FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0405, 660 aa 1>>>pF1KA0405 660 - 660 aa - 660 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7482+/-0.00046; mu= 4.4055+/- 0.029 mean_var=215.8299+/-43.442, 0's: 0 Z-trim(117.6): 344 B-trim: 1373 in 1/54 Lambda= 0.087301 statistics sampled from 29340 (29714) to 29340 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.348), width: 16 Scan time: 9.370 The best scores are: opt bits E(85289) XP_016876624 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 XP_011534913 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 XP_016876623 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 NP_001333075 (OMIM: 604807) leucine-rich repeat tr ( 660) 4435 572.0 2.5e-162 XP_016876621 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 NP_001333074 (OMIM: 604807) leucine-rich repeat tr ( 660) 4435 572.0 2.5e-162 NP_037363 (OMIM: 604807) leucine-rich repeat trans ( 660) 4435 572.0 2.5e-162 NP_001333073 (OMIM: 604807) leucine-rich repeat tr ( 660) 4435 572.0 2.5e-162 XP_016876618 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 NP_001333072 (OMIM: 604807) leucine-rich repeat tr ( 660) 4435 572.0 2.5e-162 XP_016876619 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 XP_005267547 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 XP_016876620 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 XP_016876622 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 4435 572.0 2.5e-162 XP_005273918 (OMIM: 604806) PREDICTED: leucine-ric ( 674) 1835 244.5 9.5e-64 NP_037412 (OMIM: 604806) leucine-rich repeat trans ( 674) 1835 244.5 9.5e-64 XP_011543185 (OMIM: 604806) PREDICTED: leucine-ric ( 674) 1835 244.5 9.5e-64 NP_037413 (OMIM: 604808,615271) leucine-rich repea ( 649) 1684 225.5 4.9e-58 XP_011527506 (OMIM: 604808,615271) PREDICTED: leuc ( 649) 1684 225.5 4.9e-58 NP_938205 (OMIM: 604808,615271) leucine-rich repea ( 649) 1684 225.5 4.9e-58 XP_005260739 (OMIM: 604808,615271) PREDICTED: leuc ( 649) 1684 225.5 4.9e-58 XP_011527507 (OMIM: 604808,615271) PREDICTED: leuc ( 649) 1684 225.5 4.9e-58 NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545) 485 74.4 1.2e-12 XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545) 485 74.4 1.2e-12 NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545) 485 74.4 1.2e-12 XP_011538979 (OMIM: 608661) PREDICTED: podocan iso ( 402) 427 67.0 1.5e-10 XP_005270514 (OMIM: 608661) PREDICTED: podocan iso ( 613) 427 67.1 2.1e-10 NP_001186009 (OMIM: 608661) podocan isoform 2 [Hom ( 642) 427 67.1 2.2e-10 NP_001186010 (OMIM: 608661) podocan isoform 2 [Hom ( 642) 427 67.1 2.2e-10 XP_016855783 (OMIM: 608661) PREDICTED: podocan iso ( 652) 427 67.2 2.2e-10 NP_714914 (OMIM: 608661) podocan isoform 1 [Homo s ( 661) 427 67.2 2.3e-10 NP_821079 (OMIM: 610869) leucine-rich repeat trans ( 581) 414 65.5 6.4e-10 XP_011518541 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_011518542 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873565 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 NP_001245348 (OMIM: 608817) leucine-rich repeat-co ( 640) 406 64.5 1.4e-09 NP_065980 (OMIM: 608817) leucine-rich repeat-conta ( 640) 406 64.5 1.4e-09 XP_016873564 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_011518544 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873559 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_011518546 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_011518543 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_011518545 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873563 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873568 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_011518540 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873567 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873560 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873566 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 XP_016873562 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 406 64.5 1.4e-09 >>XP_016876624 (OMIM: 604807) PREDICTED: leucine-rich re (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>XP_011534913 (OMIM: 604807) PREDICTED: leucine-rich re (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>XP_016876623 (OMIM: 604807) PREDICTED: leucine-rich re (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>NP_001333075 (OMIM: 604807) leucine-rich repeat transm (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>XP_016876621 (OMIM: 604807) PREDICTED: leucine-rich re (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>NP_001333074 (OMIM: 604807) leucine-rich repeat transm (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>NP_037363 (OMIM: 604807) leucine-rich repeat transmemb (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>NP_001333073 (OMIM: 604807) leucine-rich repeat transm (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>XP_016876618 (OMIM: 604807) PREDICTED: leucine-rich re (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 >>NP_001333072 (OMIM: 604807) leucine-rich repeat transm (660 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 3035.4 bits: 572.0 E(85289): 2.5e-162 Smith-Waterman score: 4435; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660) 10 20 30 40 50 60 pF1KA0 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLQTTKWPSHGAFFLKSWLIISLGLYSQVSKLLACPSVCRCDRNFVYCNERSLTSVPLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPTTSKLPTIPDWDGRERVTPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLEPRSTYRICLVPLDAFNYRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGSP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSIL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT 610 620 630 640 650 660 660 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:48:56 2016 done: Wed Nov 2 18:48:57 2016 Total Scan time: 9.370 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]