Result of FASTA (omim) for pF1KA0322
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0322, 1606 aa
  1>>>pF1KA0322 1606 - 1606 aa - 1606 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.5911+/-0.000437; mu= 9.7275+/- 0.028
 mean_var=207.0146+/-41.358, 0's: 0 Z-trim(117.7): 273  B-trim: 210 in 2/52
 Lambda= 0.089140
 statistics sampled from 29619 (29925) to 29619 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.351), width:  16
 Scan time: 18.550

The best scores are:                                      opt bits E(85289)
NP_055867 (OMIM: 610384) E3 ubiquitin-protein liga (1606) 10761 1398.1       0
XP_016867375 (OMIM: 610384) PREDICTED: E3 ubiquiti (1606) 10761 1398.1       0
XP_011513522 (OMIM: 610384) PREDICTED: E3 ubiquiti (1607) 10749 1396.6       0
XP_016867374 (OMIM: 610384) PREDICTED: E3 ubiquiti (1607) 10749 1396.6       0
XP_005249722 (OMIM: 610384) PREDICTED: E3 ubiquiti (1607) 10749 1396.6       0
XP_006715734 (OMIM: 610384) PREDICTED: E3 ubiquiti (1607) 10707 1391.2       0
XP_016867373 (OMIM: 610384) PREDICTED: E3 ubiquiti (1638) 10704 1390.8       0
XP_006715733 (OMIM: 610384) PREDICTED: E3 ubiquiti (1608) 10695 1389.6       0
XP_016867372 (OMIM: 610384) PREDICTED: E3 ubiquiti (1639) 10692 1389.3       0
XP_016867371 (OMIM: 610384) PREDICTED: E3 ubiquiti (1639) 10692 1389.3       0
XP_011513524 (OMIM: 610384) PREDICTED: E3 ubiquiti (1586) 10611 1378.8       0
XP_011513526 (OMIM: 610384) PREDICTED: E3 ubiquiti (1586) 10611 1378.8       0
XP_011513525 (OMIM: 610384) PREDICTED: E3 ubiquiti (1586) 10611 1378.8       0
XP_011513527 (OMIM: 610384) PREDICTED: E3 ubiquiti (1480) 9705 1262.3       0
XP_011513528 (OMIM: 610384) PREDICTED: E3 ubiquiti (1437) 9498 1235.7       0
XP_016867379 (OMIM: 610384) PREDICTED: E3 ubiquiti (1356) 8971 1167.9       0
XP_016867378 (OMIM: 610384) PREDICTED: E3 ubiquiti (1572) 5332 699.9 4.3e-200
NP_001273988 (OMIM: 610384) E3 ubiquitin-protein l (1572) 5332 699.9 4.3e-200
XP_006715736 (OMIM: 610384) PREDICTED: E3 ubiquiti (1573) 5278 693.0 5.3e-198
XP_016867376 (OMIM: 610384) PREDICTED: E3 ubiquiti (1605) 5278 693.0 5.4e-198
XP_016867377 (OMIM: 610384) PREDICTED: E3 ubiquiti (1604) 5275 692.6  7e-198
XP_016881168 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 854) 1473 203.5 6.6e-51
NP_001138438 (OMIM: 606384) E3 ubiquitin-protein l ( 854) 1473 203.5 6.6e-51
NP_001138437 (OMIM: 606384) E3 ubiquitin-protein l ( 854) 1473 203.5 6.6e-51
NP_001138436 (OMIM: 606384) E3 ubiquitin-protein l ( 854) 1473 203.5 6.6e-51
XP_005266717 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 942) 1473 203.5 7.2e-51
NP_001138440 (OMIM: 606384) E3 ubiquitin-protein l ( 967) 1473 203.5 7.3e-51
NP_001138439 (OMIM: 606384) E3 ubiquitin-protein l ( 975) 1473 203.5 7.4e-51
XP_006722484 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 940) 1370 190.2 6.9e-47
XP_016881167 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 973) 1368 190.0 8.5e-47
NP_001138442 (OMIM: 606384) E3 ubiquitin-protein l ( 834) 1363 189.3 1.2e-46
NP_001138443 (OMIM: 606384) E3 ubiquitin-protein l ( 834) 1363 189.3 1.2e-46
XP_005266720 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 922) 1363 189.3 1.3e-46
NP_001138441 (OMIM: 606384) E3 ubiquitin-protein l ( 947) 1363 189.3 1.3e-46
NP_056092 (OMIM: 606384) E3 ubiquitin-protein liga ( 955) 1363 189.3 1.3e-46
NP_001316141 (OMIM: 602278) E3 ubiquitin-protein l ( 753) 1350 187.6 3.5e-46
XP_011519929 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 827) 1350 187.6 3.7e-46
XP_011519927 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 849) 1350 187.6 3.8e-46
XP_011519928 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 849) 1350 187.6 3.8e-46
XP_011519926 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 875) 1350 187.6 3.9e-46
NP_006145 (OMIM: 602278) E3 ubiquitin-protein liga ( 900) 1350 187.7   4e-46
NP_940682 (OMIM: 602278) E3 ubiquitin-protein liga (1247) 1350 187.8 5.1e-46
NP_001271269 (OMIM: 602278) E3 ubiquitin-protein l (1302) 1350 187.8 5.3e-46
NP_001271268 (OMIM: 602278) E3 ubiquitin-protein l (1303) 1350 187.8 5.3e-46
NP_001271267 (OMIM: 602278) E3 ubiquitin-protein l (1319) 1350 187.8 5.4e-46
XP_016881170 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 684) 1282 178.8 1.4e-43
XP_016881169 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 750) 1282 178.8 1.5e-43
XP_006722488 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 772) 1282 178.9 1.5e-43
XP_016881166 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 838) 1282 178.9 1.6e-43
XP_006722487 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 790) 1281 178.7 1.7e-43


>>NP_055867 (OMIM: 610384) E3 ubiquitin-protein ligase H  (1606 aa)
 initn: 10761 init1: 10761 opt: 10761  Z-score: 7486.5  bits: 1398.1 E(85289):    0
Smith-Waterman score: 10761; 99.9% identity (99.9% similar) in 1606 aa overlap (1-1606:1-1606)

               10        20        30        40        50        60
pF1KA0 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEEAA
       ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_055 SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      
pF1KA0 KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600      

>>XP_016867375 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1606 aa)
 initn: 10761 init1: 10761 opt: 10761  Z-score: 7486.5  bits: 1398.1 E(85289):    0
Smith-Waterman score: 10761; 99.9% identity (99.9% similar) in 1606 aa overlap (1-1606:1-1606)

               10        20        30        40        50        60
pF1KA0 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEEAA
       ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_016 SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      
pF1KA0 KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600      

>>XP_011513522 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1607 aa)
 initn: 8427 init1: 8427 opt: 10749  Z-score: 7478.1  bits: 1396.6 E(85289):    0
Smith-Waterman score: 10749; 99.9% identity (99.9% similar) in 1607 aa overlap (1-1606:1-1607)

               10        20        30        40        50        60
pF1KA0 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
              250       260       270       280       290       300

              310       320       330       340        350         
pF1KA0 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHP-DDEEISLSTEP
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPADDEEISLSTEP
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEEA
       :::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_011 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEA
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA0 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA0 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA0 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA0 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA0 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA0 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA0 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA0 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA0 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA0 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA0 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA0 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA0 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290      1300      1310         
pF1KA0 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
             1270      1280      1290      1300      1310      1320

    1320      1330      1340      1350      1360      1370         
pF1KA0 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KA0 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
             1390      1400      1410      1420      1430      1440

    1440      1450      1460      1470      1480      1490         
pF1KA0 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
             1450      1460      1470      1480      1490      1500

    1500      1510      1520      1530      1540      1550         
pF1KA0 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
             1510      1520      1530      1540      1550      1560

    1560      1570      1580      1590      1600      
pF1KA0 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600       

>>XP_016867374 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1607 aa)
 initn: 8427 init1: 8427 opt: 10749  Z-score: 7478.1  bits: 1396.6 E(85289):    0
Smith-Waterman score: 10749; 99.9% identity (99.9% similar) in 1607 aa overlap (1-1606:1-1607)

               10        20        30        40        50        60
pF1KA0 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
              250       260       270       280       290       300

              310       320       330       340        350         
pF1KA0 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHP-DDEEISLSTEP
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPADDEEISLSTEP
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEEA
       :::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEA
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA0 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA0 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA0 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA0 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA0 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA0 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA0 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA0 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA0 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA0 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA0 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA0 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA0 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290      1300      1310         
pF1KA0 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
             1270      1280      1290      1300      1310      1320

    1320      1330      1340      1350      1360      1370         
pF1KA0 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KA0 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
             1390      1400      1410      1420      1430      1440

    1440      1450      1460      1470      1480      1490         
pF1KA0 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
             1450      1460      1470      1480      1490      1500

    1500      1510      1520      1530      1540      1550         
pF1KA0 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
             1510      1520      1530      1540      1550      1560

    1560      1570      1580      1590      1600      
pF1KA0 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600       

>>XP_005249722 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1607 aa)
 initn: 8427 init1: 8427 opt: 10749  Z-score: 7478.1  bits: 1396.6 E(85289):    0
Smith-Waterman score: 10749; 99.9% identity (99.9% similar) in 1607 aa overlap (1-1606:1-1607)

               10        20        30        40        50        60
pF1KA0 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
              250       260       270       280       290       300

              310       320       330       340        350         
pF1KA0 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHP-DDEEISLSTEP
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPADDEEISLSTEP
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEEA
       :::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_005 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEA
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA0 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA0 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA0 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA0 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA0 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA0 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA0 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA0 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA0 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA0 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA0 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA0 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA0 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290      1300      1310         
pF1KA0 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
             1270      1280      1290      1300      1310      1320

    1320      1330      1340      1350      1360      1370         
pF1KA0 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KA0 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
             1390      1400      1410      1420      1430      1440

    1440      1450      1460      1470      1480      1490         
pF1KA0 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
             1450      1460      1470      1480      1490      1500

    1500      1510      1520      1530      1540      1550         
pF1KA0 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
             1510      1520      1530      1540      1550      1560

    1560      1570      1580      1590      1600      
pF1KA0 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600       

>>XP_006715734 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1607 aa)
 initn: 10707 init1: 10707 opt: 10707  Z-score: 7448.9  bits: 1391.2 E(85289):    0
Smith-Waterman score: 10707; 99.8% identity (99.9% similar) in 1600 aa overlap (7-1606:8-1607)

                10        20        30        40        50         
pF1KA0  MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHD
              ..:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MICAQARAAKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHD
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KA0 GVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDE
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KA0 VLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTV
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA0 KNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHS
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA0 IFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLG
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA0 KLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEP
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEEA
       :::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_006 ESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEA
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAP
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA0 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPV
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA0 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDG
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA0 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESD
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KA0 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRF
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA0 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGH
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA0 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARI
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA0 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEE
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA0 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFIT
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA0 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLE
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA0 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEA
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA0 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSL
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA0 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPR
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA0 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHL
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290      1300      1310         
pF1KA0 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSA
             1270      1280      1290      1300      1310      1320

    1320      1330      1340      1350      1360      1370         
pF1KA0 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSD
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KA0 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEY
             1390      1400      1410      1420      1430      1440

    1440      1450      1460      1470      1480      1490         
pF1KA0 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNT
             1450      1460      1470      1480      1490      1500

    1500      1510      1520      1530      1540      1550         
pF1KA0 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCI
             1510      1520      1530      1540      1550      1560

    1560      1570      1580      1590      1600      
pF1KA0 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600       

>>XP_016867373 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1638 aa)
 initn: 10704 init1: 10704 opt: 10704  Z-score: 7446.7  bits: 1390.8 E(85289):    0
Smith-Waterman score: 10704; 99.8% identity (99.9% similar) in 1600 aa overlap (7-1606:39-1638)

                                       10        20        30      
pF1KA0                         MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCK
                                     .. :::::::::::::::::::::::::::
XP_016 VKDPGSVVVQGVSKQVARSAFLISRLTPAVAITNLYQNRFLGLAAMASPSRNSQSRRRCK
       10        20        30        40        50        60        

         40        50        60        70        80        90      
pF1KA0 EPLRYSYNPDQFHNMDLRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLRYSYNPDQFHNMDLRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDL
       70        80        90       100       110       120        

        100       110       120       130       140       150      
pF1KA0 VIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPET
      130       140       150       160       170       180        

        160       170       180       190       200       210      
pF1KA0 KICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMG
      190       200       210       220       230       240        

        220       230       240       250       260       270      
pF1KA0 LKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPT
      250       260       270       280       290       300        

        280       290       300       310       320       330      
pF1KA0 DVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQL
      310       320       330       340       350       360        

        340       350       360       370       380       390      
pF1KA0 QFRFEITSSIHPDDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFRFEITSSIHPDDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQL
      370       380       390       400       410       420        

        400       410       420       430       440       450      
pF1KA0 GEGSVPDRPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAE
       ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEGSVPDGPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAE
      430       440       450       460       470       480        

        460       470       480       490       500       510      
pF1KA0 ELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLE
      490       500       510       520       530       540        

        520       530       540       550       560       570      
pF1KA0 QGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGG
      550       560       570       580       590       600        

        580       590       600       610       620       630      
pF1KA0 SAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGH
      610       620       630       640       650       660        

        640       650       660       670       680       690      
pF1KA0 FPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSS
      670       680       690       700       710       720        

        700       710       720       730       740       750      
pF1KA0 CYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSP
      730       740       750       760       770       780        

        760       770       780       790       800       810      
pF1KA0 ELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPS
      790       800       810       820       830       840        

        820       830       840       850       860       870      
pF1KA0 LRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQ
      850       860       870       880       890       900        

        880       890       900       910       920       930      
pF1KA0 QMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREG
      910       920       930       940       950       960        

        940       950       960       970       980       990      
pF1KA0 SLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARN
      970       980       990      1000      1010      1020        

       1000      1010      1020      1030      1040      1050      
pF1KA0 FERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNG
     1030      1040      1050      1060      1070      1080        

       1060      1070      1080      1090      1100      1110      
pF1KA0 RLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYN
     1090      1100      1110      1120      1130      1140        

       1120      1130      1140      1150      1160      1170      
pF1KA0 DKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLF
     1150      1160      1170      1180      1190      1200        

       1180      1190      1200      1210      1220      1230      
pF1KA0 EEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYR
     1210      1220      1230      1240      1250      1260        

       1240      1250      1260      1270      1280      1290      
pF1KA0 KLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPS
     1270      1280      1290      1300      1310      1320        

       1300      1310      1320      1330      1340      1350      
pF1KA0 REFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQY
     1330      1340      1350      1360      1370      1380        

       1360      1370      1380      1390      1400      1410      
pF1KA0 LLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQ
     1390      1400      1410      1420      1430      1440        

       1420      1430      1440      1450      1460      1470      
pF1KA0 VTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFD
     1450      1460      1470      1480      1490      1500        

       1480      1490      1500      1510      1520      1530      
pF1KA0 ARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTG
     1510      1520      1530      1540      1550      1560        

       1540      1550      1560      1570      1580      1590      
pF1KA0 TSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTA
     1570      1580      1590      1600      1610      1620        

       1600      
pF1KA0 VEETSTFGLE
       ::::::::::
XP_016 VEETSTFGLE
     1630        

>>XP_006715733 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1608 aa)
 initn: 8427 init1: 8427 opt: 10695  Z-score: 7440.6  bits: 1389.6 E(85289):    0
Smith-Waterman score: 10695; 99.8% identity (99.9% similar) in 1601 aa overlap (7-1606:8-1608)

                10        20        30        40        50         
pF1KA0  MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHD
              ..:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MICAQARAAKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHD
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KA0 GVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDE
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KA0 VLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTV
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA0 KNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHS
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA0 IFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLG
              250       260       270       280       290       300

     300       310       320       330       340        350        
pF1KA0 KLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHP-DDEEISLSTE
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_006 KLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPADDEEISLSTE
              310       320       330       340       350       360

      360       370       380       390       400       410        
pF1KA0 PESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDRPGNQSIELSRPAEE
       ::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_006 PESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEE
              370       380       390       400       410       420

      420       430       440       450       460       470        
pF1KA0 AAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEA
              430       440       450       460       470       480

      480       490       500       510       520       530        
pF1KA0 PASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLP
              490       500       510       520       530       540

      540       550       560       570       580       590        
pF1KA0 VSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKD
              550       560       570       580       590       600

      600       610       620       630       640       650        
pF1KA0 GLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSES
              610       620       630       640       650       660

      660       670       680       690       700       710        
pF1KA0 DSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTR
              670       680       690       700       710       720

      720       730       740       750       760       770        
pF1KA0 FSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSG
              730       740       750       760       770       780

      780       790       800       810       820       830        
pF1KA0 HVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEAR
              790       800       810       820       830       840

      840       850       860       870       880       890        
pF1KA0 IDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSE
              850       860       870       880       890       900

      900       910       920       930       940       950        
pF1KA0 EDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFI
              910       920       930       940       950       960

      960       970       980       990      1000      1010        
pF1KA0 TNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRL
              970       980       990      1000      1010      1020

     1020      1030      1040      1050      1060      1070        
pF1KA0 ELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGE
             1030      1040      1050      1060      1070      1080

     1080      1090      1100      1110      1120      1130        
pF1KA0 ASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPS
             1090      1100      1110      1120      1130      1140

     1140      1150      1160      1170      1180      1190        
pF1KA0 LARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSP
             1150      1160      1170      1180      1190      1200

     1200      1210      1220      1230      1240      1250        
pF1KA0 RCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDH
             1210      1220      1230      1240      1250      1260

     1260      1270      1280      1290      1300      1310        
pF1KA0 LLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYS
             1270      1280      1290      1300      1310      1320

     1320      1330      1340      1350      1360      1370        
pF1KA0 ANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLS
             1330      1340      1350      1360      1370      1380

     1380      1390      1400      1410      1420      1430        
pF1KA0 DLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKE
             1390      1400      1410      1420      1430      1440

     1440      1450      1460      1470      1480      1490        
pF1KA0 YIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNN
             1450      1460      1470      1480      1490      1500

     1500      1510      1520      1530      1540      1550        
pF1KA0 TEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFC
             1510      1520      1530      1540      1550      1560

     1560      1570      1580      1590      1600      
pF1KA0 IEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
       ::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
             1570      1580      1590      1600        

>>XP_016867372 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1639 aa)
 initn: 8427 init1: 8427 opt: 10692  Z-score: 7438.4  bits: 1389.3 E(85289):    0
Smith-Waterman score: 10692; 99.7% identity (99.8% similar) in 1601 aa overlap (7-1606:39-1639)

                                       10        20        30      
pF1KA0                         MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCK
                                     .. :::::::::::::::::::::::::::
XP_016 VKDPGSVVVQGVSKQVARSAFLISRLTPAVAITNLYQNRFLGLAAMASPSRNSQSRRRCK
       10        20        30        40        50        60        

         40        50        60        70        80        90      
pF1KA0 EPLRYSYNPDQFHNMDLRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLRYSYNPDQFHNMDLRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDL
       70        80        90       100       110       120        

        100       110       120       130       140       150      
pF1KA0 VIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPET
      130       140       150       160       170       180        

        160       170       180       190       200       210      
pF1KA0 KICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMG
      190       200       210       220       230       240        

        220       230       240       250       260       270      
pF1KA0 LKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPT
      250       260       270       280       290       300        

        280       290       300       310       320       330      
pF1KA0 DVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQL
      310       320       330       340       350       360        

        340        350       360       370       380       390     
pF1KA0 QFRFEITSSIHP-DDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQ
       :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFRFEITSSIHPADDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQ
      370       380       390       400       410       420        

         400       410       420       430       440       450     
pF1KA0 LGEGSVPDRPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSA
       :::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEGSVPDGPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSA
      430       440       450       460       470       480        

         460       470       480       490       500       510     
pF1KA0 EELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTL
      490       500       510       520       530       540        

         520       530       540       550       560       570     
pF1KA0 EQGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQG
      550       560       570       580       590       600        

         580       590       600       610       620       630     
pF1KA0 GSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGG
      610       620       630       640       650       660        

         640       650       660       670       680       690     
pF1KA0 HFPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSS
      670       680       690       700       710       720        

         700       710       720       730       740       750     
pF1KA0 SCYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQS
      730       740       750       760       770       780        

         760       770       780       790       800       810     
pF1KA0 PELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLP
      790       800       810       820       830       840        

         820       830       840       850       860       870     
pF1KA0 SLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSI
      850       860       870       880       890       900        

         880       890       900       910       920       930     
pF1KA0 QQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRRE
      910       920       930       940       950       960        

         940       950       960       970       980       990     
pF1KA0 GSLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDAR
      970       980       990      1000      1010      1020        

        1000      1010      1020      1030      1040      1050     
pF1KA0 NFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQN
     1030      1040      1050      1060      1070      1080        

        1060      1070      1080      1090      1100      1110     
pF1KA0 GRLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAY
     1090      1100      1110      1120      1130      1140        

        1120      1130      1140      1150      1160      1170     
pF1KA0 NDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSL
     1150      1160      1170      1180      1190      1200        

        1180      1190      1200      1210      1220      1230     
pF1KA0 FEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFY
     1210      1220      1230      1240      1250      1260        

        1240      1250      1260      1270      1280      1290     
pF1KA0 RKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGP
     1270      1280      1290      1300      1310      1320        

        1300      1310      1320      1330      1340      1350     
pF1KA0 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ
     1330      1340      1350      1360      1370      1380        

        1360      1370      1380      1390      1400      1410     
pF1KA0 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFG
     1390      1400      1410      1420      1430      1440        

        1420      1430      1440      1450      1460      1470     
pF1KA0 QVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVF
     1450      1460      1470      1480      1490      1500        

        1480      1490      1500      1510      1520      1530     
pF1KA0 DARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVT
     1510      1520      1530      1540      1550      1560        

        1540      1550      1560      1570      1580      1590     
pF1KA0 GTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLT
     1570      1580      1590      1600      1610      1620        

        1600      
pF1KA0 AVEETSTFGLE
       :::::::::::
XP_016 AVEETSTFGLE
     1630         

>>XP_016867371 (OMIM: 610384) PREDICTED: E3 ubiquitin-pr  (1639 aa)
 initn: 8427 init1: 8427 opt: 10692  Z-score: 7438.4  bits: 1389.3 E(85289):    0
Smith-Waterman score: 10692; 99.7% identity (99.8% similar) in 1601 aa overlap (7-1606:39-1639)

                                       10        20        30      
pF1KA0                         MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCK
                                     .. :::::::::::::::::::::::::::
XP_016 VKDPGSVVVQGVSKQVARSAFLISRLTPAVAITNLYQNRFLGLAAMASPSRNSQSRRRCK
       10        20        30        40        50        60        

         40        50        60        70        80        90      
pF1KA0 EPLRYSYNPDQFHNMDLRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLRYSYNPDQFHNMDLRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDL
       70        80        90       100       110       120        

        100       110       120       130       140       150      
pF1KA0 VIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPET
      130       140       150       160       170       180        

        160       170       180       190       200       210      
pF1KA0 KICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMG
      190       200       210       220       230       240        

        220       230       240       250       260       270      
pF1KA0 LKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPT
      250       260       270       280       290       300        

        280       290       300       310       320       330      
pF1KA0 DVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQL
      310       320       330       340       350       360        

        340        350       360       370       380       390     
pF1KA0 QFRFEITSSIHP-DDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQ
       :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFRFEITSSIHPADDEEISLSTEPESAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQ
      370       380       390       400       410       420        

         400       410       420       430       440       450     
pF1KA0 LGEGSVPDRPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSA
       :::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEGSVPDGPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSA
      430       440       450       460       470       480        

         460       470       480       490       500       510     
pF1KA0 EELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTL
      490       500       510       520       530       540        

         520       530       540       550       560       570     
pF1KA0 EQGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQG
      550       560       570       580       590       600        

         580       590       600       610       620       630     
pF1KA0 GSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGG
      610       620       630       640       650       660        

         640       650       660       670       680       690     
pF1KA0 HFPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSS
      670       680       690       700       710       720        

         700       710       720       730       740       750     
pF1KA0 SCYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQS
      730       740       750       760       770       780        

         760       770       780       790       800       810     
pF1KA0 PELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLP
      790       800       810       820       830       840        

         820       830       840       850       860       870     
pF1KA0 SLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSI
      850       860       870       880       890       900        

         880       890       900       910       920       930     
pF1KA0 QQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRRE
      910       920       930       940       950       960        

         940       950       960       970       980       990     
pF1KA0 GSLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDAR
      970       980       990      1000      1010      1020        

        1000      1010      1020      1030      1040      1050     
pF1KA0 NFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQN
     1030      1040      1050      1060      1070      1080        

        1060      1070      1080      1090      1100      1110     
pF1KA0 GRLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAY
     1090      1100      1110      1120      1130      1140        

        1120      1130      1140      1150      1160      1170     
pF1KA0 NDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSL
     1150      1160      1170      1180      1190      1200        

        1180      1190      1200      1210      1220      1230     
pF1KA0 FEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFY
     1210      1220      1230      1240      1250      1260        

        1240      1250      1260      1270      1280      1290     
pF1KA0 RKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGP
     1270      1280      1290      1300      1310      1320        

        1300      1310      1320      1330      1340      1350     
pF1KA0 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ
     1330      1340      1350      1360      1370      1380        

        1360      1370      1380      1390      1400      1410     
pF1KA0 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFG
     1390      1400      1410      1420      1430      1440        

        1420      1430      1440      1450      1460      1470     
pF1KA0 QVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVF
     1450      1460      1470      1480      1490      1500        

        1480      1490      1500      1510      1520      1530     
pF1KA0 DARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVT
     1510      1520      1530      1540      1550      1560        

        1540      1550      1560      1570      1580      1590     
pF1KA0 GTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLT
     1570      1580      1590      1600      1610      1620        

        1600      
pF1KA0 AVEETSTFGLE
       :::::::::::
XP_016 AVEETSTFGLE
     1630         




1606 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 09:18:47 2016 done: Thu Nov  3 09:18:50 2016
 Total Scan time: 18.550 Total Display time:  0.830

Function used was FASTA [36.3.4 Apr, 2011]
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