Result of FASTA (omim) for
pF1KA0374
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0374, 538 aa
1>>>pF1KA0374 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1576+/-0.000332; mu= -3.0771+/- 0.021
mean_var=224.5152+/-45.574, 0's: 0 Z-trim(123.2): 26 B-trim: 1774 in 1/57
Lambda= 0.085596
statistics sampled from 42639 (42670) to 42639 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.5), width: 16
Scan time: 10.890
The best scores are: opt bits E(85289)
NP_001305163 (OMIM: 604942) syntaphilin isoform 1 ( 538) 3626 460.2 7e-129
NP_055538 (OMIM: 604942) syntaphilin isoform 2 [Ho ( 494) 3305 420.6 5.6e-117
XP_005260946 (OMIM: 604942) PREDICTED: syntaphilin ( 527) 3204 408.1 3.4e-113
XP_011527706 (OMIM: 604942) PREDICTED: syntaphilin ( 527) 3204 408.1 3.4e-113
XP_011527705 (OMIM: 604942) PREDICTED: syntaphilin ( 571) 3204 408.1 3.6e-113
XP_011527704 (OMIM: 604942) PREDICTED: syntaphilin ( 571) 3204 408.1 3.6e-113
NP_001317525 (OMIM: 611568) syntabulin isoform e [ ( 533) 870 119.9 2e-26
XP_016869103 (OMIM: 611568) PREDICTED: syntabulin ( 544) 870 119.9 2e-26
NP_001093219 (OMIM: 611568) syntabulin isoform d [ ( 544) 870 119.9 2e-26
XP_016869104 (OMIM: 611568) PREDICTED: syntabulin ( 544) 870 119.9 2e-26
NP_001093216 (OMIM: 611568) syntabulin isoform d [ ( 544) 870 119.9 2e-26
NP_001093225 (OMIM: 611568) syntabulin isoform d [ ( 544) 870 119.9 2e-26
NP_001093226 (OMIM: 611568) syntabulin isoform c [ ( 660) 870 119.9 2.4e-26
NP_060256 (OMIM: 611568) syntabulin isoform b [Hom ( 662) 870 119.9 2.4e-26
NP_001093221 (OMIM: 611568) syntabulin isoform b [ ( 662) 870 119.9 2.4e-26
NP_001093213 (OMIM: 611568) syntabulin isoform b [ ( 662) 870 119.9 2.4e-26
NP_001093217 (OMIM: 611568) syntabulin isoform b [ ( 662) 870 119.9 2.4e-26
NP_001093223 (OMIM: 611568) syntabulin isoform b [ ( 662) 870 119.9 2.4e-26
NP_001093214 (OMIM: 611568) syntabulin isoform a [ ( 663) 870 119.9 2.4e-26
NP_001093220 (OMIM: 611568) syntabulin isoform a [ ( 663) 870 119.9 2.4e-26
NP_001093215 (OMIM: 611568) syntabulin isoform a [ ( 663) 870 119.9 2.4e-26
NP_001093222 (OMIM: 611568) syntabulin isoform a [ ( 663) 870 119.9 2.4e-26
NP_001093218 (OMIM: 611568) syntabulin isoform a [ ( 663) 870 119.9 2.4e-26
NP_001093224 (OMIM: 611568) syntabulin isoform a [ ( 663) 870 119.9 2.4e-26
XP_011515456 (OMIM: 611568) PREDICTED: syntabulin ( 496) 867 119.5 2.4e-26
XP_005251057 (OMIM: 611568) PREDICTED: syntabulin ( 500) 867 119.5 2.4e-26
>>NP_001305163 (OMIM: 604942) syntaphilin isoform 1 [Hom (538 aa)
initn: 3626 init1: 3626 opt: 3626 Z-score: 2434.8 bits: 460.2 E(85289): 7e-129
Smith-Waterman score: 3626; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KA0 MPGSGPSERMTWPGPALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGSGPSERMTWPGPALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 TPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLLCGMEAGVQASCMQERAIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLLCGMEAGVQASCMQERAIQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSGPRDPNSAVVVTVGDELEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSGPRDPNSAVVVTVGDELEAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 EPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPA
430 440 450 460 470 480
490 500 510 520 530
pF1KA0 VPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
490 500 510 520 530
>>NP_055538 (OMIM: 604942) syntaphilin isoform 2 [Homo s (494 aa)
initn: 3305 init1: 3305 opt: 3305 Z-score: 2221.1 bits: 420.6 E(85289): 5.6e-117
Smith-Waterman score: 3305; 100.0% identity (100.0% similar) in 494 aa overlap (45-538:1-494)
20 30 40 50 60 70
pF1KA0 PALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSRRRTSPPVSVRDAYG
::::::::::::::::::::::::::::::
NP_055 MAMSLPGSRRTSAGSRRRTSPPVSVRDAYG
10 20 30
80 90 100 110 120 130
pF1KA0 TSSLSSSSNSGSYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TSSLSSSSNSGSYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA0 ARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVID
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA0 TVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLT
160 170 180 190 200 210
260 270 280 290 300 310
pF1KA0 RSSTYTKLSDPAVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RSSTYTKLSDPAVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDC
220 230 240 250 260 270
320 330 340 350 360 370
pF1KA0 GTEETSLHSSFGLGPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTEETSLHSSFGLGPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILE
280 290 300 310 320 330
380 390 400 410 420 430
pF1KA0 KVTQAQVCGTDPESGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVTQAQVCGTDPESGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGA
340 350 360 370 380 390
440 450 460 470 480 490
pF1KA0 NPNPGQSVSVVCPMEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NPNPGQSVSVVCPMEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQ
400 410 420 430 440 450
500 510 520 530
pF1KA0 GQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
::::::::::::::::::::::::::::::::::::::::::::
NP_055 GQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
460 470 480 490
>>XP_005260946 (OMIM: 604942) PREDICTED: syntaphilin iso (527 aa)
initn: 3291 init1: 3204 opt: 3204 Z-score: 2153.3 bits: 408.1 E(85289): 3.4e-113
Smith-Waterman score: 3229; 93.7% identity (93.7% similar) in 527 aa overlap (45-538:1-527)
20 30 40 50 60
pF1KA0 PALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR--------------
::::::::::::::::
XP_005 MAMSLPGSRRTSAGSRSGGTLGRSGLAVFA
10 20 30
70 80 90 100
pF1KA0 -------------------RRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMK
:::::::::::::::::::::::::::::::::::::::::
XP_005 QCPQLPASQNEHLPLLPASRRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMK
40 50 60 70 80 90
110 120 130 140 150 160
pF1KA0 YTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRM
100 110 120 130 140 150
170 180 190 200 210 220
pF1KA0 QEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL
160 170 180 190 200 210
230 240 250 260 270 280
pF1KA0 ETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KA0 EDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLL
280 290 300 310 320 330
350 360 370 380 390 400
pF1KA0 CGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSG
340 350 360 370 380 390
410 420 430 440 450 460
pF1KA0 PRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEP
400 410 420 430 440 450
470 480 490 500 510 520
pF1KA0 KSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISC
460 470 480 490 500 510
530
pF1KA0 RSLSQPSPSPAGGGSQL
:::::::::::::::::
XP_005 RSLSQPSPSPAGGGSQL
520
>>XP_011527706 (OMIM: 604942) PREDICTED: syntaphilin iso (527 aa)
initn: 3291 init1: 3204 opt: 3204 Z-score: 2153.3 bits: 408.1 E(85289): 3.4e-113
Smith-Waterman score: 3229; 93.7% identity (93.7% similar) in 527 aa overlap (45-538:1-527)
20 30 40 50 60
pF1KA0 PALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR--------------
::::::::::::::::
XP_011 MAMSLPGSRRTSAGSRSGGTLGRSGLAVFA
10 20 30
70 80 90 100
pF1KA0 -------------------RRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMK
:::::::::::::::::::::::::::::::::::::::::
XP_011 QCPQLPASQNEHLPLLPASRRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMK
40 50 60 70 80 90
110 120 130 140 150 160
pF1KA0 YTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRM
100 110 120 130 140 150
170 180 190 200 210 220
pF1KA0 QEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL
160 170 180 190 200 210
230 240 250 260 270 280
pF1KA0 ETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KA0 EDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLL
280 290 300 310 320 330
350 360 370 380 390 400
pF1KA0 CGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSG
340 350 360 370 380 390
410 420 430 440 450 460
pF1KA0 PRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEP
400 410 420 430 440 450
470 480 490 500 510 520
pF1KA0 KSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISC
460 470 480 490 500 510
530
pF1KA0 RSLSQPSPSPAGGGSQL
:::::::::::::::::
XP_011 RSLSQPSPSPAGGGSQL
520
>>XP_011527705 (OMIM: 604942) PREDICTED: syntaphilin iso (571 aa)
initn: 3612 init1: 3204 opt: 3204 Z-score: 2152.7 bits: 408.1 E(85289): 3.6e-113
Smith-Waterman score: 3543; 94.2% identity (94.2% similar) in 570 aa overlap (2-538:2-571)
10 20 30 40 50 60
pF1KA0 MPGSGPSERMTWPGPALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGSGPSERMTWPGPALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR
10 20 30 40 50 60
70 80
pF1KA0 ---------------------------------RRTSPPVSVRDAYGTSSLSSSSNSGSY
:::::::::::::::::::::::::::
XP_011 SGGTLGRSGLAVFAQCPQLPASQNEHLPLLPASRRTSPPVSVRDAYGTSSLSSSSNSGSY
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 KGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDR
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 DTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 QKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAV
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 CGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 GPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 SGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCP
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRG
490 500 510 520 530 540
510 520 530
pF1KA0 CCTVALHSIRRISCRSLSQPSPSPAGGGSQL
:::::::::::::::::::::::::::::::
XP_011 CCTVALHSIRRISCRSLSQPSPSPAGGGSQL
550 560 570
>>XP_011527704 (OMIM: 604942) PREDICTED: syntaphilin iso (571 aa)
initn: 3612 init1: 3204 opt: 3204 Z-score: 2152.7 bits: 408.1 E(85289): 3.6e-113
Smith-Waterman score: 3543; 94.2% identity (94.2% similar) in 570 aa overlap (2-538:2-571)
10 20 30 40 50 60
pF1KA0 MPGSGPSERMTWPGPALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGSGPSERMTWPGPALSAGPPTRPLSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSR
10 20 30 40 50 60
70 80
pF1KA0 ---------------------------------RRTSPPVSVRDAYGTSSLSSSSNSGSY
:::::::::::::::::::::::::::
XP_011 SGGTLGRSGLAVFAQCPQLPASQNEHLPLLPASRRTSPPVSVRDAYGTSSLSSSSNSGSY
70 80 90 100 110 120
90 100 110 120 130 140
pF1KA0 KGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDR
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 DTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGL
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 QKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAV
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 CGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 GPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPE
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 SGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCP
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 MEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRG
490 500 510 520 530 540
510 520 530
pF1KA0 CCTVALHSIRRISCRSLSQPSPSPAGGGSQL
:::::::::::::::::::::::::::::::
XP_011 CCTVALHSIRRISCRSLSQPSPSPAGGGSQL
550 560 570
>>NP_001317525 (OMIM: 611568) syntabulin isoform e [Homo (533 aa)
initn: 1181 init1: 808 opt: 870 Z-score: 595.5 bits: 119.9 E(85289): 2e-26
Smith-Waterman score: 1171; 41.8% identity (64.8% similar) in 545 aa overlap (4-522:28-530)
10 20
pF1KA0 MPGSGPSERMTWPGPALSA-----GPPTRP---LSS
:.: .:. : :. :: : :
NP_001 MFAMKVYGAYLLSSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGASSH
10 20 30 40 50 60
30 40 50 60 70 80
pF1KA0 APGIPPIPPLTRTHSLMAMSLPGSRRTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSGSYK
:: : : : ..:..: : . :: :... .:. :: :::::::::
NP_001 KPGSSPSSP--REKDLLSML----------CRNQLSP-VNIHPSYAPSS-PSSSNSGSYK
70 80 90 100
90 100 110 120 130 140
pF1KA0 GSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRD
::: :: ::: .: :..:::..::.::::::::::::: .::::..::... ::..:.
NP_001 GSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLHERE
110 120 130 140 150 160
150 160 170 180 190 200
pF1KA0 TEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQ
.:: .::.::.::.:::::::::::::::::::::::::::::::.:....: :::::.:
NP_001 SEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDKGIQ
170 180 190 200 210 220
210 220 230 240 250 260
pF1KA0 KYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAVC
::::::::::::::.::.:::.:..: ... . :: .::: . ..:
NP_001 KYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADGLSL
230 240 250 260 270 280
270 280 290 300 310 320
pF1KA0 GDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGLG
.. :. ::: . ..:. . :: .. . .. .. : : .::.
NP_001 EEQVTGE--------GADRELLVGDSIANSTDLFDEI-VTATTTESGDLEL-VHST----
290 300 310 320 330
330 340 350 360 370 380
pF1KA0 PRFPASNTYEKL--LCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQA--QVCGT
:..:. : : . :.: : : . :::.::: : :.: .. ....: : . : .
NP_001 ---PGANVLELLPIVMGQEEG---SVVVERAVQTDVVPYSPAISELIQSVLQKLQDPCPS
340 350 360 370 380
390 400 410 420 430
pF1KA0 --------DPESGDRCPE-LDAHPSG--PRDPNSAVVVTVGDELEAPEPITRGPTPQRPG
.:.: . :: :.: ::.::::.... .:.: . . .
NP_001 SLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLS---PVETP----YANVDAEVH
390 400 410 420 430
440 450 460 470 480 490
pF1KA0 ANPNPGQSVSVVCPMEEEEEAAVAEKEP---KSYWSRHYIVDLLAVVVPAVPTVAWLCRS
:: . ..: .::. .... . ..::: ..::::::..:.:::: : .
NP_001 ANRLMRELDFAAC-VEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWAFST
440 450 460 470 480 490
500 510 520 530
pF1KA0 QRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
:: .:.:::..::::::.:::::.:: . :
NP_001 QRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
500 510 520 530
>>XP_016869103 (OMIM: 611568) PREDICTED: syntabulin isof (544 aa)
initn: 1157 init1: 808 opt: 870 Z-score: 595.4 bits: 119.9 E(85289): 2e-26
Smith-Waterman score: 1171; 41.8% identity (64.8% similar) in 545 aa overlap (4-522:39-541)
10 20
pF1KA0 MPGSGPSERMTWPGPALSA-----GPPTRP---
:.: .:. : :. :: :
XP_016 SSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGA
10 20 30 40 50 60
30 40 50 60 70 80
pF1KA0 LSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSG
: :: : : : ..:..: : . :: :... .:. :: ::::::
XP_016 SSHKPGSSPSSP--REKDLLSML----------CRNQLSP-VNIHPSYAPSS-PSSSNSG
70 80 90 100 110
90 100 110 120 130 140
pF1KA0 SYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQ
:::::: :: ::: .: :..:::..::.::::::::::::: .::::..::... ::.
XP_016 SYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLH
120 130 140 150 160 170
150 160 170 180 190 200
pF1KA0 DRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDK
.:..:: .::.::.::.:::::::::::::::::::::::::::::::.:....: ::::
XP_016 ERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDK
180 190 200 210 220 230
210 220 230 240 250 260
pF1KA0 GLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDP
:.:::::::::::::::.::.:::.:..: ... . :: .::: . ..:
XP_016 GIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KA0 AVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSF
.. :. ::: . ..:. . :: .. . .. .. : : .::.
XP_016 LSLEEQVTGE--------GADRELLVGDSIANSTDLFDEI-VTATTTESGDLEL-VHST-
300 310 320 330 340
330 340 350 360 370 380
pF1KA0 GLGPRFPASNTYEKL--LCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQA--QV
:..:. : : . :.: : : . :::.::: : :.: .. ....: : .
XP_016 ------PGANVLELLPIVMGQEEG---SVVVERAVQTDVVPYSPAISELIQSVLQKLQDP
350 360 370 380 390
390 400 410 420 430
pF1KA0 CGT--------DPESGDRCPE-LDAHPSG--PRDPNSAVVVTVGDELEAPEPITRGPTPQ
: . .:.: . :: :.: ::.::::.... .:.: . .
XP_016 CPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLS---PVETP----YANVDA
400 410 420 430 440
440 450 460 470 480
pF1KA0 RPGANPNPGQSVSVVCPMEEEEEAAVAEKEP---KSYWSRHYIVDLLAVVVPAVPTVAWL
. :: . ..: .::. .... . ..::: ..::::::..:.:::: :
XP_016 EVHANRLMRELDFAAC-VEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWA
450 460 470 480 490 500
490 500 510 520 530
pF1KA0 CRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
.:: .:.:::..::::::.:::::.:: . :
XP_016 FSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
510 520 530 540
>>NP_001093219 (OMIM: 611568) syntabulin isoform d [Homo (544 aa)
initn: 1157 init1: 808 opt: 870 Z-score: 595.4 bits: 119.9 E(85289): 2e-26
Smith-Waterman score: 1171; 41.8% identity (64.8% similar) in 545 aa overlap (4-522:39-541)
10 20
pF1KA0 MPGSGPSERMTWPGPALSA-----GPPTRP---
:.: .:. : :. :: :
NP_001 SSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGA
10 20 30 40 50 60
30 40 50 60 70 80
pF1KA0 LSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSG
: :: : : : ..:..: : . :: :... .:. :: ::::::
NP_001 SSHKPGSSPSSP--REKDLLSML----------CRNQLSP-VNIHPSYAPSS-PSSSNSG
70 80 90 100 110
90 100 110 120 130 140
pF1KA0 SYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQ
:::::: :: ::: .: :..:::..::.::::::::::::: .::::..::... ::.
NP_001 SYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLH
120 130 140 150 160 170
150 160 170 180 190 200
pF1KA0 DRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDK
.:..:: .::.::.::.:::::::::::::::::::::::::::::::.:....: ::::
NP_001 ERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDK
180 190 200 210 220 230
210 220 230 240 250 260
pF1KA0 GLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDP
:.:::::::::::::::.::.:::.:..: ... . :: .::: . ..:
NP_001 GIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KA0 AVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSF
.. :. ::: . ..:. . :: .. . .. .. : : .::.
NP_001 LSLEEQVTGE--------GADRELLVGDSIANSTDLFDEI-VTATTTESGDLEL-VHST-
300 310 320 330 340
330 340 350 360 370 380
pF1KA0 GLGPRFPASNTYEKL--LCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQA--QV
:..:. : : . :.: : : . :::.::: : :.: .. ....: : .
NP_001 ------PGANVLELLPIVMGQEEG---SVVVERAVQTDVVPYSPAISELIQSVLQKLQDP
350 360 370 380 390
390 400 410 420 430
pF1KA0 CGT--------DPESGDRCPE-LDAHPSG--PRDPNSAVVVTVGDELEAPEPITRGPTPQ
: . .:.: . :: :.: ::.::::.... .:.: . .
NP_001 CPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLS---PVETP----YANVDA
400 410 420 430 440
440 450 460 470 480
pF1KA0 RPGANPNPGQSVSVVCPMEEEEEAAVAEKEP---KSYWSRHYIVDLLAVVVPAVPTVAWL
. :: . ..: .::. .... . ..::: ..::::::..:.:::: :
NP_001 EVHANRLMRELDFAAC-VEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWA
450 460 470 480 490 500
490 500 510 520 530
pF1KA0 CRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
.:: .:.:::..::::::.:::::.:: . :
NP_001 FSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
510 520 530 540
>>XP_016869104 (OMIM: 611568) PREDICTED: syntabulin isof (544 aa)
initn: 1157 init1: 808 opt: 870 Z-score: 595.4 bits: 119.9 E(85289): 2e-26
Smith-Waterman score: 1171; 41.8% identity (64.8% similar) in 545 aa overlap (4-522:39-541)
10 20
pF1KA0 MPGSGPSERMTWPGPALSA-----GPPTRP---
:.: .:. : :. :: :
XP_016 SSRYKKESKSGLVKPGSEADFSSSSSTGSISAPEVHMSTAGSKRSSSSRNRGPHGRSNGA
10 20 30 40 50 60
30 40 50 60 70 80
pF1KA0 LSSAPGIPPIPPLTRTHSLMAMSLPGSRRTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSG
: :: : : : ..:..: : . :: :... .:. :: ::::::
XP_016 SSHKPGSSPSSP--REKDLLSML----------CRNQLSP-VNIHPSYAPSS-PSSSNSG
70 80 90 100 110
90 100 110 120 130 140
pF1KA0 SYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQ
:::::: :: ::: .: :..:::..::.::::::::::::: .::::..::... ::.
XP_016 SYKGSDCSPIMRRSGRYMSCGENHGVRPPNPEQYLTPLQQKEVTVRHLKTKLKESERRLH
120 130 140 150 160 170
150 160 170 180 190 200
pF1KA0 DRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDK
.:..:: .::.::.::.:::::::::::::::::::::::::::::::.:....: ::::
XP_016 ERESEIVELKSQLARMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMRSSLADKDK
180 190 200 210 220 230
210 220 230 240 250 260
pF1KA0 GLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDP
:.:::::::::::::::.::.:::.:..: ... . :: .::: . ..:
XP_016 GIQKYFVDINIQNKKLESLLQSMEMAHSGSLRDELCLDFPCDSPEKSLTLNPPLDTMADG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KA0 AVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSF
.. :. ::: . ..:. . :: .. . .. .. : : .::.
XP_016 LSLEEQVTGE--------GADRELLVGDSIANSTDLFDEI-VTATTTESGDLEL-VHST-
300 310 320 330 340
330 340 350 360 370 380
pF1KA0 GLGPRFPASNTYEKL--LCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQA--QV
:..:. : : . :.: : : . :::.::: : :.: .. ....: : .
XP_016 ------PGANVLELLPIVMGQEEG---SVVVERAVQTDVVPYSPAISELIQSVLQKLQDP
350 360 370 380 390
390 400 410 420 430
pF1KA0 CGT--------DPESGDRCPE-LDAHPSG--PRDPNSAVVVTVGDELEAPEPITRGPTPQ
: . .:.: . :: :.: ::.::::.... .:.: . .
XP_016 CPSSLASPDESEPDSMESFPESLSALVVDLTPRNPNSAILLS---PVETP----YANVDA
400 410 420 430 440
440 450 460 470 480
pF1KA0 RPGANPNPGQSVSVVCPMEEEEEAAVAEKEP---KSYWSRHYIVDLLAVVVPAVPTVAWL
. :: . ..: .::. .... . ..::: ..::::::..:.:::: :
XP_016 EVHANRLMRELDFAAC-VEERLDGVIPLARGGVVRQYWSSSFLVDLLAVAAPVVPTVLWA
450 460 470 480 490 500
490 500 510 520 530
pF1KA0 CRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
.:: .:.:::..::::::.:::::.:: . :
XP_016 FSTQRGGTDPVYNIGALLRGCCVVALHSLRRTAFRIKT
510 520 530 540
538 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:38:50 2016 done: Fri Nov 4 00:38:52 2016
Total Scan time: 10.890 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]