FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0437, 1596 aa 1>>>pF1KA0437 1596 - 1596 aa - 1596 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7313+/-0.00126; mu= -6.6632+/- 0.077 mean_var=549.0486+/-110.921, 0's: 0 Z-trim(114.4): 23 B-trim: 49 in 1/53 Lambda= 0.054735 statistics sampled from 14993 (15005) to 14993 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.461), width: 16 Scan time: 5.500 The best scores are: opt bits E(32554) CCDS11923.2 SETBP1 gene_id:26040|Hs108|chr18 (1596) 10681 859.8 0 CCDS1113.2 ASH1L gene_id:55870|Hs108|chr1 (2964) 1217 112.7 1.8e-23 CCDS45859.1 SETBP1 gene_id:26040|Hs108|chr18 ( 242) 1181 108.8 2.3e-23 >>CCDS11923.2 SETBP1 gene_id:26040|Hs108|chr18 (1596 aa) initn: 10681 init1: 10681 opt: 10681 Z-score: 4577.1 bits: 859.8 E(32554): 0 Smith-Waterman score: 10681; 99.9% identity (100.0% similar) in 1596 aa overlap (1-1596:1-1596) 10 20 30 40 50 60 pF1KA0 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 AYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 SGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 PPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 AFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 RQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 TMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVET 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 IHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 IYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 TQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 HLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 NPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEEL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 ITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 RPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 AASPFMRPTVPPPQFHTNSHIKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSA ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS11 AASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 SLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 SEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 KRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 RKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 LAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 RQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 SQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAP 1510 1520 1530 1540 1550 1560 1570 1580 1590 pF1KA0 AQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP :::::::::::::::::::::::::::::::::::: CCDS11 AQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP 1570 1580 1590 >>CCDS1113.2 ASH1L gene_id:55870|Hs108|chr1 (2964 aa) initn: 1133 init1: 344 opt: 1217 Z-score: 534.8 bits: 112.7 E(32554): 1.8e-23 Smith-Waterman score: 1701; 30.9% identity (56.7% similar) in 1512 aa overlap (231-1572:501-1958) 210 220 230 240 250 pF1KA0 FTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGR-ETASTSKIPALEPVAS . :. : : :.: ::.. : : . .. CCDS11 RQNKESILEKFSVRKEIINLEKEMFNEGTCIQQDSFSSSEKGSYETSKHEKQPPVYCTSP 480 490 500 510 520 530 260 270 280 290 300 310 pF1KA0 FAKAQGKK--GSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSP---APPSSSAECNGLQPL : : . ..: . .: ....: .:::. .: .:: .:.. : CCDS11 DFKMGGASDVSTAKSPFSAVGESNLP------SPSPTVSVNPLTRSPPETSSQLAPNPLL 540 550 560 570 580 320 330 340 350 360 pF1KA0 VDQDGGGTKEPPEPPTVGSKKKSSKKDVI---------SQTIPNPDLDWVKNAQKA---- ... .: : .::... .:.. . : .: .: : .:. CCDS11 LSSTTELIEEISE--SVGKNQFTSESTHLNVGHRSVGHSISIECKGIDKEVNDSKTTHID 590 600 610 620 630 640 370 380 390 400 pF1KA0 ---FDNTEGKREGYSADSA-QEASPARQNVSS--ASNP-------ENDSSHVRITIPIKA .... ::. . ...:. . .:. : .: ...: ...: .. : CCDS11 IPRISSSLGKKPSLTSESSIHTITPSVVNFTSLFSNKPFLKLGAVSASDKHCQV-----A 650 660 670 680 690 410 420 430 440 450 pF1KA0 PSLDPTNHKR--KKRQSIKAVVEKIMPEKALAS--GITMS-SEVVNRI----LSNSEG-- ::. . ... :::.. : :.. ... : :. . ::. . . ::::.. CCDS11 ESLSTSLQSKPLKKRKGRKPRWTKVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEP 700 710 720 730 740 750 460 470 480 490 500 pF1KA0 -----NKKDP----------RVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPR-KPP : : :.::::: . .::..: ...:: . . . . CCDS11 AKFMKNIGPPSFVDHDFLKRRLPKLSK---STAPSLALL--ADSEKPSHKSFATHKLSSS 760 770 780 790 800 810 510 520 530 540 550 pF1KA0 MVMTPPTCTD-HSPSRKLPEIQH-PKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPP : .. .: ..:.: :. .. :.. . . : . : . :.. ..: ::: CCDS11 MCVSSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASK------VFSLQSKEEQEPP 820 830 840 850 860 560 570 580 590 600 610 pF1KA0 SAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPV----SPISR . : . . ..:.: .: :::::::.: :. :..: :: . CCDS11 I---LQPEIEIPSFKQGLSV-SPFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKL 870 880 890 900 910 920 620 630 640 650 660 pF1KA0 EFPGTKKRKRRRNLAKLAQLVPGED-----KP----MS--EMKFHKKVGKL--GVLDKKT : . ..:. . . :: .: .: :: ::. ::. : : : : CCDS11 ESESDNHRSSSDFFESEDQLQDPDDLDDSHRPSVCSMSDLEMEPDKKITKRNNGQLMKTI 930 940 950 960 970 980 670 680 690 700 710 pF1KA0 IKTINKMKTLKRKNILNQILSCSSSVALKAKAPPE----TSPGAAAIESKLGKQINVSKR :. ::::::::::..:::::: : . :.:. . .: ::.. ::::.::::::. CCDS11 IRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKK 990 1000 1010 1020 1030 1040 720 730 740 750 760 770 pF1KA0 GTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAV----PSNFQSLVASSPA :::::::.:::::.. : :.. . ...: :. : . : ..:: CCDS11 GTIYIGKRRGRKPKTVLNGILSGSPTSLAVLEQTAQQAAGSALGQILPPLLPSSASSSEI 1050 1060 1070 1080 1090 1100 780 790 800 810 820 830 pF1KA0 AMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQ----PISALPTKTQKGIHSGTWKLS :. .: .:..:. ::.:....: : ...: :. : . : ..: .: .:: CCDS11 LPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHSRQGSMIQTLAMKKASKGRRRLS 1110 1120 1130 1140 1150 1160 840 850 860 870 880 pF1KA0 PPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEK-SSESR :: :. :::::: :. :::: : ::.:::::.::::::::::::::::::.::: .... CCDS11 PPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKK 1170 1180 1190 1200 1210 1220 890 900 910 920 930 940 pF1KA0 RRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRK--SLQN ::.::. :: ::. .: :..: :. :. : .:.....:. :.:::.: .:.: CCDS11 RRHSFEHVSLIPPETSTVLSSLKEKHKHKCKRRNHD-YLSYDKMKRQKRKRKKKYPQLRN 1230 1240 1250 1260 1270 1280 950 960 970 980 990 1000 pF1KA0 RDDLQFLADLEELITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYL :.: .:.:.:::::.... .::.:::. : .. :.::::::. .: : . ::: :. CCDS11 RQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYI 1290 1300 1310 1320 1330 1340 1010 1020 1030 1040 1050 1060 pF1KA0 RRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPM----MNL :. :: ::::::: : ..:...::....:.:. : ..: :::::. :. ..: CCDS11 RKP-DL--KKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGL 1350 1360 1370 1380 1390 1070 1080 1090 1100 1110 1120 pF1KA0 GYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHTNSHIKMSGAAKHKAKHGVHLQGP-VS ::::.:: :: :: . .:::.. .:. .. : :: :: . : .. CCDS11 GYYGRYPPTLYPP----PPSPSFTTPLPPPSYMHAGHLLLNPAKYHKKKHKLLRQEAFLT 1400 1410 1420 1430 1440 1450 1130 1140 1150 1160 1170 pF1KA0 MGLGDMQPSLNPPKVGSASLSSGRLHKRKHKHKHKHKEDRI-------LGTHDNLSGLFA . . . :.: .. : . ..::.:.:::.: : . : .. : : . CCDS11 TSRTPLLSMSTYPSV-PPEMAYGWMVEHKHRHRHKHREHRSSEQPQVSMDTGSSRSVLES 1460 1470 1480 1490 1500 1510 1180 1190 1200 1210 1220 pF1KA0 GKATGFSSHILSERLSSADKE-----LPLVSEKNK--HKEKQ--KHQHSEAGHKAS--KN : :.. ..:: . .:. : .: ... ..:.: ... ::.. : .. CCDS11 LKRYRFGKDAVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHREPSESSPLALGLQT 1520 1530 1540 1550 1560 1570 1230 1240 1250 1260 1270 pF1KA0 NFEVD------TLSTLSLSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENL ...: .:: ... .. ... :. .: . . :: : :. ...: . ... CCDS11 PLQIDCSESSPSLSLGGFTPNSEPASSDEHTNLFTSAIGSC--RVSNPNSSGRKKLTDSP 1580 1590 1600 1610 1620 1630 1280 1290 1300 1310 1320 pF1KA0 DVFSEMN------------PSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSS .:: .. :::.. . ..::. : . . : .. . .:: ::: CCDS11 GLFSAQDTSLNRLHRKESLPSNERAVQTLAGSQPTSDK--PSQRPSESTNCSPTRK-RSS 1640 1650 1660 1670 1680 1330 1340 1350 1360 1370 pF1KA0 YDSSMSP--GMPS--PHLKVD-QTAVHS------KNEGSVPTMMTRKKPAAVDSVTIPPA .:. : :.:: :.: .. . .: : .:: . : : .. :.. ... ::. CCDS11 SESTSSTVNGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEP--MEKSIDAVIATASAPPS 1690 1700 1710 1720 1730 1740 1380 1390 1400 1410 pF1KA0 --PVLSL-----------LAASAATSDAVGSSLK------------KRFKRREIEAIQCE : : : . :.:::. ..:.. ...:: .::.: . CCDS11 SSPGRSHSKDRTLGKPDSLLVPAVTSDSCNNSISLLSEKLTSSCSPHHIKRSVVEAMQRQ 1750 1760 1770 1780 1790 1800 1420 1430 1440 1450 1460 1470 pF1KA0 VRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRD .:::::: :::.:::::::::::::::.::::..:::::::.: ::::: : : . CCDS11 ARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQ----AVV 1810 1820 1830 1840 1850 1860 1480 1490 1500 1510 1520 1530 pF1KA0 QMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPL .: ... . . .. . : : : ::. .::::.. . : CCDS11 SMQAFQAAQFVNPELNRDEEGAALHLSP----DTVTDVIEAVVQSVNLNPEHKKGLKRKG 1870 1880 1890 1900 1910 1540 1550 1560 1570 1580 1590 pF1KA0 PPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGS :::. . . : .::.. : :: . : CCDS11 WLLEEQTRKKQKPLPEEEEQENNKSFNEAPVEIP--SPSETPAKPSEPESTLQPVLSLIP 1920 1930 1940 1950 1960 1970 pF1KA0 ESEVLP CCDS11 REKKPPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGK 1980 1990 2000 2010 2020 2030 >>CCDS45859.1 SETBP1 gene_id:26040|Hs108|chr18 (242 aa) initn: 1181 init1: 1181 opt: 1181 Z-score: 533.1 bits: 108.8 E(32554): 2.3e-23 Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KA0 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 AYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPE CCDS45 IKDSSKEEVWKRRGGQGIPFKKQFLSQERAMCFSCPRNPFPAKPGSLTLPFHSEPAVWAQ 190 200 210 220 230 240 1596 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 18:55:38 2016 done: Wed Nov 2 18:55:39 2016 Total Scan time: 5.500 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]