FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0433, 1243 aa 1>>>pF1KA0433 1243 - 1243 aa - 1243 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0044+/-0.000422; mu= 15.0220+/- 0.026 mean_var=106.3030+/-21.954, 0's: 0 Z-trim(113.7): 104 B-trim: 557 in 2/54 Lambda= 0.124395 statistics sampled from 23040 (23144) to 23040 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.271), width: 16 Scan time: 13.930 The best scores are: opt bits E(85289) NP_001263206 (OMIM: 611648) inositol hexakisphosph (1243) 8263 1494.5 0 NP_001332802 (OMIM: 611648) inositol hexakisphosph (1242) 8243 1490.9 0 NP_056031 (OMIM: 611648) inositol hexakisphosphate (1222) 7363 1333.0 0 NP_001332805 (OMIM: 611648) inositol hexakisphosph (1182) 7081 1282.4 0 NP_001332807 (OMIM: 611648) inositol hexakisphosph (1181) 7061 1278.8 0 NP_001332804 (OMIM: 611648) inositol hexakisphosph (1124) 6537 1184.8 0 XP_016864763 (OMIM: 611648) PREDICTED: inositol he (1145) 6537 1184.8 0 NP_001332803 (OMIM: 611648) inositol hexakisphosph (1164) 6537 1184.8 0 NP_001332800 (OMIM: 611648) inositol hexakisphosph (1185) 6537 1184.8 0 NP_001332806 (OMIM: 611648) inositol hexakisphosph (1123) 6517 1181.2 0 XP_016864762 (OMIM: 611648) PREDICTED: inositol he (1163) 6517 1181.2 0 XP_005277593 (OMIM: 611648) PREDICTED: inositol he (1237) 6361 1153.2 0 NP_001332801 (OMIM: 611648) inositol hexakisphosph (1200) 5647 1025.0 0 XP_011541592 (OMIM: 611648) PREDICTED: inositol he (1038) 5644 1024.5 0 XP_005277598 (OMIM: 611648) PREDICTED: inositol he (1139) 5644 1024.5 0 XP_006714640 (OMIM: 611648) PREDICTED: inositol he (1160) 5644 1024.5 0 XP_005277596 (OMIM: 611648) PREDICTED: inositol he (1197) 5644 1024.5 0 XP_006714639 (OMIM: 611648) PREDICTED: inositol he (1218) 5644 1024.5 0 XP_005277591 (OMIM: 611648) PREDICTED: inositol he (1258) 5644 1024.5 0 NP_001268400 (OMIM: 611648) inositol hexakisphosph (1278) 5644 1024.5 0 XP_005277592 (OMIM: 611648) PREDICTED: inositol he (1257) 5624 1020.9 0 XP_011520554 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_011520551 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_011520552 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_016878225 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_016878226 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_016878224 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_011520556 (OMIM: 610979) PREDICTED: inositol he (1479) 5430 986.1 0 XP_016878228 (OMIM: 610979) PREDICTED: inositol he (1458) 5141 934.3 0 XP_016878227 (OMIM: 610979) PREDICTED: inositol he (1471) 5076 922.6 0 XP_016878243 (OMIM: 610979) PREDICTED: inositol he (1366) 4963 902.3 0 XP_016878246 (OMIM: 610979) PREDICTED: inositol he (1366) 4963 902.3 0 XP_006720849 (OMIM: 610979) PREDICTED: inositol he (1366) 4963 902.3 0 XP_016878245 (OMIM: 610979) PREDICTED: inositol he (1366) 4963 902.3 0 XP_016878244 (OMIM: 610979) PREDICTED: inositol he (1366) 4963 902.3 0 NP_001177143 (OMIM: 610979) inositol hexakisphosph (1406) 4963 902.3 0 XP_016878240 (OMIM: 610979) PREDICTED: inositol he (1408) 4963 902.3 0 NP_001124331 (OMIM: 610979) inositol hexakisphosph (1408) 4963 902.3 0 XP_005254861 (OMIM: 610979) PREDICTED: inositol he (1408) 4963 902.3 0 NP_055474 (OMIM: 610979) inositol hexakisphosphate (1408) 4963 902.3 0 XP_016878238 (OMIM: 610979) PREDICTED: inositol he (1408) 4963 902.3 0 XP_016878237 (OMIM: 610979) PREDICTED: inositol he (1408) 4963 902.3 0 XP_016878239 (OMIM: 610979) PREDICTED: inositol he (1408) 4963 902.3 0 XP_016878232 (OMIM: 610979) PREDICTED: inositol he (1429) 4963 902.3 0 XP_016878229 (OMIM: 610979) PREDICTED: inositol he (1429) 4963 902.3 0 XP_016878230 (OMIM: 610979) PREDICTED: inositol he (1429) 4963 902.3 0 XP_005254860 (OMIM: 610979) PREDICTED: inositol he (1429) 4963 902.3 0 XP_016878233 (OMIM: 610979) PREDICTED: inositol he (1429) 4963 902.3 0 XP_016878231 (OMIM: 610979) PREDICTED: inositol he (1429) 4963 902.3 0 XP_016878236 (OMIM: 610979) PREDICTED: inositol he (1416) 4955 900.9 0 >>NP_001263206 (OMIM: 611648) inositol hexakisphosphate (1243 aa) initn: 8263 init1: 8263 opt: 8263 Z-score: 8011.5 bits: 1494.5 E(85289): 0 Smith-Waterman score: 8263; 100.0% identity (100.0% similar) in 1243 aa overlap (1-1243:1-1243) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1210 1220 1230 1240 >>NP_001332802 (OMIM: 611648) inositol hexakisphosphate (1242 aa) initn: 4613 init1: 4613 opt: 8243 Z-score: 7992.1 bits: 1490.9 E(85289): 0 Smith-Waterman score: 8243; 99.9% identity (99.9% similar) in 1243 aa overlap (1-1243:1-1242) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQ-D 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1200 1210 1220 1230 1240 >>NP_056031 (OMIM: 611648) inositol hexakisphosphate and (1222 aa) initn: 7341 init1: 7341 opt: 7363 Z-score: 7138.7 bits: 1333.0 E(85289): 0 Smith-Waterman score: 8075; 98.3% identity (98.3% similar) in 1243 aa overlap (1-1243:1-1222) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::: ::::::::::::::::::::::: NP_056 YARTHRKKLTSSGCID---------------------GFELYSMVPSICPLETLHNALSL 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_056 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1180 1190 1200 1210 1220 >>NP_001332805 (OMIM: 611648) inositol hexakisphosphate (1182 aa) initn: 7081 init1: 7081 opt: 7081 Z-score: 6865.4 bits: 1282.4 E(85289): 0 Smith-Waterman score: 7727; 95.1% identity (95.1% similar) in 1243 aa overlap (1-1243:1-1182) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD ::::::::::::::::::::::::::::::::::::: NP_001 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVG----------------------- 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::: NP_001 --------------------------------------FELYSMVPSICPLETLHNALSL 1060 1070 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1080 1090 1100 1110 1120 1130 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1140 1150 1160 1170 1180 >>NP_001332807 (OMIM: 611648) inositol hexakisphosphate (1181 aa) initn: 4432 init1: 3646 opt: 7061 Z-score: 6846.0 bits: 1278.8 E(85289): 0 Smith-Waterman score: 7707; 95.0% identity (95.0% similar) in 1243 aa overlap (1-1243:1-1181) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQ-D 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD ::::::::::::::::::::::::::::::::::::: NP_001 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVG----------------------- 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::: NP_001 --------------------------------------FELYSMVPSICPLETLHNALSL 1060 1070 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1080 1090 1100 1110 1120 1130 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1140 1150 1160 1170 1180 >>NP_001332804 (OMIM: 611648) inositol hexakisphosphate (1124 aa) initn: 7323 init1: 6537 opt: 6537 Z-score: 6338.1 bits: 1184.8 E(85289): 0 Smith-Waterman score: 7215; 90.4% identity (90.4% similar) in 1243 aa overlap (1-1243:1-1124) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::: NP_001 KSPLPRSRKTATND---------------------------------------------- 970 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD ::::::::::::::::::::::::: NP_001 ------------VVSENANYLRTPRTLVEQKQNPTVG----------------------- 980 990 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::: NP_001 --------------------------------------FELYSMVPSICPLETLHNALSL 1000 1010 1020 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1030 1040 1050 1060 1070 1080 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1090 1100 1110 1120 >>XP_016864763 (OMIM: 611648) PREDICTED: inositol hexaki (1145 aa) initn: 7581 init1: 6537 opt: 6537 Z-score: 6338.0 bits: 1184.8 E(85289): 0 Smith-Waterman score: 7393; 92.1% identity (92.1% similar) in 1243 aa overlap (1-1243:1-1145) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::: XP_016 KSPLPRSRKTATND---------------------------------------------- 970 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD :::::::::::::::::::::::: XP_016 ------------VVSENANYLRTPRTLVEQKQNPTV------------------------ 980 990 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::::::::::::::::::::::::: XP_016 ----------------DATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL 1000 1010 1020 1030 1040 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1050 1060 1070 1080 1090 1100 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: XP_016 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1110 1120 1130 1140 >>NP_001332803 (OMIM: 611648) inositol hexakisphosphate (1164 aa) initn: 7311 init1: 6537 opt: 6537 Z-score: 6337.9 bits: 1184.8 E(85289): 0 Smith-Waterman score: 7563; 93.6% identity (93.6% similar) in 1243 aa overlap (1-1243:1-1164) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::: NP_001 KSPLPRSRKTATND---------------------------------------------- 970 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ------------VVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD 980 990 1000 1010 1020 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::: ::::::::::::::::::::::: NP_001 YARTHRKKLTSSGCID---------------------GFELYSMVPSICPLETLHNALSL 1030 1040 1050 1060 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1070 1080 1090 1100 1110 1120 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1130 1140 1150 1160 >>NP_001332800 (OMIM: 611648) inositol hexakisphosphate (1185 aa) initn: 7863 init1: 6537 opt: 6537 Z-score: 6337.8 bits: 1184.8 E(85289): 0 Smith-Waterman score: 7751; 95.3% identity (95.3% similar) in 1243 aa overlap (1-1243:1-1185) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::: NP_001 KSPLPRSRKTATND---------------------------------------------- 970 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ------------VVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD 980 990 1000 1010 1020 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL 1030 1040 1050 1060 1070 1080 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1090 1100 1110 1120 1130 1140 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1150 1160 1170 1180 >>NP_001332806 (OMIM: 611648) inositol hexakisphosphate (1123 aa) initn: 4432 init1: 3646 opt: 6517 Z-score: 6318.7 bits: 1181.2 E(85289): 0 Smith-Waterman score: 7195; 90.3% identity (90.3% similar) in 1243 aa overlap (1-1243:1-1123) 10 20 30 40 50 60 pF1KA0 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEAPRFFVGPEDTEINPGNYRHFFHHADEDDEEEDDSPPERQIVVGICSMAKKSKSKPM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILERISLFKYITVVVFEEEVILNEPVENWPLCDCLISFHSKGFPLDKAVAYAKLRNPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VINDLNMQYLIQDRREVYSILQAEGILLPRYAILNRDPNNPKECNLIEGEDHVEVNGEVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSPESNVRKTGSYIYEEFM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVILNAREKLIAWKVCLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFHIPWSI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEENKPKLEQLKTVLEMYGHFSGINRKVQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 LTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQ-D 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSAN 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGLLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDI 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKLEIAKGYCT 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGA 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGC 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDKNLPSGYGYRPASRENEGRRPFKIDNDDEPHTSKRDEVDRAVILFKPMVSEPIHIHR 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 KSPLPRSRKTATNDEESPLSVSSPEGTGTWLHYTSGVGTGRRRRRSGEQITSSPVSPKSL :::::::::::::: NP_001 KSPLPRSRKTATND---------------------------------------------- 960 970 1030 1040 1050 1060 1070 1080 pF1KA0 AFTSSIFGSWQQVVSENANYLRTPRTLVEQKQNPTVGSHCAGLFSTSVLGGSSSAPNLQD ::::::::::::::::::::::::: NP_001 ------------VVSENANYLRTPRTLVEQKQNPTVG----------------------- 980 990 1090 1100 1110 1120 1130 1140 pF1KA0 YARTHRKKLTSSGCIDDATRGSAVKRFSISFARHPTNGFELYSMVPSICPLETLHNALSL :::::::::::::::::::::: NP_001 --------------------------------------FELYSMVPSICPLETLHNALSL 1000 1010 1020 1150 1160 1170 1180 1190 1200 pF1KA0 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVDEFLASIASPSSDVPRKTAEISSTALRSSPIMRKKVSLNTYTPAKILPTPPATLKST 1030 1040 1050 1060 1070 1080 1210 1220 1230 1240 pF1KA0 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK ::::::::::::::::::::::::::::::::::::::::::: NP_001 KASSKPATSGPSSAVVPNTSSRKKNITSKTETHEHKKNTGKKK 1090 1100 1110 1120 1243 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:41:21 2016 done: Fri Nov 4 00:41:23 2016 Total Scan time: 13.930 Total Display time: 0.530 Function used was FASTA [36.3.4 Apr, 2011]