FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0365, 1082 aa 1>>>pF1KA0365 1082 - 1082 aa - 1082 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5376+/-0.000399; mu= 9.2386+/- 0.025 mean_var=207.0085+/-41.542, 0's: 0 Z-trim(119.3): 42 B-trim: 39 in 1/55 Lambda= 0.089142 statistics sampled from 33190 (33232) to 33190 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.39), width: 16 Scan time: 17.380 The best scores are: opt bits E(85289) NP_001017392 (OMIM: 607993) SURP and G-patch domai (1082) 7273 948.8 0 NP_055699 (OMIM: 607993) SURP and G-patch domain-c (1082) 7273 948.8 0 NP_001308626 (OMIM: 607993) SURP and G-patch domai (1082) 7273 948.8 0 XP_016881626 (OMIM: 607993) PREDICTED: SURP and G- (1082) 7273 948.8 0 NP_001308627 (OMIM: 607993) SURP and G-patch domai (1096) 7273 948.8 0 NP_001308628 (OMIM: 607993) SURP and G-patch domai (1096) 7273 948.8 0 XP_005260059 (OMIM: 607992) PREDICTED: SURP and G- ( 435) 269 47.8 0.00017 XP_011526457 (OMIM: 607992) PREDICTED: SURP and G- ( 435) 269 47.8 0.00017 >>NP_001017392 (OMIM: 607993) SURP and G-patch domain-co (1082 aa) initn: 7273 init1: 7273 opt: 7273 Z-score: 5064.5 bits: 948.8 E(85289): 0 Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1082 aa overlap (1-1082:1-1082) 10 20 30 40 50 60 pF1KA0 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA 1030 1040 1050 1060 1070 1080 pF1KA0 NK :: NP_001 NK >>NP_055699 (OMIM: 607993) SURP and G-patch domain-conta (1082 aa) initn: 7273 init1: 7273 opt: 7273 Z-score: 5064.5 bits: 948.8 E(85289): 0 Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1082 aa overlap (1-1082:1-1082) 10 20 30 40 50 60 pF1KA0 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA 1030 1040 1050 1060 1070 1080 pF1KA0 NK :: NP_055 NK >>NP_001308626 (OMIM: 607993) SURP and G-patch domain-co (1082 aa) initn: 7273 init1: 7273 opt: 7273 Z-score: 5064.5 bits: 948.8 E(85289): 0 Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1082 aa overlap (1-1082:1-1082) 10 20 30 40 50 60 pF1KA0 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA 1030 1040 1050 1060 1070 1080 pF1KA0 NK :: NP_001 NK >>XP_016881626 (OMIM: 607993) PREDICTED: SURP and G-patc (1082 aa) initn: 7273 init1: 7273 opt: 7273 Z-score: 5064.5 bits: 948.8 E(85289): 0 Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1082 aa overlap (1-1082:1-1082) 10 20 30 40 50 60 pF1KA0 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRA 1030 1040 1050 1060 1070 1080 pF1KA0 NK :: XP_016 NK >>NP_001308627 (OMIM: 607993) SURP and G-patch domain-co (1096 aa) initn: 7273 init1: 7273 opt: 7273 Z-score: 5064.4 bits: 948.8 E(85289): 0 Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1082 aa overlap (1-1082:15-1096) 10 20 30 40 pF1KA0 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAV :::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSPPRAAAAAGQNNMAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 PRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 CGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGP 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 SAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 GKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 GTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 FSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNML 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 LDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLA 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 LALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGRE 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 YIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 VGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRG 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 ADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSS 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 GTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDIS 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 EAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSA 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 FKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELE 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 SPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGT 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 CFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQ 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 QKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDV 1030 1040 1050 1060 1070 1080 1070 1080 pF1KA0 FRQRMMQMYRHKRANK :::::::::::::::: NP_001 FRQRMMQMYRHKRANK 1090 >>NP_001308628 (OMIM: 607993) SURP and G-patch domain-co (1096 aa) initn: 7273 init1: 7273 opt: 7273 Z-score: 5064.4 bits: 948.8 E(85289): 0 Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1082 aa overlap (1-1082:15-1096) 10 20 30 40 pF1KA0 MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAV :::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSPPRAAAAAGQNNMAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 PRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 CGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGP 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 SAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA0 GKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA0 GTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA0 FSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNML 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA0 LDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLA 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA0 LALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGRE 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA0 YIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA0 VGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRG 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA0 ADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSS 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA0 GTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDIS 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA0 EAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSA 790 800 810 820 830 840 830 840 850 860 870 880 pF1KA0 FKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELE 850 860 870 880 890 900 890 900 910 920 930 940 pF1KA0 SPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGT 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KA0 CFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQ 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KA0 QKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDV 1030 1040 1050 1060 1070 1080 1070 1080 pF1KA0 FRQRMMQMYRHKRANK :::::::::::::::: NP_001 FRQRMMQMYRHKRANK 1090 >>XP_005260059 (OMIM: 607992) PREDICTED: SURP and G-patc (435 aa) initn: 511 init1: 185 opt: 269 Z-score: 201.8 bits: 47.8 E(85289): 0.00017 Smith-Waterman score: 329; 23.9% identity (51.4% similar) in 477 aa overlap (611-1078:5-423) 590 600 610 620 630 640 pF1KA0 RADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRM :..::. :: :.:: :. ::. :.::... XP_005 MEDYKDNPAFAFLHDKNSREFLYYRKKVAEIRKE 10 20 30 650 660 670 680 690 700 pF1KA0 SENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGT ... ..:.:: . . .. :.:: .:: . : ... . . :. . . XP_005 AQKSQAASQKVSPPE--------DEEVKNLAEKLARFIADGGPEVETIALQNNRENQAFS 40 50 60 70 80 710 720 730 740 750 760 pF1KA0 QTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKP .. :.. .. . .:: : : ::: : . ..: :: : XP_005 FLYEPNSQGYKYYRQKLEEFRKAKASSTGSFTA-----PDP-GLKRKSPPEALSGSLPPA 90 100 110 120 130 140 770 780 790 800 810 pF1KA0 AGVDISEAPQ-TSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFL . : .: : : :.: . :... . .. ::: :.... : .. XP_005 TTCPASSTPAPTIIPAPAAPGKPASAATVKRKRK--SRWGPE------EDKVELPPAELV 150 160 170 180 190 820 830 840 850 860 870 pF1KA0 H-DQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEP . : ..: . .: .: ..: .: .: . . .:.. . .. .. : XP_005 QRDVDASPSPL---SVQDLKGLGYEKGKPVGL-VGVTELSDAQKKQLKEQQEMQQMYDMI 200 210 220 230 240 880 890 900 910 920 930 pF1KA0 PPREAELESPEVMPE---EEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAG .. ... ... : .. . :. ::. . :. . . : ::. XP_005 MQHKRAMQDMQLLWEKAVQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQ---- 250 260 270 280 290 300 940 950 960 970 980 990 pF1KA0 APALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSK :.. . : : .: . : .. : : . ... XP_005 ---LTKMGRGKHF-----------IGDFLPPDEL-----EKFMETF---------KALKE 310 320 330 1000 1010 1020 1030 1040 1050 pF1KA0 KKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPS-EGEGLGA ..: .. . ::: .:.:.:::.:::::::.:::: :.::..::. :: . .: :.: XP_005 GREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSEGQGIKNPVNKGTTTVDGAGFGI 340 350 360 370 380 390 1060 1070 1080 pF1KA0 D--GQEHKEDT-FDVFRQRMMQMYRHKRANK : .. ::: ...::.::: :: . XP_005 DRPAELSKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY 400 410 420 430 >>XP_011526457 (OMIM: 607992) PREDICTED: SURP and G-patc (435 aa) initn: 511 init1: 185 opt: 269 Z-score: 201.8 bits: 47.8 E(85289): 0.00017 Smith-Waterman score: 329; 23.9% identity (51.4% similar) in 477 aa overlap (611-1078:5-423) 590 600 610 620 630 640 pF1KA0 RADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRM :..::. :: :.:: :. ::. :.::... XP_011 MEDYKDNPAFAFLHDKNSREFLYYRKKVAEIRKE 10 20 30 650 660 670 680 690 700 pF1KA0 SENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGT ... ..:.:: . . .. :.:: .:: . : ... . . :. . . XP_011 AQKSQAASQKVSPPE--------DEEVKNLAEKLARFIADGGPEVETIALQNNRENQAFS 40 50 60 70 80 710 720 730 740 750 760 pF1KA0 QTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKP .. :.. .. . .:: : : ::: : . ..: :: : XP_011 FLYEPNSQGYKYYRQKLEEFRKAKASSTGSFTA-----PDP-GLKRKSPPEALSGSLPPA 90 100 110 120 130 140 770 780 790 800 810 pF1KA0 AGVDISEAPQ-TSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFL . : .: : : :.: . :... . .. ::: :.... : .. XP_011 TTCPASSTPAPTIIPAPAAPGKPASAATVKRKRK--SRWGPE------EDKVELPPAELV 150 160 170 180 190 820 830 840 850 860 870 pF1KA0 H-DQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEP . : ..: . .: .: ..: .: .: . . .:.. . .. .. : XP_011 QRDVDASPSPL---SVQDLKGLGYEKGKPVGL-VGVTELSDAQKKQLKEQQEMQQMYDMI 200 210 220 230 240 880 890 900 910 920 930 pF1KA0 PPREAELESPEVMPE---EEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAG .. ... ... : .. . :. ::. . :. . . : ::. XP_011 MQHKRAMQDMQLLWEKAVQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQ---- 250 260 270 280 290 300 940 950 960 970 980 990 pF1KA0 APALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSK :.. . : : .: . : .. : : . ... XP_011 ---LTKMGRGKHF-----------IGDFLPPDEL-----EKFMETF---------KALKE 310 320 330 1000 1010 1020 1030 1040 1050 pF1KA0 KKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPS-EGEGLGA ..: .. . ::: .:.:.:::.:::::::.:::: :.::..::. :: . .: :.: XP_011 GREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSEGQGIKNPVNKGTTTVDGAGFGI 340 350 360 370 380 390 1060 1070 1080 pF1KA0 D--GQEHKEDT-FDVFRQRMMQMYRHKRANK : .. ::: ...::.::: :: . XP_011 DRPAELSKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY 400 410 420 430 1082 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:26:48 2016 done: Thu Nov 3 09:26:50 2016 Total Scan time: 17.380 Total Display time: 0.380 Function used was FASTA [36.3.4 Apr, 2011]