Result of FASTA (omim) for
pF1KA0400
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0400, 1006 aa
1>>>pF1KA0400 1006 - 1006 aa - 1006 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.6363+/-0.000541; mu= -30.3218+/- 0.034
mean_var=723.5385+/-152.161, 0's: 0 Z-trim(122.4): 86 B-trim: 2143 in 1/60
Lambda= 0.047681
statistics sampled from 40432 (40520) to 40432 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.475), width: 16
Scan time: 16.220
The best scores are: opt bits E(85289)
NP_003878 (OMIM: 603817) arf-GAP with SH3 domain, (1006) 6734 479.3 4.6e-134
XP_006711961 (OMIM: 603817) PREDICTED: arf-GAP wit (1009) 6718 478.2 1e-133
XP_011508706 (OMIM: 603817) PREDICTED: arf-GAP wit (1017) 6470 461.1 1.4e-128
XP_006711964 (OMIM: 603817) PREDICTED: arf-GAP wit ( 970) 6458 460.3 2.3e-128
XP_011508708 (OMIM: 603817) PREDICTED: arf-GAP wit ( 978) 6458 460.3 2.4e-128
XP_011508705 (OMIM: 603817) PREDICTED: arf-GAP wit (1020) 6454 460.0 2.9e-128
XP_011508711 (OMIM: 603817) PREDICTED: arf-GAP wit ( 891) 5961 426.0 4.3e-118
XP_011508707 (OMIM: 603817) PREDICTED: arf-GAP wit ( 995) 5819 416.3 4.1e-115
NP_001128663 (OMIM: 603817) arf-GAP with SH3 domai ( 961) 5343 383.6 2.9e-105
XP_006711965 (OMIM: 603817) PREDICTED: arf-GAP wit ( 964) 5327 382.5 6.1e-105
XP_011508709 (OMIM: 603817) PREDICTED: arf-GAP wit ( 975) 5063 364.3 1.8e-99
XP_011508710 (OMIM: 603817) PREDICTED: arf-GAP wit ( 959) 5006 360.4 2.7e-98
NP_001234925 (OMIM: 605953) arf-GAP with SH3 domai (1122) 3494 256.4 6.3e-67
NP_060952 (OMIM: 605953) arf-GAP with SH3 domain, (1129) 3494 256.4 6.3e-67
XP_006716629 (OMIM: 605953) PREDICTED: arf-GAP wit (1075) 3484 255.7 9.7e-67
XP_016868958 (OMIM: 605953) PREDICTED: arf-GAP wit (1072) 3470 254.7 1.9e-66
XP_011515355 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 3459 254.0 3.3e-66
XP_006716627 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 3459 254.0 3.3e-66
XP_006716626 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 3459 254.0 3.3e-66
XP_011515354 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 3459 254.0 3.3e-66
XP_005250982 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 3459 254.0 3.3e-66
XP_016868957 (OMIM: 605953) PREDICTED: arf-GAP wit (1073) 3263 240.5 3.7e-62
XP_016868956 (OMIM: 605953) PREDICTED: arf-GAP wit (1087) 3262 240.4 3.9e-62
XP_006716628 (OMIM: 605953) PREDICTED: arf-GAP wit (1076) 3256 240.0 5.1e-62
XP_016857174 (OMIM: 616594) PREDICTED: arf-GAP wit ( 924) 2660 199.0 1e-49
XP_011540057 (OMIM: 616594) PREDICTED: arf-GAP wit ( 926) 2648 198.2 1.8e-49
NP_060177 (OMIM: 616594) arf-GAP with SH3 domain, ( 903) 2600 194.8 1.7e-48
XP_016857175 (OMIM: 616594) PREDICTED: arf-GAP wit ( 905) 2588 194.0 3e-48
XP_016857176 (OMIM: 616594) PREDICTED: arf-GAP wit ( 883) 2500 188.0 2e-46
XP_016857177 (OMIM: 616594) PREDICTED: arf-GAP wit ( 793) 2226 169.1 8.6e-41
XP_016857178 (OMIM: 616594) PREDICTED: arf-GAP wit ( 774) 2154 164.1 2.6e-39
NP_001137250 (OMIM: 616594) arf-GAP with SH3 domai ( 894) 2071 158.5 1.5e-37
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 505 50.7 3.7e-05
XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 505 50.7 3.8e-05
XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 460 47.6 0.00032
XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 460 47.6 0.00033
XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 433 45.7 0.0011
XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 433 45.8 0.0012
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462) 409 43.9 0.0024
XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527) 409 44.0 0.0026
NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580) 409 44.0 0.0028
XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580) 409 44.0 0.0028
XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565) 405 43.7 0.0034
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 410 44.2 0.0034
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 410 44.2 0.0034
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 410 44.2 0.0034
XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630) 405 43.7 0.0037
XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683) 405 43.8 0.0039
NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK ( 911) 405 43.9 0.0049
XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882) 390 42.8 0.0098
>>NP_003878 (OMIM: 603817) arf-GAP with SH3 domain, ANK (1006 aa)
initn: 6734 init1: 6734 opt: 6734 Z-score: 2527.8 bits: 479.3 E(85289): 4.6e-134
Smith-Waterman score: 6734; 100.0% identity (100.0% similar) in 1006 aa overlap (1-1006:1-1006)
10 20 30 40 50 60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
910 920 930 940 950 960
970 980 990 1000
pF1KA0 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
970 980 990 1000
>>XP_006711961 (OMIM: 603817) PREDICTED: arf-GAP with SH (1009 aa)
initn: 4929 init1: 4929 opt: 6718 Z-score: 2521.8 bits: 478.2 E(85289): 1e-133
Smith-Waterman score: 6718; 99.7% identity (99.7% similar) in 1009 aa overlap (1-1006:1-1009)
10 20 30 40 50 60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
190 200 210 220 230 240
250 260 270 280 290
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQ
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_006 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 APSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVT
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 STNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
910 920 930 940 950 960
960 970 980 990 1000
pF1KA0 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
970 980 990 1000
>>XP_011508706 (OMIM: 603817) PREDICTED: arf-GAP with SH (1017 aa)
initn: 6470 init1: 6470 opt: 6470 Z-score: 2429.6 bits: 461.1 E(85289): 1.4e-128
Smith-Waterman score: 6702; 98.9% identity (98.9% similar) in 1017 aa overlap (1-1006:1-1017)
10 20 30 40
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEE-----------ALDVDRM
:::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEVRRPARRLRPQALDVDRM
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 STAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 NLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDN
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 TGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVH
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 YSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 YIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETAL
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 HLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEI
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 ANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 QPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSG
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 SPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHP
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 PLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQ
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 KKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRV
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 KALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
970 980 990 1000 1010
>>XP_006711964 (OMIM: 603817) PREDICTED: arf-GAP with SH (970 aa)
initn: 4929 init1: 4929 opt: 6458 Z-score: 2425.4 bits: 460.3 E(85289): 2.3e-128
Smith-Waterman score: 6458; 99.7% identity (99.7% similar) in 968 aa overlap (42-1006:3-970)
20 30 40 50 60 70
pF1KA0 AETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVEN
::::::::::::::::::::::::::::::
XP_006 MLEALDVDRMVLYKMKKSVKAINSSGLAHVEN
10 20 30
80 90 100 110 120 130
pF1KA0 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA0 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA0 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
160 170 180 190 200 210
260 270 280 290 300
pF1KA0 LHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQPQGNKEHGTER
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_006 LHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQPQGNKEHGTER
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
880 890 900 910 920 930
970 980 990 1000
pF1KA0 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
::::::::::::::::::::::::::::::::::::::
XP_006 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
940 950 960 970
>>XP_011508708 (OMIM: 603817) PREDICTED: arf-GAP with SH (978 aa)
initn: 4929 init1: 4929 opt: 6458 Z-score: 2425.4 bits: 460.3 E(85289): 2.4e-128
Smith-Waterman score: 6458; 99.7% identity (99.7% similar) in 968 aa overlap (42-1006:11-978)
20 30 40 50 60 70
pF1KA0 AETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVEN
::::::::::::::::::::::::::::::
XP_011 MISVPIQKSPEALDVDRMVLYKMKKSVKAINSSGLAHVEN
10 20 30 40
80 90 100 110 120 130
pF1KA0 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KA0 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKER
110 120 130 140 150 160
200 210 220 230 240 250
pF1KA0 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTD
170 180 190 200 210 220
260 270 280 290 300
pF1KA0 LHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQPQGNKEHGTER
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 LHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQPQGNKEHGTER
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQ
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLL
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLH
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLV
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEH
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLP
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQP
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEG
890 900 910 920 930 940
970 980 990 1000
pF1KA0 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
::::::::::::::::::::::::::::::::::::::
XP_011 DVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
950 960 970
>>XP_011508705 (OMIM: 603817) PREDICTED: arf-GAP with SH (1020 aa)
initn: 5181 init1: 4929 opt: 6454 Z-score: 2423.6 bits: 460.0 E(85289): 2.9e-128
Smith-Waterman score: 6686; 98.6% identity (98.6% similar) in 1020 aa overlap (1-1006:1-1020)
10 20 30 40
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEE-----------ALDVDRM
:::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEVRRPARRLRPQALDVDRM
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA0 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQ
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA0 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA0 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA0 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA0 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA0 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA0 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA0 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA0 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
970 980 990 1000 1010 1020
>>XP_011508711 (OMIM: 603817) PREDICTED: arf-GAP with SH (891 aa)
initn: 4929 init1: 4929 opt: 5961 Z-score: 2241.2 bits: 426.0 E(85289): 4.3e-118
Smith-Waterman score: 5961; 99.7% identity (99.7% similar) in 891 aa overlap (119-1006:1-891)
90 100 110 120 130 140
pF1KA0 RDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDK
::::::::::::::::::::::::::::::
XP_011 MNNIISFPLDSLLKGDLKGVKGDLKKPFDK
10 20 30
150 160 170 180 190 200
pF1KA0 AWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KA0 KIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQ
100 110 120 130 140 150
270 280 290 300 310 320
pF1KA0 LRDILKSALQVEQKE---DSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQK
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDILKSALQVEQKESRRDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQK
160 170 180 190 200 210
330 340 350 360 370 380
pF1KA0 RKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQEC
220 230 240 250 260 270
390 400 410 420 430 440
pF1KA0 QIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPT
280 290 300 310 320 330
450 460 470 480 490 500
pF1KA0 WLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCL
340 350 360 370 380 390
510 520 530 540 550 560
pF1KA0 PAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQA
400 410 420 430 440 450
570 580 590 600 610 620
pF1KA0 YADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTAL
460 470 480 490 500 510
630 640 650 660 670 680
pF1KA0 HYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHV
520 530 540 550 560 570
690 700 710 720 730 740
pF1KA0 HVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANL
580 590 600 610 620 630
750 760 770 780 790 800
pF1KA0 AKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLW
640 650 660 670 680 690
810 820 830 840 850 860
pF1KA0 KTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSK
700 710 720 730 740 750
870 880 890 900 910 920
pF1KA0 PAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSN
760 770 780 790 800 810
930 940 950 960 970 980
pF1KA0 AMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGH
820 830 840 850 860 870
990 1000
pF1KA0 IDGDPGRKGAFPVSFVHFIAD
:::::::::::::::::::::
XP_011 IDGDPGRKGAFPVSFVHFIAD
880 890
>>XP_011508707 (OMIM: 603817) PREDICTED: arf-GAP with SH (995 aa)
initn: 5389 init1: 4929 opt: 5819 Z-score: 2187.7 bits: 416.3 E(85289): 4.1e-115
Smith-Waterman score: 6465; 96.2% identity (96.2% similar) in 1020 aa overlap (1-1006:1-995)
10 20 30 40
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEE-----------ALDVDRM
:::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEVRRPARRLRPQALDVDRM
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELT
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 ALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAK
:::::: :::::::::::::::::::::::::::::
XP_011 ALFKNL-------------------------DLKKPFDKAWKDYETKITKIEKEKKEHAK
130 140 150
170 180 190 200 210 220
pF1KA0 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCN
160 170 180 190 200 210
230 240 250 260 270 280
pF1KA0 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 FFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQ
220 230 240 250 260 270
290 300 310 320 330 340
pF1KA0 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPP
280 290 300 310 320 330
350 360 370 380 390 400
pF1KA0 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKG
340 350 360 370 380 390
410 420 430 440 450 460
pF1KA0 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHREL
400 410 420 430 440 450
470 480 490 500 510 520
pF1KA0 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYI
460 470 480 490 500 510
530 540 550 560 570 580
pF1KA0 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAKYIERRYARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDE
520 530 540 550 560 570
590 600 610 620 630 640
pF1KA0 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKAS
580 590 600 610 620 630
650 660 670 680 690 700
pF1KA0 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMD
640 650 660 670 680 690
710 720 730 740 750 760
pF1KA0 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLQPSPNRREDRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGAL
700 710 720 730 740 750
770 780 790 800 810 820
pF1KA0 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPA
760 770 780 790 800 810
830 840 850 860 870 880
pF1KA0 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR
820 830 840 850 860 870
890 900 910 920 930 940
pF1KA0 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP
880 890 900 910 920 930
950 960 970 980 990 1000
pF1KA0 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
940 950 960 970 980 990
>>NP_001128663 (OMIM: 603817) arf-GAP with SH3 domain, A (961 aa)
initn: 5286 init1: 5286 opt: 5343 Z-score: 2010.9 bits: 383.6 E(85289): 2.9e-105
Smith-Waterman score: 6332; 95.4% identity (95.5% similar) in 1006 aa overlap (1-1006:1-961)
10 20 30 40 50 60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVTSTN
:::::::::::::: .
NP_001 TTSAPPLPPRNVGK---------------------------------------------D
790
850 860 870 880 890 900
pF1KA0 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKST
800 810 820 830 840 850
910 920 930 940 950 960
pF1KA0 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNP
860 870 880 890 900 910
970 980 990 1000
pF1KA0 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
920 930 940 950 960
>>XP_006711965 (OMIM: 603817) PREDICTED: arf-GAP with SH (964 aa)
initn: 5339 init1: 3481 opt: 5327 Z-score: 2005.0 bits: 382.5 E(85289): 6.1e-105
Smith-Waterman score: 6316; 95.1% identity (95.2% similar) in 1009 aa overlap (1-1006:1-964)
10 20 30 40 50 60
pF1KA0 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVES
190 200 210 220 230 240
250 260 270 280 290
pF1KA0 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKE---DSQIRQSTAYSLHQ
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_006 LKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKESRRDSQIRQSTAYSLHQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYAR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVD
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRRE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRPISFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 APSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHPPLPPLRVT
:::::::::::::::::
XP_006 APSTTSAPPLPPRNVGK-------------------------------------------
790
840 850 860 870 880 890
pF1KA0 STNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 --DPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGAD
800 810 820 830 840 850
900 910 920 930 940 950
pF1KA0 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVA
860 870 880 890 900 910
960 970 980 990 1000
pF1KA0 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGAFPVSFVHFIAD
920 930 940 950 960
1006 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:39:32 2016 done: Fri Nov 4 00:39:34 2016
Total Scan time: 16.220 Total Display time: 0.430
Function used was FASTA [36.3.4 Apr, 2011]