Result of FASTA (omim) for
pF1KA0370
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0370, 1125 aa
1>>>pF1KA0370 1125 - 1125 aa - 1125 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8060+/-0.000414; mu= 19.3197+/- 0.026
mean_var=71.1333+/-14.279, 0's: 0 Z-trim(110.2): 23 B-trim: 51 in 1/53
Lambda= 0.152068
statistics sampled from 18515 (18524) to 18515 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.217), width: 16
Scan time: 14.930
The best scores are: opt bits E(85289)
NP_055986 (OMIM: 608411) exportin-6 isoform 2 [Hom (1125) 7350 1622.6 0
NP_001257869 (OMIM: 608411) exportin-6 isoform 1 [ (1111) 7273 1605.7 0
XP_005255254 (OMIM: 608411) PREDICTED: exportin-6 (1051) 6868 1516.9 0
XP_005255255 (OMIM: 608411) PREDICTED: exportin-6 ( 951) 6112 1351.0 0
XP_005255256 (OMIM: 608411) PREDICTED: exportin-6 ( 780) 4939 1093.6 0
XP_011544074 (OMIM: 608411) PREDICTED: exportin-6 ( 719) 4664 1033.3 0
>>NP_055986 (OMIM: 608411) exportin-6 isoform 2 [Homo sa (1125 aa)
initn: 7350 init1: 7350 opt: 7350 Z-score: 8705.3 bits: 1622.6 E(85289): 0
Smith-Waterman score: 7350; 100.0% identity (100.0% similar) in 1125 aa overlap (1-1125:1-1125)
10 20 30 40 50 60
pF1KA0 MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 FFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 SVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 AMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KA0 KSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL
:::::::::::::::::::::::::::::::::::::::::::::
NP_055 KSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL
1090 1100 1110 1120
>>NP_001257869 (OMIM: 608411) exportin-6 isoform 1 [Homo (1111 aa)
initn: 7273 init1: 7273 opt: 7273 Z-score: 8614.1 bits: 1605.7 E(85289): 0
Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1111 aa overlap (15-1125:1-1111)
10 20 30 40 50 60
pF1KA0 MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYV
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYV
10 20 30 40
70 80 90 100 110 120
pF1KA0 MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 ESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 SGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLN
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDA
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQV
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 LVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDD
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 TKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLS
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 FFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVV
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 QEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLA
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 SVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRT
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 AMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQ
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120
pF1KA0 KSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL
1070 1080 1090 1100 1110
>>XP_005255254 (OMIM: 608411) PREDICTED: exportin-6 isof (1051 aa)
initn: 6868 init1: 6868 opt: 6868 Z-score: 8134.3 bits: 1516.9 E(85289): 0
Smith-Waterman score: 6868; 100.0% identity (100.0% similar) in 1051 aa overlap (75-1125:1-1051)
50 60 70 80 90 100
pF1KA0 WRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPY
::::::::::::::::::::::::::::::
XP_005 MWLGVPSQDKMEIRSCLPKLLLAHHKTLPY
10 20 30
110 120 130 140 150 160
pF1KA0 FIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA0 SVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQS
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA0 PSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDI
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA0 RARKMASVNGSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RARKMASVNGSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLL
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA0 QKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKY
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA0 TFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFR
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA0 YNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYL
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA0 GLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDAL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA0 TVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHR
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA0 QNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFN
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA0 RITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRN
640 650 660 670 680 690
770 780 790 800 810 820
pF1KA0 LKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQESVQVSLAL
700 710 720 730 740 750
830 840 850 860 870 880
pF1KA0 FPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLAESILHEGST
760 770 780 790 800 810
890 900 910 920 930 940
pF1KA0 GCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVKAELFELLFR
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KA0 TLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLE
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KA0 TLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAA
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KA0 FLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVK
1000 1010 1020 1030 1040 1050
pF1KA0 L
:
XP_005 L
>>XP_005255255 (OMIM: 608411) PREDICTED: exportin-6 isof (951 aa)
initn: 6112 init1: 6112 opt: 6112 Z-score: 7238.6 bits: 1351.0 E(85289): 0
Smith-Waterman score: 6112; 99.8% identity (99.9% similar) in 940 aa overlap (186-1125:12-951)
160 170 180 190 200 210
pF1KA0 ELACPREDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESG
:. :::::::::::::::::::::::::::
XP_005 MVKKGMFKYSCLIRGILETVWDKHSVTAATPPPSPTSGESG
10 20 30 40
220 230 240 250 260 270
pF1KA0 DLLSNLLQSPSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLLSNLLQSPSSAKLLNQPIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIF
50 60 70 80 90 100
280 290 300 310 320 330
pF1KA0 HFARFGCDIRARKMASVNGSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HFARFGCDIRARKMASVNGSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLR
110 120 130 140 150 160
340 350 360 370 380 390
pF1KA0 MFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVV
170 180 190 200 210 220
400 410 420 430 440 450
pF1KA0 EFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLT
230 240 250 260 270 280
460 470 480 490 500 510
pF1KA0 EVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPV
290 300 310 320 330 340
520 530 540 550 560 570
pF1KA0 LQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDV
350 360 370 380 390 400
580 590 600 610 620 630
pF1KA0 FAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWL
410 420 430 440 450 460
640 650 660 670 680 690
pF1KA0 AQYCSEVHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQYCSEVHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVFLIS
470 480 490 500 510 520
700 710 720 730 740 750
pF1KA0 IPAVQKVFNRITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPAVQKVFNRITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHASLI
530 540 550 560 570 580
760 770 780 790 800 810
pF1KA0 SALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQSLQ
590 600 610 620 630 640
820 830 840 850 860 870
pF1KA0 ESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTREQLA
650 660 670 680 690 700
880 890 900 910 920 930
pF1KA0 ESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSPDVK
710 720 730 740 750 760
940 950 960 970 980 990
pF1KA0 AELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPDIHL
770 780 790 800 810 820
1000 1010 1020 1030 1040 1050
pF1KA0 FKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYNMAS
830 840 850 860 870 880
1060 1070 1080 1090 1100 1110
pF1KA0 VDFDGFFAAFLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDFDGFFAAFLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYRLCN
890 900 910 920 930 940
1120
pF1KA0 DSLPPGTVKL
::::::::::
XP_005 DSLPPGTVKL
950
>>XP_005255256 (OMIM: 608411) PREDICTED: exportin-6 isof (780 aa)
initn: 4939 init1: 4939 opt: 4939 Z-score: 5849.2 bits: 1093.6 E(85289): 0
Smith-Waterman score: 4939; 99.7% identity (99.9% similar) in 763 aa overlap (363-1125:18-780)
340 350 360 370 380 390
pF1KA0 LLRMFQQTFYLLQKITKDNNAHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIESYSQF
:. :::::::::::::::::::::::::::
XP_005 MGLLVRNRKVVNGMKGCLSCSYIEKFTDFLRLFVSVHLRRIESYSQF
10 20 30 40
400 410 420 430 440 450
pF1KA0 PVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVVEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDALVL
50 60 70 80 90 100
460 470 480 490 500 510
pF1KA0 LLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHAFSTL
110 120 130 140 150 160
520 530 540 550 560 570
pF1KA0 FPVLQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPVLQDNLEVYLGLQQFIVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGRLAEYFI
170 180 190 200 210 220
580 590 600 610 620 630
pF1KA0 GDVFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDVFAARFNDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQSLAALQAYS
230 240 250 260 270 280
640 650 660 670 680 690
pF1KA0 HWLAQYCSEVHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HWLAQYCSEVHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLVSLATTVRPVF
290 300 310 320 330 340
700 710 720 730 740 750
pF1KA0 LISIPAVQKVFNRITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISIPAVQKVFNRITDASALRLVDKAQVLVCRALSNILLLPWPNLPENEQQWPVRSINHA
350 360 370 380 390 400
760 770 780 790 800 810
pF1KA0 SLISALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLISALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENISGESTKSRQICYQ
410 420 430 440 450 460
820 830 840 850 860 870
pF1KA0 SLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVPFTEQIIQTFLNMFTRE
470 480 490 500 510 520
880 890 900 910 920 930
pF1KA0 QLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSIIALCMEQVYPIIAERPSP
530 540 550 560 570 580
940 950 960 970 980 990
pF1KA0 DVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQMENEPQFSAIMQAFGQSFLQPD
590 600 610 620 630 640
1000 1010 1020 1030 1040 1050
pF1KA0 IHLFKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHLFKQNLFYLETLNTKQKLYHKKIFRTAMLFQFVNVLLQVLVHKSHDLLQEEIGIAIYN
650 660 670 680 690 700
1060 1070 1080 1090 1100 1110
pF1KA0 MASVDFDGFFAAFLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVDFDGFFAAFLPEFLTSCDGVDANQKSVLGRNFKMDRDLPSFTQNVHRLVNDLRYYR
710 720 730 740 750 760
1120
pF1KA0 LCNDSLPPGTVKL
:::::::::::::
XP_005 LCNDSLPPGTVKL
770 780
>>XP_011544074 (OMIM: 608411) PREDICTED: exportin-6 isof (719 aa)
initn: 4664 init1: 4664 opt: 4664 Z-score: 5523.7 bits: 1033.3 E(85289): 0
Smith-Waterman score: 4664; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717)
10 20 30 40 50 60
pF1KA0 MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTLPYFIRNKLCKVIVDIGRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACPREDLSVARKEELRKLLLDQV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQPIPILDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVNGSSQNCV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQTFYLLQKITKDNNAHTVKSRL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELDESYIEKFTDFLRLFVSVHLRRIESYSQFPVVEFLTLLFKYTFHQPTHEGYFSCLDI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTLFLDYLTSKIKSRLGDKEAVLNRYEDALVLLLTEVLNRIQFRYNQAQLEELDDETLDD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQQTEWQRYLRQSLEVVAKVMELLPTHAFSTLFPVLQDNLEVYLGLQQFIVTSGSGHRLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITAENDCRRLHCSLRDLSSLLQAVGRLAEYFIGDVFAARFNDALTVVERLVKVTLYGSQI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLYNIETAVPSVLKPDLIDVHAQSLAALQAYSHWLAQYCSEVHRQNTQQFVTLISTTMDA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKAQV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITPLISTKVQDKLLLSACHLLVSLATTVRPVFLISIPAVQKVFNRITDASALRLVDKPN
670 680 690 700 710
730 740 750 760 770 780
pF1KA0 LVCRALSNILLLPWPNLPENEQQWPVRSINHASLISALSRDYRNLKPSAVAPQRKMPLDD
1125 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:29:04 2016 done: Thu Nov 3 09:29:07 2016
Total Scan time: 14.930 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]