FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0471, 370 aa 1>>>pF1KA0471 370 - 370 aa - 370 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8638+/-0.00109; mu= -3.8752+/- 0.065 mean_var=296.6939+/-61.284, 0's: 0 Z-trim(112.0): 39 B-trim: 98 in 1/50 Lambda= 0.074459 statistics sampled from 12811 (12834) to 12811 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.394), width: 16 Scan time: 2.450 The best scores are: opt bits E(32554) CCDS58046.1 RABGAP1L gene_id:9910|Hs108|chr1 ( 370) 2372 268.2 8.2e-72 CCDS81407.1 RABGAP1L gene_id:9910|Hs108|chr1 ( 308) 1708 196.8 2.1e-50 CCDS55662.1 RABGAP1L gene_id:9910|Hs108|chr1 ( 253) 1504 174.8 7.3e-44 CCDS6848.2 RABGAP1 gene_id:23637|Hs108|chr9 (1069) 1384 162.5 1.6e-39 CCDS1314.1 RABGAP1L gene_id:9910|Hs108|chr1 ( 815) 495 66.9 7.3e-11 >>CCDS58046.1 RABGAP1L gene_id:9910|Hs108|chr1 (370 aa) initn: 2372 init1: 2372 opt: 2372 Z-score: 1402.7 bits: 268.2 E(32554): 8.2e-72 Smith-Waterman score: 2372; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KA0 MEEGVPCPAPAAKLTPPVKKSQDMHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEEGVPCPAPAAKLTPPVKKSQDMHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 DLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 QQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 KQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLRE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 MELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPA 310 320 330 340 350 360 370 pF1KA0 PVTQPPKEST :::::::::: CCDS58 PVTQPPKEST 370 >>CCDS81407.1 RABGAP1L gene_id:9910|Hs108|chr1 (308 aa) initn: 1708 init1: 1708 opt: 1708 Z-score: 1018.3 bits: 196.8 E(32554): 2.1e-50 Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308) 70 80 90 100 110 120 pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY :::::::::::::::::::::::::::::: CCDS81 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY 10 20 30 40 50 60 130 140 150 160 170 180 pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET 70 80 90 100 110 120 190 200 210 220 230 240 pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE 130 140 150 160 170 180 250 260 270 280 290 300 pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK 190 200 210 220 230 240 310 320 330 340 350 360 pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES 250 260 270 280 290 300 370 pF1KA0 T : CCDS81 T >>CCDS55662.1 RABGAP1L gene_id:9910|Hs108|chr1 (253 aa) initn: 1503 init1: 1503 opt: 1504 Z-score: 901.0 bits: 174.8 E(32554): 7.3e-44 Smith-Waterman score: 1504; 98.4% identity (98.8% similar) in 245 aa overlap (126-370:9-253) 100 110 120 130 140 150 pF1KA0 CNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELV : .::::::::::::::::::::::::: CCDS55 MIENSSWSMTFEERENRRLQEASMRLEQENDDLAHELV 10 20 30 160 170 180 190 200 210 pF1KA0 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE 40 50 60 70 80 90 220 230 240 250 260 270 pF1KA0 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL 100 110 120 130 140 150 280 290 300 310 320 330 pF1KA0 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA 160 170 180 190 200 210 340 350 360 370 pF1KA0 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST ::::::::::::::::::::::::::::::::::: CCDS55 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST 220 230 240 250 >>CCDS6848.2 RABGAP1 gene_id:23637|Hs108|chr9 (1069 aa) initn: 1448 init1: 1384 opt: 1384 Z-score: 823.1 bits: 162.5 E(32554): 1.6e-39 Smith-Waterman score: 1384; 69.5% identity (91.1% similar) in 302 aa overlap (54-355:763-1064) 30 40 50 60 70 80 pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR :: :::.::: .:::::::::::::::::: CCDS68 TAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYR 740 750 760 770 780 790 90 100 110 120 130 140 pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL .::::..::: :::.:. ::::::::::.::::.: :::::..:..:::::::::.::: CCDS68 SEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRL 800 810 820 830 840 850 150 160 170 180 190 200 pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL :::::::::::::::::::.:::.::.:::.::::::.:::.:...:::::. :::.::: CCDS68 EQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQL 860 870 880 890 900 910 210 220 230 240 250 260 pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC ::. :..:.::: ::::...::..::::::::: ::::::.:.: :.: .. :. :..: CCDS68 KEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERC 920 930 940 950 960 970 270 280 290 300 310 320 pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE ..:.::: .: .. .: .::.::..::.:::::::::::::::::::.::::.:: CCDS68 REFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLE 980 990 1000 1010 1020 1030 330 340 350 360 370 pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST :. : .::.::::..::..::.:::::::.: CCDS68 HHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC 1040 1050 1060 >>CCDS1314.1 RABGAP1L gene_id:9910|Hs108|chr1 (815 aa) initn: 495 init1: 495 opt: 495 Z-score: 308.5 bits: 66.9 E(32554): 7.3e-11 Smith-Waterman score: 495; 98.7% identity (98.7% similar) in 77 aa overlap (54-130:735-811) 30 40 50 60 70 80 pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR :: ::::::::::::::::::::::::::: CCDS13 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR 710 720 730 740 750 760 90 100 110 120 130 140 pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL ::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKFVYL 770 780 790 800 810 150 160 170 180 190 200 pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL 370 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 19:01:57 2016 done: Wed Nov 2 19:01:58 2016 Total Scan time: 2.450 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]