Result of FASTA (omim) for
pF1KA0333
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0333, 1189 aa
1>>>pF1KA0333 1189 - 1189 aa - 1189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1475+/-0.000419; mu= -4.3118+/- 0.026
mean_var=330.4884+/-66.870, 0's: 0 Z-trim(121.1): 67 B-trim: 106 in 1/59
Lambda= 0.070550
statistics sampled from 37247 (37319) to 37247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.438), width: 16
Scan time: 15.060
The best scores are: opt bits E(85289)
NP_542987 (OMIM: 604140) death-inducer obliterator (1189) 7977 826.8 0
NP_001180299 (OMIM: 604140) death-inducer oblitera (1189) 7977 826.8 0
XP_011526811 (OMIM: 604140) PREDICTED: death-induc (2240) 7917 820.9 0
NP_001180298 (OMIM: 604140) death-inducer oblitera (2240) 7917 820.9 0
NP_149072 (OMIM: 604140) death-inducer obliterator (2240) 7917 820.9 0
XP_011526810 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526807 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526806 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526809 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526808 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
NP_071388 (OMIM: 604140) death-inducer obliterator ( 562) 3608 381.9 6.4e-105
NP_542986 (OMIM: 604140) death-inducer obliterator ( 562) 3608 381.9 6.4e-105
XP_005248760 (OMIM: 607789) PREDICTED: PHD finger (1308) 644 80.4 8.1e-14
XP_016866115 (OMIM: 607789) PREDICTED: PHD finger (1308) 644 80.4 8.1e-14
XP_005248759 (OMIM: 607789) PREDICTED: PHD finger (1951) 644 80.6 1.1e-13
NP_001277188 (OMIM: 607789) PHD finger protein 3 i (1951) 644 80.6 1.1e-13
XP_006715489 (OMIM: 607789) PREDICTED: PHD finger (2039) 644 80.6 1.1e-13
XP_005248758 (OMIM: 607789) PREDICTED: PHD finger (2039) 644 80.6 1.1e-13
NP_055968 (OMIM: 607789) PHD finger protein 3 isof (2039) 644 80.6 1.1e-13
XP_011533950 (OMIM: 607789) PREDICTED: PHD finger (2048) 644 80.6 1.2e-13
>>NP_542987 (OMIM: 604140) death-inducer obliterator 1 i (1189 aa)
initn: 7977 init1: 7977 opt: 7977 Z-score: 4403.3 bits: 826.8 E(85289): 0
Smith-Waterman score: 7977; 100.0% identity (100.0% similar) in 1189 aa overlap (1-1189:1-1189)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
1150 1160 1170 1180
>>NP_001180299 (OMIM: 604140) death-inducer obliterator (1189 aa)
initn: 7977 init1: 7977 opt: 7977 Z-score: 4403.3 bits: 826.8 E(85289): 0
Smith-Waterman score: 7977; 100.0% identity (100.0% similar) in 1189 aa overlap (1-1189:1-1189)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
1150 1160 1170 1180
>>XP_011526811 (OMIM: 604140) PREDICTED: death-inducer o (2240 aa)
initn: 7917 init1: 7917 opt: 7917 Z-score: 4366.5 bits: 820.9 E(85289): 0
Smith-Waterman score: 7917; 100.0% identity (100.0% similar) in 1181 aa overlap (1-1181:1-1181)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::::::::::::::::::::::::::
XP_011 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
1150 1160 1170 1180 1190 1200
XP_011 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
1210 1220 1230 1240 1250 1260
>>NP_001180298 (OMIM: 604140) death-inducer obliterator (2240 aa)
initn: 7917 init1: 7917 opt: 7917 Z-score: 4366.5 bits: 820.9 E(85289): 0
Smith-Waterman score: 7917; 100.0% identity (100.0% similar) in 1181 aa overlap (1-1181:1-1181)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::::::::::::::::::::::::::
NP_001 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
1150 1160 1170 1180 1190 1200
NP_001 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
1210 1220 1230 1240 1250 1260
>>NP_149072 (OMIM: 604140) death-inducer obliterator 1 i (2240 aa)
initn: 7917 init1: 7917 opt: 7917 Z-score: 4366.5 bits: 820.9 E(85289): 0
Smith-Waterman score: 7917; 100.0% identity (100.0% similar) in 1181 aa overlap (1-1181:1-1181)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::::::::::::::::::::::::::
NP_149 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
1150 1160 1170 1180 1190 1200
NP_149 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
1210 1220 1230 1240 1250 1260
>>XP_011526810 (OMIM: 604140) PREDICTED: death-inducer o (2276 aa)
initn: 7903 init1: 5276 opt: 5276 Z-score: 2913.6 bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
:::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
1150 1160 1170 1180 1190 1200
1170 1180
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
1210 1220 1230 1240 1250 1260
>>XP_011526807 (OMIM: 604140) PREDICTED: death-inducer o (2276 aa)
initn: 7903 init1: 5276 opt: 5276 Z-score: 2913.6 bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
:::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
1150 1160 1170 1180 1190 1200
1170 1180
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
1210 1220 1230 1240 1250 1260
>>XP_011526806 (OMIM: 604140) PREDICTED: death-inducer o (2276 aa)
initn: 7903 init1: 5276 opt: 5276 Z-score: 2913.6 bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
:::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
1150 1160 1170 1180 1190 1200
1170 1180
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
1210 1220 1230 1240 1250 1260
>>XP_011526809 (OMIM: 604140) PREDICTED: death-inducer o (2276 aa)
initn: 7903 init1: 5276 opt: 5276 Z-score: 2913.6 bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
:::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
1150 1160 1170 1180 1190 1200
1170 1180
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
1210 1220 1230 1240 1250 1260
>>XP_011526808 (OMIM: 604140) PREDICTED: death-inducer o (2276 aa)
initn: 7903 init1: 5276 opt: 5276 Z-score: 2913.6 bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)
10 20 30 40 50 60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
310 320 330 340 350 360
370 380
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
:::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
1150 1160 1170 1180 1190 1200
1170 1180
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR
:::::::::::::::::
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
1210 1220 1230 1240 1250 1260
1189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:21:52 2016 done: Thu Nov 3 09:21:54 2016
Total Scan time: 15.060 Total Display time: 0.550
Function used was FASTA [36.3.4 Apr, 2011]