Result of FASTA (omim) for
pF1KA0471
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0471, 370 aa
1>>>pF1KA0471 370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7747+/-0.000459; mu= -3.1584+/- 0.028
mean_var=359.4191+/-74.416, 0's: 0 Z-trim(119.8): 55 B-trim: 593 in 2/53
Lambda= 0.067651
statistics sampled from 34100 (34156) to 34100 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.4), width: 16
Scan time: 7.910
The best scores are: opt bits E(85289)
NP_001230694 (OMIM: 609238) rab GTPase-activating ( 370) 2372 245.4 1.6e-64
XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase- (1014) 1997 209.3 3.2e-53
XP_011508525 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 1997 209.3 3.3e-53
XP_005245737 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 1997 209.3 3.3e-53
NP_001317918 (OMIM: 609238) rab GTPase-activating ( 308) 1708 180.5 4.5e-45
XP_016858485 (OMIM: 609238) PREDICTED: rab GTPase- ( 308) 1708 180.5 4.5e-45
XP_016858486 (OMIM: 609238) PREDICTED: rab GTPase- ( 308) 1708 180.5 4.5e-45
XP_016858487 (OMIM: 609238) PREDICTED: rab GTPase- ( 253) 1504 160.5 3.9e-39
NP_001230693 (OMIM: 609238) rab GTPase-activating ( 253) 1504 160.5 3.9e-39
XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 1384 149.4 3e-35
XP_011516744 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 1384 149.4 3e-35
XP_016870057 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
NP_036329 (OMIM: 615882) rab GTPase-activating pro (1069) 1384 149.5 3.4e-35
XP_011516743 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_016870058 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_016870056 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_011516742 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_006711756 (OMIM: 609238) PREDICTED: rab GTPase- ( 985) 1243 135.7 4.5e-31
XP_016858488 (OMIM: 609238) PREDICTED: rab GTPase- ( 242) 954 106.8 5.5e-23
XP_016858483 (OMIM: 609238) PREDICTED: rab GTPase- ( 778) 495 62.6 3.6e-09
NP_055672 (OMIM: 609238) rab GTPase-activating pro ( 815) 495 62.6 3.7e-09
>>NP_001230694 (OMIM: 609238) rab GTPase-activating prot (370 aa)
initn: 2372 init1: 2372 opt: 2372 Z-score: 1279.5 bits: 245.4 E(85289): 1.6e-64
Smith-Waterman score: 2372; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KA0 MEEGVPCPAPAAKLTPPVKKSQDMHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEGVPCPAPAAKLTPPVKKSQDMHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLRE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 MELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPA
310 320 330 340 350 360
370
pF1KA0 PVTQPPKEST
::::::::::
NP_001 PVTQPPKEST
370
>>XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase-acti (1014 aa)
initn: 1997 init1: 1997 opt: 1997 Z-score: 1076.5 bits: 209.3 E(85289): 3.2e-53
Smith-Waterman score: 1997; 99.7% identity (99.7% similar) in 317 aa overlap (54-370:698-1014)
30 40 50 60 70 80
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
:: :::::::::::::::::::::::::::
XP_005 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR
670 680 690 700 710 720
90 100 110 120 130 140
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
730 740 750 760 770 780
150 160 170 180 190 200
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
850 860 870 880 890 900
270 280 290 300 310 320
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
910 920 930 940 950 960
330 340 350 360 370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
970 980 990 1000 1010
>>XP_011508525 (OMIM: 609238) PREDICTED: rab GTPase-acti (1051 aa)
initn: 1997 init1: 1997 opt: 1997 Z-score: 1076.3 bits: 209.3 E(85289): 3.3e-53
Smith-Waterman score: 1997; 99.7% identity (99.7% similar) in 317 aa overlap (54-370:735-1051)
30 40 50 60 70 80
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
:: :::::::::::::::::::::::::::
XP_011 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR
710 720 730 740 750 760
90 100 110 120 130 140
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
770 780 790 800 810 820
150 160 170 180 190 200
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
830 840 850 860 870 880
210 220 230 240 250 260
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
890 900 910 920 930 940
270 280 290 300 310 320
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
950 960 970 980 990 1000
330 340 350 360 370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
1010 1020 1030 1040 1050
>>XP_005245737 (OMIM: 609238) PREDICTED: rab GTPase-acti (1051 aa)
initn: 1997 init1: 1997 opt: 1997 Z-score: 1076.3 bits: 209.3 E(85289): 3.3e-53
Smith-Waterman score: 1997; 99.7% identity (99.7% similar) in 317 aa overlap (54-370:735-1051)
30 40 50 60 70 80
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
:: :::::::::::::::::::::::::::
XP_005 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR
710 720 730 740 750 760
90 100 110 120 130 140
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
770 780 790 800 810 820
150 160 170 180 190 200
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
830 840 850 860 870 880
210 220 230 240 250 260
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
890 900 910 920 930 940
270 280 290 300 310 320
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
950 960 970 980 990 1000
330 340 350 360 370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
1010 1020 1030 1040 1050
>>NP_001317918 (OMIM: 609238) rab GTPase-activating prot (308 aa)
initn: 1708 init1: 1708 opt: 1708 Z-score: 930.2 bits: 180.5 E(85289): 4.5e-45
Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308)
70 80 90 100 110 120
pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
::::::::::::::::::::::::::::::
NP_001 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
10 20 30 40 50 60
130 140 150 160 170 180
pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
70 80 90 100 110 120
190 200 210 220 230 240
pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
250 260 270 280 290 300
370
pF1KA0 T
:
NP_001 T
>>XP_016858485 (OMIM: 609238) PREDICTED: rab GTPase-acti (308 aa)
initn: 1708 init1: 1708 opt: 1708 Z-score: 930.2 bits: 180.5 E(85289): 4.5e-45
Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308)
70 80 90 100 110 120
pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
::::::::::::::::::::::::::::::
XP_016 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
10 20 30 40 50 60
130 140 150 160 170 180
pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
70 80 90 100 110 120
190 200 210 220 230 240
pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
250 260 270 280 290 300
370
pF1KA0 T
:
XP_016 T
>>XP_016858486 (OMIM: 609238) PREDICTED: rab GTPase-acti (308 aa)
initn: 1708 init1: 1708 opt: 1708 Z-score: 930.2 bits: 180.5 E(85289): 4.5e-45
Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308)
70 80 90 100 110 120
pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
::::::::::::::::::::::::::::::
XP_016 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
10 20 30 40 50 60
130 140 150 160 170 180
pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
70 80 90 100 110 120
190 200 210 220 230 240
pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
250 260 270 280 290 300
370
pF1KA0 T
:
XP_016 T
>>XP_016858487 (OMIM: 609238) PREDICTED: rab GTPase-acti (253 aa)
initn: 1503 init1: 1503 opt: 1504 Z-score: 823.6 bits: 160.5 E(85289): 3.9e-39
Smith-Waterman score: 1504; 98.4% identity (98.8% similar) in 245 aa overlap (126-370:9-253)
100 110 120 130 140 150
pF1KA0 CNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELV
: .:::::::::::::::::::::::::
XP_016 MIENSSWSMTFEERENRRLQEASMRLEQENDDLAHELV
10 20 30
160 170 180 190 200 210
pF1KA0 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
40 50 60 70 80 90
220 230 240 250 260 270
pF1KA0 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KA0 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
160 170 180 190 200 210
340 350 360 370
pF1KA0 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
:::::::::::::::::::::::::::::::::::
XP_016 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
220 230 240 250
>>NP_001230693 (OMIM: 609238) rab GTPase-activating prot (253 aa)
initn: 1503 init1: 1503 opt: 1504 Z-score: 823.6 bits: 160.5 E(85289): 3.9e-39
Smith-Waterman score: 1504; 98.4% identity (98.8% similar) in 245 aa overlap (126-370:9-253)
100 110 120 130 140 150
pF1KA0 CNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELV
: .:::::::::::::::::::::::::
NP_001 MIENSSWSMTFEERENRRLQEASMRLEQENDDLAHELV
10 20 30
160 170 180 190 200 210
pF1KA0 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
40 50 60 70 80 90
220 230 240 250 260 270
pF1KA0 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KA0 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
160 170 180 190 200 210
340 350 360 370
pF1KA0 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
:::::::::::::::::::::::::::::::::::
NP_001 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
220 230 240 250
>>XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase-acti (900 aa)
initn: 1448 init1: 1384 opt: 1384 Z-score: 753.7 bits: 149.4 E(85289): 3e-35
Smith-Waterman score: 1384; 69.5% identity (91.1% similar) in 302 aa overlap (54-355:594-895)
30 40 50 60 70 80
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
:: :::.::: .::::::::::::::::::
XP_016 TAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYR
570 580 590 600 610 620
90 100 110 120 130 140
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
.::::..::: :::.:. ::::::::::.::::.: :::::..:..:::::::::.:::
XP_016 SEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRL
630 640 650 660 670 680
150 160 170 180 190 200
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
:::::::::::::::::::.:::.::.:::.::::::.:::.:...:::::. :::.:::
XP_016 EQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQL
690 700 710 720 730 740
210 220 230 240 250 260
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
::. :..:.::: ::::...::..::::::::: ::::::.:.: :.: .. :. :..:
XP_016 KEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERC
750 760 770 780 790 800
270 280 290 300 310 320
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
..:.::: .: .. .: .::.::..::.:::::::::::::::::::.::::.::
XP_016 REFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLE
810 820 830 840 850 860
330 340 350 360 370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
:. : .::.::::..::..::.:::::::.:
XP_016 HHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
870 880 890 900
370 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:01:58 2016 done: Wed Nov 2 19:01:59 2016
Total Scan time: 7.910 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]