FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0386, 1068 aa 1>>>pF1KA0386 1068 - 1068 aa - 1068 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4721+/-0.000397; mu= 11.5146+/- 0.025 mean_var=121.4817+/-24.719, 0's: 0 Z-trim(113.7): 40 B-trim: 0 in 0/59 Lambda= 0.116364 statistics sampled from 23188 (23219) to 23188 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.272), width: 16 Scan time: 14.040 The best scores are: opt bits E(85289) NP_055537 (OMIM: 611410,616515) protein FAM65B iso (1068) 6876 1166.5 0 XP_011513314 (OMIM: 611410,616515) PREDICTED: prot (1102) 6876 1166.5 0 XP_006715342 (OMIM: 611410,616515) PREDICTED: prot (1018) 4190 715.5 3.7e-205 NP_001332960 (OMIM: 611410,616515) protein FAM65B (1018) 4190 715.5 3.7e-205 XP_011513310 (OMIM: 611410,616515) PREDICTED: prot (1018) 4190 715.5 3.7e-205 NP_001332961 (OMIM: 611410,616515) protein FAM65B (1018) 4190 715.5 3.7e-205 XP_016867012 (OMIM: 611410,616515) PREDICTED: prot (1018) 4190 715.5 3.7e-205 XP_011513311 (OMIM: 611410,616515) PREDICTED: prot (1018) 4190 715.5 3.7e-205 XP_011513309 (OMIM: 611410,616515) PREDICTED: prot (1047) 4190 715.6 3.8e-205 NP_001273374 (OMIM: 611410,616515) protein FAM65B (1047) 4190 715.6 3.8e-205 XP_006715338 (OMIM: 611410,616515) PREDICTED: prot (1052) 4190 715.6 3.8e-205 XP_016867016 (OMIM: 611410,616515) PREDICTED: prot ( 591) 2356 407.6 1.1e-112 NP_056948 (OMIM: 611410,616515) protein FAM65B iso ( 591) 2356 407.6 1.1e-112 XP_016867015 (OMIM: 611410,616515) PREDICTED: prot ( 591) 2356 407.6 1.1e-112 XP_016867014 (OMIM: 611410,616515) PREDICTED: prot ( 613) 2356 407.6 1.1e-112 NP_001273376 (OMIM: 611410,616515) protein FAM65B ( 613) 2356 407.6 1.1e-112 XP_006715344 (OMIM: 611410,616515) PREDICTED: prot ( 625) 2356 407.6 1.2e-112 XP_016867013 (OMIM: 611410,616515) PREDICTED: prot ( 642) 2356 407.6 1.2e-112 NP_001273375 (OMIM: 611410,616515) protein FAM65B ( 647) 2356 407.6 1.2e-112 >>NP_055537 (OMIM: 611410,616515) protein FAM65B isoform (1068 aa) initn: 6876 init1: 6876 opt: 6876 Z-score: 6240.9 bits: 1166.5 E(85289): 0 Smith-Waterman score: 6876; 99.8% identity (100.0% similar) in 1068 aa overlap (1-1068:1-1068) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_055 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_055 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 1030 1040 1050 1060 >>XP_011513314 (OMIM: 611410,616515) PREDICTED: protein (1102 aa) initn: 6876 init1: 6876 opt: 6876 Z-score: 6240.7 bits: 1166.5 E(85289): 0 Smith-Waterman score: 6876; 99.8% identity (100.0% similar) in 1068 aa overlap (1-1068:35-1102) 10 20 30 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQE :::::::::::::::::::::::::::::: XP_011 SRLHWIRNRPWRDRIRRRQLNRLPTRLPEIMLVGSQSFSPGGPNGIIRSQSFAGFSGLQE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 RRSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 VHQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 RLQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 LAGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTEL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 KGLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDMEDMTASSGAG :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_011 KGLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDMTASSGAG 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 NKAAALQRRMSMYSQGTPETPTFKDHSFFRWLHPSPDKPRRLSVLSALQDTFFAKLHRSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKAAALQRRMSMYSQGTPETPTFKDHSFFRWLHPSPDKPRRLSVLSALQDTFFAKLHRSR 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA0 SFSDLPSLRPSPKAVLELYSNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSDLPSLRPSPKAVLELYSNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA0 PSNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA0 PASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKR 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA0 LTSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQ 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA0 EVMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA0 VFSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQ 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA0 YCTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YCTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKK 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA0 LSLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: XP_011 LSLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDRAE 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA0 PLLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSD 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA0 LAPSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAPSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTN 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA0 LQLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFP 1030 1040 1050 1060 1070 1080 1060 pF1KA0 RDCVKVGGRHGTEVATAF :::::::::::::::::: XP_011 RDCVKVGGRHGTEVATAF 1090 1100 >>XP_006715342 (OMIM: 611410,616515) PREDICTED: protein (1018 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.3 bits: 715.5 E(85289): 3.7e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:1-1018) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_006 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFF- 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG ::::::::::: XP_006 -------------------------------------------------SNLPDDIFENG 360 370 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_006 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 920 930 940 950 960 970 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 980 990 1000 1010 >>NP_001332960 (OMIM: 611410,616515) protein FAM65B isof (1018 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.3 bits: 715.5 E(85289): 3.7e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:1-1018) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_001 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFF- 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG ::::::::::: NP_001 -------------------------------------------------SNLPDDIFENG 360 370 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 920 930 940 950 960 970 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 980 990 1000 1010 >>XP_011513310 (OMIM: 611410,616515) PREDICTED: protein (1018 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.3 bits: 715.5 E(85289): 3.7e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:1-1018) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFF- 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG ::::::::::: XP_011 -------------------------------------------------SNLPDDIFENG 360 370 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_011 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 920 930 940 950 960 970 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 980 990 1000 1010 >>NP_001332961 (OMIM: 611410,616515) protein FAM65B isof (1018 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.3 bits: 715.5 E(85289): 3.7e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:1-1018) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_001 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFF- 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG ::::::::::: NP_001 -------------------------------------------------SNLPDDIFENG 360 370 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 920 930 940 950 960 970 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 980 990 1000 1010 >>XP_016867012 (OMIM: 611410,616515) PREDICTED: protein (1018 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.3 bits: 715.5 E(85289): 3.7e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:1-1018) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFF- 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG ::::::::::: XP_016 -------------------------------------------------SNLPDDIFENG 360 370 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_016 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 920 930 940 950 960 970 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 980 990 1000 1010 >>XP_011513311 (OMIM: 611410,616515) PREDICTED: protein (1018 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.3 bits: 715.5 E(85289): 3.7e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:1-1018) 10 20 30 40 50 60 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRCNSFIENSSALKKPQAKLKKMHNLGH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNNNPPKEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEIN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYEIFMKYGRQRWKLKGKI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 INDLGTIKLNLEITWYPFDMEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFR :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 INDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFF- 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 WLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG ::::::::::: XP_011 -------------------------------------------------SNLPDDIFENG 360 370 430 440 450 460 470 480 pF1KA0 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAAEEKMPLSLSFSDLPNGDCALTSHSTGSPSNSTNPEITITPAEFNLSSLASQNEGMDD 380 390 400 410 420 430 490 500 510 520 530 540 pF1KA0 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEA 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA0 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLQESEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFL 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA0 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESA 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA0 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LESFDFLNTSDFDEEEDGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTED 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA0 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQI 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA0 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEA 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA0 SFARTVNKEYPGLADPVFRTLVSQILDQAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_011 SFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSSSLSSEVVTVFQYYSYFTSHGVSDLE 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA0 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEA 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA0 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSD 920 930 940 950 960 970 1030 1040 1050 1060 pF1KA0 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEEIRNVASETLLSLGEDGRLAYEQLDKFPRDCVKVGGRHGTEVATAF 980 990 1000 1010 >>XP_011513309 (OMIM: 611410,616515) PREDICTED: protein (1047 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.1 bits: 715.6 E(85289): 3.8e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:30-1047) 10 20 30 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQER ::::::::::::::::::::::::::::::: XP_011 MQFFDAEELLVDEEDDVFGEGLPTRLPEIMLVGSQSFSPGGPNGIIRSQSFAGFSGLQER 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 RSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLEV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 HQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 LQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 AGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 GLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDMEDMTASSGAGN ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: XP_011 GLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDMTASSGAGN 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 KAAALQRRMSMYSQGTPETPTFKDHSFFRWLHPSPDKPRRLSVLSALQDTFFAKLHRSRS :::::::::::::::::::::::::::: XP_011 KAAALQRRMSMYSQGTPETPTFKDHSFF-------------------------------- 370 380 400 410 420 430 440 450 pF1KA0 FSDLPSLRPSPKAVLELYSNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGSP :::::::::::::::::::::::::::::::::::::::::: XP_011 ------------------SNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGSP 390 400 410 420 430 460 470 480 490 500 510 pF1KA0 SNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRKP 440 450 460 470 480 490 520 530 540 550 560 570 pF1KA0 ASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKRL 500 510 520 530 540 550 580 590 600 610 620 630 pF1KA0 TSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQE 560 570 580 590 600 610 640 650 660 670 680 690 pF1KA0 VMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADSV 620 630 640 650 660 670 700 710 720 730 740 750 pF1KA0 FSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQY 680 690 700 710 720 730 760 770 780 790 800 810 pF1KA0 CTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKKL 740 750 760 770 780 790 820 830 840 850 860 870 pF1KA0 SLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDQAEP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_011 SLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDRAEP 800 810 820 830 840 850 880 890 900 910 920 930 pF1KA0 LLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSDL 860 870 880 890 900 910 940 950 960 970 980 990 pF1KA0 APSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNL 920 930 940 950 960 970 1000 1010 1020 1030 1040 1050 pF1KA0 QLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFPR 980 990 1000 1010 1020 1030 1060 pF1KA0 DCVKVGGRHGTEVATAF ::::::::::::::::: XP_011 DCVKVGGRHGTEVATAF 1040 >>NP_001273374 (OMIM: 611410,616515) protein FAM65B isof (1047 aa) initn: 4188 init1: 4188 opt: 4190 Z-score: 3804.1 bits: 715.6 E(85289): 3.8e-205 Smith-Waterman score: 6427; 95.1% identity (95.3% similar) in 1068 aa overlap (1-1068:30-1047) 10 20 30 pF1KA0 MLVGSQSFSPGGPNGIIRSQSFAGFSGLQER ::::::::::::::::::::::::::::::: NP_001 MQFFDAEELLVDEEDDVFGEGLPTRLPEIMLVGSQSFSPGGPNGIIRSQSFAGFSGLQER 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 RSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSRCNSFIENSSALKKPQAKLKKMHNLGHKNNNPPKEPQPKRVEEVYRALKNGLDEYLEV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 HQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 LQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 AGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGFARLCPGDQYEIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 GLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDMEDMTASSGAGN ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: NP_001 GLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDMTASSGAGN 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 KAAALQRRMSMYSQGTPETPTFKDHSFFRWLHPSPDKPRRLSVLSALQDTFFAKLHRSRS :::::::::::::::::::::::::::: NP_001 KAAALQRRMSMYSQGTPETPTFKDHSFF-------------------------------- 370 380 400 410 420 430 440 450 pF1KA0 FSDLPSLRPSPKAVLELYSNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGSP :::::::::::::::::::::::::::::::::::::::::: NP_001 ------------------SNLPDDIFENGKAAEEKMPLSLSFSDLPNGDCALTSHSTGSP 390 400 410 420 430 460 470 480 490 500 510 pF1KA0 SNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNSTNPEITITPAEFNLSSLASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRKP 440 450 460 470 480 490 520 530 540 550 560 570 pF1KA0 ASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASAPSEACRRQSSGAGAEHLFLENDVAEALLQESEEASELKPVELDTSEGNITKQLVKRL 500 510 520 530 540 550 580 590 600 610 620 630 pF1KA0 TSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQE 560 570 580 590 600 610 640 650 660 670 680 690 pF1KA0 VMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEEDGDEVCNVGGGADSV 620 630 640 650 660 670 700 710 720 730 740 750 pF1KA0 FSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQY 680 690 700 710 720 730 760 770 780 790 800 810 pF1KA0 CTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKKL 740 750 760 770 780 790 820 830 840 850 860 870 pF1KA0 SLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDQAEP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_001 SLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDRAEP 800 810 820 830 840 850 880 890 900 910 920 930 pF1KA0 LLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSSSLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSDL 860 870 880 890 900 910 940 950 960 970 980 990 pF1KA0 APSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNL 920 930 940 950 960 970 1000 1010 1020 1030 1040 1050 pF1KA0 QLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDGRLAYEQLDKFPR 980 990 1000 1010 1020 1030 1060 pF1KA0 DCVKVGGRHGTEVATAF ::::::::::::::::: NP_001 DCVKVGGRHGTEVATAF 1040 1068 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:31:55 2016 done: Thu Nov 3 09:31:57 2016 Total Scan time: 14.040 Total Display time: 0.540 Function used was FASTA [36.3.4 Apr, 2011]