FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0431, 667 aa 1>>>pF1KA0431 667 - 667 aa - 667 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5361+/-0.000416; mu= 4.7684+/- 0.026 mean_var=185.2137+/-41.032, 0's: 0 Z-trim(115.4): 26 B-trim: 0 in 0/57 Lambda= 0.094241 statistics sampled from 25845 (25865) to 25845 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.303), width: 16 Scan time: 10.970 The best scores are: opt bits E(85289) NP_001287657 (OMIM: 614693) ATM interactor isoform ( 667) 4359 605.8 1.7e-172 NP_056066 (OMIM: 614693) ATM interactor isoform 1 ( 823) 4359 605.8 2e-172 >>NP_001287657 (OMIM: 614693) ATM interactor isoform 2 [ (667 aa) initn: 4359 init1: 4359 opt: 4359 Z-score: 3218.0 bits: 605.8 E(85289): 1.7e-172 Smith-Waterman score: 4359; 100.0% identity (100.0% similar) in 667 aa overlap (1-667:1-667) 10 20 30 40 50 60 pF1KA0 MKMHAEKKHKCSKCSNSYGTEWDLKRHAEDCGKTFRCTCGCPYASRTALQSHIYRTGHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMHAEKKHKCSKCSNSYGTEWDLKRHAEDCGKTFRCTCGCPYASRTALQSHIYRTGHEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PAEHRDPPSKKRKMENCAQNQKLSNKTIESLNNQPIPRPDTQELEASEIKLEPSFEDSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAEHRDPPSKKRKMENCAQNQKLSNKTIESLNNQPIPRPDTQELEASEIKLEPSFEDSCG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 SNTDKQTLTTPPRYPQKLLLPKPKVALVKLPVMQFSVMPVFVPTADSSAQPVVLGVDQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNTDKQTLTTPPRYPQKLLLPKPKVALVKLPVMQFSVMPVFVPTADSSAQPVVLGVDQGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ATGAVHLMPLSVGTLILGLDSEACSLKESLPLFKIANPIAGEPISTGVQVNFGKSPSNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATGAVHLMPLSVGTLILGLDSEACSLKESLPLFKIANPIAGEPISTGVQVNFGKSPSNPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QELGNTCQKNSISSINVQTDLSYASQNFIPSAQWATADSSVSSCSQTDLSFDSQVSLPIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELGNTCQKNSISSINVQTDLSYASQNFIPSAQWATADSSVSSCSQTDLSFDSQVSLPIS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 VHTQTFLPSSKVTSSIAAQTDAFMDTCFQSGGVSRETQTSGIESPTDDHVQMDQAGMCGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHTQTFLPSSKVTSSIAAQTDAFMDTCFQSGGVSRETQTSGIESPTDDHVQMDQAGMCGD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 IFESVHSSYNVATGNIISNSLVAETVTHSLLPQNEPKTLNQDIEKSAPIINFSAQNSMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFESVHSSYNVATGNIISNSLVAETVTHSLLPQNEPKTLNQDIEKSAPIINFSAQNSMLP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 SQNMTDNQTQTIDLLSDLENILSSNLPAQTLDHRSLLSDTNPGPDTQLPSGPAQNPGIDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQNMTDNQTQTIDLLSDLENILSSNLPAQTLDHRSLLSDTNPGPDTQLPSGPAQNPGIDF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 DIEEFFSASNIQTQTEESELSTMTTEPVLESLDIETQTDFLLADTSAQSYGCRGNSNFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIEEFFSASNIQTQTEESELSTMTTEPVLESLDIETQTDFLLADTSAQSYGCRGNSNFLG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 LEMFDTQTQTDLNFFLDSSPHLPLGSILKHSSFSVSTDSSDTETQTEGVSTAKNIPALES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEMFDTQTQTDLNFFLDSSPHLPLGSILKHSSFSVSTDSSDTETQTEGVSTAKNIPALES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KVQLNSTETQTMSSGFETLGSLFFTSNETQTAMDDFLLADLAWNTMESQFSSVETQTSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVQLNSTETQTMSSGFETLGSLFFTSNETQTAMDDFLLADLAWNTMESQFSSVETQTSAE 610 620 630 640 650 660 pF1KA0 PHTVSNF ::::::: NP_001 PHTVSNF >>NP_056066 (OMIM: 614693) ATM interactor isoform 1 [Hom (823 aa) initn: 4359 init1: 4359 opt: 4359 Z-score: 3216.6 bits: 605.8 E(85289): 2e-172 Smith-Waterman score: 4359; 100.0% identity (100.0% similar) in 667 aa overlap (1-667:157-823) 10 20 30 pF1KA0 MKMHAEKKHKCSKCSNSYGTEWDLKRHAED :::::::::::::::::::::::::::::: NP_056 GPKFYCCPIEGCPRGPERPFSQFSLVKQHFMKMHAEKKHKCSKCSNSYGTEWDLKRHAED 130 140 150 160 170 180 40 50 60 70 80 90 pF1KA0 CGKTFRCTCGCPYASRTALQSHIYRTGHEIPAEHRDPPSKKRKMENCAQNQKLSNKTIES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CGKTFRCTCGCPYASRTALQSHIYRTGHEIPAEHRDPPSKKRKMENCAQNQKLSNKTIES 190 200 210 220 230 240 100 110 120 130 140 150 pF1KA0 LNNQPIPRPDTQELEASEIKLEPSFEDSCGSNTDKQTLTTPPRYPQKLLLPKPKVALVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LNNQPIPRPDTQELEASEIKLEPSFEDSCGSNTDKQTLTTPPRYPQKLLLPKPKVALVKL 250 260 270 280 290 300 160 170 180 190 200 210 pF1KA0 PVMQFSVMPVFVPTADSSAQPVVLGVDQGSATGAVHLMPLSVGTLILGLDSEACSLKESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PVMQFSVMPVFVPTADSSAQPVVLGVDQGSATGAVHLMPLSVGTLILGLDSEACSLKESL 310 320 330 340 350 360 220 230 240 250 260 270 pF1KA0 PLFKIANPIAGEPISTGVQVNFGKSPSNPLQELGNTCQKNSISSINVQTDLSYASQNFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PLFKIANPIAGEPISTGVQVNFGKSPSNPLQELGNTCQKNSISSINVQTDLSYASQNFIP 370 380 390 400 410 420 280 290 300 310 320 330 pF1KA0 SAQWATADSSVSSCSQTDLSFDSQVSLPISVHTQTFLPSSKVTSSIAAQTDAFMDTCFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SAQWATADSSVSSCSQTDLSFDSQVSLPISVHTQTFLPSSKVTSSIAAQTDAFMDTCFQS 430 440 450 460 470 480 340 350 360 370 380 390 pF1KA0 GGVSRETQTSGIESPTDDHVQMDQAGMCGDIFESVHSSYNVATGNIISNSLVAETVTHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GGVSRETQTSGIESPTDDHVQMDQAGMCGDIFESVHSSYNVATGNIISNSLVAETVTHSL 490 500 510 520 530 540 400 410 420 430 440 450 pF1KA0 LPQNEPKTLNQDIEKSAPIINFSAQNSMLPSQNMTDNQTQTIDLLSDLENILSSNLPAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LPQNEPKTLNQDIEKSAPIINFSAQNSMLPSQNMTDNQTQTIDLLSDLENILSSNLPAQT 550 560 570 580 590 600 460 470 480 490 500 510 pF1KA0 LDHRSLLSDTNPGPDTQLPSGPAQNPGIDFDIEEFFSASNIQTQTEESELSTMTTEPVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LDHRSLLSDTNPGPDTQLPSGPAQNPGIDFDIEEFFSASNIQTQTEESELSTMTTEPVLE 610 620 630 640 650 660 520 530 540 550 560 570 pF1KA0 SLDIETQTDFLLADTSAQSYGCRGNSNFLGLEMFDTQTQTDLNFFLDSSPHLPLGSILKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SLDIETQTDFLLADTSAQSYGCRGNSNFLGLEMFDTQTQTDLNFFLDSSPHLPLGSILKH 670 680 690 700 710 720 580 590 600 610 620 630 pF1KA0 SSFSVSTDSSDTETQTEGVSTAKNIPALESKVQLNSTETQTMSSGFETLGSLFFTSNETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SSFSVSTDSSDTETQTEGVSTAKNIPALESKVQLNSTETQTMSSGFETLGSLFFTSNETQ 730 740 750 760 770 780 640 650 660 pF1KA0 TAMDDFLLADLAWNTMESQFSSVETQTSAEPHTVSNF ::::::::::::::::::::::::::::::::::::: NP_056 TAMDDFLLADLAWNTMESQFSSVETQTSAEPHTVSNF 790 800 810 820 667 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:54:53 2016 done: Wed Nov 2 18:54:55 2016 Total Scan time: 10.970 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]