FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0464, 324 aa 1>>>pF1KA0464 324 - 324 aa - 324 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2514+/-0.000335; mu= 7.3515+/- 0.021 mean_var=117.5268+/-23.750, 0's: 0 Z-trim(118.4): 97 B-trim: 1476 in 1/52 Lambda= 0.118306 statistics sampled from 31260 (31360) to 31260 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.368), width: 16 Scan time: 6.740 The best scores are: opt bits E(85289) NP_001158229 (OMIM: 605551) carboxyl-terminal PDZ ( 501) 2036 358.1 2.1e-98 NP_055512 (OMIM: 605551) carboxyl-terminal PDZ lig ( 506) 2016 354.7 2.3e-97 NP_001239597 (OMIM: 608165) PTB domain-containing ( 291) 199 44.5 0.00033 XP_016859795 (OMIM: 608165) PREDICTED: PTB domain- ( 304) 199 44.5 0.00034 NP_057399 (OMIM: 608165) PTB domain-containing eng ( 304) 199 44.5 0.00034 XP_006712652 (OMIM: 608165) PREDICTED: PTB domain- ( 322) 199 44.5 0.00036 XP_016859792 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 199 44.5 0.0004 XP_016859793 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 199 44.5 0.0004 XP_016859794 (OMIM: 608165) PREDICTED: PTB domain- ( 366) 199 44.5 0.0004 XP_011509631 (OMIM: 608165) PREDICTED: PTB domain- ( 376) 199 44.5 0.00041 XP_006712646 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 199 44.5 0.00041 XP_006712643 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 199 44.5 0.00041 XP_006712644 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 199 44.5 0.00041 XP_006712645 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 199 44.5 0.00041 XP_006712647 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 199 44.5 0.00041 XP_006712648 (OMIM: 608165) PREDICTED: PTB domain- ( 379) 199 44.5 0.00041 NP_001191008 (OMIM: 607815) ankyrin repeat and ste ( 290) 193 43.5 0.00066 NP_001190995 (OMIM: 607815) ankyrin repeat and ste ( 357) 193 43.5 0.00079 NP_001190996 (OMIM: 607815) ankyrin repeat and ste ( 394) 193 43.5 0.00086 XP_005269089 (OMIM: 607815) PREDICTED: ankyrin rep ( 266) 190 42.9 0.00087 NP_001191009 (OMIM: 607815) ankyrin repeat and ste ( 266) 190 42.9 0.00087 XP_016875154 (OMIM: 607815) PREDICTED: ankyrin rep ( 425) 193 43.5 0.00092 NP_001190994 (OMIM: 607815) ankyrin repeat and ste ( 290) 190 43.0 0.00094 XP_016875151 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 193 43.6 0.001 NP_001190999 (OMIM: 607815) ankyrin repeat and ste ( 426) 190 43.0 0.0013 XP_016875153 (OMIM: 607815) PREDICTED: ankyrin rep ( 429) 190 43.0 0.0013 NP_001190998 (OMIM: 607815) ankyrin repeat and ste ( 450) 190 43.0 0.0014 XP_016875152 (OMIM: 607815) PREDICTED: ankyrin rep ( 476) 190 43.1 0.0014 XP_016875150 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 190 43.1 0.0014 XP_016875149 (OMIM: 607815) PREDICTED: ankyrin rep ( 486) 190 43.1 0.0015 NP_001191010 (OMIM: 607815) ankyrin repeat and ste ( 254) 185 42.1 0.0015 NP_858056 (OMIM: 607815) ankyrin repeat and steril ( 510) 190 43.1 0.0015 XP_016875148 (OMIM: 607815) PREDICTED: ankyrin rep ( 511) 190 43.1 0.0015 XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 193 43.8 0.0022 NP_064525 (OMIM: 607815) ankyrin repeat and steril ( 414) 185 42.2 0.0023 XP_006719572 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 193 43.8 0.0023 XP_006719569 (OMIM: 607815) PREDICTED: ankyrin rep (1283) 193 43.8 0.0024 XP_006719568 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 193 43.8 0.0024 NP_001190997 (OMIM: 607815) ankyrin repeat and ste ( 460) 185 42.2 0.0025 XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 190 43.2 0.0032 XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 190 43.2 0.0032 XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 190 43.3 0.0033 XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 190 43.3 0.0033 XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 190 43.3 0.0033 XP_005269085 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 190 43.3 0.0033 XP_016875141 (OMIM: 607815) PREDICTED: ankyrin rep (1281) 190 43.3 0.0034 XP_006719567 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 190 43.3 0.0034 XP_016875140 (OMIM: 607815) PREDICTED: ankyrin rep (1285) 190 43.3 0.0034 XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 185 42.4 0.0057 XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 185 42.4 0.0057 >>NP_001158229 (OMIM: 605551) carboxyl-terminal PDZ liga (501 aa) initn: 2206 init1: 2036 opt: 2036 Z-score: 1887.5 bits: 358.1 E(85289): 2.1e-98 Smith-Waterman score: 2036; 99.7% identity (99.7% similar) in 311 aa overlap (1-311:1-311) 10 20 30 40 50 60 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 GESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 EGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQ 250 260 270 280 290 300 310 320 pF1KA0 QTQVAVAQVLLSLLPTSQAPLSWA ::::::::: : NP_001 QTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSG 310 320 330 340 350 360 >>NP_055512 (OMIM: 605551) carboxyl-terminal PDZ ligand (506 aa) initn: 2133 init1: 1448 opt: 2016 Z-score: 1869.0 bits: 354.7 E(85289): 2.3e-97 Smith-Waterman score: 2016; 98.1% identity (98.1% similar) in 316 aa overlap (1-311:1-316) 10 20 30 40 50 60 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 EFKAKNIKKKKVSIMVSVDGVKVILKKKKK-----KKEWTWDESKMLVMQDPIYRIFYVS :::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_055 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL 250 260 270 280 290 300 300 310 320 pF1KA0 QQQQQQTQVAVAQVLLSLLPTSQAPLSWA :::::::::::::: : NP_055 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE 310 320 330 340 350 360 >>NP_001239597 (OMIM: 608165) PTB domain-containing engu (291 aa) initn: 195 init1: 102 opt: 199 Z-score: 196.6 bits: 44.5 E(85289): 0.00033 Smith-Waterman score: 239; 26.4% identity (55.8% similar) in 269 aa overlap (20-281:14-240) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... NP_001 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . NP_001 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: : .:. :.::::.. .. :. NP_001 CADDKTDKRIFTFICKDSESNKHLCYVFDSEK--CAEEITLTIGQAFDLAYRKFLE---- 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT .: .: :... :..: .. .. . . .:. .: :: . .: NP_001 --SGGKDVETRK----------QIAGLQK----RIQDLETENMELKNKVQD-LENQLRIT 160 170 180 190 240 250 260 270 280 290 pF1KA0 DLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQ ...: .:: : .. : :. :: . .:: : ::. : NP_001 QVSA--PPAGSMTPKSPSTDIFDMIPFSP---ISHQSSMPTRNGTQPPPVPSRSTEIKRD 200 210 220 230 240 250 300 310 320 pF1KA0 LLQQQQQQTQVAVAQVLLSLLPTSQAPLSWA NP_001 LFGAEPFDPFNCGAADFPPDIQSKLDEMQRQRWRGSKWD 260 270 280 290 >>XP_016859795 (OMIM: 608165) PREDICTED: PTB domain-cont (304 aa) initn: 195 init1: 102 opt: 199 Z-score: 196.3 bits: 44.5 E(85289): 0.00034 Smith-Waterman score: 239; 26.4% identity (55.8% similar) in 269 aa overlap (20-281:14-240) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . XP_016 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: : .:. :.::::.. .. :. XP_016 CADDKTDKRIFTFICKDSESNKHLCYVFDSEK--CAEEITLTIGQAFDLAYRKFLE---- 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT .: .: :... :..: .. .. . . .:. .: :: . .: XP_016 --SGGKDVETRK----------QIAGLQK----RIQDLETENMELKNKVQD-LENQLRIT 160 170 180 190 240 250 260 270 280 290 pF1KA0 DLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQ ...: .:: : .. : :. :: . .:: : ::. : XP_016 QVSA--PPAGSMTPKSPSTDIFDMIPFSP---ISHQSSMPTRNGTQPPPVPSRSTEIKRD 200 210 220 230 240 250 300 310 320 pF1KA0 LLQQQQQQTQVAVAQVLLSLLPTSQAPLSWA XP_016 LFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC 260 270 280 290 300 >>NP_057399 (OMIM: 608165) PTB domain-containing engulfm (304 aa) initn: 195 init1: 102 opt: 199 Z-score: 196.3 bits: 44.5 E(85289): 0.00034 Smith-Waterman score: 239; 26.4% identity (55.8% similar) in 269 aa overlap (20-281:14-240) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... NP_057 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . NP_057 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: : .:. :.::::.. .. :. NP_057 CADDKTDKRIFTFICKDSESNKHLCYVFDSEK--CAEEITLTIGQAFDLAYRKFLE---- 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT .: .: :... :..: .. .. . . .:. .: :: . .: NP_057 --SGGKDVETRK----------QIAGLQK----RIQDLETENMELKNKVQD-LENQLRIT 160 170 180 190 240 250 260 270 280 290 pF1KA0 DLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQ ...: .:: : .. : :. :: . .:: : ::. : NP_057 QVSA--PPAGSMTPKSPSTDIFDMIPFSP---ISHQSSMPTRNGTQPPPVPSRSTEIKRD 200 210 220 230 240 250 300 310 320 pF1KA0 LLQQQQQQTQVAVAQVLLSLLPTSQAPLSWA NP_057 LFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC 260 270 280 290 300 >>XP_006712652 (OMIM: 608165) PREDICTED: PTB domain-cont (322 aa) initn: 195 init1: 102 opt: 199 Z-score: 196.0 bits: 44.5 E(85289): 0.00036 Smith-Waterman score: 239; 26.4% identity (55.8% similar) in 269 aa overlap (20-281:14-240) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... XP_006 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . XP_006 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: : .:. :.::::.. .. :. XP_006 CADDKTDKRIFTFICKDSESNKHLCYVFDSEK--CAEEITLTIGQAFDLAYRKFLE---- 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT .: .: :... :..: .. .. . . .:. .: :: . .: XP_006 --SGGKDVETRK----------QIAGLQK----RIQDLETENMELKNKVQD-LENQLRIT 160 170 180 190 240 250 260 270 280 290 pF1KA0 DLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQ ...: .:: : .. : :. :: . .:: : ::. : XP_006 QVSA--PPAGSMTPKSPSTDIFDMIPFSP---ISHQSSMPTRNGTQPPPVPSRSTEIKRD 200 210 220 230 240 250 300 310 320 pF1KA0 LLQQQQQQTQVAVAQVLLSLLPTSQAPLSWA XP_006 LFGAEPFDPFNCGAADFPPDIQSKLDEMQVTILIDWPINDLFHFDMGQRECYVPKLWFPS 260 270 280 290 300 310 >>XP_016859792 (OMIM: 608165) PREDICTED: PTB domain-cont (366 aa) initn: 164 init1: 102 opt: 199 Z-score: 195.1 bits: 44.5 E(85289): 0.0004 Smith-Waterman score: 226; 28.0% identity (62.8% similar) in 164 aa overlap (20-176:14-161) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . XP_016 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: .. .:. :.::::.. .. :. . XP_016 CADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAE--EITLTIGQAFDLAYRKFLESGGK 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT ... XP_016 DVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQR 160 170 180 190 200 210 >>XP_016859793 (OMIM: 608165) PREDICTED: PTB domain-cont (366 aa) initn: 164 init1: 102 opt: 199 Z-score: 195.1 bits: 44.5 E(85289): 0.0004 Smith-Waterman score: 226; 28.0% identity (62.8% similar) in 164 aa overlap (20-176:14-161) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . XP_016 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: .. .:. :.::::.. .. :. . XP_016 CADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAE--EITLTIGQAFDLAYRKFLESGGK 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT ... XP_016 DVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQR 160 170 180 190 200 210 >>XP_016859794 (OMIM: 608165) PREDICTED: PTB domain-cont (366 aa) initn: 164 init1: 102 opt: 199 Z-score: 195.1 bits: 44.5 E(85289): 0.0004 Smith-Waterman score: 226; 28.0% identity (62.8% similar) in 164 aa overlap (20-176:14-161) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... XP_016 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . XP_016 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: .. .:. :.::::.. .. :. . XP_016 CADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAE--EITLTIGQAFDLAYRKFLESGGK 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT ... XP_016 DVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQR 160 170 180 190 200 210 >>XP_011509631 (OMIM: 608165) PREDICTED: PTB domain-cont (376 aa) initn: 164 init1: 102 opt: 199 Z-score: 194.9 bits: 44.5 E(85289): 0.00041 Smith-Waterman score: 226; 28.0% identity (62.8% similar) in 164 aa overlap (20-176:14-161) 10 20 30 40 50 pF1KA0 MPSKTKYNLVDDGHDLRIPLHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIR .:. .:. .: : ..::..:: .: .:.. . :.:... XP_011 MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLK 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 YEFKAKNIKKK------KVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFY . :..:::. :: ...:. :::.. : :. .. . ..:: . XP_011 F---ARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQH-----------NCQLHRISF 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQ . :. : .::..: .:. :: : :: :.: .. .:. :.::::.. .. :. . XP_011 CADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAE--EITLTIGQAFDLAYRKFLESGGK 110 120 130 140 150 180 190 200 210 220 230 pF1KA0 NADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT ... XP_011 DVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSAPPLLHNMSDHEQHVFQR 160 170 180 190 200 210 324 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:00:37 2016 done: Wed Nov 2 19:00:38 2016 Total Scan time: 6.740 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]