Result of FASTA (omim) for
pF1KA0381
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0381, 1068 aa
1>>>pF1KA0381 1068 - 1068 aa - 1068 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.8022+/-0.000498; mu= -8.6145+/- 0.031
mean_var=578.0513+/-119.011, 0's: 0 Z-trim(122.3): 121 B-trim: 0 in 0/59
Lambda= 0.053345
statistics sampled from 40175 (40300) to 40175 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.473), width: 16
Scan time: 12.920
The best scores are: opt bits E(85289)
NP_001188356 (OMIM: 606627) disheveled-associated (1068) 7095 561.9 7.1e-159
XP_006715103 (OMIM: 606627) PREDICTED: disheveled- (1167) 7095 561.9 7.5e-159
NP_056160 (OMIM: 606627) disheveled-associated act (1067) 7077 560.5 1.9e-158
NP_001257449 (OMIM: 606626) disheveled-associated (1068) 4887 391.9 1e-107
XP_006715106 (OMIM: 606627) PREDICTED: disheveled- (1077) 4496 361.8 1.2e-98
XP_006715105 (OMIM: 606627) PREDICTED: disheveled- (1077) 4496 361.8 1.2e-98
XP_006715109 (OMIM: 606627) PREDICTED: disheveled- (1077) 4496 361.8 1.2e-98
XP_006715108 (OMIM: 606627) PREDICTED: disheveled- (1077) 4496 361.8 1.2e-98
XP_016866119 (OMIM: 606627) PREDICTED: disheveled- (1100) 4496 361.9 1.2e-98
XP_006715102 (OMIM: 606627) PREDICTED: disheveled- (1176) 4496 361.9 1.2e-98
NP_055807 (OMIM: 606626) disheveled-associated act (1078) 3284 268.6 1.4e-70
XP_005267488 (OMIM: 606626) PREDICTED: disheveled- (1078) 3284 268.6 1.4e-70
XP_005267487 (OMIM: 606626) PREDICTED: disheveled- (1078) 3284 268.6 1.4e-70
NP_112194 (OMIM: 609129,614567) protein diaphanous ( 849) 991 92.0 1.6e-17
XP_006719939 (OMIM: 609129,614567) PREDICTED: prot ( 930) 991 92.0 1.7e-17
NP_001245298 (OMIM: 609129,614567) protein diaphan (1112) 991 92.1 1.9e-17
NP_001245297 (OMIM: 609129,614567) protein diaphan (1123) 991 92.1 1.9e-17
XP_011533560 (OMIM: 609129,614567) PREDICTED: prot (1136) 991 92.1 1.9e-17
NP_001245296 (OMIM: 609129,614567) protein diaphan (1147) 991 92.1 1.9e-17
NP_001245295 (OMIM: 609129,614567) protein diaphan (1182) 991 92.1 2e-17
NP_001035982 (OMIM: 609129,614567) protein diaphan (1193) 991 92.1 2e-17
NP_006720 (OMIM: 300108,300511) protein diaphanous (1101) 981 91.3 3.2e-17
NP_009293 (OMIM: 300108,300511) protein diaphanous (1096) 973 90.7 4.9e-17
XP_011508837 (OMIM: 616285) PREDICTED: formin-like (1048) 900 85.1 2.3e-15
NP_443137 (OMIM: 616285) formin-like protein 2 [Ho (1092) 882 83.7 6.3e-15
XP_011537275 (OMIM: 616288) PREDICTED: formin-like ( 925) 876 83.2 7.7e-15
XP_011537274 (OMIM: 616288) PREDICTED: formin-like ( 996) 876 83.2 8.1e-15
XP_011537273 (OMIM: 616288) PREDICTED: formin-like (1000) 876 83.2 8.1e-15
XP_005246322 (OMIM: 616285) PREDICTED: formin-like (1084) 877 83.3 8.1e-15
XP_011537276 (OMIM: 616288) PREDICTED: formin-like (1003) 876 83.2 8.1e-15
XP_005246320 (OMIM: 616285) PREDICTED: formin-like (1087) 877 83.3 8.1e-15
XP_005269275 (OMIM: 616288) PREDICTED: formin-like (1028) 876 83.2 8.3e-15
XP_011537272 (OMIM: 616288) PREDICTED: formin-like (1046) 876 83.2 8.4e-15
XP_011537270 (OMIM: 616288) PREDICTED: formin-like (1047) 876 83.2 8.4e-15
NP_944489 (OMIM: 616288) formin-like protein 3 iso ( 976) 868 82.6 1.2e-14
NP_783863 (OMIM: 616288) formin-like protein 3 iso (1027) 868 82.6 1.3e-14
XP_011537271 (OMIM: 616288) PREDICTED: formin-like (1046) 868 82.6 1.3e-14
XP_011508838 (OMIM: 616285) PREDICTED: formin-like ( 860) 850 81.1 2.9e-14
XP_011508832 (OMIM: 616285) PREDICTED: formin-like (1099) 850 81.3 3.5e-14
XP_011508835 (OMIM: 616285) PREDICTED: formin-like (1091) 845 80.9 4.5e-14
XP_011508833 (OMIM: 616285) PREDICTED: formin-like (1094) 845 80.9 4.5e-14
XP_011508834 (OMIM: 616285) PREDICTED: formin-like (1093) 838 80.3 6.5e-14
XP_006722132 (OMIM: 604656) PREDICTED: formin-like (1076) 789 76.6 8.8e-13
NP_005883 (OMIM: 604656) formin-like protein 1 [Ho (1100) 788 76.5 9.5e-13
XP_006722133 (OMIM: 604656) PREDICTED: formin-like (1104) 788 76.5 9.5e-13
XP_011523484 (OMIM: 604656) PREDICTED: formin-like (1106) 788 76.5 9.5e-13
XP_006722129 (OMIM: 604656) PREDICTED: formin-like (1110) 788 76.5 9.5e-13
XP_011523482 (OMIM: 604656) PREDICTED: formin-like (1133) 788 76.5 9.7e-13
XP_006722128 (OMIM: 604656) PREDICTED: formin-like (1148) 788 76.5 9.7e-13
XP_006722127 (OMIM: 604656) PREDICTED: formin-like (1154) 788 76.5 9.8e-13
>>NP_001188356 (OMIM: 606627) disheveled-associated acti (1068 aa)
initn: 7095 init1: 7095 opt: 7095 Z-score: 2973.3 bits: 561.9 E(85289): 7.1e-159
Smith-Waterman score: 7095; 100.0% identity (100.0% similar) in 1068 aa overlap (1-1068:1-1068)
10 20 30 40 50 60
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQKELGSTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQKELGSTEDI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 YLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 AILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNIS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 FDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEG
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KA0 GEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
1030 1040 1050 1060
>>XP_006715103 (OMIM: 606627) PREDICTED: disheveled-asso (1167 aa)
initn: 7095 init1: 7095 opt: 7095 Z-score: 2972.8 bits: 561.9 E(85289): 7.5e-159
Smith-Waterman score: 7095; 100.0% identity (100.0% similar) in 1068 aa overlap (1-1068:100-1167)
10 20 30
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDN
::::::::::::::::::::::::::::::
XP_006 CPRPISCGMDTDHNEDLGHLSADAPWPAVTMAPRKRSHHGLGFLCCFGGSDIPEINLRDN
70 80 90 100 110 120
40 50 60 70 80 90
pF1KA0 HPLQFMEFSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HPLQFMEFSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQED
130 140 150 160 170 180
100 110 120 130 140 150
pF1KA0 PNKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIE
190 200 210 220 230 240
160 170 180 190 200 210
pF1KA0 LEGLTCLLNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEGLTCLLNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRT
250 260 270 280 290 300
220 230 240 250 260 270
pF1KA0 ENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDE
310 320 330 340 350 360
280 290 300 310 320 330
pF1KA0 VNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDF
370 380 390 400 410 420
340 350 360 370 380 390
pF1KA0 FEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKR
430 440 450 460 470 480
400 410 420 430 440 450
pF1KA0 NGGYFQQWQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGYFQQWQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEK
490 500 510 520 530 540
460 470 480 490 500 510
pF1KA0 FRKEHMELVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRKEHMELVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQ
550 560 570 580 590 600
520 530 540 550 560 570
pF1KA0 LSELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPG
610 620 630 640 650 660
580 590 600 610 620 630
pF1KA0 APPCLGMGLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APPCLGMGLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQ
670 680 690 700 710 720
640 650 660 670 680 690
pF1KA0 VFRILDLEDFEKMFSAYQRHQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFRILDLEDFEKMFSAYQRHQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKL
730 740 750 760 770 780
700 710 720 730 740 750
pF1KA0 SNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMS
790 800 810 820 830 840
760 770 780 790 800 810
pF1KA0 RIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMN
850 860 870 880 890 900
820 830 840 850 860 870
pF1KA0 KGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAA
910 920 930 940 950 960
880 890 900 910 920 930
pF1KA0 KVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQ
970 980 990 1000 1010 1020
940 950 960 970 980 990
pF1KA0 LNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRAR
1030 1040 1050 1060 1070 1080
1000 1010 1020 1030 1040 1050
pF1KA0 MEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRS
1090 1100 1110 1120 1130 1140
1060
pF1KA0 GSQALEVTRERAINRLNY
::::::::::::::::::
XP_006 GSQALEVTRERAINRLNY
1150 1160
>>NP_056160 (OMIM: 606627) disheveled-associated activat (1067 aa)
initn: 7075 init1: 5956 opt: 7077 Z-score: 2965.8 bits: 560.5 E(85289): 1.9e-158
Smith-Waterman score: 7077; 99.9% identity (99.9% similar) in 1068 aa overlap (1-1068:1-1067)
10 20 30 40 50 60
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQKELGSTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQKELGSTEDI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 YLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 AILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNIS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_056 LLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEV-LEYQRR
850 860 870 880 890
910 920 930 940 950 960
pF1KA0 QVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGI
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 FDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEG
960 970 980 990 1000 1010
1030 1040 1050 1060
pF1KA0 GEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
1020 1030 1040 1050 1060
>>NP_001257449 (OMIM: 606626) disheveled-associated acti (1068 aa)
initn: 4394 init1: 2175 opt: 4887 Z-score: 2054.9 bits: 391.9 E(85289): 1e-107
Smith-Waterman score: 4887; 68.4% identity (86.6% similar) in 1081 aa overlap (1-1068:1-1068)
10 20 30 40 50
pF1KA0 MAPRKRSHHGLGFL-CCFGGSDIPEINLR----DNHPLQFMEFSSPIPNAEELNIRFAEL
::::::. .:..:. ::: ..: :::. : .: :: :: . :.: .:::.. :.::
NP_001 MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 VDELDLTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSL
:::::::::.:::::::: ::::::::::::.::. :: :::::..:::..::::: .::
NP_001 VDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEE-NKGATSWPEFYIDQLNSMAARKSL
70 80 90 100 110
120 130 140 150 160 170
pF1KA0 YAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHT
:...:: : :....:.:::::::.:::::::::.:.::.:.::::..::. : ::::::
NP_001 LALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA0 SLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKK
:::::::::::::::::::::. :.:..::::: ::: ::::::::::::::::::::::
NP_001 SLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 VLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLE
::::::::: ::.::::::::.:.::.: :::::::.:::::::::::::. ::: ..:.
NP_001 VLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 FRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKS
::::::::::::::::::::::.:::. ::.:::::::.::::.::.:.::..:::::::
NP_001 FRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 ASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERG
:.::::: .:.: ..:::: ..:.:::::::::::.:. : : :::::.::::.:...:
NP_001 ATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KA0 VDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLE
::: .::::::.::.: ::.::::::::..::::.:::: :: ..::.:::::..:: :
NP_001 QDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQE
420 430 440 450 460 470
480 490 500 510 520
pF1KA0 KEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVS-------SPPPPGGP
:::::.::::::.:: .:. : .:.. :::.:.::: ::: : :: ::::
NP_001 KEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCASIPGGPSPGAPGGP
480 490 500 510 520 530
530 540 550 560 570 580
pF1KA0 LTLSSSMTTNDLPPPPPP-LPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYP
. ::. . ::::::: :: . :::::: ::::::: ::: :: :: .: : :.
NP_001 F--PSSVPGSLLPPPPPPPLPGGMLPPPPPP-LPPGGPPPPPGPPP-LGAIMPPPGAPM-
540 550 560 570 580 590
590 600 610 620 630 640
pF1KA0 SSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAY
. :.:: .:::.. :::::: :: :... ::::.:::: .::.::::::.:. ::::
NP_001 --GLALKKKSIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTFSAY
600 610 620 630 640 650
650 660 670 680 690 700
pF1KA0 QRHQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQED
::.::: . .: .. :::::::::::::::: ::::.:::::.::..::: ::::::
NP_001 QRQQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQED
660 670 680 690 700 710
710 720 730 740 750 760
pF1KA0 LAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKK
: ::::::::::.:::::::::::::::..:::.:::::.:::::.:::::::.:.::::
NP_001 LPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKK
720 730 740 750 760 770
770 780 790 800 810 820
pF1KA0 FQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNK
: ::.::.::::::: .:.:. :: :.:.:::.::.::.:::::::.::::...::::
NP_001 FAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNK
780 790 800 810 820 830
830 840 850 860 870 880
pF1KA0 IADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRG
:::::::::.::.:::::: :.:...:..::. ::. .:.:::::..::.::...:: :
NP_001 IADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSG
840 850 860 870 880 890
890 900 910 920 930 940
pF1KA0 LRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGE
:.:::.:::::. : .:.:::: :.:.::::.:::::..:: : ::.: :.::. ::::
NP_001 LKAVETELEYQKSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGE
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KA0 HDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQ
. .:.:::::::::: :::: :::.:. : ::..::::::::::::.::::::::: .:.
NP_001 EAGKIQPDEFFGIFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRK
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KA0 RKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLN
: . ::.:::::::::::::::::::: ::::.::: .: . .::: :..::
NP_001 AK-----ENSEESGEFDDLVSALRSGEVFDKDLSKLKRNRKRITNQMTDSSRERPITKLN
1020 1030 1040 1050 1060
pF1KA0 Y
.
NP_001 F
>>XP_006715106 (OMIM: 606627) PREDICTED: disheveled-asso (1077 aa)
initn: 4438 init1: 4438 opt: 4496 Z-score: 1892.3 bits: 361.8 E(85289): 1.2e-98
Smith-Waterman score: 7067; 99.2% identity (99.2% similar) in 1077 aa overlap (1-1068:1-1077)
10 20 30 40 50 60
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQ---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQELITNPSQQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060
pF1KA0 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
1030 1040 1050 1060 1070
>>XP_006715105 (OMIM: 606627) PREDICTED: disheveled-asso (1077 aa)
initn: 4438 init1: 4438 opt: 4496 Z-score: 1892.3 bits: 361.8 E(85289): 1.2e-98
Smith-Waterman score: 7067; 99.2% identity (99.2% similar) in 1077 aa overlap (1-1068:1-1077)
10 20 30 40 50 60
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQ---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQELITNPSQQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060
pF1KA0 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
1030 1040 1050 1060 1070
>>XP_006715109 (OMIM: 606627) PREDICTED: disheveled-asso (1077 aa)
initn: 4438 init1: 4438 opt: 4496 Z-score: 1892.3 bits: 361.8 E(85289): 1.2e-98
Smith-Waterman score: 7067; 99.2% identity (99.2% similar) in 1077 aa overlap (1-1068:1-1077)
10 20 30 40 50 60
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQ---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQELITNPSQQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060
pF1KA0 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
1030 1040 1050 1060 1070
>>XP_006715108 (OMIM: 606627) PREDICTED: disheveled-asso (1077 aa)
initn: 4438 init1: 4438 opt: 4496 Z-score: 1892.3 bits: 361.8 E(85289): 1.2e-98
Smith-Waterman score: 7067; 99.2% identity (99.2% similar) in 1077 aa overlap (1-1068:1-1077)
10 20 30 40 50 60
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQ
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQ---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQELITNPSQQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQER
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADT
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAV
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060
pF1KA0 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
1030 1040 1050 1060 1070
>>XP_016866119 (OMIM: 606627) PREDICTED: disheveled-asso (1100 aa)
initn: 4438 init1: 4438 opt: 4496 Z-score: 1892.1 bits: 361.9 E(85289): 1.2e-98
Smith-Waterman score: 7067; 99.2% identity (99.2% similar) in 1077 aa overlap (1-1068:24-1100)
10 20 30
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFME
:::::::::::::::::::::::::::::::::::::
XP_016 MKIKDHNEDLGHLSADAPWPAVTMAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFME
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 FSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 WPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 LNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 AVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 MSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 DDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 WQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHME
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 LVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTG
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 PVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGM
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 GLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDL
610 620 630 640 650 660
640 650 660 670 680
pF1KA0 EDFEKMFSAYQRHQ---------KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKL
:::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_016 EDFEKMFSAYQRHQELITNPSQQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 KLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYE
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA0 MSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNF
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA0 MNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPE
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA0 AAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELE
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA0 DQLNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERR
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KA0 ARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRK
1030 1040 1050 1060 1070 1080
1050 1060
pF1KA0 RSGSQALEVTRERAINRLNY
::::::::::::::::::::
XP_016 RSGSQALEVTRERAINRLNY
1090 1100
>>XP_006715102 (OMIM: 606627) PREDICTED: disheveled-asso (1176 aa)
initn: 4438 init1: 4438 opt: 4496 Z-score: 1891.8 bits: 361.9 E(85289): 1.2e-98
Smith-Waterman score: 7067; 99.2% identity (99.2% similar) in 1077 aa overlap (1-1068:100-1176)
10 20 30
pF1KA0 MAPRKRSHHGLGFLCCFGGSDIPEINLRDN
::::::::::::::::::::::::::::::
XP_006 CPRPISCGMDTDHNEDLGHLSADAPWPAVTMAPRKRSHHGLGFLCCFGGSDIPEINLRDN
70 80 90 100 110 120
40 50 60 70 80 90
pF1KA0 HPLQFMEFSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HPLQFMEFSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQED
130 140 150 160 170 180
100 110 120 130 140 150
pF1KA0 PNKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIE
190 200 210 220 230 240
160 170 180 190 200 210
pF1KA0 LEGLTCLLNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEGLTCLLNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRT
250 260 270 280 290 300
220 230 240 250 260 270
pF1KA0 ENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDE
310 320 330 340 350 360
280 290 300 310 320 330
pF1KA0 VNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDF
370 380 390 400 410 420
340 350 360 370 380 390
pF1KA0 FEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKR
430 440 450 460 470 480
400 410 420 430 440 450
pF1KA0 NGGYFQQWQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGYFQQWQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEK
490 500 510 520 530 540
460 470 480 490 500 510
pF1KA0 FRKEHMELVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRKEHMELVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQ
550 560 570 580 590 600
520 530 540 550 560 570
pF1KA0 LSELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPG
610 620 630 640 650 660
580 590 600 610 620 630
pF1KA0 APPCLGMGLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APPCLGMGLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQ
670 680 690 700 710 720
640 650 660 670 680
pF1KA0 VFRILDLEDFEKMFSAYQRHQ---------KELGSTEDIYLASRKVKELSVIDGRRAQNC
::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_006 VFRILDLEDFEKMFSAYQRHQELITNPSQQKELGSTEDIYLASRKVKELSVIDGRRAQNC
730 740 750 760 770 780
690 700 710 720 730 740
pF1KA0 IILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMAR
790 800 810 820 830 840
750 760 770 780 790 800
pF1KA0 ADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEV
850 860 870 880 890 900
810 820 830 840 850 860
pF1KA0 ILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPS
910 920 930 940 950 960
870 880 890 900 910 920
pF1KA0 ELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSS
970 980 990 1000 1010 1020
930 940 950 960 970 980
pF1KA0 FSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRR
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030 1040
pF1KA0 KEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLC
1090 1100 1110 1120 1130 1140
1050 1060
pF1KA0 KLKRSRKRSGSQALEVTRERAINRLNY
:::::::::::::::::::::::::::
XP_006 KLKRSRKRSGSQALEVTRERAINRLNY
1150 1160 1170
1068 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:46:56 2016 done: Wed Nov 2 18:46:58 2016
Total Scan time: 12.920 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]