FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0397, 1006 aa 1>>>pF1KA0397 1006 - 1006 aa - 1006 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4891+/-0.000361; mu= 17.6272+/- 0.023 mean_var=131.3422+/-27.332, 0's: 0 Z-trim(118.0): 71 B-trim: 1381 in 2/50 Lambda= 0.111911 statistics sampled from 30417 (30500) to 30417 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.358), width: 16 Scan time: 16.210 The best scores are: opt bits E(85289) NP_001091979 (OMIM: 611418) small G protein signal (1006) 6868 1121.0 0 XP_011522410 (OMIM: 611418) PREDICTED: small G pro (1012) 6695 1093.1 0 XP_016880963 (OMIM: 611418) PREDICTED: small G pro (1052) 6579 1074.4 0 XP_016880964 (OMIM: 611418) PREDICTED: small G pro (1047) 6536 1067.4 0 XP_011522407 (OMIM: 611418) PREDICTED: small G pro (1058) 6406 1046.5 0 NP_055668 (OMIM: 611418) small G protein signaling (1051) 3968 652.8 2.7e-186 XP_011522404 (OMIM: 611418) PREDICTED: small G pro (1097) 3968 652.9 2.8e-186 XP_011522405 (OMIM: 611418) PREDICTED: small G pro (1092) 3925 645.9 3.4e-184 XP_016880965 (OMIM: 611418) PREDICTED: small G pro ( 785) 3795 624.8 5.6e-178 XP_011522408 (OMIM: 611418) PREDICTED: small G pro (1057) 3795 624.9 6.9e-178 XP_011522406 (OMIM: 611418) PREDICTED: small G pro (1087) 3795 624.9 7.1e-178 XP_011522403 (OMIM: 611418) PREDICTED: small G pro (1103) 3795 624.9 7.2e-178 XP_011522409 (OMIM: 611418) PREDICTED: small G pro (1042) 2606 432.9 4.2e-120 NP_001091968 (OMIM: 611417) small G protein signal (1032) 1326 226.3 6.8e-58 NP_597711 (OMIM: 611417) small G protein signaling (1087) 1326 226.3 7.1e-58 NP_001091967 (OMIM: 611417) small G protein signal (1093) 1326 226.3 7.1e-58 NP_001035037 (OMIM: 611417) small G protein signal (1148) 1326 226.3 7.3e-58 XP_011522412 (OMIM: 611418) PREDICTED: small G pro ( 526) 850 149.2 5.7e-35 XP_011522411 (OMIM: 611418) PREDICTED: small G pro ( 529) 850 149.2 5.7e-35 XP_011536984 (OMIM: 612662) PREDICTED: TBC1 domain ( 445) 445 83.7 2.4e-15 XP_006719630 (OMIM: 612662) PREDICTED: TBC1 domain ( 445) 445 83.7 2.4e-15 XP_016875317 (OMIM: 612662) PREDICTED: TBC1 domain ( 530) 445 83.8 2.8e-15 XP_016875316 (OMIM: 612662) PREDICTED: TBC1 domain ( 547) 445 83.8 2.8e-15 XP_016875314 (OMIM: 612662) PREDICTED: TBC1 domain ( 575) 445 83.8 2.9e-15 XP_016875315 (OMIM: 612662) PREDICTED: TBC1 domain ( 575) 445 83.8 2.9e-15 XP_011536982 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 445 83.8 3e-15 XP_016875313 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 445 83.8 3e-15 XP_006719629 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 445 83.8 3e-15 XP_011536981 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 445 83.8 3e-15 NP_001139685 (OMIM: 612662) TBC1 domain family mem ( 674) 445 83.9 3.3e-15 NP_001139686 (OMIM: 612662) TBC1 domain family mem ( 682) 445 83.9 3.3e-15 XP_006719628 (OMIM: 612662) PREDICTED: TBC1 domain ( 682) 445 83.9 3.3e-15 NP_073608 (OMIM: 612662) TBC1 domain family member ( 691) 445 83.9 3.3e-15 XP_006719627 (OMIM: 612662) PREDICTED: TBC1 domain ( 699) 445 83.9 3.4e-15 NP_001258773 (OMIM: 616637) TBC1 domain family mem ( 392) 402 76.7 2.7e-13 XP_011522626 (OMIM: 616637) PREDICTED: TBC1 domain ( 396) 402 76.7 2.7e-13 NP_001258774 (OMIM: 616637) TBC1 domain family mem ( 405) 402 76.7 2.8e-13 XP_016879677 (OMIM: 616637) PREDICTED: TBC1 domain ( 462) 402 76.8 3.1e-13 XP_011522625 (OMIM: 616637) PREDICTED: TBC1 domain ( 521) 402 76.8 3.4e-13 XP_016879676 (OMIM: 616637) PREDICTED: TBC1 domain ( 543) 402 76.8 3.5e-13 XP_016879675 (OMIM: 616637) PREDICTED: TBC1 domain ( 599) 402 76.9 3.7e-13 XP_011522624 (OMIM: 616637) PREDICTED: TBC1 domain ( 753) 402 77.0 4.4e-13 XP_005257107 (OMIM: 616637) PREDICTED: TBC1 domain ( 766) 402 77.0 4.4e-13 XP_005257106 (OMIM: 616637) PREDICTED: TBC1 domain ( 767) 402 77.0 4.4e-13 XP_006721757 (OMIM: 616637) PREDICTED: TBC1 domain ( 767) 402 77.0 4.4e-13 NP_061893 (OMIM: 616637) TBC1 domain family member ( 767) 402 77.0 4.4e-13 NP_001161694 (OMIM: 616659) TBC1 domain family mem ( 615) 393 75.4 1e-12 NP_078958 (OMIM: 616659) TBC1 domain family member ( 648) 393 75.5 1.1e-12 NP_002527 (OMIM: 311240) TBC1 domain family member ( 688) 390 75.0 1.6e-12 NP_001258775 (OMIM: 616637) TBC1 domain family mem ( 278) 305 60.9 1.1e-08 >>NP_001091979 (OMIM: 611418) small G protein signaling (1006 aa) initn: 6868 init1: 6868 opt: 6868 Z-score: 5996.3 bits: 1121.0 E(85289): 0 Smith-Waterman score: 6868; 100.0% identity (100.0% similar) in 1006 aa overlap (1-1006:1-1006) 10 20 30 40 50 60 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IYPGHRHEHNAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYPGHRHEHNAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 RLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 ARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DDLEPPEPQDPEDSRPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDLEPPEPQDPEDSRPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SSLDEGQSVGFEEEDGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSLDEGQSVGFEEEDGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 AYTIELLDTVALNLHRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYTIELLDTVALNLHRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMC 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 DLLAPLLVTLDNDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLAPLLVTLDNDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 QNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYRE 910 920 930 940 950 960 970 980 990 1000 pF1KA0 IIRDNNMDFTDIIKFFNERAEHHDAQEILRIARDLVHKVQMLIENK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIRDNNMDFTDIIKFFNERAEHHDAQEILRIARDLVHKVQMLIENK 970 980 990 1000 >>XP_011522410 (OMIM: 611418) PREDICTED: small G protein (1012 aa) initn: 6682 init1: 6682 opt: 6695 Z-score: 5845.3 bits: 1093.1 E(85289): 0 Smith-Waterman score: 6695; 99.1% identity (99.4% similar) in 991 aa overlap (1-991:1-989) 10 20 30 40 50 60 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 IYPGHRHEHNAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYPGHRHEHNAGDMIEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 RLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLPLRLLCESMKRQIVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVWSKYQKDKKNYKELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 ARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARYQQVLAEWKACEVVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 DDLEPPEPQDPEDSRPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDLEPPEPQDPEDSRPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SSLDEGQSVGFEEEDGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSLDEGQSVGFEEEDGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 AYTIELLDTVALNLHRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYTIELLDTVALNLHRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMC 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 DLLAPLLVTLDNDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLLAPLLVTLDNDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 QNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNGDYTHFYFCYRWFLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYRE 910 920 930 940 950 960 970 980 990 1000 pF1KA0 IIRDNNMDFTDIIKFFNERAEHHDAQEILRIARDLVHKVQMLIENK ::::::::::::::::: : : . :..: : XP_011 IIRDNNMDFTDIIKFFN--ALHVSPQNVLSITMPRRSCGLPGTSSTRYFPENHV 970 980 990 1000 1010 >>XP_016880963 (OMIM: 611418) PREDICTED: small G protein (1052 aa) initn: 6578 init1: 6578 opt: 6579 Z-score: 5743.8 bits: 1074.4 E(85289): 0 Smith-Waterman score: 6666; 95.5% identity (95.6% similar) in 1038 aa overlap (15-1006:15-1052) 10 20 30 40 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGA-------------- ::::::::::::::::::::::::::::::.: XP_016 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCAADPHQGLTRCQTPFT 10 20 30 40 50 60 50 60 70 pF1KA0 --------------------------------VEACLLHQLRRRAAGFLRSDKMAALFTK :::::::::::::::::::::::::::: XP_016 VQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALFTK 70 80 90 100 110 120 80 90 100 110 120 130 pF1KA0 VGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRT 130 140 150 160 170 180 140 150 160 170 180 190 pF1KA0 ALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHYWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHYWT 190 200 210 220 230 240 200 210 220 230 240 250 pF1KA0 DPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KA0 RTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYW 310 320 330 340 350 360 320 330 340 350 360 370 pF1KA0 DYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPR 370 380 390 400 410 420 380 390 400 410 420 430 pF1KA0 GQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDM 430 440 450 460 470 480 440 450 460 470 480 490 pF1KA0 IEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQ 490 500 510 520 530 540 500 510 520 530 540 550 pF1KA0 IVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYK 550 560 570 580 590 600 560 570 580 590 600 610 pF1KA0 ELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACE 610 620 630 640 650 660 620 630 640 650 660 670 pF1KA0 VVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDS 670 680 690 700 710 720 680 690 700 710 720 730 pF1KA0 RPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEE 730 740 750 760 770 780 740 750 760 770 780 790 pF1KA0 DGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNL 790 800 810 820 830 840 800 810 820 830 840 850 pF1KA0 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ 850 860 870 880 890 900 860 870 880 890 900 910 pF1KA0 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW 910 920 930 940 950 960 920 930 940 950 960 970 pF1KA0 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK 970 980 990 1000 1010 1020 980 990 1000 pF1KA0 FFNERAEHHDAQEILRIARDLVHKVQMLIENK :::::::::::::::::::::::::::::::: XP_016 FFNERAEHHDAQEILRIARDLVHKVQMLIENK 1030 1040 1050 >>XP_016880964 (OMIM: 611418) PREDICTED: small G protein (1047 aa) initn: 6535 init1: 6535 opt: 6536 Z-score: 5706.3 bits: 1067.4 E(85289): 0 Smith-Waterman score: 6623; 95.4% identity (95.5% similar) in 1031 aa overlap (15-999:15-1045) 10 20 30 40 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGA-------------- ::::::::::::::::::::::::::::::.: XP_016 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCAADPHQGLTRCQTPFT 10 20 30 40 50 60 50 60 70 pF1KA0 --------------------------------VEACLLHQLRRRAAGFLRSDKMAALFTK :::::::::::::::::::::::::::: XP_016 VQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALFTK 70 80 90 100 110 120 80 90 100 110 120 130 pF1KA0 VGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRT 130 140 150 160 170 180 140 150 160 170 180 190 pF1KA0 ALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHYWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHYWT 190 200 210 220 230 240 200 210 220 230 240 250 pF1KA0 DPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KA0 RTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYW 310 320 330 340 350 360 320 330 340 350 360 370 pF1KA0 DYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPR 370 380 390 400 410 420 380 390 400 410 420 430 pF1KA0 GQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDM 430 440 450 460 470 480 440 450 460 470 480 490 pF1KA0 IEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQ 490 500 510 520 530 540 500 510 520 530 540 550 pF1KA0 IVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYK 550 560 570 580 590 600 560 570 580 590 600 610 pF1KA0 ELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACE 610 620 630 640 650 660 620 630 640 650 660 670 pF1KA0 VVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDS 670 680 690 700 710 720 680 690 700 710 720 730 pF1KA0 RPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEE 730 740 750 760 770 780 740 750 760 770 780 790 pF1KA0 DGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNL 790 800 810 820 830 840 800 810 820 830 840 850 pF1KA0 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ 850 860 870 880 890 900 860 870 880 890 900 910 pF1KA0 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW 910 920 930 940 950 960 920 930 940 950 960 970 pF1KA0 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK 970 980 990 1000 1010 1020 980 990 1000 pF1KA0 FFNERAEHHDAQEILRIARDLVHKVQMLIENK ::::::::::::::::::::::::: XP_016 FFNERAEHHDAQEILRIARDLVHKVLP 1030 1040 >>XP_011522407 (OMIM: 611418) PREDICTED: small G protein (1058 aa) initn: 6392 init1: 6392 opt: 6406 Z-score: 5592.9 bits: 1046.5 E(85289): 0 Smith-Waterman score: 6493; 94.5% identity (94.9% similar) in 1023 aa overlap (15-991:15-1035) 10 20 30 40 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGA-------------- ::::::::::::::::::::::::::::::.: XP_011 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCAADPHQGLTRCQTPFT 10 20 30 40 50 60 50 60 70 pF1KA0 --------------------------------VEACLLHQLRRRAAGFLRSDKMAALFTK :::::::::::::::::::::::::::: XP_011 VQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALFTK 70 80 90 100 110 120 80 90 100 110 120 130 pF1KA0 VGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWVRT 130 140 150 160 170 180 140 150 160 170 180 190 pF1KA0 ALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHYWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHYWT 190 200 210 220 230 240 200 210 220 230 240 250 pF1KA0 DPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQNS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KA0 RTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSVYW 310 320 330 340 350 360 320 330 340 350 360 370 pF1KA0 DYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLLPR 370 380 390 400 410 420 380 390 400 410 420 430 pF1KA0 GQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHNAGDM 430 440 450 460 470 480 440 450 460 470 480 490 pF1KA0 IEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQ 490 500 510 520 530 540 500 510 520 530 540 550 pF1KA0 IVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYK 550 560 570 580 590 600 560 570 580 590 600 610 pF1KA0 ELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACE 610 620 630 640 650 660 620 630 640 650 660 670 pF1KA0 VVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDS 670 680 690 700 710 720 680 690 700 710 720 730 pF1KA0 RPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEE 730 740 750 760 770 780 740 750 760 770 780 790 pF1KA0 DGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNL 790 800 810 820 830 840 800 810 820 830 840 850 pF1KA0 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ 850 860 870 880 890 900 860 870 880 890 900 910 pF1KA0 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW 910 920 930 940 950 960 920 930 940 950 960 970 pF1KA0 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK 970 980 990 1000 1010 1020 980 990 1000 pF1KA0 FFNERAEHHDAQEILRIARDLVHKVQMLIENK ::: : : . :..: : XP_011 FFN--ALHVSPQNVLSITMPRRSCGLPGTSSTRYFPENHV 1030 1040 1050 >>NP_055668 (OMIM: 611418) small G protein signaling mod (1051 aa) initn: 3968 init1: 3968 opt: 3968 Z-score: 3465.6 bits: 652.8 E(85289): 2.7e-186 Smith-Waterman score: 6686; 95.6% identity (95.7% similar) in 1038 aa overlap (14-1006:14-1051) 10 20 30 40 50 60 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA ::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI 370 380 390 400 410 420 430 pF1KA0 IYPGHRHEH---------------------------------------------NAGDMI ::::::::: .::::: NP_055 IYPGHRHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMI 430 440 450 460 470 480 440 450 460 470 480 490 pF1KA0 EMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI 490 500 510 520 530 540 500 510 520 530 540 550 pF1KA0 VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKE 550 560 570 580 590 600 560 570 580 590 600 610 pF1KA0 LELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEV 610 620 630 640 650 660 620 630 640 650 660 670 pF1KA0 VVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSR 670 680 690 700 710 720 680 690 700 710 720 730 pF1KA0 PKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEED 730 740 750 760 770 780 740 750 760 770 780 790 pF1KA0 GGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLH 790 800 810 820 830 840 800 810 820 830 840 850 pF1KA0 RIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQL 850 860 870 880 890 900 860 870 880 890 900 910 pF1KA0 AYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWF 910 920 930 940 950 960 920 930 940 950 960 970 pF1KA0 LLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKF 970 980 990 1000 1010 1020 980 990 1000 pF1KA0 FNERAEHHDAQEILRIARDLVHKVQMLIENK ::::::::::::::::::::::::::::::: NP_055 FNERAEHHDAQEILRIARDLVHKVQMLIENK 1030 1040 1050 >>XP_011522404 (OMIM: 611418) PREDICTED: small G protein (1097 aa) initn: 4241 init1: 3968 opt: 3968 Z-score: 3465.3 bits: 652.9 E(85289): 2.8e-186 Smith-Waterman score: 6474; 95.2% identity (95.4% similar) in 1009 aa overlap (44-1006:89-1097) 20 30 40 50 60 70 pF1KA0 WNVKKEVKQIMEEAVTRKFVHEDSSHIIALCG-AVEACLLHQLRRRAAGFLRSDKMAALF :. ::::::::::::::::::::::::::: XP_011 FTVQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALF 60 70 80 90 100 110 80 90 100 110 120 130 pF1KA0 TKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWV 120 130 140 150 160 170 140 150 160 170 180 190 pF1KA0 RTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHY 180 190 200 210 220 230 200 210 220 230 240 250 pF1KA0 WTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQ 240 250 260 270 280 290 260 270 280 290 300 310 pF1KA0 NSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSV 300 310 320 330 340 350 320 330 340 350 360 370 pF1KA0 YWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLL 360 370 380 390 400 410 380 390 400 410 420 pF1KA0 PRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEH--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHITI 420 430 440 450 460 470 430 440 pF1KA0 ------------------------------------------NAGDMIEMQGFGPSLPAW .::::::::::::::::: XP_011 NYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMIEMQGFGPSLPAW 480 490 500 510 520 530 450 460 470 480 490 500 pF1KA0 HLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHC 540 550 560 570 580 590 510 520 530 540 550 560 pF1KA0 RHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGI 600 610 620 630 640 650 570 580 590 600 610 620 pF1KA0 EHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPA 660 670 680 690 700 710 630 640 650 660 670 680 pF1KA0 TRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPKPEQEAGPGTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPKPEQEAGPGTP 720 730 740 750 760 770 690 700 710 720 730 740 pF1KA0 GTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGP 780 790 800 810 820 830 750 760 770 780 790 800 pF1KA0 AAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRIDKDVQRCDRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRIDKDVQRCDRN 840 850 860 870 880 890 810 820 830 840 850 860 pF1KA0 YWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAYSCFSHLMKRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAYSCFSHLMKRM 900 910 920 930 940 950 870 880 890 900 910 920 pF1KA0 SQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYED 960 970 980 990 1000 1010 930 940 950 960 970 980 pF1KA0 VFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQE 1020 1030 1040 1050 1060 1070 990 1000 pF1KA0 ILRIARDLVHKVQMLIENK ::::::::::::::::::: XP_011 ILRIARDLVHKVQMLIENK 1080 1090 >-- initn: 316 init1: 287 opt: 287 Z-score: 253.4 bits: 58.5 E(85289): 2.2e-07 Smith-Waterman score: 287; 97.8% identity (100.0% similar) in 46 aa overlap (1-46:1-46) 10 20 30 40 50 60 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA ::::::::::::::::::::::::::::::::::::::::::::.: XP_011 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCAADPHQGLTRCQTPFT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP XP_011 VQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALFTK 70 80 90 100 110 120 >>XP_011522405 (OMIM: 611418) PREDICTED: small G protein (1092 aa) initn: 4198 init1: 3925 opt: 3925 Z-score: 3427.8 bits: 645.9 E(85289): 3.4e-184 Smith-Waterman score: 6431; 95.2% identity (95.4% similar) in 1002 aa overlap (44-999:89-1090) 20 30 40 50 60 70 pF1KA0 WNVKKEVKQIMEEAVTRKFVHEDSSHIIALCG-AVEACLLHQLRRRAAGFLRSDKMAALF :. ::::::::::::::::::::::::::: XP_011 FTVQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALF 60 70 80 90 100 110 80 90 100 110 120 130 pF1KA0 TKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAPALSPQALKHVWV 120 130 140 150 160 170 140 150 160 170 180 190 pF1KA0 RTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCALEYTKLKTADHY 180 190 200 210 220 230 200 210 220 230 240 250 pF1KA0 WTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLAACARECVESLHQ 240 250 260 270 280 290 260 270 280 290 300 310 pF1KA0 NSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGTLGDSELEKSV 300 310 320 330 340 350 320 330 340 350 360 370 pF1KA0 YWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLSFLSCLENGLL 360 370 380 390 400 410 380 390 400 410 420 pF1KA0 PRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEH--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIYPGHRHEHITI 420 430 440 450 460 470 430 440 pF1KA0 ------------------------------------------NAGDMIEMQGFGPSLPAW .::::::::::::::::: XP_011 NYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMIEMQGFGPSLPAW 480 490 500 510 520 530 450 460 470 480 490 500 pF1KA0 HLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVSRAFYGWLAHC 540 550 560 570 580 590 510 520 530 540 550 560 pF1KA0 RHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELELLRQVYYGGI 600 610 620 630 640 650 570 580 590 600 610 620 pF1KA0 EHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVVRQREREAHPA 660 670 680 690 700 710 630 640 650 660 670 680 pF1KA0 TRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPKPEQEAGPGTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPKPEQEAGPGTP 720 730 740 750 760 770 690 700 710 720 730 740 pF1KA0 GTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGGGEEGSSGPGP 780 790 800 810 820 830 750 760 770 780 790 800 pF1KA0 AAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRIDKDVQRCDRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRIDKDVQRCDRN 840 850 860 870 880 890 810 820 830 840 850 860 pF1KA0 YWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAYSCFSHLMKRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAYSCFSHLMKRM 900 910 920 930 940 950 870 880 890 900 910 920 pF1KA0 SQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYED 960 970 980 990 1000 1010 930 940 950 960 970 980 pF1KA0 VFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQE 1020 1030 1040 1050 1060 1070 990 1000 pF1KA0 ILRIARDLVHKVQMLIENK :::::::::::: XP_011 ILRIARDLVHKVLP 1080 1090 >-- initn: 316 init1: 287 opt: 287 Z-score: 253.5 bits: 58.5 E(85289): 2.2e-07 Smith-Waterman score: 287; 97.8% identity (100.0% similar) in 46 aa overlap (1-46:1-46) 10 20 30 40 50 60 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA ::::::::::::::::::::::::::::::::::::::::::::.: XP_011 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCAADPHQGLTRCQTPFT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP XP_011 VQGNGSDKMDRVSAAGAYILLGRQTGNKCASAVEACLLHQLRRRAAGFLRSDKMAALFTK 70 80 90 100 110 120 >>XP_016880965 (OMIM: 611418) PREDICTED: small G protein (785 aa) initn: 3782 init1: 3782 opt: 3795 Z-score: 3316.3 bits: 624.8 E(85289): 5.6e-178 Smith-Waterman score: 4787; 92.8% identity (93.3% similar) in 764 aa overlap (273-991:1-762) 250 260 270 280 290 300 pF1KA0 ARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMNGT :::::::::::::::::::::::::::::: XP_016 MEAVPGYLSLHQSAESLTLKWTPNQLMNGT 10 20 30 310 320 330 340 350 360 pF1KA0 LGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHLLS 40 50 60 70 80 90 370 380 390 400 410 420 pF1KA0 FLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRIIY 100 110 120 130 140 150 430 pF1KA0 PGHRHEH---------------------------------------------NAGDMIEM ::::::: .::::::: XP_016 PGHRHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMIEM 160 170 180 190 200 210 440 450 460 470 480 490 pF1KA0 QGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQIVS 220 230 240 250 260 270 500 510 520 530 540 550 pF1KA0 RAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKELE 280 290 300 310 320 330 560 570 580 590 600 610 pF1KA0 LLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEVVV 340 350 360 370 380 390 620 630 640 650 660 670 pF1KA0 RQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSRPK 400 410 420 430 440 450 680 690 700 710 720 730 pF1KA0 PEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEEDGG 460 470 480 490 500 510 740 750 760 770 780 790 pF1KA0 GEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLHRI 520 530 540 550 560 570 800 810 820 830 840 850 pF1KA0 DKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAY 580 590 600 610 620 630 860 870 880 890 900 910 pF1KA0 SCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLL 640 650 660 670 680 690 920 930 940 950 960 970 pF1KA0 DFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFN 700 710 720 730 740 750 980 990 1000 pF1KA0 ERAEHHDAQEILRIARDLVHKVQMLIENK : : . :..: : XP_016 --ALHVSPQNVLSITMPRRSCGLPGTSSTRYFPENHV 760 770 780 >>XP_011522408 (OMIM: 611418) PREDICTED: small G protein (1057 aa) initn: 3782 init1: 3782 opt: 3795 Z-score: 3314.6 bits: 624.9 E(85289): 6.9e-178 Smith-Waterman score: 6513; 94.6% identity (95.0% similar) in 1023 aa overlap (14-991:14-1034) 10 20 30 40 50 60 pF1KA0 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI 370 380 390 400 410 420 430 pF1KA0 IYPGHRHEH---------------------------------------------NAGDMI ::::::::: .::::: XP_011 IYPGHRHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMI 430 440 450 460 470 480 440 450 460 470 480 490 pF1KA0 EMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI 490 500 510 520 530 540 500 510 520 530 540 550 pF1KA0 VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKE 550 560 570 580 590 600 560 570 580 590 600 610 pF1KA0 LELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEV 610 620 630 640 650 660 620 630 640 650 660 670 pF1KA0 VVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSR 670 680 690 700 710 720 680 690 700 710 720 730 pF1KA0 PKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEED 730 740 750 760 770 780 740 750 760 770 780 790 pF1KA0 GGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGEEGSSGPGPAAHTLREPQDPSQEKPQAGELEAGEELAAVCAAAYTIELLDTVALNLH 790 800 810 820 830 840 800 810 820 830 840 850 pF1KA0 RIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQL 850 860 870 880 890 900 860 870 880 890 900 910 pF1KA0 AYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWF 910 920 930 940 950 960 920 930 940 950 960 970 pF1KA0 LLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKF 970 980 990 1000 1010 1020 980 990 1000 pF1KA0 FNERAEHHDAQEILRIARDLVHKVQMLIENK :: : : . :..: : XP_011 FN--ALHVSPQNVLSITMPRRSCGLPGTSSTRYFPENHV 1030 1040 1050 1006 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:34:02 2016 done: Thu Nov 3 09:34:04 2016 Total Scan time: 16.210 Total Display time: 0.420 Function used was FASTA [36.3.4 Apr, 2011]