FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0407, 2135 aa 1>>>pF1KA0407 2135 - 2135 aa - 2135 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.3411+/-0.000567; mu= -23.2329+/- 0.035 mean_var=633.6914+/-132.371, 0's: 0 Z-trim(120.0): 69 B-trim: 33 in 1/57 Lambda= 0.050949 statistics sampled from 34528 (34597) to 34528 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.406), width: 16 Scan time: 27.140 The best scores are: opt bits E(85289) NP_001123554 (OMIM: 601053) plexin-B1 precursor [H (2135) 14586 1089.4 0 XP_016862120 (OMIM: 601053) PREDICTED: plexin-B1 i (2135) 14586 1089.4 0 NP_002664 (OMIM: 601053) plexin-B1 precursor [Homo (2135) 14586 1089.4 0 XP_011532138 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 14574 1088.6 0 XP_011532139 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 14574 1088.6 0 XP_011532136 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 14574 1088.6 0 XP_011532137 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 14574 1088.6 0 XP_016862119 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 14574 1088.6 0 XP_011532135 (OMIM: 601053) PREDICTED: plexin-B1 i (2136) 14574 1088.6 0 NP_005384 (OMIM: 300214) plexin-B3 isoform 1 precu (1909) 3067 242.7 3e-62 NP_001156729 (OMIM: 300214) plexin-B3 isoform 2 [H (1932) 3067 242.7 3e-62 XP_006724476 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 1671 140.1 2.2e-31 XP_005261966 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 1671 140.1 2.2e-31 NP_036533 (OMIM: 604293) plexin-B2 precursor [Homo (1838) 1671 140.1 2.2e-31 XP_016884193 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 1671 140.1 2.2e-31 XP_005261967 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 1671 140.1 2.2e-31 XP_005261968 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 1671 140.1 2.2e-31 XP_016884192 (OMIM: 604293) PREDICTED: plexin-B2 i (1838) 1671 140.1 2.2e-31 XP_011528984 (OMIM: 604293) PREDICTED: plexin-B2 i (1901) 1671 140.1 2.3e-31 XP_005273222 (OMIM: 601054) PREDICTED: plexin-A2 i (1823) 1243 108.6 6.6e-22 NP_115618 (OMIM: 601055) plexin-A1 precursor [Homo (1896) 1243 108.6 6.8e-22 XP_011511210 (OMIM: 601055) PREDICTED: plexin-A1 i (1914) 1243 108.6 6.9e-22 XP_011511211 (OMIM: 601055) PREDICTED: plexin-A1 i (1914) 1243 108.6 6.9e-22 XP_011529485 (OMIM: 300022) PREDICTED: plexin-A3 i (1684) 1178 103.8 1.7e-20 XP_005274763 (OMIM: 300022) PREDICTED: plexin-A3 i (1789) 1178 103.8 1.8e-20 XP_006724892 (OMIM: 300022) PREDICTED: plexin-A3 i (1841) 1178 103.9 1.8e-20 XP_005274762 (OMIM: 300022) PREDICTED: plexin-A3 i (1853) 1178 103.9 1.8e-20 NP_059984 (OMIM: 300022) plexin-A3 precursor [Homo (1871) 1178 103.9 1.8e-20 XP_011510894 (OMIM: 604282) PREDICTED: plexin-D1 i ( 981) 1144 101.2 6.3e-20 XP_011510891 (OMIM: 604282) PREDICTED: plexin-D1 i (1795) 1144 101.4 1e-19 NP_055918 (OMIM: 604282) plexin-D1 precursor [Homo (1925) 1145 101.4 1e-19 XP_011510890 (OMIM: 604282) PREDICTED: plexin-D1 i (1894) 1064 95.5 6.2e-18 NP_079455 (OMIM: 601054) plexin-A2 precursor [Homo (1894) 902 83.6 2.4e-14 XP_016868268 (OMIM: 604280) PREDICTED: plexin-A4 i (1827) 892 82.8 3.9e-14 XP_006716234 (OMIM: 604280) PREDICTED: plexin-A4 i (1894) 892 82.8 4e-14 NP_065962 (OMIM: 604280) plexin-A4 isoform 1 precu (1894) 892 82.8 4e-14 XP_005250743 (OMIM: 604280) PREDICTED: plexin-A4 i (1894) 892 82.8 4e-14 XP_005273221 (OMIM: 601054) PREDICTED: plexin-A2 i (1974) 773 74.1 1.8e-11 XP_016874161 (OMIM: 604259) PREDICTED: plexin-C1 i (1315) 749 72.2 4.4e-11 XP_016874160 (OMIM: 604259) PREDICTED: plexin-C1 i (1323) 730 70.8 1.2e-10 XP_011536032 (OMIM: 604259) PREDICTED: plexin-C1 i (1322) 726 70.5 1.4e-10 XP_006719249 (OMIM: 604259) PREDICTED: plexin-C1 i (1555) 696 68.4 7.4e-10 NP_005752 (OMIM: 604259) plexin-C1 precursor [Homo (1568) 696 68.4 7.4e-10 XP_011510892 (OMIM: 604282) PREDICTED: plexin-D1 i (1467) 625 63.1 2.6e-08 NP_001311330 (OMIM: 114550,164860,605074,607278,61 ( 934) 420 47.9 0.00063 XP_006716053 (OMIM: 114550,164860,605074,607278,61 ( 960) 420 47.9 0.00065 NP_001311331 (OMIM: 114550,164860,605074,607278,61 ( 960) 420 47.9 0.00065 NP_000236 (OMIM: 114550,164860,605074,607278,61670 (1390) 420 48.1 0.00087 XP_011514525 (OMIM: 114550,164860,605074,607278,61 (1409) 420 48.1 0.00088 >>NP_001123554 (OMIM: 601053) plexin-B1 precursor [Homo (2135 aa) initn: 14586 init1: 14586 opt: 14586 Z-score: 5813.8 bits: 1089.4 E(85289): 0 Smith-Waterman score: 14586; 100.0% identity (100.0% similar) in 2135 aa overlap (1-2135:1-2135) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2050 2060 2070 2080 2090 2100 2110 2120 2130 pF1KA0 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL ::::::::::::::::::::::::::::::::::: NP_001 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_016862120 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2135 aa) initn: 14586 init1: 14586 opt: 14586 Z-score: 5813.8 bits: 1089.4 E(85289): 0 Smith-Waterman score: 14586; 100.0% identity (100.0% similar) in 2135 aa overlap (1-2135:1-2135) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2050 2060 2070 2080 2090 2100 2110 2120 2130 pF1KA0 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL ::::::::::::::::::::::::::::::::::: XP_016 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>NP_002664 (OMIM: 601053) plexin-B1 precursor [Homo sap (2135 aa) initn: 14586 init1: 14586 opt: 14586 Z-score: 5813.8 bits: 1089.4 E(85289): 0 Smith-Waterman score: 14586; 100.0% identity (100.0% similar) in 2135 aa overlap (1-2135:1-2135) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2050 2060 2070 2080 2090 2100 2110 2120 2130 pF1KA0 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL ::::::::::::::::::::::::::::::::::: NP_002 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_011532138 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2136 aa) initn: 12618 init1: 12618 opt: 14574 Z-score: 5809.0 bits: 1088.6 E(85289): 0 Smith-Waterman score: 14574; 100.0% identity (100.0% similar) in 2136 aa overlap (1-2135:1-2136) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYK-VPDGATVALVPCLTKHVLR :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKQVPDGATVALVPCLTKHVLR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 pF1KA0 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL :::::::::::::::::::::::::::::::::::: XP_011 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_011532139 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2136 aa) initn: 12618 init1: 12618 opt: 14574 Z-score: 5809.0 bits: 1088.6 E(85289): 0 Smith-Waterman score: 14574; 100.0% identity (100.0% similar) in 2136 aa overlap (1-2135:1-2136) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYK-VPDGATVALVPCLTKHVLR :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKQVPDGATVALVPCLTKHVLR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 pF1KA0 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL :::::::::::::::::::::::::::::::::::: XP_011 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_011532136 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2136 aa) initn: 12618 init1: 12618 opt: 14574 Z-score: 5809.0 bits: 1088.6 E(85289): 0 Smith-Waterman score: 14574; 100.0% identity (100.0% similar) in 2136 aa overlap (1-2135:1-2136) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYK-VPDGATVALVPCLTKHVLR :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKQVPDGATVALVPCLTKHVLR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 pF1KA0 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL :::::::::::::::::::::::::::::::::::: XP_011 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_011532137 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2136 aa) initn: 12618 init1: 12618 opt: 14574 Z-score: 5809.0 bits: 1088.6 E(85289): 0 Smith-Waterman score: 14574; 100.0% identity (100.0% similar) in 2136 aa overlap (1-2135:1-2136) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYK-VPDGATVALVPCLTKHVLR :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKQVPDGATVALVPCLTKHVLR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 pF1KA0 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL :::::::::::::::::::::::::::::::::::: XP_011 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_016862119 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2136 aa) initn: 12618 init1: 12618 opt: 14574 Z-score: 5809.0 bits: 1088.6 E(85289): 0 Smith-Waterman score: 14574; 100.0% identity (100.0% similar) in 2136 aa overlap (1-2135:1-2136) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYK-VPDGATVALVPCLTKHVLR :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKQVPDGATVALVPCLTKHVLR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 pF1KA0 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL :::::::::::::::::::::::::::::::::::: XP_016 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>XP_011532135 (OMIM: 601053) PREDICTED: plexin-B1 isofo (2136 aa) initn: 12618 init1: 12618 opt: 14574 Z-score: 5809.0 bits: 1088.6 E(85289): 0 Smith-Waterman score: 14574; 100.0% identity (100.0% similar) in 2136 aa overlap (1-2135:1-2136) 10 20 30 40 50 60 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 pF1KA0 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYK-VPDGATVALVPCLTKHVLR :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKQVPDGATVALVPCLTKHVLR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KA0 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KA0 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTN 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KA0 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYA 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KA0 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYY 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 pF1KA0 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL :::::::::::::::::::::::::::::::::::: XP_011 DQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2110 2120 2130 >>NP_005384 (OMIM: 300214) plexin-B3 isoform 1 precursor (1909 aa) initn: 4747 init1: 1242 opt: 3067 Z-score: 1238.6 bits: 242.7 E(85289): 3e-62 Smith-Waterman score: 5826; 47.0% identity (66.1% similar) in 2164 aa overlap (2-2135:23-1909) 10 20 30 pF1KA0 MPALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQ : .: :: : :. ::: :. :. .: :. NP_005 MCHAAQETPLLHHFMAPVMARWPPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLN 10 20 30 40 50 40 50 60 70 80 90 pF1KA0 HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNN ::: : ::::.::.: :::::: :::::.. ::::.:: ::.: : :::::: :.: NP_005 HLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDN 60 70 80 90 100 110 100 110 120 130 140 150 pF1KA0 PNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVG ::::::: : ::.::.:.::::: ::::.. ..: . : ::: :.:::: :.:.::: NP_005 ANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVG 120 130 140 150 160 170 160 170 180 190 200 210 pF1KA0 LVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEY ::. : :. ::.:.:: ... ...:.::.. : : .: :: : ..:.:: .:.: NP_005 LVVP-LPGRDLLLVARGLAGK-LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDY 180 190 200 210 220 230 220 230 240 250 260 270 pF1KA0 SHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYG .. .:.::: . ::::.: :: .::.. .:.::.:::: : . :::::.::::.: : NP_005 NNSYVGAFADARSAYFVFRRRGARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QG 240 250 260 270 280 280 290 300 310 320 330 pF1KA0 LIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLA ::::: .: . .:...: ::: :. .::::::. :. NP_005 LIQAAFLAPG-------TLLGVF--------------AAGPRGTQAALCAFPMVELGASM 290 300 310 320 340 350 360 370 380 390 pF1KA0 NRTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLE ...: ::: ::. .:.: : .:: :.: :. ::.:. ..::::..:::::.:.: ::: NP_005 EQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLE 330 340 350 360 370 380 400 410 420 430 440 450 pF1KA0 ATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSA . :.:. : ..:::. . ::: ::::::.::::..:.: ::.:. : .:.. ::: NP_005 VQPLLKL-GQPVSAVAALQADGHMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSA 390 400 410 420 430 440 460 470 480 490 500 510 pF1KA0 VSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRS .: :: .:.. ::::.: . ..:::.: : :::::: .:: :::::: :::.:.. NP_005 ISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKG 450 460 470 480 490 500 520 530 540 550 560 570 pF1KA0 ECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHF .:.:. .:::::.. . ::.. .. :.. :.: .: :::: :: : : . : : NP_005 QCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAF 510 520 530 540 550 560 580 590 600 610 620 630 pF1KA0 GEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAV :...: : . : : : .: ...:. : :.:.:.: . : : :..: :..::::: :: NP_005 GDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAV 570 580 590 600 610 620 640 650 660 670 680 690 pF1KA0 TELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSP :. .: :.:::.: : :.:: . :.. : NP_005 QALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHC-------------------------- 630 640 650 700 710 720 730 740 750 pF1KA0 SPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTG NP_005 ------------------------------------------------------------ 760 770 780 790 800 810 pF1KA0 SPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHP :: NP_005 -------------------------------PE--------------------------- 660 820 830 840 850 860 870 pF1KA0 TVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGD :. .:.. . NP_005 ---------------------------------------------GERTIYSAQEV---- 670 880 890 900 910 920 930 pF1KA0 GDSAELEGPPAPLILPSSLDYQYDTPGLWELEEATLGASSCPCVESVQGSTLMPVHVERE : : :: .:: ::.. : :.:: : . NP_005 -------------------DIQVRGPG------------ACPQVEGLAGPHLVPVGWESH 680 690 700 940 950 960 970 980 990 pF1KA0 IRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVTCQQHQLSYEALQ . : :::. :. :.. .: .:: : . : .: : :. . :: ::. : NP_005 LALRVRNLQHFRGLPASFHCWLELPGELRGLPATLE-ETAGDSGL-IHCQAHQFYPSMSQ 710 720 730 740 750 1000 1010 1020 1030 1040 1050 pF1KA0 PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVWCEGERPRCV :: : ... .. :.:....:.:.::::..:: :::.::.: . ::.:: .: : NP_005 RELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPACR 760 770 780 790 800 810 1060 1070 1080 1090 1100 1110 pF1KA0 TREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVP : . :: :::: : .::::::: .:: .:: :::::. :: :.::. : NP_005 YGPLCPPG-AVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRP 820 830 840 850 860 870 1120 1130 1140 1150 1160 1170 pF1KA0 CAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPKVHSIFPARG : . . :..:. .::.:. . . ..: . : . .. :.: . :.:::: . :. : : NP_005 CNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWG 880 890 900 910 920 930 1180 1190 1200 1210 1220 1230 pF1KA0 PRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAV :.::::.::. :..: :: . . :: ::: .: : . :.: :. .:. : : NP_005 PQAGGTQLTIRGQHLQTG--GNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLV 940 950 960 970 980 990 1240 1250 1260 1270 1280 pF1KA0 WFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRV----- :: ..: : . :.:: .:....: :. :: .::: : ::: .::::: : . : NP_005 VFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEAD 1000 1010 1020 1030 1040 1050 1290 1300 1310 1320 1330 1340 pF1KA0 -TVVSRMLQPSQGLGRRRRVVPET---AC-SLGPSCSSQQFEEPCHVNSSQLITCRTPAL : . ::.. :: .: . :: .:: . : : ::::.:. ::.::. NP_005 AEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGL--LQCSTVCSVNSSSLLLCRSPAV 1060 1070 1080 1090 1100 1110 1350 1360 1370 1380 1390 1400 pF1KA0 PGLPEDPWVRVEFILDNLVFDFATLNPTP-FSYEADPTLQPLNPEDPTMPFRHKPGSVFS : . : :: : :::. :::. . : :. .: : ::. : :. :.: ::: :.. NP_005 PDRAH-PQ-RVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLKPGHVLD 1120 1130 1140 1150 1160 1170 1410 1420 1430 1440 1450 1460 pF1KA0 VEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEF ::::.:.:..::::: . :: : :.:::::: :::::::.. : : . . .::.: NP_005 VEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGS------GLPQF 1180 1190 1200 1210 1220 1470 1480 1490 1500 1510 1520 pF1KA0 TVQMGNLRFSLGHVQYDGESP-GAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALR .:::::....:: :::..: : .:::: ::.:.:.:...: .:....::::.::::::: NP_005 VVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALR 1230 1240 1250 1260 1270 1280 1530 1540 1550 1560 1570 1580 pF1KA0 DYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFPGH ::.:: .:::.::..: :.:.:::::::::::::.::: :::::::::..:::: ::::: NP_005 DYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFFPGH 1290 1300 1310 1320 1330 1340 1590 1600 1610 1620 1630 pF1KA0 RESPLH-RDLGVPESRR-PTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVA ::. . : :. . ::.::: :::::::::::: .::::: : .:: ::: .:: NP_005 GGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVA 1350 1360 1370 1380 1390 1400 1640 1650 1660 1670 1680 1690 pF1KA0 SLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTF :::..::::::::.:::.::::.::.:.:: .:::::::::::.::::::::.:::::.: NP_005 SLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICLYAF 1410 1420 1430 1440 1450 1460 1700 1710 1720 1730 1740 1750 pF1KA0 VRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVG .:. .:::::::::.:..::::::::.:::::: ::::.::::::::..:::: .: :: NP_005 LREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVL--VG 1470 1480 1490 1500 1510 1520 1760 1770 1780 1790 1800 1810 pF1KA0 PGAGEAQG------VPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVA :::: : : ::..::: :::.:.:::.:::.:::.:..:::. ..::.:::::.: NP_005 PGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLA 1530 1540 1550 1560 1570 1580 1820 1830 1840 1850 1860 pF1KA0 GHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKH--VLRENQDYVP-GER ::: :::::.:: .:. :.::::::::::::::::.::: : . . . . : :: NP_005 GHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPLGEN 1590 1600 1610 1620 1630 1640 1870 1880 1890 1900 1910 1920 pF1KA0 TPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTL : ::: .:::. ::::: ..::: . : .::: : :::::::::::::::::::: NP_005 IPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMKGTL 1650 1660 1670 1680 1690 1700 1930 1940 1950 1960 1970 1980 pF1KA0 QKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINI :::::: ::.:::..::.:.::::.:::::: :..::: : :.:::::::: ::::.: NP_005 QKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNA 1710 1720 1730 1740 1750 1760 1990 2000 2010 2020 2030 2040 pF1KA0 IKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMV .::::..:::..:::.::.: ::::::.:.:: ..::.:::::.:::::::.:::::.:: NP_005 LKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMV 1770 1780 1790 1800 1810 1820 2050 2060 2070 2080 2090 2100 pF1KA0 ERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEED :::::::::. ::: :::::.::::: ::.. ::.:::..:..::::::.::::: NP_005 ERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEED 1830 1840 1850 1860 1870 1880 2110 2120 2130 pF1KA0 GTAQKMQLGYRLQQIAAAVENKVTDL ..::.::. ::::.:: :::::::: NP_005 PVGQKLQLACRLQQVAALVENKVTDL 1890 1900 2135 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:39:56 2016 done: Thu Nov 3 19:40:00 2016 Total Scan time: 27.140 Total Display time: 1.660 Function used was FASTA [36.3.4 Apr, 2011]