FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0318, 1052 aa 1>>>pF1KA0318 1052 - 1052 aa - 1052 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1374+/-0.000406; mu= -0.1926+/- 0.025 mean_var=268.7537+/-55.832, 0's: 0 Z-trim(119.7): 120 B-trim: 282 in 1/58 Lambda= 0.078234 statistics sampled from 33926 (34055) to 33926 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.399), width: 16 Scan time: 17.040 The best scores are: opt bits E(85289) NP_056162 (OMIM: 611602) RIMS-binding protein 2 [H (1052) 7038 808.7 0 XP_016874599 (OMIM: 611602) PREDICTED: RIMS-bindin (1069) 6843 786.7 0 XP_016874600 (OMIM: 611602) PREDICTED: RIMS-bindin (1069) 6794 781.1 0 XP_016874597 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 6794 781.1 0 XP_016874598 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 6794 781.1 0 XP_016874596 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 6794 781.1 0 XP_016874595 (OMIM: 611602) PREDICTED: RIMS-bindin (1190) 6794 781.2 0 XP_011536407 (OMIM: 611602) PREDICTED: RIMS-bindin (1244) 6794 781.2 0 XP_011536406 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 5059 585.4 7.5e-166 XP_011536404 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 5059 585.4 7.5e-166 XP_016874594 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 5059 585.4 7.5e-166 XP_011536405 (OMIM: 611602) PREDICTED: RIMS-bindin (1429) 5059 585.4 7.7e-166 XP_016874601 (OMIM: 611602) PREDICTED: RIMS-bindin ( 753) 4674 541.7 5.6e-153 XP_011536410 (OMIM: 611602) PREDICTED: RIMS-bindin ( 874) 4674 541.8 6.3e-153 XP_011536409 (OMIM: 611602) PREDICTED: RIMS-bindin ( 875) 4674 541.8 6.3e-153 XP_011536408 (OMIM: 611602) PREDICTED: RIMS-bindin (1191) 4674 541.9 8.1e-153 XP_016880821 (OMIM: 610764) PREDICTED: peripheral- (1517) 1335 165.1 2.7e-39 XP_016880820 (OMIM: 610764) PREDICTED: peripheral- (1568) 1335 165.1 2.8e-39 XP_016880819 (OMIM: 610764) PREDICTED: peripheral- (1577) 1335 165.1 2.8e-39 XP_016880818 (OMIM: 610764) PREDICTED: peripheral- (1627) 1335 165.1 2.9e-39 XP_016880823 (OMIM: 610764) PREDICTED: peripheral- (1240) 820 106.9 7.4e-22 XP_016880822 (OMIM: 610764) PREDICTED: peripheral- (1291) 820 106.9 7.6e-22 XP_011523774 (OMIM: 610764) PREDICTED: peripheral- (1411) 433 63.3 1.2e-08 XP_011523773 (OMIM: 610764) PREDICTED: peripheral- (1428) 433 63.3 1.2e-08 XP_006722241 (OMIM: 610764) PREDICTED: peripheral- (1467) 433 63.3 1.2e-08 XP_006722240 (OMIM: 610764) PREDICTED: peripheral- (1467) 433 63.3 1.2e-08 XP_006722239 (OMIM: 610764) PREDICTED: peripheral- (1630) 433 63.3 1.3e-08 NP_077729 (OMIM: 610764) peripheral-type benzodiaz (1797) 433 63.3 1.4e-08 XP_016880817 (OMIM: 610764) PREDICTED: peripheral- (1804) 433 63.3 1.4e-08 XP_006722238 (OMIM: 610764) PREDICTED: peripheral- (1847) 433 63.3 1.4e-08 NP_001248764 (OMIM: 610764) peripheral-type benzod (1848) 433 63.3 1.4e-08 NP_004749 (OMIM: 610764) peripheral-type benzodiaz (1857) 433 63.3 1.4e-08 XP_016880816 (OMIM: 610764) PREDICTED: peripheral- (1868) 433 63.3 1.4e-08 XP_016880815 (OMIM: 610764) PREDICTED: peripheral- (1879) 433 63.3 1.4e-08 XP_005257864 (OMIM: 610764) PREDICTED: peripheral- (1898) 433 63.3 1.5e-08 XP_006722237 (OMIM: 610764) PREDICTED: peripheral- (1900) 433 63.3 1.5e-08 XP_006722236 (OMIM: 610764) PREDICTED: peripheral- (1907) 433 63.3 1.5e-08 NP_056487 (OMIM: 612699) RIMS-binding protein 3A [ (1639) 355 54.5 5.8e-06 NP_001122105 (OMIM: 612701) RIMS-binding protein 3 (1639) 354 54.4 6.3e-06 NP_001122107 (OMIM: 612700) RIMS-binding protein 3 (1639) 354 54.4 6.3e-06 >>NP_056162 (OMIM: 611602) RIMS-binding protein 2 [Homo (1052 aa) initn: 7344 init1: 7038 opt: 7038 Z-score: 4307.4 bits: 808.7 E(85289): 0 Smith-Waterman score: 7038; 99.9% identity (99.9% similar) in 1052 aa overlap (1-1052:1-1052) 10 20 30 40 50 60 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKSKVRELEEKCRTQSEQFNLLSRDLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKSKVRELEEKCRTQSEQFNLLSRDLEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 FRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 FDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 STLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 STLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 VIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 PLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 GTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 TSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 TDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 ARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVAL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 YDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDD 970 980 990 1000 1010 1020 1030 1040 1050 pF1KA0 VEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP :::::::::::::::::::::::::::::: : NP_056 VEVYLSDAPSHYSQDTPMRSKAKRKKSVHFTP 1030 1040 1050 >>XP_016874599 (OMIM: 611602) PREDICTED: RIMS-binding pr (1069 aa) initn: 7335 init1: 6833 opt: 6843 Z-score: 4188.3 bits: 786.7 E(85289): 0 Smith-Waterman score: 6994; 98.3% identity (98.3% similar) in 1069 aa overlap (1-1052:1-1069) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFTP 1030 1040 1050 1060 >>XP_016874600 (OMIM: 611602) PREDICTED: RIMS-binding pr (1069 aa) initn: 6784 init1: 6784 opt: 6794 Z-score: 4158.4 bits: 781.1 E(85289): 0 Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::: XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRGFHDSSTS 1030 1040 1050 1060 >>XP_016874597 (OMIM: 611602) PREDICTED: RIMS-binding pr (1123 aa) initn: 6784 init1: 6784 opt: 6794 Z-score: 4158.1 bits: 781.1 E(85289): 0 Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::: XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAPSPTVHL 1030 1040 1050 1060 1070 1080 XP_016 HSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK 1090 1100 1110 1120 >>XP_016874598 (OMIM: 611602) PREDICTED: RIMS-binding pr (1123 aa) initn: 6784 init1: 6784 opt: 6794 Z-score: 4158.1 bits: 781.1 E(85289): 0 Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::: XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAPSPTVHL 1030 1040 1050 1060 1070 1080 XP_016 HSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK 1090 1100 1110 1120 >>XP_016874596 (OMIM: 611602) PREDICTED: RIMS-binding pr (1123 aa) initn: 6784 init1: 6784 opt: 6794 Z-score: 4158.1 bits: 781.1 E(85289): 0 Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::: XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAPSPTVHL 1030 1040 1050 1060 1070 1080 XP_016 HSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK 1090 1100 1110 1120 >>XP_016874595 (OMIM: 611602) PREDICTED: RIMS-binding pr (1190 aa) initn: 6784 init1: 6784 opt: 6794 Z-score: 4157.8 bits: 781.2 E(85289): 0 Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:122-1182) 10 20 30 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEID :::::::::::::::::::::::::::::: XP_016 TLVTRERDLAVKEKHQLQAKLENLEQVLKHMREAAERRQQLQLEHDQALAVLSAKQQEID 100 110 120 130 140 150 40 50 60 70 pF1KA0 LLQK-----------------SKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG :::: ::::::::::::::::::::::::::::::::::::::: XP_016 LLQKAQVEAKKEHEGAVRLLESKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG 160 170 180 190 200 210 80 90 100 110 120 130 pF1KA0 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA 220 230 240 250 260 270 140 150 160 170 180 190 pF1KA0 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP 280 290 300 310 320 330 200 210 220 230 240 250 pF1KA0 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN 340 350 360 370 380 390 260 270 280 290 300 310 pF1KA0 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV 400 410 420 430 440 450 320 330 340 350 360 370 pF1KA0 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS 460 470 480 490 500 510 380 390 400 410 420 430 pF1KA0 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK 520 530 540 550 560 570 440 450 460 470 480 490 pF1KA0 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV 580 590 600 610 620 630 500 510 520 530 540 550 pF1KA0 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR 640 650 660 670 680 690 560 570 580 590 600 610 pF1KA0 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE 700 710 720 730 740 750 620 630 640 650 660 670 pF1KA0 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA 760 770 780 790 800 810 680 690 700 710 720 730 pF1KA0 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK 820 830 840 850 860 870 740 750 760 770 780 790 pF1KA0 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA 880 890 900 910 920 930 800 810 820 830 840 850 pF1KA0 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF 940 950 960 970 980 990 860 870 880 890 900 910 pF1KA0 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE 1000 1010 1020 1030 1040 1050 920 930 940 950 960 970 pF1KA0 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD 1060 1070 1080 1090 1100 1110 980 990 1000 1010 1020 1030 pF1KA0 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS 1120 1130 1140 1150 1160 1170 1040 1050 pF1KA0 QDTPMRSKAKRKKSVHFIP ::::::::::: XP_016 QDTPMRSKAKRGFHDSSTS 1180 1190 >>XP_011536407 (OMIM: 611602) PREDICTED: RIMS-binding pr (1244 aa) initn: 6784 init1: 6784 opt: 6794 Z-score: 4157.5 bits: 781.2 E(85289): 0 Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:122-1182) 10 20 30 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEID :::::::::::::::::::::::::::::: XP_011 TLVTRERDLAVKEKHQLQAKLENLEQVLKHMREAAERRQQLQLEHDQALAVLSAKQQEID 100 110 120 130 140 150 40 50 60 70 pF1KA0 LLQK-----------------SKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG :::: ::::::::::::::::::::::::::::::::::::::: XP_011 LLQKAQVEAKKEHEGAVRLLESKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG 160 170 180 190 200 210 80 90 100 110 120 130 pF1KA0 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA 220 230 240 250 260 270 140 150 160 170 180 190 pF1KA0 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP 280 290 300 310 320 330 200 210 220 230 240 250 pF1KA0 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN 340 350 360 370 380 390 260 270 280 290 300 310 pF1KA0 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV 400 410 420 430 440 450 320 330 340 350 360 370 pF1KA0 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS 460 470 480 490 500 510 380 390 400 410 420 430 pF1KA0 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK 520 530 540 550 560 570 440 450 460 470 480 490 pF1KA0 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV 580 590 600 610 620 630 500 510 520 530 540 550 pF1KA0 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR 640 650 660 670 680 690 560 570 580 590 600 610 pF1KA0 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE 700 710 720 730 740 750 620 630 640 650 660 670 pF1KA0 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA 760 770 780 790 800 810 680 690 700 710 720 730 pF1KA0 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK 820 830 840 850 860 870 740 750 760 770 780 790 pF1KA0 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA 880 890 900 910 920 930 800 810 820 830 840 850 pF1KA0 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF 940 950 960 970 980 990 860 870 880 890 900 910 pF1KA0 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE 1000 1010 1020 1030 1040 1050 920 930 940 950 960 970 pF1KA0 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD 1060 1070 1080 1090 1100 1110 980 990 1000 1010 1020 1030 pF1KA0 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS 1120 1130 1140 1150 1160 1170 1040 1050 pF1KA0 QDTPMRSKAKRKKSVHFIP ::::::::::: XP_011 QDTPMRSKAKRVPPEGSGTARRAPSPTVHLHSGSPTSSMGSGSPGRGREMSSKKKKGLLS 1180 1190 1200 1210 1220 1230 >>XP_011536406 (OMIM: 611602) PREDICTED: RIMS-binding pr (1362 aa) initn: 6770 init1: 5037 opt: 5059 Z-score: 3098.6 bits: 585.4 E(85289): 7.5e-166 Smith-Waterman score: 5210; 94.5% identity (95.8% similar) in 841 aa overlap (1-823:1-837) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_011 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALK-ILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPS :::::::::::::::::::::::: . .: : .. . ::. :.:.: ..: XP_011 LYSEMQLEDGGRRRPSGTSHNALKDCTDHRTSEGTFWEQPE-FPH---QPHRKRLFSIPE 790 800 810 820 830 830 840 850 860 870 880 pF1KA0 IDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQI . XP_011 VAEEDGECCGLLHKQGAGPSPRARTGLAREPRPGRPYRGDEAPRGSWFPVKHRGSGAVPH 840 850 860 870 880 890 >-- initn: 1777 init1: 1747 opt: 1747 Z-score: 1078.3 bits: 211.6 E(85289): 2.5e-53 Smith-Waterman score: 1747; 100.0% identity (100.0% similar) in 257 aa overlap (788-1044:1044-1300) 760 770 780 790 800 810 pF1KA0 EEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRP :::::::::::::::::::::::::::::: XP_011 GVWKKSITMPDSRAAAPHAKPPPRVAQGPLILGNPASAGRVDHMGRRFPRGSAGPQRSRP 1020 1030 1040 1050 1060 1070 820 830 840 850 860 870 pF1KA0 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF 1080 1090 1100 1110 1120 1130 880 890 900 910 920 930 pF1KA0 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV 1140 1150 1160 1170 1180 1190 940 950 960 970 980 990 pF1KA0 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF 1200 1210 1220 1230 1240 1250 1000 1010 1020 1030 1040 1050 pF1KA0 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAP 1260 1270 1280 1290 1300 1310 XP_011 SPTVHLHSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK 1320 1330 1340 1350 1360 >>XP_011536404 (OMIM: 611602) PREDICTED: RIMS-binding pr (1362 aa) initn: 6770 init1: 5037 opt: 5059 Z-score: 3098.6 bits: 585.4 E(85289): 7.5e-166 Smith-Waterman score: 5210; 94.5% identity (95.8% similar) in 841 aa overlap (1-823:1-837) 10 20 30 40 pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK :::::::::::::::::::::::::::::::::: ::::::::: XP_011 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 LYSEMQLEDGGRRRPSGTSHNALK-ILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPS :::::::::::::::::::::::: . .: : .. . ::. :.:.: ..: XP_011 LYSEMQLEDGGRRRPSGTSHNALKDCTDHRTSEGTFWEQPE-FPH---QPHRKRLFSIPE 790 800 810 820 830 830 840 850 860 870 880 pF1KA0 IDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQI . XP_011 VAEEDGECCGLLHKQGAGPSPRARTGLAREPRPGRPYRGDEAPRGSWFPVKHRGSGAVPH 840 850 860 870 880 890 >-- initn: 1777 init1: 1747 opt: 1747 Z-score: 1078.3 bits: 211.6 E(85289): 2.5e-53 Smith-Waterman score: 1747; 100.0% identity (100.0% similar) in 257 aa overlap (788-1044:1044-1300) 760 770 780 790 800 810 pF1KA0 EEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRP :::::::::::::::::::::::::::::: XP_011 GVWKKSITMPDSRAAAPHAKPPPRVAQGPLILGNPASAGRVDHMGRRFPRGSAGPQRSRP 1020 1030 1040 1050 1060 1070 820 830 840 850 860 870 pF1KA0 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF 1080 1090 1100 1110 1120 1130 880 890 900 910 920 930 pF1KA0 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV 1140 1150 1160 1170 1180 1190 940 950 960 970 980 990 pF1KA0 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF 1200 1210 1220 1230 1240 1250 1000 1010 1020 1030 1040 1050 pF1KA0 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAP 1260 1270 1280 1290 1300 1310 XP_011 SPTVHLHSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK 1320 1330 1340 1350 1360 1052 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:38:08 2016 done: Fri Nov 4 00:38:11 2016 Total Scan time: 17.040 Total Display time: 0.390 Function used was FASTA [36.3.4 Apr, 2011]