Result of FASTA (omim) for
pF1KA0456
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0456, 1071 aa
1>>>pF1KA0456 1071 - 1071 aa - 1071 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3301+/-0.00055; mu= -7.3535+/- 0.034
mean_var=331.7007+/-70.687, 0's: 0 Z-trim(116.0): 370 B-trim: 71 in 1/52
Lambda= 0.070421
statistics sampled from 26481 (26867) to 26481 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.315), width: 16
Scan time: 16.080
The best scores are: opt bits E(85289)
NP_056141 (OMIM: 606524) SLIT-ROBO Rho GTPase-acti (1071) 7020 728.5 4.7e-209
XP_005277567 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1071) 7020 728.5 4.7e-209
NP_001164108 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1070) 7001 726.6 1.8e-208
XP_005277568 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1070) 7001 726.6 1.8e-208
XP_011507658 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 986) 5511 575.2 6.3e-163
XP_011507656 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1084) 5511 575.2 6.8e-163
XP_011507657 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1083) 5492 573.3 2.6e-162
XP_011507661 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 841) 5471 571.1 9.2e-162
XP_016856330 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 840) 5452 569.2 3.5e-161
XP_005277571 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 790) 5160 539.5 2.9e-152
NP_001287881 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 789) 5141 537.6 1.1e-151
XP_005277572 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 789) 5141 537.6 1.1e-151
XP_016856327 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 4516 474.1 1.6e-132
XP_016856328 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 4516 474.1 1.6e-132
XP_016856329 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 4516 474.1 1.6e-132
NP_001333130 (OMIM: 188470,606523) SLIT-ROBO Rho G (1062) 4235 445.6 7e-124
NP_001028289 (OMIM: 606525) SLIT-ROBO Rho GTPase-a (1075) 3353 356.0 6.7e-97
XP_016863064 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1093) 3347 355.4 1e-96
NP_001258799 (OMIM: 614703) SLIT-ROBO Rho GTPase-a ( 459) 2897 309.4 3e-83
XP_016857574 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 458) 2878 307.5 1.1e-82
NP_001316913 (OMIM: 614704) SLIT-ROBO Rho GTPase-a ( 459) 2871 306.8 1.9e-82
XP_016863069 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 709) 2873 307.1 2.3e-82
NP_001258801 (OMIM: 614704) SLIT-ROBO Rho GTPase-a ( 458) 2852 304.8 7.1e-82
XP_016857575 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 428) 2706 290.0 2e-77
XP_011540317 (OMIM: 614704) PREDICTED: SLIT-ROBO R ( 428) 2680 287.4 1.2e-76
XP_011536883 (OMIM: 188470,606523) PREDICTED: SLIT (1045) 2320 251.0 2.6e-65
XP_011536882 (OMIM: 188470,606523) PREDICTED: SLIT (1045) 2320 251.0 2.6e-65
NP_065813 (OMIM: 188470,606523) SLIT-ROBO Rho GTPa (1085) 2320 251.1 2.6e-65
XP_011532605 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 591) 1979 216.2 4.4e-55
XP_016857578 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1913 209.3 2.7e-53
XP_005277478 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1913 209.3 2.7e-53
XP_016857577 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1913 209.3 2.7e-53
XP_005277479 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1913 209.3 2.7e-53
XP_016857580 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 305) 1894 207.4 1e-52
NP_001317613 (OMIM: 614703) SLIT-ROBO Rho GTPase-a ( 305) 1894 207.4 1e-52
XP_016857581 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 305) 1894 207.4 1e-52
XP_016857638 (OMIM: 614704) PREDICTED: SLIT-ROBO R ( 306) 1893 207.3 1.1e-52
XP_005277556 (OMIM: 614704) PREDICTED: SLIT-ROBO R ( 306) 1893 207.3 1.1e-52
XP_016857576 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 307) 1759 193.7 1.4e-48
XP_011532597 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1104) 1378 155.4 1.7e-36
NP_055665 (OMIM: 606525) SLIT-ROBO Rho GTPase-acti (1099) 1375 155.0 2.1e-36
XP_011532603 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 941) 1371 154.6 2.5e-36
XP_011532598 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1085) 1372 154.7 2.6e-36
XP_016863068 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 876) 1369 154.4 2.7e-36
XP_016863067 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 1369 154.4 3e-36
XP_016863066 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 1369 154.4 3e-36
XP_016863065 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 1369 154.4 3e-36
XP_016863063 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1117) 1369 154.4 3.3e-36
NP_001657 (OMIM: 300023) rho GTPase-activating pro ( 946) 1082 125.2 1.7e-27
NP_001158213 (OMIM: 300023) rho GTPase-activating ( 986) 1082 125.2 1.8e-27
>>NP_056141 (OMIM: 606524) SLIT-ROBO Rho GTPase-activati (1071 aa)
initn: 7020 init1: 7020 opt: 7020 Z-score: 3874.1 bits: 728.5 E(85289): 4.7e-209
Smith-Waterman score: 7020; 99.9% identity (99.9% similar) in 1071 aa overlap (1-1071:1-1071)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_056 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KA0 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
1030 1040 1050 1060 1070
>>XP_005277567 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (1071 aa)
initn: 7020 init1: 7020 opt: 7020 Z-score: 3874.1 bits: 728.5 E(85289): 4.7e-209
Smith-Waterman score: 7020; 99.9% identity (99.9% similar) in 1071 aa overlap (1-1071:1-1071)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KA0 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
1030 1040 1050 1060 1070
>>NP_001164108 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (1070 aa)
initn: 5250 init1: 5250 opt: 7001 Z-score: 3863.7 bits: 726.6 E(85289): 1.8e-208
Smith-Waterman score: 7001; 99.8% identity (99.8% similar) in 1071 aa overlap (1-1071:1-1070)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLID-CCDLGYHASLNRALRTFLSAEL
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_001 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
960 970 980 990 1000 1010
1030 1040 1050 1060 1070
pF1KA0 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
1020 1030 1040 1050 1060 1070
>>XP_005277568 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (1070 aa)
initn: 5250 init1: 5250 opt: 7001 Z-score: 3863.7 bits: 726.6 E(85289): 1.8e-208
Smith-Waterman score: 7001; 99.8% identity (99.8% similar) in 1071 aa overlap (1-1071:1-1070)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLID-CCDLGYHASLNRALRTFLSAEL
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
960 970 980 990 1000 1010
1030 1040 1050 1060 1070
pF1KA0 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
1020 1030 1040 1050 1060 1070
>>XP_011507658 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (986 aa)
initn: 6181 init1: 5471 opt: 5511 Z-score: 3046.1 bits: 575.2 E(85289): 6.3e-163
Smith-Waterman score: 6159; 98.5% identity (98.5% similar) in 957 aa overlap (1-944:1-957)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
730 740 750 760 770 780
790 800 810 820 830
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANIN-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINNNLHL
790 800 810 820 830 840
840 850 860 870 880
pF1KA0 --------KQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNTKPVTTKQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPK
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 EGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQRSN
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 ATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPA
XP_011 PTSKNPTTGATPSSSLRRLSQLYNFH
970 980
>>XP_011507656 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (1084 aa)
initn: 7006 init1: 5471 opt: 5511 Z-score: 3045.5 bits: 575.2 E(85289): 6.8e-163
Smith-Waterman score: 6984; 98.7% identity (98.7% similar) in 1084 aa overlap (1-1071:1-1084)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
730 740 750 760 770 780
790 800 810 820 830
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANIN-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINNNLHL
790 800 810 820 830 840
840 850 860 870 880
pF1KA0 --------KQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNTKPVTTKQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPK
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 EGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIE
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 ATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPA
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 FQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDK
1030 1040 1050 1060 1070 1080
1070
pF1KA0 SCTV
::::
XP_011 SCTV
>>XP_011507657 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (1083 aa)
initn: 5236 init1: 3701 opt: 5492 Z-score: 3035.1 bits: 573.3 E(85289): 2.6e-162
Smith-Waterman score: 6965; 98.6% identity (98.6% similar) in 1084 aa overlap (1-1071:1-1083)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLID-CCDLGYHASLNRALRTFLSAEL
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
720 730 740 750 760 770
790 800 810 820 830
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANIN-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINNNLHL
780 790 800 810 820 830
840 850 860 870 880
pF1KA0 --------KQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNTKPVTTKQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPK
840 850 860 870 880 890
890 900 910 920 930 940
pF1KA0 EGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIE
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KA0 ATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPA
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KA0 FQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDK
1020 1030 1040 1050 1060 1070
1070
pF1KA0 SCTV
::::
XP_011 SCTV
1080
>>XP_011507661 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (841 aa)
initn: 5471 init1: 5471 opt: 5471 Z-score: 3025.1 bits: 571.1 E(85289): 9.2e-162
Smith-Waterman score: 5471; 99.9% identity (99.9% similar) in 835 aa overlap (1-835:1-835)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINNFHCG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
XP_011 C
>>XP_016856330 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (840 aa)
initn: 3701 init1: 3701 opt: 5452 Z-score: 3014.7 bits: 569.2 E(85289): 3.5e-161
Smith-Waterman score: 5452; 99.8% identity (99.8% similar) in 835 aa overlap (1-835:1-834)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLID-CCDLGYHASLNRALRTFLSAEL
250 260 270 280 290
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINNFHCG
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
XP_016 C
840
>>XP_005277571 (OMIM: 606524) PREDICTED: SLIT-ROBO Rho G (790 aa)
initn: 5160 init1: 5160 opt: 5160 Z-score: 2854.7 bits: 539.5 E(85289): 2.9e-152
Smith-Waterman score: 5160; 99.9% identity (99.9% similar) in 787 aa overlap (1-787:1-787)
10 20 30 40 50 60
pF1KA0 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTPVEDSTQDVTAE
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
:::::::
XP_005 YIVVQDTLIS
790
1071 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:42:57 2016 done: Fri Nov 4 00:43:00 2016
Total Scan time: 16.080 Total Display time: 0.510
Function used was FASTA [36.3.4 Apr, 2011]