FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0418, 940 aa 1>>>pF1KA0418 940 - 940 aa - 940 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7320+/-0.000936; mu= -3.0230+/- 0.057 mean_var=263.0670+/-53.810, 0's: 0 Z-trim(113.9): 32 B-trim: 67 in 1/51 Lambda= 0.079075 statistics sampled from 14503 (14523) to 14503 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.446), width: 16 Scan time: 3.820 The best scores are: opt bits E(32554) CCDS31278.1 SH3PXD2A gene_id:9644|Hs108|chr10 (1105) 6262 728.1 2.2e-209 CCDS78084.1 SH3PXD2B gene_id:285590|Hs108|chr5 ( 430) 620 84.3 5.6e-16 CCDS34291.1 SH3PXD2B gene_id:285590|Hs108|chr5 ( 911) 522 73.3 2.5e-12 >>CCDS31278.1 SH3PXD2A gene_id:9644|Hs108|chr10 (1105 aa) initn: 6262 init1: 6262 opt: 6262 Z-score: 3872.6 bits: 728.1 E(32554): 2.2e-209 Smith-Waterman score: 6262; 100.0% identity (100.0% similar) in 940 aa overlap (1-940:166-1105) 10 20 30 pF1KA0 MILEQYVVVSNYKKQENSELSLQAGEVVDV :::::::::::::::::::::::::::::: CCDS31 GSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDV 140 150 160 170 180 190 40 50 60 70 80 90 pF1KA0 IEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVTVQPYTSQSKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVTVQPYTSQSKD 200 210 220 230 240 250 100 110 120 130 140 150 pF1KA0 EIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGN 260 270 280 290 300 310 160 170 180 190 200 210 pF1KA0 IMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLA 320 330 340 350 360 370 220 230 240 250 260 270 pF1KA0 QGSPAVARIAPQRAQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QGSPAVARIAPQRAQISSPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCI 380 390 400 410 420 430 280 290 300 310 320 330 pF1KA0 SDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVP 440 450 460 470 480 490 340 350 360 370 380 390 pF1KA0 PPAPPSKPKEAEEGPTGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEEPVEDRASGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PPAPPSKPKEAEEGPTGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEEPVEDRASGE 500 510 520 530 540 550 400 410 420 430 440 450 pF1KA0 RRPAQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSARGSSGDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RRPAQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSARGSSGDSD 560 570 580 590 600 610 460 470 480 490 500 510 pF1KA0 SPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTTCCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTTCCSS 620 630 640 650 660 670 520 530 540 550 560 570 pF1KA0 SSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPKPFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPKPFLN 680 690 700 710 720 730 580 590 600 610 620 630 pF1KA0 RAESQSQEKMDISTLRRQLRPTGQLRGGLKGSKSEDSELPPQTASEAPSEGSRRSSSDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RAESQSQEKMDISTLRRQLRPTGQLRGGLKGSKSEDSELPPQTASEAPSEGSRRSSSDLI 740 750 760 770 780 790 640 650 660 670 680 690 pF1KA0 TLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFG 800 810 820 830 840 850 700 710 720 730 740 750 pF1KA0 ELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSK 860 870 880 890 900 910 760 770 780 790 800 810 pF1KA0 KATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSPPPKDNNLSCALRRNESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSPPPKDNNLSCALRRNESL 920 930 940 950 960 970 820 830 840 850 860 870 pF1KA0 TATDGLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSDSPLLPAQRNSIPVSPVRPKPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TATDGLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSDSPLLPAQRNSIPVSPVRPKPI 980 990 1000 1010 1020 1030 880 890 900 910 920 930 pF1KA0 EKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDGVKPFKGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDGVKPFKGW 1040 1050 1060 1070 1080 1090 940 pF1KA0 VPSNYLEKKN :::::::::: CCDS31 VPSNYLEKKN 1100 >>CCDS78084.1 SH3PXD2B gene_id:285590|Hs108|chr5 (430 aa) initn: 877 init1: 345 opt: 620 Z-score: 400.3 bits: 84.3 E(32554): 5.6e-16 Smith-Waterman score: 817; 48.8% identity (68.4% similar) in 285 aa overlap (1-283:152-396) 10 20 30 pF1KA0 MILEQYVVVSNYKKQENSELSLQAGEVVDV :.:::::::.::.:::.::.::..:.:::. CCDS78 FETRPEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDI 130 140 150 160 170 180 40 50 60 70 80 90 pF1KA0 IEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVTVQPYTSQSKD :::::::::::::.::::::::: ::.:.:..:. ... :::::... :::....: CCDS78 IEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPE---EEEKYTVIYPYTARDQD 190 200 210 220 230 100 110 120 130 140 150 pF1KA0 EIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGN :...:.:..::::.::::::: ::: ::::::::::::: : . :. CCDS78 EMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKK----------NSGEPL----- 240 250 260 270 280 160 170 180 190 200 210 pF1KA0 IMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLA :: : : .: ..: . .: ::: . .: CCDS78 ------------------PPKPGPG--SPSHPGALDLDGVSRQQN--AVGREKELLSSQR 290 300 310 320 220 230 240 250 260 pF1KA0 QGSPAVARIAPQRAQISSPNLRTRPPPRRESSL--GFQLPKPPEPPSVEVEYYTIAEFQS .: . :. ::..: ::::::. .. :..::::: ::.:: :::::::::. CCDS78 DGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQT 330 340 350 360 370 380 270 280 290 300 310 320 pF1KA0 CISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPK : :::::..: :.: CCDS78 TIPDGISFQAGLKVEDHKNVHLESPVEVPLRRIKMRTALGKHVAASMEM 390 400 410 420 430 >>CCDS34291.1 SH3PXD2B gene_id:285590|Hs108|chr5 (911 aa) initn: 1222 init1: 370 opt: 522 Z-score: 334.9 bits: 73.3 E(32554): 2.5e-12 Smith-Waterman score: 1244; 32.1% identity (54.2% similar) in 951 aa overlap (1-939:152-910) 10 20 30 pF1KA0 MILEQYVVVSNYKKQENSELSLQAGEVVDV :.:::::::.::.:::.::.::..:.:::. CCDS34 FETRPEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDI 130 140 150 160 170 180 40 50 60 70 80 90 pF1KA0 IEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEEEKYVTVQPYTSQSKD :::::::::::::.::::::::: ::.:.:..:. .. . :::::... :::....: CCDS34 IEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSL---QPEEEEKYTVIYPYTARDQD 190 200 210 220 230 100 110 120 130 140 150 pF1KA0 EIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTRKKNLAGPVEIIGN :...:.:..::::.::::::: ::: ::::::::::::: : . :. CCDS34 EMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKK----------NSGEPL----- 240 250 260 270 280 160 170 180 190 200 210 pF1KA0 IMEISNLLNKKASGDKETPPAEGEGHEAPIAKKEISLPILCNASNGSAVGVPDRTVSRLA :: : : .: ..: . .: ::: . .: CCDS34 ------------------PPKPGPG--SPSHPGALDLDGVSRQQN--AVGREKELLSSQR 290 300 310 320 220 230 240 250 260 pF1KA0 QGSPAVARIAPQRAQISSPNLRTRPPPRRESSL--GFQLPKPPEPPSVEVEYYTIAEFQS .: . :. ::..: ::::::. .. :..::::: ::.:: :::::::::. CCDS34 DGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQT 330 340 350 360 370 380 270 280 290 300 310 320 pF1KA0 CISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPK : :::::..: :.:::.:: .::::.:: .:::::::..::: :: ::. .::. CCDS34 TIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKK------TSNASRPN 390 400 410 420 430 330 340 350 360 370 380 pF1KA0 VPPPAPPSKPKEAEEGPTGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEE-----PV : : . . . : ..: :.. . . .: : : .:: :.. : CCDS34 FLAPLP-HEVTQLRLGEAAALENNTGSEATGPSRPLPDAPHGVMDSGLPWSKDWKGSKDV 440 450 460 470 480 490 390 400 410 420 430 440 pF1KA0 EDRASGERRPAQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSAR .::.. . .. .... . .. .:.. : . : : : .:. : CCDS34 LRKASSDMSASAGYEEISDPDMEE-KPSLPPRKESIIKSEGELLERERERQRTEQL---R 500 510 520 530 540 550 450 460 470 480 490 500 pF1KA0 GSSGDSDSPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITI : . :: . :. : . ..: . : .:. .. :: . . .. CCDS34 GPT--PKPPGVILPMMPAKHIPPA---RDSRRPEPKPDKSRLFQL-KNDMGLECGHKVLA 560 570 580 590 600 510 520 530 540 550 560 pF1KA0 NTTCCSSSSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSV . . .. . .::.. :: :. :: ::. : : : :...: CCDS34 KEV----KKPNLRPISKSKTDL-PEEKPDA----TPQ---------NPFLKSRPQVRP-- 610 620 630 640 570 580 590 600 610 620 pF1KA0 RPKPFLNRAESQSQEKMDISTLRRQLRPTGQLRGGLKGSKSEDSELPPQTASEAPSEGSR .: : . :.....:: .:: .::: .::.:. : .:: . CCDS34 KPAPSPKTEPPQGEDQVDICNLRSKLRP----------AKSQDKSL-------LDGEGPQ 650 660 670 680 630 640 650 660 670 680 pF1KA0 RSSSDLITLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESG ... ... . : :::. ..:: CCDS34 AVGGQDVAFSRSFLPG------EGPG----------RAQD-------------------- 690 700 710 690 700 710 720 730 740 pF1KA0 WWYVRFGELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQAL : :. .: .:.. .. : :. : : : .:: . : CCDS34 ----RTGKQDGLSPKE---ISCRAPPRPA-KTTDPV--------SKSVPVP--------L 720 730 740 750 760 770 780 790 pF1KA0 NTVNQSKKATPPIPSKPPGGFGKTS-GTPAVK---MRNGVRQVAVRPQSVFVSPPPKDNN . . :.. ..:: :: ...: : :. .. ..: : ... :: CCDS34 QEAPQQRPVVPPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAPTPGRALLVPPKAKPF 750 760 770 780 790 800 800 810 820 830 840 850 pF1KA0 LSCALRRNESLTATDGLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSDSPLLPAQRNS :: .:: . : :: . ..:.. :. :.::. : CCDS34 LS------NSLGGQDDTRGKGSLGPWGTGK------IGENREKAAAA------------S 810 820 830 840 860 870 880 890 900 910 pF1KA0 IPVSPVRPKPIEKSQFIHNNLKD-VYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYC .: . ..::: .::..::.:::..:..::::. .:: :.: .:::.: CCDS34 VPNA--------------DGLKDSLYVAVADFEGDKDTSSFQEGTVFEVREKNSSGWWFC 850 860 870 880 920 930 940 pF1KA0 QILDGVKPFKGWVPSNYLEKKN :.:.:. ..::.:::::.:: CCDS34 QVLSGAPSWEGWIPSNYLRKKP 890 900 910 940 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:52:47 2016 done: Wed Nov 2 18:52:47 2016 Total Scan time: 3.820 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]