FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0377, 1406 aa 1>>>pF1KA0377 1406 - 1406 aa - 1406 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3582+/-0.000442; mu= 10.1541+/- 0.028 mean_var=212.3092+/-43.414, 0's: 0 Z-trim(117.4): 116 B-trim: 822 in 1/57 Lambda= 0.088022 statistics sampled from 29164 (29303) to 29164 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.344), width: 16 Scan time: 16.750 The best scores are: opt bits E(85289) NP_001177143 (OMIM: 610979) inositol hexakisphosph (1406) 9444 1213.6 0 XP_016878238 (OMIM: 610979) PREDICTED: inositol he (1408) 8553 1100.4 0 XP_016878237 (OMIM: 610979) PREDICTED: inositol he (1408) 8553 1100.4 0 NP_001124331 (OMIM: 610979) inositol hexakisphosph (1408) 8553 1100.4 0 XP_016878239 (OMIM: 610979) PREDICTED: inositol he (1408) 8553 1100.4 0 XP_016878240 (OMIM: 610979) PREDICTED: inositol he (1408) 8553 1100.4 0 XP_005254861 (OMIM: 610979) PREDICTED: inositol he (1408) 8553 1100.4 0 NP_055474 (OMIM: 610979) inositol hexakisphosphate (1408) 8553 1100.4 0 XP_016878241 (OMIM: 610979) PREDICTED: inositol he (1400) 8464 1089.1 0 XP_016878242 (OMIM: 610979) PREDICTED: inositol he (1400) 8464 1089.1 0 XP_016878244 (OMIM: 610979) PREDICTED: inositol he (1366) 7609 980.6 0 XP_016878243 (OMIM: 610979) PREDICTED: inositol he (1366) 7609 980.6 0 XP_016878245 (OMIM: 610979) PREDICTED: inositol he (1366) 7609 980.6 0 XP_006720849 (OMIM: 610979) PREDICTED: inositol he (1366) 7609 980.6 0 XP_016878246 (OMIM: 610979) PREDICTED: inositol he (1366) 7609 980.6 0 XP_016878235 (OMIM: 610979) PREDICTED: inositol he (1421) 7104 916.4 0 XP_011520561 (OMIM: 610979) PREDICTED: inositol he (1421) 7104 916.4 0 XP_016878234 (OMIM: 610979) PREDICTED: inositol he (1421) 7104 916.4 0 XP_016878232 (OMIM: 610979) PREDICTED: inositol he (1429) 7070 912.1 0 XP_016878229 (OMIM: 610979) PREDICTED: inositol he (1429) 7070 912.1 0 XP_016878230 (OMIM: 610979) PREDICTED: inositol he (1429) 7070 912.1 0 XP_016878233 (OMIM: 610979) PREDICTED: inositol he (1429) 7070 912.1 0 XP_005254860 (OMIM: 610979) PREDICTED: inositol he (1429) 7070 912.1 0 XP_016878231 (OMIM: 610979) PREDICTED: inositol he (1429) 7070 912.1 0 NP_001124330 (OMIM: 610979) inositol hexakisphosph (1433) 7049 909.5 0 XP_016878236 (OMIM: 610979) PREDICTED: inositol he (1416) 6976 900.2 0 XP_016878247 (OMIM: 610979) PREDICTED: inositol he (1153) 6811 879.1 0 XP_016878228 (OMIM: 610979) PREDICTED: inositol he (1458) 6717 867.3 0 XP_011520551 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_011520552 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_016878225 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_011520556 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_016878226 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_011520554 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_016878224 (OMIM: 610979) PREDICTED: inositol he (1479) 6658 859.8 0 XP_016878227 (OMIM: 610979) PREDICTED: inositol he (1471) 6604 853.0 0 XP_016878248 (OMIM: 610979) PREDICTED: inositol he ( 817) 5466 708.2 6.3e-203 NP_001332804 (OMIM: 611648) inositol hexakisphosph (1124) 5153 668.6 7.3e-191 NP_001332806 (OMIM: 611648) inositol hexakisphosph (1123) 5133 666.1 4.2e-190 NP_001332803 (OMIM: 611648) inositol hexakisphosph (1164) 4988 647.7 1.5e-184 XP_016864763 (OMIM: 611648) PREDICTED: inositol he (1145) 4986 647.4 1.8e-184 NP_001332800 (OMIM: 611648) inositol hexakisphosph (1185) 4975 646.0 4.8e-184 XP_016864762 (OMIM: 611648) PREDICTED: inositol he (1163) 4968 645.1 8.8e-184 NP_001332805 (OMIM: 611648) inositol hexakisphosph (1182) 4966 644.9 1.1e-183 NP_056031 (OMIM: 611648) inositol hexakisphosphate (1222) 4963 644.5 1.4e-183 NP_001263206 (OMIM: 611648) inositol hexakisphosph (1243) 4963 644.5 1.4e-183 NP_001332807 (OMIM: 611648) inositol hexakisphosph (1181) 4946 642.3 6.2e-183 NP_001332802 (OMIM: 611648) inositol hexakisphosph (1242) 4943 642.0 8.4e-183 XP_011520560 (OMIM: 610979) PREDICTED: inositol he (1224) 4916 638.5 8.9e-182 XP_011541592 (OMIM: 611648) PREDICTED: inositol he (1038) 4527 589.1 5.9e-167 >>NP_001177143 (OMIM: 610979) inositol hexakisphosphate (1406 aa) initn: 9444 init1: 9444 opt: 9444 Z-score: 6491.2 bits: 1213.6 E(85289): 0 Smith-Waterman score: 9444; 100.0% identity (100.0% similar) in 1406 aa overlap (1-1406:1-1406) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGFEGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGFEGC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 SMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 RTLHSPPLQLQQRSEKPPWLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLHSPPLQLQQRSEKPPWLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPD 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 SSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGPSSTVSSAGPSSPTTVDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 EGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGEQELFEPNQSPQVPPMETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 QCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 KLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLVHKFHVGVGSLVQETLVEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGI 1330 1340 1350 1360 1370 1380 1390 1400 pF1KA0 PEIDKPSQEFPEEIDLQAQEVPEEIN :::::::::::::::::::::::::: NP_001 PEIDKPSQEFPEEIDLQAQEVPEEIN 1390 1400 >>XP_016878238 (OMIM: 610979) PREDICTED: inositol hexaki (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_016 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_016 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: XP_016 QEVPEEIN >>XP_016878237 (OMIM: 610979) PREDICTED: inositol hexaki (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_016 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_016 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: XP_016 QEVPEEIN >>NP_001124331 (OMIM: 610979) inositol hexakisphosphate (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: NP_001 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: NP_001 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: NP_001 QEVPEEIN >>XP_016878239 (OMIM: 610979) PREDICTED: inositol hexaki (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_016 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_016 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: XP_016 QEVPEEIN >>XP_016878240 (OMIM: 610979) PREDICTED: inositol hexaki (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_016 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_016 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: XP_016 QEVPEEIN >>XP_005254861 (OMIM: 610979) PREDICTED: inositol hexaki (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_005 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_005 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: XP_005 QEVPEEIN >>NP_055474 (OMIM: 610979) inositol hexakisphosphate and (1408 aa) initn: 8593 init1: 6805 opt: 8553 Z-score: 5879.7 bits: 1100.4 E(85289): 0 Smith-Waterman score: 8993; 94.3% identity (94.3% similar) in 1448 aa overlap (1-1406:1-1408) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 970 980 990 1000 1010 1020 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: NP_055 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: NP_055 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1150 1160 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1170 1180 1190 1200 1210 1220 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1230 1240 1250 1260 1270 1280 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1290 1300 1310 1320 1330 1340 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1350 1360 1370 1380 1390 1400 1400 pF1KA0 QEVPEEIN :::::::: NP_055 QEVPEEIN >>XP_016878241 (OMIM: 610979) PREDICTED: inositol hexaki (1400 aa) initn: 8526 init1: 5413 opt: 8464 Z-score: 5818.7 bits: 1089.1 E(85289): 0 Smith-Waterman score: 8914; 93.7% identity (93.7% similar) in 1448 aa overlap (1-1406:1-1400) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH ::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 EEKLEIAVGFCLPLLRKILLDLQRTHEDE--------YSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 900 910 920 930 940 950 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 960 970 980 990 1000 1010 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_016 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1020 1030 1040 1050 1060 1070 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1080 1090 1100 1110 1120 1130 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_016 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1140 1150 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1340 1350 1360 1370 1380 1390 1400 pF1KA0 QEVPEEIN :::::::: XP_016 QEVPEEIN 1400 >>XP_016878242 (OMIM: 610979) PREDICTED: inositol hexaki (1400 aa) initn: 8526 init1: 5413 opt: 8464 Z-score: 5818.7 bits: 1089.1 E(85289): 0 Smith-Waterman score: 8914; 93.7% identity (93.7% similar) in 1448 aa overlap (1-1406:1-1400) 10 20 30 40 50 60 pF1KA0 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWSLTASEGESTTAHFFLGAGDEGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGIC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPARPEECNLIEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFSGINRKVQLTYYPHGVKASNEGQDPQRETLAPSLLLVLKWGGELTPAGRVQAEELGR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 EEKLEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESH ::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 EEKLEIAVGFCLPLLRKILLDLQRTHEDE--------YSRGVLSPGRHVRTRLYFTSESH 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFH 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPDRALQTS 900 910 920 930 940 950 970 980 990 1000 1010 pF1KA0 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCT 960 970 980 990 1000 1010 1020 1030 pF1KA0 --------------------------------------FEGCSMVPTIYPLETLHNALSL :::::::::::::::::::::: XP_016 GLFSTTVLGGSSSAPNLQDYARSHGKKLPPASLKHRDGFEGCSMVPTIYPLETLHNALSL 1020 1030 1040 1050 1060 1070 1040 1050 1060 1070 1080 1090 pF1KA0 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQVSEFLSRVCQRHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHSPPLQLQQRSEKPP 1080 1090 1100 1110 1120 1130 1100 1110 1120 1130 1140 1150 pF1KA0 WLETRFCHVGQAGLELLTSSDLPASASQSAGITGVSHRTQPDSSGPSSTVSSAGPSSPTT : :::::::::::::::::: XP_016 WY----------------------------------------SSGPSSTVSSAGPSSPTT 1140 1150 1160 1170 1180 1190 1200 1210 pF1KA0 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGNSQFGFSDQPSLNSHVAEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPM 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 pF1KA0 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQEVPH 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 pF1KA0 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETL 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 pF1KA0 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEVGSPAEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPEEIDLQA 1340 1350 1360 1370 1380 1390 1400 pF1KA0 QEVPEEIN :::::::: XP_016 QEVPEEIN 1400 1406 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:45:37 2016 done: Wed Nov 2 18:45:40 2016 Total Scan time: 16.750 Total Display time: 0.680 Function used was FASTA [36.3.4 Apr, 2011]