FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0382, 1544 aa 1>>>pF1KA0382 1544 - 1544 aa - 1544 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6824+/-0.00055; mu= 8.5033+/- 0.034 mean_var=266.3470+/-55.688, 0's: 0 Z-trim(115.9): 278 B-trim: 1046 in 1/51 Lambda= 0.078587 statistics sampled from 26311 (26651) to 26311 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.312), width: 16 Scan time: 16.660 The best scores are: opt bits E(85289) NP_056128 (OMIM: 604763) rho guanine nucleotide ex (1544) 10158 1167.2 0 NP_001185594 (OMIM: 604763) rho guanine nucleotide (1525) 9750 1120.9 0 XP_011541022 (OMIM: 604763) PREDICTED: rho guanine (1441) 9491 1091.5 0 NP_001288013 (OMIM: 604763) rho guanine nucleotide (1441) 9491 1091.5 0 XP_016872910 (OMIM: 604763) PREDICTED: rho guanine (1441) 9491 1091.5 0 XP_016872911 (OMIM: 604763) PREDICTED: rho guanine (1401) 8494 978.5 0 XP_016872909 (OMIM: 604763) PREDICTED: rho guanine (1485) 8494 978.5 0 XP_006718868 (OMIM: 604763) PREDICTED: rho guanine (1519) 8013 924.0 0 XP_016858410 (OMIM: 605708) PREDICTED: rho guanine (1552) 2413 289.1 1.9e-76 XP_006711725 (OMIM: 605708) PREDICTED: rho guanine (1568) 2405 288.2 3.7e-76 XP_006711724 (OMIM: 605708) PREDICTED: rho guanine (1569) 2353 282.3 2.2e-74 XP_016858413 (OMIM: 605708) PREDICTED: rho guanine (1523) 1857 226.0 1.8e-57 XP_016858411 (OMIM: 605708) PREDICTED: rho guanine (1528) 1857 226.0 1.8e-57 NP_055599 (OMIM: 605708) rho guanine nucleotide ex (1522) 1687 206.8 1.1e-51 XP_006711728 (OMIM: 605708) PREDICTED: rho guanine (1538) 1687 206.8 1.2e-51 NP_937879 (OMIM: 605708) rho guanine nucleotide ex (1562) 1682 206.2 1.7e-51 XP_006711723 (OMIM: 605708) PREDICTED: rho guanine (1578) 1682 206.2 1.7e-51 XP_011508487 (OMIM: 605708) PREDICTED: rho guanine (1574) 1620 199.2 2.3e-49 XP_016858412 (OMIM: 605708) PREDICTED: rho guanine (1523) 1619 199.1 2.4e-49 XP_011508488 (OMIM: 605708) PREDICTED: rho guanine (1539) 1619 199.1 2.4e-49 XP_011508489 (OMIM: 605708) PREDICTED: rho guanine (1485) 1614 198.5 3.5e-49 XP_006711726 (OMIM: 605708) PREDICTED: rho guanine (1559) 1614 198.5 3.6e-49 XP_005245686 (OMIM: 605708) PREDICTED: rho guanine (1563) 1614 198.5 3.6e-49 XP_016858409 (OMIM: 605708) PREDICTED: rho guanine (1568) 1614 198.5 3.6e-49 XP_006711722 (OMIM: 605708) PREDICTED: rho guanine (1579) 1614 198.5 3.6e-49 XP_005245690 (OMIM: 605708) PREDICTED: rho guanine (1141) 1428 177.3 6.5e-43 XP_011508491 (OMIM: 605708) PREDICTED: rho guanine ( 945) 1394 173.3 8.3e-42 NP_945328 (OMIM: 601855) rho guanine nucleotide ex ( 879) 1259 158.0 3.2e-37 NP_004697 (OMIM: 601855) rho guanine nucleotide ex ( 912) 1259 158.0 3.3e-37 NP_945353 (OMIM: 601855) rho guanine nucleotide ex ( 927) 1259 158.0 3.3e-37 XP_005259447 (OMIM: 601855) PREDICTED: rho guanine ( 981) 1259 158.0 3.4e-37 XP_005259443 (OMIM: 601855) PREDICTED: rho guanine (1041) 1253 157.4 5.7e-37 XP_011525770 (OMIM: 601855) PREDICTED: rho guanine ( 985) 1252 157.2 6e-37 XP_016858288 (OMIM: 607560) PREDICTED: rho guanine ( 919) 525 74.8 3.7e-12 XP_006711686 (OMIM: 607560) PREDICTED: rho guanine ( 920) 525 74.8 3.7e-12 XP_006711688 (OMIM: 607560) PREDICTED: rho guanine ( 920) 525 74.8 3.7e-12 XP_016858287 (OMIM: 607560) PREDICTED: rho guanine ( 920) 525 74.8 3.7e-12 XP_006711687 (OMIM: 607560) PREDICTED: rho guanine ( 920) 525 74.8 3.7e-12 XP_006711689 (OMIM: 607560) PREDICTED: rho guanine ( 920) 525 74.8 3.7e-12 NP_004714 (OMIM: 607560) rho guanine nucleotide ex ( 958) 519 74.1 6.1e-12 XP_016858286 (OMIM: 607560) PREDICTED: rho guanine ( 968) 519 74.1 6.2e-12 XP_005245651 (OMIM: 607560) PREDICTED: rho guanine ( 969) 519 74.1 6.2e-12 XP_005245650 (OMIM: 607560) PREDICTED: rho guanine ( 969) 519 74.1 6.2e-12 XP_005245649 (OMIM: 607560) PREDICTED: rho guanine ( 969) 519 74.1 6.2e-12 XP_016858285 (OMIM: 607560) PREDICTED: rho guanine ( 978) 519 74.1 6.2e-12 XP_006711685 (OMIM: 607560) PREDICTED: rho guanine ( 979) 519 74.1 6.2e-12 XP_005245647 (OMIM: 607560) PREDICTED: rho guanine ( 981) 519 74.1 6.2e-12 XP_005245648 (OMIM: 607560) PREDICTED: rho guanine ( 981) 519 74.1 6.2e-12 NP_001155856 (OMIM: 607560) rho guanine nucleotide ( 985) 519 74.1 6.2e-12 NP_001155855 (OMIM: 607560) rho guanine nucleotide ( 986) 519 74.1 6.2e-12 >>NP_056128 (OMIM: 604763) rho guanine nucleotide exchan (1544 aa) initn: 10158 init1: 10158 opt: 10158 Z-score: 6239.0 bits: 1167.2 E(85289): 0 Smith-Waterman score: 10158; 100.0% identity (100.0% similar) in 1544 aa overlap (1-1544:1-1544) 10 20 30 40 50 60 pF1KA0 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KA0 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS :::::::::::::::::::::::::::::::::::::::::::: NP_056 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS 1510 1520 1530 1540 >>NP_001185594 (OMIM: 604763) rho guanine nucleotide exc (1525 aa) initn: 10035 init1: 9737 opt: 9750 Z-score: 5989.1 bits: 1120.9 E(85289): 0 Smith-Waterman score: 10001; 98.8% identity (98.8% similar) in 1544 aa overlap (1-1544:1-1525) 10 20 30 40 50 60 pF1KA0 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPT------------- 10 20 30 40 70 80 90 100 110 120 pF1KA0 SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ------GLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KA0 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KA0 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KA0 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KA0 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT 290 300 310 320 330 340 370 380 390 400 410 420 pF1KA0 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR 350 360 370 380 390 400 430 440 450 460 470 480 pF1KA0 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL 410 420 430 440 450 460 490 500 510 520 530 540 pF1KA0 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK 470 480 490 500 510 520 550 560 570 580 590 600 pF1KA0 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI 530 540 550 560 570 580 610 620 630 640 650 660 pF1KA0 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY 590 600 610 620 630 640 670 680 690 700 710 720 pF1KA0 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ 650 660 670 680 690 700 730 740 750 760 770 780 pF1KA0 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG 710 720 730 740 750 760 790 800 810 820 830 840 pF1KA0 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ 770 780 790 800 810 820 850 860 870 880 890 900 pF1KA0 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS 830 840 850 860 870 880 910 920 930 940 950 960 pF1KA0 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KA0 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KA0 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KA0 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KA0 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KA0 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KA0 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG 1250 1260 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KA0 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH 1310 1320 1330 1340 1350 1360 1390 1400 1410 1420 1430 1440 pF1KA0 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KA0 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 pF1KA0 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS :::::::::::::::::::::::::::::::::::::::::::: NP_001 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS 1490 1500 1510 1520 >>XP_011541022 (OMIM: 604763) PREDICTED: rho guanine nuc (1441 aa) initn: 9491 init1: 9491 opt: 9491 Z-score: 5830.7 bits: 1091.5 E(85289): 0 Smith-Waterman score: 9491; 100.0% identity (100.0% similar) in 1441 aa overlap (104-1544:1-1441) 80 90 100 110 120 130 pF1KA0 IIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKL :::::::::::::::::::::::::::::: XP_011 MRAGVQTGDRIIKVNGTLVTHSNHLEVVKL 10 20 30 140 150 160 170 180 190 pF1KA0 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ 220 230 240 250 260 270 380 390 400 410 420 430 pF1KA0 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KA0 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KA0 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK 400 410 420 430 440 450 560 570 580 590 600 610 pF1KA0 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KA0 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA 520 530 540 550 560 570 680 690 700 710 720 730 pF1KA0 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE 580 590 600 610 620 630 740 750 760 770 780 790 pF1KA0 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN 640 650 660 670 680 690 800 810 820 830 840 850 pF1KA0 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR 700 710 720 730 740 750 860 870 880 890 900 910 pF1KA0 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ 760 770 780 790 800 810 920 930 940 950 960 970 pF1KA0 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KA0 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KA0 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KA0 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD 1000 1010 1020 1030 1040 1050 1160 1170 1180 1190 1200 1210 pF1KA0 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER 1060 1070 1080 1090 1100 1110 1220 1230 1240 1250 1260 1270 pF1KA0 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS 1120 1130 1140 1150 1160 1170 1280 1290 1300 1310 1320 1330 pF1KA0 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE 1180 1190 1200 1210 1220 1230 1340 1350 1360 1370 1380 1390 pF1KA0 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP 1240 1250 1260 1270 1280 1290 1400 1410 1420 1430 1440 1450 pF1KA0 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ 1300 1310 1320 1330 1340 1350 1460 1470 1480 1490 1500 1510 pF1KA0 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD 1360 1370 1380 1390 1400 1410 1520 1530 1540 pF1KA0 LEHLKKVEESYTILCQRLAGSALTDKHSDKS ::::::::::::::::::::::::::::::: XP_011 LEHLKKVEESYTILCQRLAGSALTDKHSDKS 1420 1430 1440 >>NP_001288013 (OMIM: 604763) rho guanine nucleotide exc (1441 aa) initn: 9491 init1: 9491 opt: 9491 Z-score: 5830.7 bits: 1091.5 E(85289): 0 Smith-Waterman score: 9491; 100.0% identity (100.0% similar) in 1441 aa overlap (104-1544:1-1441) 80 90 100 110 120 130 pF1KA0 IIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKL :::::::::::::::::::::::::::::: NP_001 MRAGVQTGDRIIKVNGTLVTHSNHLEVVKL 10 20 30 140 150 160 170 180 190 pF1KA0 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ 220 230 240 250 260 270 380 390 400 410 420 430 pF1KA0 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KA0 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KA0 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK 400 410 420 430 440 450 560 570 580 590 600 610 pF1KA0 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KA0 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA 520 530 540 550 560 570 680 690 700 710 720 730 pF1KA0 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE 580 590 600 610 620 630 740 750 760 770 780 790 pF1KA0 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN 640 650 660 670 680 690 800 810 820 830 840 850 pF1KA0 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR 700 710 720 730 740 750 860 870 880 890 900 910 pF1KA0 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ 760 770 780 790 800 810 920 930 940 950 960 970 pF1KA0 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KA0 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KA0 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KA0 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD 1000 1010 1020 1030 1040 1050 1160 1170 1180 1190 1200 1210 pF1KA0 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER 1060 1070 1080 1090 1100 1110 1220 1230 1240 1250 1260 1270 pF1KA0 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS 1120 1130 1140 1150 1160 1170 1280 1290 1300 1310 1320 1330 pF1KA0 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE 1180 1190 1200 1210 1220 1230 1340 1350 1360 1370 1380 1390 pF1KA0 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP 1240 1250 1260 1270 1280 1290 1400 1410 1420 1430 1440 1450 pF1KA0 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ 1300 1310 1320 1330 1340 1350 1460 1470 1480 1490 1500 1510 pF1KA0 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD 1360 1370 1380 1390 1400 1410 1520 1530 1540 pF1KA0 LEHLKKVEESYTILCQRLAGSALTDKHSDKS ::::::::::::::::::::::::::::::: NP_001 LEHLKKVEESYTILCQRLAGSALTDKHSDKS 1420 1430 1440 >>XP_016872910 (OMIM: 604763) PREDICTED: rho guanine nuc (1441 aa) initn: 9491 init1: 9491 opt: 9491 Z-score: 5830.7 bits: 1091.5 E(85289): 0 Smith-Waterman score: 9491; 100.0% identity (100.0% similar) in 1441 aa overlap (104-1544:1-1441) 80 90 100 110 120 130 pF1KA0 IIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKL :::::::::::::::::::::::::::::: XP_016 MRAGVQTGDRIIKVNGTLVTHSNHLEVVKL 10 20 30 140 150 160 170 180 190 pF1KA0 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ 220 230 240 250 260 270 380 390 400 410 420 430 pF1KA0 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS 280 290 300 310 320 330 440 450 460 470 480 490 pF1KA0 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL 340 350 360 370 380 390 500 510 520 530 540 550 pF1KA0 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK 400 410 420 430 440 450 560 570 580 590 600 610 pF1KA0 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS 460 470 480 490 500 510 620 630 640 650 660 670 pF1KA0 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA 520 530 540 550 560 570 680 690 700 710 720 730 pF1KA0 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE 580 590 600 610 620 630 740 750 760 770 780 790 pF1KA0 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN 640 650 660 670 680 690 800 810 820 830 840 850 pF1KA0 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR 700 710 720 730 740 750 860 870 880 890 900 910 pF1KA0 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ 760 770 780 790 800 810 920 930 940 950 960 970 pF1KA0 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KA0 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KA0 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KA0 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD 1000 1010 1020 1030 1040 1050 1160 1170 1180 1190 1200 1210 pF1KA0 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER 1060 1070 1080 1090 1100 1110 1220 1230 1240 1250 1260 1270 pF1KA0 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS 1120 1130 1140 1150 1160 1170 1280 1290 1300 1310 1320 1330 pF1KA0 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE 1180 1190 1200 1210 1220 1230 1340 1350 1360 1370 1380 1390 pF1KA0 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP 1240 1250 1260 1270 1280 1290 1400 1410 1420 1430 1440 1450 pF1KA0 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ 1300 1310 1320 1330 1340 1350 1460 1470 1480 1490 1500 1510 pF1KA0 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD 1360 1370 1380 1390 1400 1410 1520 1530 1540 pF1KA0 LEHLKKVEESYTILCQRLAGSALTDKHSDKS ::::::::::::::::::::::::::::::: XP_016 LEHLKKVEESYTILCQRLAGSALTDKHSDKS 1420 1430 1440 >>XP_016872911 (OMIM: 604763) PREDICTED: rho guanine nuc (1401 aa) initn: 8482 init1: 8482 opt: 8494 Z-score: 5219.9 bits: 978.5 E(85289): 0 Smith-Waterman score: 9149; 97.2% identity (97.2% similar) in 1441 aa overlap (104-1544:1-1401) 80 90 100 110 120 130 pF1KA0 IIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKL :::::::::::::::::::::::::::::: XP_016 MRAGVQTGDRIIKVNGTLVTHSNHLEVVKL 10 20 30 140 150 160 170 180 190 pF1KA0 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 MGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQL :::::::::::::::::::::::::::: XP_016 MGEENNVVHNQKVEILRKMLQKEQERLQ-------------------------------- 100 110 260 270 280 290 300 310 pF1KA0 SKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 --------DGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSG 120 130 140 150 160 170 320 330 340 350 360 370 pF1KA0 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQ 180 190 200 210 220 230 380 390 400 410 420 430 pF1KA0 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRS 240 250 260 270 280 290 440 450 460 470 480 490 pF1KA0 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTL 300 310 320 330 340 350 500 510 520 530 540 550 pF1KA0 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMK 360 370 380 390 400 410 560 570 580 590 600 610 pF1KA0 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNS 420 430 440 450 460 470 620 630 640 650 660 670 pF1KA0 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGA 480 490 500 510 520 530 680 690 700 710 720 730 pF1KA0 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTE 540 550 560 570 580 590 740 750 760 770 780 790 pF1KA0 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVIN 600 610 620 630 640 650 800 810 820 830 840 850 pF1KA0 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVR 660 670 680 690 700 710 860 870 880 890 900 910 pF1KA0 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQ 720 730 740 750 760 770 920 930 940 950 960 970 pF1KA0 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNY 780 790 800 810 820 830 980 990 1000 1010 1020 1030 pF1KA0 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRD 840 850 860 870 880 890 1040 1050 1060 1070 1080 1090 pF1KA0 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATD 900 910 920 930 940 950 1100 1110 1120 1130 1140 1150 pF1KA0 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGD 960 970 980 990 1000 1010 1160 1170 1180 1190 1200 1210 pF1KA0 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAER 1020 1030 1040 1050 1060 1070 1220 1230 1240 1250 1260 1270 pF1KA0 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKS 1080 1090 1100 1110 1120 1130 1280 1290 1300 1310 1320 1330 pF1KA0 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTE 1140 1150 1160 1170 1180 1190 1340 1350 1360 1370 1380 1390 pF1KA0 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENP 1200 1210 1220 1230 1240 1250 1400 1410 1420 1430 1440 1450 pF1KA0 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQ 1260 1270 1280 1290 1300 1310 1460 1470 1480 1490 1500 1510 pF1KA0 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEAD 1320 1330 1340 1350 1360 1370 1520 1530 1540 pF1KA0 LEHLKKVEESYTILCQRLAGSALTDKHSDKS ::::::::::::::::::::::::::::::: XP_016 LEHLKKVEESYTILCQRLAGSALTDKHSDKS 1380 1390 1400 >>XP_016872909 (OMIM: 604763) PREDICTED: rho guanine nuc (1485 aa) initn: 8780 init1: 8482 opt: 8494 Z-score: 5219.6 bits: 978.5 E(85289): 0 Smith-Waterman score: 9659; 96.2% identity (96.2% similar) in 1544 aa overlap (1-1544:1-1485) 10 20 30 40 50 60 pF1KA0 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPT------------- 10 20 30 40 70 80 90 100 110 120 pF1KA0 SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ------GLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KA0 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KA0 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ ::::::::::::::::::::::::::::::::::::::::: XP_016 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQ------------------- 170 180 190 200 250 260 270 280 290 300 pF1KA0 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS ::::::::::::::::::::::::::::::::::::::: XP_016 ---------------------DGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS 210 220 230 240 310 320 330 340 350 360 pF1KA0 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT 250 260 270 280 290 300 370 380 390 400 410 420 pF1KA0 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR 310 320 330 340 350 360 430 440 450 460 470 480 pF1KA0 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL 370 380 390 400 410 420 490 500 510 520 530 540 pF1KA0 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK 430 440 450 460 470 480 550 560 570 580 590 600 pF1KA0 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI 490 500 510 520 530 540 610 620 630 640 650 660 pF1KA0 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY 550 560 570 580 590 600 670 680 690 700 710 720 pF1KA0 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ 610 620 630 640 650 660 730 740 750 760 770 780 pF1KA0 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG 670 680 690 700 710 720 790 800 810 820 830 840 pF1KA0 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ 730 740 750 760 770 780 850 860 870 880 890 900 pF1KA0 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS 790 800 810 820 830 840 910 920 930 940 950 960 pF1KA0 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV 850 860 870 880 890 900 970 980 990 1000 1010 1020 pF1KA0 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM 910 920 930 940 950 960 1030 1040 1050 1060 1070 1080 pF1KA0 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI 970 980 990 1000 1010 1020 1090 1100 1110 1120 1130 1140 pF1KA0 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK 1030 1040 1050 1060 1070 1080 1150 1160 1170 1180 1190 1200 pF1KA0 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS 1090 1100 1110 1120 1130 1140 1210 1220 1230 1240 1250 1260 pF1KA0 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK 1150 1160 1170 1180 1190 1200 1270 1280 1290 1300 1310 1320 pF1KA0 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG 1210 1220 1230 1240 1250 1260 1330 1340 1350 1360 1370 1380 pF1KA0 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH 1270 1280 1290 1300 1310 1320 1390 1400 1410 1420 1430 1440 pF1KA0 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ 1330 1340 1350 1360 1370 1380 1450 1460 1470 1480 1490 1500 pF1KA0 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ 1390 1400 1410 1420 1430 1440 1510 1520 1530 1540 pF1KA0 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS :::::::::::::::::::::::::::::::::::::::::::: XP_016 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS 1450 1460 1470 1480 >>XP_006718868 (OMIM: 604763) PREDICTED: rho guanine nuc (1519 aa) initn: 8000 init1: 8000 opt: 8013 Z-score: 4924.8 bits: 924.0 E(85289): 0 Smith-Waterman score: 9935; 98.4% identity (98.4% similar) in 1544 aa overlap (1-1544:1-1519) 10 20 30 40 50 60 pF1KA0 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT :::::::: ::::::::::::::::::::::::::: XP_006 RPSSDNAD-------------------------DTQSLVGSPSTRIAPHIIGAEDDDFGT 310 320 330 370 380 390 400 410 420 pF1KA0 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA0 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA0 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA0 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA0 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGY 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA0 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQ 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA0 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA0 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA0 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA0 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKV 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA0 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA0 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA0 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KA0 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTS 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KA0 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLK 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KA0 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTG 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KA0 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KA0 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 pF1KA0 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 pF1KA0 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS :::::::::::::::::::::::::::::::::::::::::::: XP_006 SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS 1480 1490 1500 1510 >>XP_016858410 (OMIM: 605708) PREDICTED: rho guanine nuc (1552 aa) initn: 1789 init1: 621 opt: 2413 Z-score: 1493.3 bits: 289.1 E(85289): 1.9e-76 Smith-Waterman score: 2442; 33.9% identity (62.4% similar) in 1575 aa overlap (34-1533:7-1485) 10 20 30 40 50 60 pF1KA0 TQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEESR- :...:..: .. .:. . :: :.. . XP_016 MSVRLPQSIDRLSS--LSSLGDSAPERKSPSHHRQP 10 20 30 70 80 90 100 110 pF1KA0 ---SEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNG :: ::::::::::::..:::.::::: :.::::. ::::.:::. ::::::::: XP_016 SDASETTGLVQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNG 40 50 60 70 80 90 120 130 140 150 160 170 pF1KA0 TLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSP :.::.:.:::::::::::.:::::. : :.: : ... :. ... .. :: : XP_016 TMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSMGISGLQQDPSPAGAPRITSVIPSPPPP 100 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 GASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEI .:::.: . .. :... ..:::.::..:...:: . : :.:.::. : ..: XP_016 PPLPPPQRITGPKPL--QDPEVQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQI 160 170 180 190 200 210 240 250 260 270 280 290 pF1KA0 QEAKKHIPQLQEQLSKATGSAQDGAVV---TPSRPLGDTLTVSEAETDPGDVLGRTDCSS . :.... ::: .... ::.. : . : .:: :... : : : : : XP_016 EGARRRVTQLQLKIQQETGGSVDILPLYGDTSQRPSEGRLSLDSQEGDSGLDSGTERFPS 220 230 240 250 260 270 300 310 320 330 340 pF1KA0 GDAS---RPS--SDNA-DSPKSGP--KERIYLEENPEKSET-IQDTDTQSLVGSPSTRIA . : : : :: . :::...: :. .. . :.. . .: :.. ::. XP_016 LSESLMNRNSVLSDPGLDSPRTSPVIMARVAQHHRRQGSDAAVPSTGDQGVDQSPK---- 280 290 300 310 320 350 360 370 380 390 400 pF1KA0 PHIIGAEDD-DFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLY : ::: :.: : : ... . ::..: ::::::::.:::... :: ::. :: :: XP_016 PLIIGPEEDYDPGYFNNESD---IIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLC 330 340 350 360 370 380 410 420 430 440 450 460 pF1KA0 SDLYKHTNSKETRRIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQ ...:.... :..: . .. ..::...: :.:..:. ..:....: . :: : . XP_016 AEVYQQASPKDSRSLGKDIWNIFLEKNAPLRVKIPEMLQAEIDSRLRN--SEDA-RGVLC 390 400 410 420 430 440 470 480 490 500 510 520 pF1KA0 TMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKI :: . ::.:....:.: ::..:: .: :: . : : :: ::. .: . XP_016 EAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLDLDGDPLR-----ERQVAEKQLAAL 450 460 470 480 490 530 540 550 560 570 pF1KA0 EEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKE--PRNLEHKRGR-------IGFLPK ..: . :::.:. :.... ::.: :....: : : .: . :.:: XP_016 GDIL---SKYEEDRSAPMDFALNTYMSHAGIRLREARPSNTAEKAQSAPDKDKWLPFFPK 500 510 520 530 540 550 580 590 600 610 620 630 pF1KA0 IKQSM--KKDKEGEEKGKRRGFPSILGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSS :.: ::.:.. : :: . . .: :. :. . . : . .:. .. .. . XP_016 TKKSSNSKKEKDALEDKKRNPILKYIGKPKSSSQSIKPGNVRNI-IQHFENNQQYD---- 560 570 580 590 600 640 650 660 670 680 pF1KA0 VSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGASFSQEGGKE------------- .::: . .: ... .. .. .: : . : : : .: .: XP_016 -APEP-GTQRLSTGSFPEDLLESD----SSRSEIRLGRSESLKGREEMKRSRKAENVPRS 610 620 630 640 650 660 690 700 710 720 730 740 pF1KA0 -NDTGSKQVGETSAPGDTLDGTPRTLNT-VFDFPPPPLDQVQEEECEVERVTEHGTPKPF .:. ..:.. .. ... .:.: .. : ::. . .. ... .: XP_016 RSDVDMDAAAEATRLHQSASSSTSSLSTRSLENPTPPF---------TPKMGRRSIESPS 670 680 690 700 710 750 760 770 780 790 pF1KA0 RKFDSVAFGESQSEDEQFE-NDLETDPP--NWQQLVSREVLLGLKPCEIKRQEVINELFY : . .. ::. . .::: .: :::. :...:. :: :: ::::::::: XP_016 LGFCTDTLLPHLLEDDLGQLSDLEPEPDAQNWQHTVGKDVVAGLTQREIDRQEVINELFV 720 730 740 750 760 770 800 810 820 830 840 850 pF1KA0 TERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVRKRNE :: .:.:::.::: .::::...:... :: ..: :: .....: . : :: .:. : XP_016 TEASHLRTLRVLDLIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEAMKKLRE--E 780 790 800 810 820 830 860 870 880 890 900 910 pF1KA0 TSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQDAES .: .:.. .:. :.::..:.:...:: ::: : .:::.::..:.:.:::: :.:.::: XP_016 GPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAES 840 850 860 870 880 890 920 930 940 950 960 970 pF1KA0 NPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPT-EREKVKKAADHCRQILNYVNQ .: ::::::.:.: ..:::::::::::..: :.:: : :.::. .: :.::.::.:::. XP_016 HPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNE 900 910 920 930 940 950 980 990 1000 1010 1020 1030 pF1KA0 AVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRDKTI :::..::..::: ::.:::...:. . : . :...:::: :::::::::.:....:::. XP_016 AVKQTENRHRLEGYQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTL 960 970 980 990 1000 1010 1040 1050 1060 1070 1080 1090 pF1KA0 DLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATDNKA ::..:::::.::::::::..:.:.:::: ....:::.:::::.::..::.:.::::..: XP_016 DLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRA 1020 1030 1040 1050 1060 1070 1100 1110 1120 1130 1140 1150 pF1KA0 LFVISMSDNGA-QIYELVAQTVSEKTVWQDLICRMA-ASVKEQSTKPIPLPQSTPGEGDN .:.: : : ::::::: : :.:..:..:. . . .... .. :.:. :: . XP_016 FFIICTSKLGPPQIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPMPVHPPPPGPREP 1080 1090 1100 1110 1120 1130 1160 1170 1180 1190 1200 pF1KA0 DEEDPSKLKEEQHGISVT-GLQSPDRDLGLESTLISSKPQSHSL----STSGKSEVRDLF .. :. . : .: : :.. : .. . . . : :..: ..: XP_016 AQQGPTPSRVELDDSDVFHGEPEPEELPGGTGSQQRVQGKHQVLLEDPEQEGSAEEEELG 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA0 VAERQFAKEQHTDGTLKEVG--EDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQL : :: . . . ..:.: :. : : .::... :..:.. .: XP_016 VLP---CPSTSLDGENRGIRTRNPIHLAFPG---PLFMEGLADSALEDVENLRHLILWSL 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 pF1KA0 --GLT--EKSVQE---DWQHFPRYRTASQGP----QTDSVIQNSENIKAYHSG-EGHMPF : : ...:: : : .... : . .. ..:. .. .: ::. : XP_016 LPGHTMETQAAQEPEDDLTPTPSVISVTSHPWDPGSPGQAPPGGEGDNTQLAGLEGERPE 1250 1260 1270 1280 1290 1300 1320 1330 1340 1350 1360 pF1KA0 RTGTGDIATC----YSPRTSTESF--APRDSVGLAPQDSQASNILVMDHMIMTPEMPTME . :.. : ::: . .. .:. . .:: .:..... ... :. . XP_016 QE---DMGLCSLEHLPPRTRNSGIWESPELDRNLA-EDASSTEAAGGYKVVRKAEVAGSK 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KA0 PEGGLDDSGEHFFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESST .: .::. :. .: : .:.. . .:: . .. . .::: XP_016 VVPALPESGQ---------SEPGPPEVEGGT---------KATGNCFYVSMPSGPPDSST 1370 1380 1390 1400 1430 1440 1450 1460 1470 1480 pF1KA0 DEEVASSLTLQPMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFE :. : ::. : .: : :: . : .: : XP_016 DHSEA------PMSP-PQPDSLPAGQTEPQPQLQGGNDDPRRPS---------------- 1410 1420 1430 1440 1490 1500 1510 1520 1530 1540 pF1KA0 IQSPSSCADSQ-SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS .:: : : . ..:.. :... :..:: .: .. : . :.: XP_016 -RSPPSLALRDVGMIFHTIEQLTLKLNRLKDMELAHRELLKSLGGESSGGTTPVGSFHTE 1450 1460 1470 1480 1490 1500 XP_016 AARWTDGSLSPPAKEPLASDSRNSHELGPCPEDGSDAPLEDSTADAAASPGP 1510 1520 1530 1540 1550 >>XP_006711725 (OMIM: 605708) PREDICTED: rho guanine nuc (1568 aa) initn: 1789 init1: 621 opt: 2405 Z-score: 1488.4 bits: 288.2 E(85289): 3.7e-76 Smith-Waterman score: 2434; 34.1% identity (62.4% similar) in 1562 aa overlap (43-1533:36-1501) 20 30 40 50 60 70 pF1KA0 PLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEESRSEIYGLVQRC : : .: .. .. :. :: :::::: XP_006 PQSIDRSASKKQSHLSSPIAAWLSSLSSLGDSAPERKSPSHHRQPSDA--SETTGLVQRC 10 20 30 40 50 60 80 90 100 110 120 130 pF1KA0 VIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVK ::::::..:::.::::: :.::::. ::::.:::. ::::::::::.::.:.:::::: XP_006 VIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVK 70 80 90 100 110 120 140 150 160 170 180 190 pF1KA0 LIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPV :::::.:::::. : :.: : ... :. ... .. :: : .:::.: XP_006 LIKSGAYVALTLLGSSPSSMGISGLQQDPSPAGAPRITSVIPSPPPPPPLPPPQRITGPK 130 140 150 160 170 180 200 210 220 230 240 250 pF1KA0 LMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQ . . . :... ..:::.::..:...:: . : :.:.::. : ..:. :.... ::: . XP_006 PLQDPE--VQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRRVTQLQLK 190 200 210 220 230 240 260 270 280 290 300 pF1KA0 LSKATGSAQDGAVV---TPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDAS---RPS--S ... ::.. : . : .:: :... : : : : : . : : : : XP_006 IQQETGGSVDILPLYGDTSQRPSEGRLSLDSQEGDSGLDSGTERFPSLSESLMNRNSVLS 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 DNA-DSPKSGP--KERIYLEENPEKSET-IQDTDTQSLVGSPSTRIAPHIIGAEDD-DFG : . :::...: :. .. . :.. . .: :.. ::. : ::: :.: : : XP_006 DPGLDSPRTSPVIMARVAQHHRRQGSDAAVPSTGDQGVDQSPK----PLIIGPEEDYDPG 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 TEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETR ... . ::..: ::::::::.:::... :: ::. :: :: ...:.... :..: XP_006 YFNNESD---IIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQASPKDSR 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 RIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRH . .. ..::...: :.:..:. ..:....: . :: : . :: . ::.:.. XP_006 SLGKDIWNIFLEKNAPLRVKIPEMLQAEIDSRLRN--SEDA-RGVLCEAQEAAMPEIQEQ 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 LEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEED ..:.: ::..:: .: :: : : : .:: ::. .: . ..: . ::: XP_006 IHDYRTKRTLGLGSLYGENDLLDL--DGDPL---RERQVAEKQLAALGDIL---SKYEED 480 490 500 510 520 540 550 560 570 580 pF1KA0 KSSTMQYVILMYMKHLGVKVKE--PRNLEHKRGR-------IGFLPKIKQSM--KKDKEG .:. :.... ::.: :....: : : .: . :.:: :.: ::.:.. XP_006 RSAPMDFALNTYMSHAGIRLREARPSNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDA 530 540 550 560 570 580 590 600 610 620 630 640 pF1KA0 EEKGKRRGFPSILGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQ : :: . . .: :. :. . . : . .:. .. .. . .::: . .: XP_006 LEDKKRNPILKYIGKPKSSSQSIKPGNVRNI-IQHFENNQQYD-----APEP-GTQRLST 590 600 610 620 630 650 660 670 680 690 pF1KA0 SGLANEGTDAGYLPANSMSSVASGASFSQEGGKE--------------NDTGSKQVGETS ... .. .. .: : . : : : .: .: .:. ..:.. XP_006 GSFPEDLLESD----SSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAT 640 650 660 670 680 690 700 710 720 730 740 750 pF1KA0 APGDTLDGTPRTLNT-VFDFPPPPLDQVQEEECEVERVTEHGTPKPFRKFDSVAFGESQS .. ... .:.: .. : ::. . .. ... .: : . .. XP_006 RLHQSASSSTSSLSTRSLENPTPPF---------TPKMGRRSIESPSLGFCTDTLLPHLL 700 710 720 730 740 760 770 780 790 800 810 pF1KA0 EDEQFE-NDLETDPP--NWQQLVSREVLLGLKPCEIKRQEVINELFYTERAHVRTLKVLD ::. . .::: .: :::. :...:. :: :: ::::::::: :: .:.:::.::: XP_006 EDDLGQLSDLEPEPDAQNWQHTVGKDVVAGLTQREIDRQEVINELFVTEASHLRTLRVLD 750 760 770 780 790 800 820 830 840 850 860 870 pF1KA0 QVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVRKRNETSVIDQIGEDLLT .::::...:... :: ..: :: .....: . : :: .:. : .: .:.. .:. XP_006 LIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEAMKKLRE--EGPIIKEISDLMLA 810 820 830 840 850 860 880 890 900 910 920 930 pF1KA0 WFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDII :.::..:.:...:: ::: : .:::.::..:.:.:::: :.:.:::.: ::::::.:.: XP_006 RFDGPAREELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLI 870 880 890 900 910 920 940 950 960 970 980 pF1KA0 PTQMQRLTKYPLLLDNIAKYTEWPT-EREKVKKAADHCRQILNYVNQAVKEAENKQRLED ..:::::::::::..: :.:: : :.::. .: :.::.::.:::.:::..::..::: XP_006 ISEMQRLTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEG 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 pF1KA0 YQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRDKTIDLYTLLLEDILVL ::.:::...:. . : . :...:::: :::::::::.:....:::.::..:::::.::: XP_006 YQKRLDATALERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVL 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 pF1KA0 LQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATDNKALFVISMSDNGA-Q :::::..:.:.:::: ....:::.:::::.::..::.:.::::..:.:.: : : : XP_006 LQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLIRSVATDKRAFFIICTSKLGPPQ 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 pF1KA0 IYELVAQTVSEKTVWQDLICRMA-ASVKEQSTKPIPLPQSTPGEGDNDEEDPSKLKEEQH :::::: : :.:..:..:. . . .... .. :.:. :: . .. :. . : XP_006 IYELVALTSSDKNTWMELLEEAVRNATRHPGAAPMPVHPPPPGPREPAQQGPTPSRVELD 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 pF1KA0 GISVT-GLQSPDRDLGLESTLISSKPQSHSL----STSGKSEVRDLFVAERQFAKEQHTD .: : :.. : .. . . . : :..: ..: : : XP_006 DSDVFHGEPEPEELPGGTGSQQRVQGKHQVLLEDPEQEGSAEEEELGVLP---CPSTSLD 1170 1180 1190 1200 1210 1230 1240 1250 1260 1270 pF1KA0 GTLKEVG--EDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQL--GLT--EKSVQE : . . . ..:.: :. : : .::... :..:.. .: : : ...:: XP_006 GENRGIRTRNPIHLAFPG---PLFMEGLADSALEDVENLRHLILWSLLPGHTMETQAAQE 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 ---DWQHFPRYRTASQGP----QTDSVIQNSENIKAYHSG-EGHMPFRTGTGDIATC--- : : .... : . .. ..:. .. .: ::. : . :.. : XP_006 PEDDLTPTPSVISVTSHPWDPGSPGQAPPGGEGDNTQLAGLEGERPEQE---DMGLCSLE 1280 1290 1300 1310 1320 1330 1330 1340 1350 1360 1370 1380 pF1KA0 -YSPRTSTESF--APRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFF ::: . .. .:. . .:: .:..... ... :. . .: .::. XP_006 HLPPRTRNSGIWESPELDRNLA-EDASSTEAAGGYKVVRKAEVAGSKVVPALPESGQ--- 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 DAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPM :. .: : .:.. . .:: . .. . .::::. : :: XP_006 ------SEPGPPEVEGGT---------KATGNCFYVSMPSGPPDSSTDHSEA------PM 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KA0 TGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQ-S . : .: : :: . : .: : .:: : : . . XP_006 SP-PQPDSLPAGQTEPQPQLQGGNDDPRRPS-----------------RSPPSLALRDVG 1430 1440 1450 1460 1510 1520 1530 1540 pF1KA0 QIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS .:.. :... :..:: .: .. : . :.: XP_006 MIFHTIEQLTLKLNRLKDMELAHRELLKSLGGESSGGTTPVGSFHTEAARWTDGSLSPPA 1470 1480 1490 1500 1510 1520 XP_006 KEPLASDSRNSHELGPCPEDGSDAPLEDSTADAAASPGP 1530 1540 1550 1560 1544 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:41:24 2016 done: Sat Nov 5 06:41:26 2016 Total Scan time: 16.660 Total Display time: 0.940 Function used was FASTA [36.3.4 Apr, 2011]