FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0321, 2539 aa 1>>>pF1KA0321 2539 - 2539 aa - 2539 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4710+/-0.000997; mu= 16.8299+/- 0.060 mean_var=137.1233+/-27.268, 0's: 0 Z-trim(108.6): 52 B-trim: 0 in 0/53 Lambda= 0.109526 statistics sampled from 10254 (10304) to 10254 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.317), width: 16 Scan time: 7.740 The best scores are: opt bits E(32554) CCDS9788.1 ZFYVE26 gene_id:23503|Hs108|chr14 (2539) 17027 2703.7 0 >>CCDS9788.1 ZFYVE26 gene_id:23503|Hs108|chr14 (2539 aa) initn: 17027 init1: 17027 opt: 17027 Z-score: 14535.2 bits: 2703.7 E(32554): 0 Smith-Waterman score: 17027; 99.9% identity (100.0% similar) in 2539 aa overlap (1-2539:1-2539) 10 20 30 40 50 60 pF1KA0 MNHPFGKEEAASQKQLFGFFCECLRRGEWELAQACVPQLQEGQGDIPKRVEDILQALVVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MNHPFGKEEAASQKQLFGFFCECLRRGEWELAQACVPQLQEGQGDIPKRVEDILQALVVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PNLLRCGQDINPQRVAWVWLLVLEKWLAREKKLLPVVFRRKLEFLLLSEDLQGDIPENIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 PNLLRCGQDINPQRVAWVWLLVLEKWLAREKKLLPVVFRRKLEFLLLSEDLQGDIPENIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EELYETLTQGAVGHVPDGNPRRESWTPRLSSEAVSVLWDLLRQSPQPAQALLELLLEEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 EELYETLTQGAVGHVPDGNPRRESWTPRLSSEAVSVLWDLLRQSPQPAQALLELLLEEDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 GTGLCHWPLQNALVDLIRKALRALQGPDSVPPGVVDAIYGALRTLRCPAEPLGVELHLLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GTGLCHWPLQNALVDLIRKALRALQGPDSVPPGVVDAIYGALRTLRCPAEPLGVELHLLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EELLEACRTEGSPLREERLLSCLLHKASRGLLSLYGHTYAEKVTEKPPRATASGKVSPDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 EELLEACRTEGSPLREERLLSCLLHKASRGLLSLYGHTYAEKVTEKPPRATASGKVSPDH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 LDPERAMLALFSNPNPAEAWKVAYFYCLSNNKHFLEQILVTALTLLKEEDFPNLGCLLDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 LDPERAMLALFSNPNPAEAWKVAYFYCLSNNKHFLEQILVTALTLLKEEDFPNLGCLLDR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EFRPLSCLLVLLGWTHCQSLESAKRLLQTLHRTQGPGCDELLRDACDGLWAHLEVLEWCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 EFRPLSCLLVLLGWTHCQSLESAKRLLQTLHRTQGPGCDELLRDACDGLWAHLEVLEWCI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 QQSSNPIPKRDLLYHLHGGDSHSVLYTLHHLTNLPALREEDVLKLLQKVPAKDPQQEPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 QQSSNPIPKRDLLYHLHGGDSHSVLYTLHHLTNLPALREEDVLKLLQKVPAKDPQQEPDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VDAPVPEHLSQCQNLTLYQGFCAMKYAIYALCVNSHQHSQCQDCKDSLSEDLASATEPAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 VDAPVPEHLSQCQNLTLYQGFCAMKYAIYALCVNSHQHSQCQDCKDSLSEDLASATEPAN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 DSLSSPGAANLFSTYPARCQQYLCSIPDSLCLELLENIFSLLLITSADLHPEPHLPEDYA ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: CCDS97 DSLSSPGAANLFSTYLARCQQYLCSIPDSLCLELLENIFSLLLITSADLHPEPHLPEDYA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EDDDIEGKSPSGLRSPSESPQHIAHPERKSERGSLGVPKTLAYTMPSHVKAEPKDSYPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 EDDDIEGKSPSGLRSPSESPQHIAHPERKSERGSLGVPKTLAYTMPSHVKAEPKDSYPGP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 HRHSFLDLKHFTSGISGFLADEFAIGAFLRLLQEQLDEISSRSPPEKPKQESQSCSGSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 HRHSFLDLKHFTSGISGFLADEFAIGAFLRLLQEQLDEISSRSPPEKPKQESQSCSGSRD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 GLQSRLHRLSKVVSEAQWRHKVVTSNHRSEEQPSRRYQPATRHPSLRRGRRTRRSQADGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GLQSRLHRLSKVVSEAQWRHKVVTSNHRSEEQPSRRYQPATRHPSLRRGRRTRRSQADGR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DRGSNPSLESTSSELSTSTSEGSLSAMSGRNELHSRLHPHPQSSLIPMMFSPPESLLASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 DRGSNPSLESTSSELSTSTSEGSLSAMSGRNELHSRLHPHPQSSLIPMMFSPPESLLASC 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ILRGNFAEAHQVLFTFNLKSSPSSGELMFMERYQEVIQELAQVEHKIENQNSDAGSSTIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ILRGNFAEAHQVLFTFNLKSSPSSGELMFMERYQEVIQELAQVEHKIENQNSDAGSSTIR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RTGSGRSTLQAIGSAAAAGMVFYSISDVTDKLLNTSGDPIPMLQEDFWISTALVEPTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 RTGSGRSTLQAIGSAAAAGMVFYSISDVTDKLLNTSGDPIPMLQEDFWISTALVEPTAPL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 REVLEDLSPPAMAAFDLACSQCQLWKTCKQLLETAERRLNSSLERRGRRIDHVLLNADGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 REVLEDLSPPAMAAFDLACSQCQLWKTCKQLLETAERRLNSSLERRGRRIDHVLLNADGI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RGFPVVLQQISKSLNYLLMTASQTKSESVEEKGGGPPRCSITELLQMCWPSLSEDCVASH :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS97 RGFPVVLQQISKSLNYLLMSASQTKSESVEEKGGGPPRCSITELLQMCWPSLSEDCVASH 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 TTLSQQLDQVLQSLREALELPEPRTPPLSSLVEQAAQKAPEAEAHPVQIQTQLLQKNLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 TTLSQQLDQVLQSLREALELPEPRTPPLSSLVEQAAQKAPEAEAHPVQIQTQLLQKNLGK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 QTPSGSRQMDYLGTFFSYCSTLAAVLLQSLSSEPDHVEVKVGNPFVLLQQSSSQLVSHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 QTPSGSRQMDYLGTFFSYCSTLAAVLLQSLSSEPDHVEVKVGNPFVLLQQSSSQLVSHLL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 FERQVPPERLAALLAQENLSLSVPQVIVSCCCEPLALCSSRQSQQTSSLLTRLGTLAQLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 FERQVPPERLAALLAQENLSLSVPQVIVSCCCEPLALCSSRQSQQTSSLLTRLGTLAQLH 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 ASHCLDDLPLSTPSSPRTTENPTLERKPYSSPRDSSLPALTSSALAFLKSRSKLLATVAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ASHCLDDLPLSTPSSPRTTENPTLERKPYSSPRDSSLPALTSSALAFLKSRSKLLATVAC 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 LGASPRLKVSKPSLSWKELRGRREVPLAAEQVARECERLLEQFPLFEAFLLAAWEPLRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 LGASPRLKVSKPSLSWKELRGRREVPLAAEQVARECERLLEQFPLFEAFLLAAWEPLRGS 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 LQQGQSLAVNLCGWASLSTVLLGLHSPIALDVLSEAFEESLVARDWSRALQLTEVYGRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 LQQGQSLAVNLCGWASLSTVLLGLHSPIALDVLSEAFEESLVARDWSRALQLTEVYGRDV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 DDLSSIKDAVLSCAVACDKEGWQYLFPVKDASLRSRLALQFVDRWPLESCLEILAYCISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 DDLSSIKDAVLSCAVACDKEGWQYLFPVKDASLRSRLALQFVDRWPLESCLEILAYCISD 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 TAVQEGLKCELQRKLAELQVYQKILGLQSPPVWCDWQTLRSCCVEDPSTVMNMILEAQEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 TAVQEGLKCELQRKLAELQVYQKILGLQSPPVWCDWQTLRSCCVEDPSTVMNMILEAQEY 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 ELCEEWGCLYPIPREHLISLHQKHLLHLLERRDHDKALQLLRRIPDPTMCLEVTEQSLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ELCEEWGCLYPIPREHLISLHQKHLLHLLERRDHDKALQLLRRIPDPTMCLEVTEQSLDQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTSLATSHFLANYLTTHFYGQLTAVRHREIQALYVGSKILLTLPEQHRASYSHLSSNPLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 HTSLATSHFLANYLTTHFYGQLTAVRHREIQALYVGSKILLTLPEQHRASYSHLSSNPLF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 MLEQLLMNMKVDWATVAVQTLQQLLVGQEIGFTMDEVDSLLSRYAEKALDFPYPQREKRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MLEQLLMNMKVDWATVAVQTLQQLLVGQEIGFTMDEVDSLLSRYAEKALDFPYPQREKRS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 DSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLRERSFPPTQPSQEFVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 DSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLRERSFPPTQPSQEFVPP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 ATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENP 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 ARVCDQCYSYCNKDVPEEPSEKPEALDSSKSESPPYSFVVRVPKADEVEWILDLKEEENE ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: CCDS97 ARVCDQCYSYCNKDVPEEPSEKPEALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENE 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 LVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSKGLTNPEVDAGLLTDIMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 LVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSKGLTNPEVDAGLLTDIMK 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 QLLFSAKMMFVKAGQSQDLALCDSYISKVDVLNILVAAAYRHVPSLDQILQPAAVTRLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 QLLFSAKMMFVKAGQSQDLALCDSYISKVDVLNILVAAAYRHVPSLDQILQPAAVTRLRN 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 QLLEAEYYQLGVEVSTKTGLDTTGAWHAWGMACLKAGNLTAAREKFSRCLKPPFDLNQLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 QLLEAEYYQLGVEVSTKTGLDTTGAWHAWGMACLKAGNLTAAREKFSRCLKPPFDLNQLN 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 HGSRLVQDVVEYLESTVRPFVSLQDDDYFATLRELEATLRTQSLSLAVIPEGKIMNNTYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 HGSRLVQDVVEYLESTVRPFVSLQDDDYFATLRELEATLRTQSLSLAVIPEGKIMNNTYY 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 QECLFYLHNYSTNLAIISFYVRHSCLREALLHLLNKESPPEVFIEGIFQPSYKSGKLHTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 QECLFYLHNYSTNLAIISFYVRHSCLREALLHLLNKESPPEVFIEGIFQPSYKSGKLHTL 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA0 ENLLESIDPTLESWGKYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ENLLESIDPTLESWGKYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAK 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA0 SYTELGEKLSWLLKAKDHLKIYLQETSRSSGRKKTTFFRKKMTAADVSRHMNTLQLQMEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 SYTELGEKLSWLLKAKDHLKIYLQETSRSSGRKKTTFFRKKMTAADVSRHMNTLQLQMEV 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA0 TRFLHRCESAGTSQITTLPLPTLFGNNHMKMDVACKVMLGGKNVEDGFGIAFRVLQDFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 TRFLHRCESAGTSQITTLPLPTLFGNNHMKMDVACKVMLGGKNVEDGFGIAFRVLQDFQL 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KA0 DAAMTYCRAARQLVEKEKYSEIQQLLKCVSESGMAAKSDGDTILLNCLEAFKRIPPQELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 DAAMTYCRAARQLVEKEKYSEIQQLLKCVSESGMAAKSDGDTILLNCLEAFKRIPPQELE 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KA0 GLIQAIHNDDNKVRAYLICCKLRSAYLIAVKQEHSRATALVQQVQQAAKSSGDAVVQDIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GLIQAIHNDDNKVRAYLICCKLRSAYLIAVKQEHSRATALVQQVQQAAKSSGDAVVQDIC 2470 2480 2490 2500 2510 2520 2530 pF1KA0 AQWLLTSHPRGAHGPGSRK ::::::::::::::::::: CCDS97 AQWLLTSHPRGAHGPGSRK 2530 2539 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:34:24 2016 done: Wed Nov 2 18:34:26 2016 Total Scan time: 7.740 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]