 2080 pF1KA0 ALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENE 1120 1130 1140 1150 1160 1170 2090 2100 2110 2120 2130 2140 pF1KA0 VAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLD 1180 1190 1200 1210 1220 1230 2150 2160 2170 2180 2190 2200 pF1KA0 TTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSD 1240 1250 1260 1270 1280 1290 2210 2220 2230 2240 2250 2260 pF1KA0 SSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPG 1300 1310 1320 1330 1340 1350 2270 2280 2290 2300 2310 pF1KA0 ESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR 1360 1370 1380 1390 1400 1410 >>XP_016877300 (OMIM: 604691) PREDICTED: A-kinase anchor (1415 aa) initn: 9247 init1: 9247 opt: 9247 Z-score: 7253.3 bits: 1355.3 E(85289): 0 Smith-Waterman score: 9247; 100.0% identity (100.0% similar) in 1409 aa overlap (911-2319:7-1415) 890 900 910 920 930 940 pF1KA0 WILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSS :::::::::::::::::::::::::::::: XP_016 MEITEVAEVQLCYLEAQRDAVEQMSLKLYSEQYTSS 10 20 30 950 960 970 980 990 1000 pF1KA0 SKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYK 40 50 60 70 80 90 1010 1020 1030 1040 1050 1060 pF1KA0 RYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTM 100 110 120 130 140 150 1070 1080 1090 1100 1110 1120 pF1KA0 AGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQL 160 170 180 190 200 210 1130 1140 1150 1160 1170 1180 pF1KA0 QYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQ 220 230 240 250 260 270 1190 1200 1210 1220 1230 1240 pF1KA0 AVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQ 280 290 300 310 320 330 1250 1260 1270 1280 1290 1300 pF1KA0 ELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDN 340 350 360 370 380 390 1310 1320 1330 1340 1350 1360 pF1KA0 HMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNS 400 410 420 430 440 450 1370 1380 1390 1400 1410 1420 pF1KA0 GSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESI 460 470 480 490 500 510 1430 1440 1450 1460 1470 1480 pF1KA0 KLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKL 520 530 540 550 560 570 1490 1500 1510 1520 1530 1540 pF1KA0 PMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRIS 580 590 600 610 620 630 1550 1560 1570 1580 1590 1600 pF1KA0 YKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWL 640 650 660 670 680 690 1610 1620 1630 1640 1650 1660 pF1KA0 TSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQ 700 710 720 730 740 750 1670 1680 1690 1700 1710 1720 pF1KA0 SSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRK 760 770 780 790 800 810 1730 1740 1750 1760 1770 1780 pF1KA0 RLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIA 820 830 840 850 860 870 1790 1800 1810 1820 1830 1840 pF1KA0 TDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPS 880 890 900 910 920 930 1850 1860 1870 1880 1890 1900 pF1KA0 DTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIE 940 950 960 970 980 990 1910 1920 1930 1940 1950 1960 pF1KA0 GIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHL 1000 1010 1020 1030 1040 1050 1970 1980 1990 2000 2010 2020 pF1KA0 PKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCL 1060 1070 1080 1090 1100 1110 2030 2040 2050 2060 2070 2080 pF1KA0 ALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENE 1120 1130 1140 1150 1160 1170 2090 2100 2110 2120 2130 2140 pF1KA0 VAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLD 1180 1190 1200 1210 1220 1230 2150 2160 2170 2180 2190 2200 pF1KA0 TTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSD 1240 1250 1260 1270 1280 1290 2210 2220 2230 2240 2250 2260 pF1KA0 SSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPG 1300 1310 1320 1330 1340 1350 2270 2280 2290 2300 2310 pF1KA0 ESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR 1360 1370 1380 1390 1400 1410 >>XP_011535681 (OMIM: 604691) PREDICTED: A-kinase anchor (1392 aa) initn: 9137 init1: 9137 opt: 9137 Z-score: 7167.2 bits: 1339.4 E(85289): 0 Smith-Waterman score: 9137; 100.0% identity (100.0% similar) in 1392 aa overlap (928-2319:1-1392) 900 910 920 930 940 950 pF1KA0 VSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVG :::::::::::::::::::::::::::::: XP_011 MSLKLYSEQYTSSSKRKEEFADMSKVHSVG 10 20 30 960 970 980 990 1000 1010 pF1KA0 SNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELL 40 50 60 70 80 90 1020 1030 1040 1050 1060 1070 pF1KA0 SKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESG 100 110 120 130 140 150 1080 1090 1100 1110 1120 1130 pF1KA0 SLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGV 160 170 180 190 200 210 1140 1150 1160 1170 1180 1190 pF1KA0 ASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESE 220 230 240 250 260 270 1200 1210 1220 1230 1240 1250 pF1KA0 TLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNE 280 290 300 310 320 330 1260 1270 1280 1290 1300 1310 pF1KA0 DPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQP 340 350 360 370 380 390 1320 1330 1340 1350 1360 1370 pF1KA0 NVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTN 400 410 420 430 440 450 1380 1390 1400 1410 1420 1430 pF1KA0 SEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVN 460 470 480 490 500 510 1440 1450 1460 1470 1480 1490 pF1KA0 GKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDP 520 530 540 550 560 570 1500 1510 1520 1530 1540 1550 pF1KA0 LLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAK 580 590 600 610 620 630 1560 1570 1580 1590 1600 1610 pF1KA0 QLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGD 640 650 660 670 680 690 1620 1630 1640 1650 1660 1670 pF1KA0 ISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIA 700 710 720 730 740 750 1680 1690 1700 1710 1720 1730 pF1KA0 SSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMI 760 770 780 790 800 810 1740 1750 1760 1770 1780 1790 pF1KA0 VNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDY 820 830 840 850 860 870 1800 1810 1820 1830 1840 1850 pF1KA0 IKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVS 880 890 900 910 920 930 1860 1870 1880 1890 1900 1910 pF1KA0 ENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVS 940 950 960 970 980 990 1920 1930 1940 1950 1960 1970 pF1KA0 ENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTAS 1000 1010 1020 1030 1040 1050 1980 1990 2000 2010 2020 2030 pF1KA0 TPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNIS 1060 1070 1080 1090 1100 1110 2040 2050 2060 2070 2080 2090 pF1KA0 CCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEH 1120 1130 1140 1150 1160 1170 2100 2110 2120 2130 2140 2150 pF1KA0 SHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFE 1180 1190 1200 1210 1220 1230 2160 2170 2180 2190 2200 2210 pF1KA0 ACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPS 1240 1250 1260 1270 1280 1290 2220 2230 2240 2250 2260 2270 pF1KA0 SQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKV 1300 1310 1320 1330 1340 1350 2280 2290 2300 2310 pF1KA0 QDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR :::::::::::::::::::::::::::::::::::::::::: XP_011 QDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR 1360 1370 1380 1390 >>XP_011535685 (OMIM: 604691) PREDICTED: A-kinase anchor (1314 aa) initn: 8622 init1: 8622 opt: 8622 Z-score: 6763.9 bits: 1264.7 E(85289): 0 Smith-Waterman score: 8622; 100.0% identity (100.0% similar) in 1314 aa overlap (1006-2319:1-1314) 980 990 1000 1010 1020 1030 pF1KA0 IDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLL :::::::::::::::::::::::::::::: XP_011 MSIRHLKKTELLSKVEALKKGGVLLPNDLL 10 20 30 1040 1050 1060 1070 1080 1090 pF1KA0 EKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLR 40 50 60 70 80 90 1100 1110 1120 1130 1140 1150 pF1KA0 DTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCN 100 110 120 130 140 150 1160 1170 1180 1190 1200 1210 pF1KA0 LNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSED 160 170 180 190 200 210 1220 1230 1240 1250 1260 1270 pF1KA0 ALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYAS 220 230 240 250 260 270 1280 1290 1300 1310 1320 1330 pF1KA0 NITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKS 280 290 300 310 320 330 1340 1350 1360 1370 1380 1390 pF1KA0 LPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLET 340 350 360 370 380 390 1400 1410 1420 1430 1440 1450 pF1KA0 EHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLG 400 410 420 430 440 450 1460 1470 1480 1490 1500 1510 pF1KA0 EELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQT 460 470 480 490 500 510 1520 1530 1540 1550 1560 1570 pF1KA0 TELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGG 520 530 540 550 560 570 1580 1590 1600 1610 1620 1630 pF1KA0 DLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDL 580 590 600 610 620 630 1640 1650 1660 1670 1680 1690 pF1KA0 LNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSD 640 650 660 670 680 690 1700 1710 1720 1730 1740 1750 pF1KA0 ELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDL 700 710 720 730 740 750 1760 1770 1780 1790 1800 1810 pF1KA0 LSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRD 760 770 780 790 800 810 1820 1830 1840 1850 1860 1870 pF1KA0 KKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTK 820 830 840 850 860 870 1880 1890 1900 1910 1920 1930 pF1KA0 RENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKC 880 890 900 910 920 930 1940 1950 1960 1970 1980 1990 pF1KA0 KALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNN 940 950 960 970 980 990 2000 2010 2020 2030 2040 2050 pF1KA0 RQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCS 1000 1010 1020 1030 1040 1050 2060 2070 2080 2090 2100 2110 pF1KA0 VHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSL 1060 1070 1080 1090 1100 1110 2120 2130 2140 2150 2160 2170 pF1KA0 SSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAP 1120 1130 1140 1150 1160 1170 2180 2190 2200 2210 2220 2230 pF1KA0 PNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTS 1180 1190 1200 1210 1220 1230 2240 2250 2260 2270 2280 2290 pF1KA0 SGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHP 1240 1250 1260 1270 1280 1290 2300 2310 pF1KA0 SPKTLTCEENLLNLHEKRHRNMHR :::::::::::::::::::::::: XP_011 SPKTLTCEENLLNLHEKRHRNMHR 1300 1310 >>NP_001306029 (OMIM: 616889) centrosomal protein of 68 (757 aa) initn: 253 init1: 164 opt: 257 Z-score: 210.2 bits: 51.2 E(85289): 5.7e-05 Smith-Waterman score: 275; 23.0% identity (48.6% similar) in 718 aa overlap (233-897:95-743) 210 220 230 240 250 pF1KA0 DSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGL-------GDMTSSQVKTKPFDS :: :::: ::. : . . NP_001 TCWIGTDPGGPSRAHQPQASDANREPVAERSEPALSGLPPATMGSGDLLLSGESQVEKTK 70 80 90 100 110 120 260 270 280 290 300 310 pF1KA0 WSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAV : :: :::. :.. . .: .: :: :: . . .: . NP_001 LSSSE---EFPQ------TLSLPRTTTICSGHDADTE---------DDPSLADLPQALDL 130 140 150 160 320 330 340 350 360 370 pF1KA0 EEQP---GLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPK-- .:: ::. . .: . .:::::: ... :..:: ...: : : :. NP_001 SQQPHSSGLSCLSQWKSVLSPGSAAQPSSCSISASSTGSS---LQGHQ----ERAEPRGG 170 180 190 200 210 380 390 400 410 420 pF1KA0 RTIRDCFNYNEDSPTQPT----LPKRGLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTP . . . : .:. : : . . .:.. .. :.:.. . : NP_001 SLAKVSSSLEPVVPQEPSSVVGLGPRPQWSPQPVFSGGDASGLGRRRLSFQAEYWACVLP 220 230 240 250 260 270 430 440 450 460 470 pF1KA0 SLVDP-PDR--------SKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKE . . : ::: .. .:. .:: :. : : .:.. : NP_001 DSLPPSPDRHSPLWNPNKEYEDLLDYTYPLRPGPQ------LPK----HLDSRVPADPVL 280 290 300 310 320 480 490 500 510 520 530 pF1KA0 ISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKS--SAVPN--GE .:.. . . : ::.: ..: . :: .. :: . . :. : ::. : NP_001 QDSGVDLDSFSVSPASTLKSPTNVSPNCPPAEATALPF-SGPREPSLKQWPSRVPQKQGG 330 340 350 360 370 380 540 550 560 570 580 590 pF1KA0 LSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMS .. .: .. ::: . :. . . ... .: ... ..:: .. . NP_001 MGLAS------WSQLASTPRAPGSRDARWERREP--ALRGAKDRLTIGKHLDMGSPQLRT 390 400 410 420 430 440 600 610 620 630 640 pF1KA0 -----PVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLE : : ..: . .: :. . . : ..:::::::..: :. :. : NP_001 RDRGWPSPRPEREKRTSQSARRPTCTESRWKSEEEVESDDEYLALPARLTQVSSLVSYLG 450 460 470 480 490 500 650 660 670 680 690 700 pF1KA0 NLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSL ... :. : :. :.. . :.: ::. .. :::::. NP_001 SISTLVTL-PTGD-IKGQSPLEVS----DSDGPASF-------------PSSSSQSQLPP 510 520 530 540 710 720 730 740 750 760 pF1KA0 GESIESGPLSDILSDEESSMP--LAGMKKYADEKSERASSSEKNESHSA----TKSALIQ : ..... .: :.. : : .. . : .: . .: . . :. :. .: NP_001 GAALQGS------GDPEGQNPCFLRSFVRAHDSAGEGSLGSSQALGVSSGLLKTRPSLPA 550 560 570 580 590 770 780 790 800 pF1KA0 KLMQ------DIQHQ-------DNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPK .: . :.. : .. :.. . .. : .:.:.: :: .. ..:.. : . NP_001 RLDRWPFSDPDVEGQLPRKGGEQGKESLVQCVKTFCCQLEELICWLYNVADVTDHGTAAR 600 610 620 630 640 650 810 820 830 840 850 860 pF1KA0 AEMDDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLRMIASQWK ... .:: :. . .:: ..: : .: :.: ..:. ::. . . :.:.: ::.: NP_001 SNLTSLKSSLQLYRQFKKDIDEHQSLTESVLQKGEILLQCLLENTPVLEDVLGRIAKQSG 660 670 680 690 700 710 870 880 890 900 910 920 pF1KA0 ELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMS ::. . : .. :: .:: . . : : NP_001 ELESHADRLYDSILASLDMLAGCTLIPDKKPMAAMEHPCEGV 720 730 740 750 >>NP_055962 (OMIM: 616889) centrosomal protein of 68 kDa (757 aa) initn: 253 init1: 164 opt: 257 Z-score: 210.2 bits: 51.2 E(85289): 5.7e-05 Smith-Waterman score: 275; 23.0% identity (48.6% similar) in 718 aa overlap (233-897:95-743) 210 220 230 240 250 pF1KA0 DSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGL-------GDMTSSQVKTKPFDS :: :::: ::. : . . NP_055 TCWIGTDPGGPSRAHQPQASDANREPVAERSEPALSGLPPATMGSGDLLLSGESQVEKTK 70 80 90 100 110 120 260 270 280 290 300 310 pF1KA0 WSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAV : :: :::. :.. . .: .: :: :: . . .: . NP_055 LSSSE---EFPQ------TLSLPRTTTICSGHDADTE---------DDPSLADLPQALDL 130 140 150 160 320 330 340 350 360 370 pF1KA0 EEQP---GLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPK-- .:: ::. . .: . .:::::: ... :..:: ...: : : :. NP_055 SQQPHSSGLSCLSQWKSVLSPGSAAQPSSCSISASSTGSS---LQGHQ----ERAEPRGG 170 180 190 200 210 380 390 400 410 420 pF1KA0 RTIRDCFNYNEDSPTQPT----LPKRGLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTP . . . : .:. : : . . .:.. .. :.:.. . : NP_055 SLAKVSSSLEPVVPQEPSSVVGLGPRPQWSPQPVFSGGDASGLGRRRLSFQAEYWACVLP 220 230 240 250 260 270 430 440 450 460 470 pF1KA0 SLVDP-PDR--------SKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKE . . : ::: .. .:. .:: :. : : .:.. : NP_055 DSLPPSPDRHSPLWNPNKEYEDLLDYTYPLRPGPQ------LPK----HLDSRVPADPVL 280 290 300 310 320 480 490 500 510 520 530 pF1KA0 ISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKS--SAVPN--GE .:.. . . : ::.: ..: . :: .. :: . . :. : ::. : NP_055 QDSGVDLDSFSVSPASTLKSPTNVSPNCPPAEATALPF-SGPREPSLKQWPSRVPQKQGG 330 340 350 360 370 380 540 550 560 570 580 590 pF1KA0 LSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMS .. .: .. ::: . :. . . ... .: ... ..:: .. . NP_055 MGLAS------WSQLASTPRAPGSRDARWERREP--ALRGAKDRLTIGKHLDMGSPQLRT 390 400 410 420 430 440 600 610 620 630 640 pF1KA0 -----PVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLE : : ..: . .: :. . . : ..:::::::..: :. :. : NP_055 RDRGWPSPRPEREKRTSQSARRPTCTESRWKSEEEVESDDEYLALPARLTQVSSLVSYLG 450 460 470 480 490 500 650 660 670 680 690 700 pF1KA0 NLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSL ... :. : :. :.. . :.: ::. .. :::::. NP_055 SISTLVTL-PTGD-IKGQSPLEVS----DSDGPASF-------------PSSSSQSQLPP 510 520 530 540 710 720 730 740 750 760 pF1KA0 GESIESGPLSDILSDEESSMP--LAGMKKYADEKSERASSSEKNESHSA----TKSALIQ : ..... .: :.. : : .. . : .: . .: . . :. :. .: NP_055 GAALQGS------GDPEGQNPCFLRSFVRAHDSAGEGSLGSSQALGVSSGLLKTRPSLPA 550 560 570 580 590 770 780 790 800 pF1KA0 KLMQ------DIQHQ-------DNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPK .: . :.. : .. :.. . .. : .:.:.: :: .. ..:.. : . NP_055 RLDRWPFSDPDVEGQLPRKGGEQGKESLVQCVKTFCCQLEELICWLYNVADVTDHGTAAR 600 610 620 630 640 650 810 820 830 840 850 860 pF1KA0 AEMDDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLRMIASQWK ... .:: :. . .:: ..: : .: :.: ..:. ::. . . :.:.: ::.: NP_055 SNLTSLKSSLQLYRQFKKDIDEHQSLTESVLQKGEILLQCLLENTPVLEDVLGRIAKQSG 660 670 680 690 700 710 870 880 890 900 910 920 pF1KA0 ELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMS ::. . : .. :: .:: . . : : NP_055 ELESHADRLYDSILASLDMLAGCTLIPDKKPMAAMEHPCEGV 720 730 740 750 2319 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:32:52 2016 done: Wed Nov 2 18:32:55 2016 Total Scan time: 20.450 Total Display time: 1.070 Function used was FASTA [36.3.4 Apr, 2011]