FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0487, 180 aa
1>>>pF1KA0487 180 - 180 aa - 180 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5571+/-0.00028; mu= 17.4193+/- 0.018
mean_var=64.7529+/-12.844, 0's: 0 Z-trim(118.3): 23 B-trim: 0 in 0/60
Lambda= 0.159384
statistics sampled from 31147 (31172) to 31147 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.365), width: 16
Scan time: 6.080
The best scores are: opt bits E(85289)
NP_061967 (OMIM: 609229) diphosphoinositol polypho ( 180) 1217 287.7 7e-78
NP_950241 (OMIM: 609229) diphosphoinositol polypho ( 181) 1205 284.9 4.8e-77
NP_060629 (OMIM: 300528) diphosphoinositol polypho ( 164) 1005 238.9 3.1e-63
NP_001291892 (OMIM: 300527) diphosphoinositol poly ( 164) 995 236.6 1.5e-62
NP_694853 (OMIM: 300527) diphosphoinositol polypho ( 164) 995 236.6 1.5e-62
XP_011536098 (OMIM: 609229) PREDICTED: diphosphoin ( 128) 850 203.1 1.4e-52
NP_001287953 (OMIM: 609229) diphosphoinositol poly ( 128) 850 203.1 1.4e-52
XP_011536097 (OMIM: 609229) PREDICTED: diphosphoin ( 128) 850 203.1 1.4e-52
NP_001287952 (OMIM: 609229) diphosphoinositol poly ( 128) 850 203.1 1.4e-52
NP_006694 (OMIM: 609228) diphosphoinositol polypho ( 172) 845 202.1 3.8e-52
NP_001287951 (OMIM: 609229) diphosphoinositol poly ( 129) 838 200.4 9.5e-52
XP_011536096 (OMIM: 609229) PREDICTED: diphosphoin ( 129) 838 200.4 9.5e-52
NP_009014 (OMIM: 606261) nucleoside diphosphate-li ( 316) 152 43.0 0.00055
NP_932158 (OMIM: 606261) nucleoside diphosphate-li ( 147) 141 40.2 0.0018
NP_671701 (OMIM: 602852) NUDT2 gene product [Homo ( 147) 138 39.5 0.003
NP_671702 (OMIM: 602852) NUDT2 gene product [Homo ( 147) 138 39.5 0.003
NP_001231319 (OMIM: 602852) NUDT2 gene product [Ho ( 147) 138 39.5 0.003
NP_001152 (OMIM: 602852) NUDT2 gene product [Homo ( 147) 138 39.5 0.003
NP_001229306 (OMIM: 609844) m7GpppN-mRNA hydrolase ( 385) 138 39.9 0.0059
XP_016864652 (OMIM: 609844) PREDICTED: m7GpppN-mRN ( 405) 138 39.9 0.0062
NP_689837 (OMIM: 609844) m7GpppN-mRNA hydrolase is ( 420) 138 39.9 0.0063
>>NP_061967 (OMIM: 609229) diphosphoinositol polyphospha (180 aa)
initn: 1217 init1: 1217 opt: 1217 Z-score: 1519.2 bits: 287.7 E(85289): 7e-78
Smith-Waterman score: 1217; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KA0 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 GAAVREVYEEAGVKGKLGRLLGIFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GAAVREVYEEAGVKGKLGRLLGIFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
130 140 150 160 170 180
>>NP_950241 (OMIM: 609229) diphosphoinositol polyphospha (181 aa)
initn: 654 init1: 637 opt: 1205 Z-score: 1504.2 bits: 284.9 E(85289): 4.8e-77
Smith-Waterman score: 1205; 99.4% identity (99.4% similar) in 181 aa overlap (1-180:1-181)
10 20 30 40 50 60
pF1KA0 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
10 20 30 40 50 60
70 80 90 100 110
pF1KA0 GAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_950 GAAVREVYEEAGVKGKLGRLLGIFEQNQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_950 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV
130 140 150 160 170 180
180
pF1KA0 R
:
NP_950 R
>>NP_060629 (OMIM: 300528) diphosphoinositol polyphospha (164 aa)
initn: 1023 init1: 543 opt: 1005 Z-score: 1256.2 bits: 238.9 E(85289): 3.1e-63
Smith-Waterman score: 1005; 90.8% identity (96.3% similar) in 163 aa overlap (2-163:1-163)
10 20 30 40 50 60
pF1KA0 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
:: ::::::::: :::::::::::::::.::::::::::::::.:::::::::::::::
NP_060 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPG
10 20 30 40 50
70 80 90 100 110
pF1KA0 GAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW
::::::::::::::::::::::.:: :::::::::::::::::.::::::::.:::::::
NP_060 GAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV
::::::::::::::::::::::::::: ::.:::: .:: ::..
NP_060 FKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
120 130 140 150 160
180
pF1KA0 R
>>NP_001291892 (OMIM: 300527) diphosphoinositol polyphos (164 aa)
initn: 995 init1: 542 opt: 995 Z-score: 1243.8 bits: 236.6 E(85289): 1.5e-62
Smith-Waterman score: 995; 90.2% identity (95.7% similar) in 163 aa overlap (2-163:1-163)
10 20 30 40 50 60
pF1KA0 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
:: ::::::::: :::::::::::::::.::::::::::::::.:::::::::::::::
NP_001 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPG
10 20 30 40 50
70 80 90 100 110
pF1KA0 GAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW
::::::::::::::::::::::.:: ::: :::::::::::::.::::::::.:::::::
NP_001 GAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV
::::::::::::::::::::::::::: ::.:::: .:: ::..
NP_001 FKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
120 130 140 150 160
180
pF1KA0 R
>>NP_694853 (OMIM: 300527) diphosphoinositol polyphospha (164 aa)
initn: 995 init1: 542 opt: 995 Z-score: 1243.8 bits: 236.6 E(85289): 1.5e-62
Smith-Waterman score: 995; 90.2% identity (95.7% similar) in 163 aa overlap (2-163:1-163)
10 20 30 40 50 60
pF1KA0 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
:: ::::::::: :::::::::::::::.::::::::::::::.:::::::::::::::
NP_694 MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPG
10 20 30 40 50
70 80 90 100 110
pF1KA0 GAAVREVYEEAGVKGKLGRLLGIFE-NQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREW
::::::::::::::::::::::.:: ::: :::::::::::::.::::::::.:::::::
NP_694 GAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 FKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSV
::::::::::::::::::::::::::: ::.:::: .:: ::..
NP_694 FKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
120 130 140 150 160
180
pF1KA0 R
>>XP_011536098 (OMIM: 609229) PREDICTED: diphosphoinosit (128 aa)
initn: 850 init1: 850 opt: 850 Z-score: 1065.0 bits: 203.1 E(85289): 1.4e-52
Smith-Waterman score: 850; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KA0 CLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG
::::::::::::::::::::::::::::::
XP_011 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG
10 20 30
90 100 110 120 130 140
pF1KA0 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
40 50 60 70 80 90
150 160 170 180
pF1KA0 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
::::::::::::::::::::::::::::::::::::::
XP_011 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
100 110 120
>>NP_001287953 (OMIM: 609229) diphosphoinositol polyphos (128 aa)
initn: 850 init1: 850 opt: 850 Z-score: 1065.0 bits: 203.1 E(85289): 1.4e-52
Smith-Waterman score: 850; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KA0 CLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG
::::::::::::::::::::::::::::::
NP_001 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG
10 20 30
90 100 110 120 130 140
pF1KA0 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
40 50 60 70 80 90
150 160 170 180
pF1KA0 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
::::::::::::::::::::::::::::::::::::::
NP_001 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
100 110 120
>>XP_011536097 (OMIM: 609229) PREDICTED: diphosphoinosit (128 aa)
initn: 850 init1: 850 opt: 850 Z-score: 1065.0 bits: 203.1 E(85289): 1.4e-52
Smith-Waterman score: 850; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KA0 CLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG
::::::::::::::::::::::::::::::
XP_011 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG
10 20 30
90 100 110 120 130 140
pF1KA0 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
40 50 60 70 80 90
150 160 170 180
pF1KA0 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
::::::::::::::::::::::::::::::::::::::
XP_011 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
100 110 120
>>NP_001287952 (OMIM: 609229) diphosphoinositol polyphos (128 aa)
initn: 850 init1: 850 opt: 850 Z-score: 1065.0 bits: 203.1 E(85289): 1.4e-52
Smith-Waterman score: 850; 100.0% identity (100.0% similar) in 128 aa overlap (53-180:1-128)
30 40 50 60 70 80
pF1KA0 CLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLG
::::::::::::::::::::::::::::::
NP_001 MEPEEEPGGAAVREVYEEAGVKGKLGRLLG
10 20 30
90 100 110 120 130 140
pF1KA0 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEK
40 50 60 70 80 90
150 160 170 180
pF1KA0 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
::::::::::::::::::::::::::::::::::::::
NP_001 LKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
100 110 120
>>NP_006694 (OMIM: 609228) diphosphoinositol polyphospha (172 aa)
initn: 845 init1: 845 opt: 845 Z-score: 1057.1 bits: 202.1 E(85289): 3.8e-52
Smith-Waterman score: 845; 79.1% identity (90.5% similar) in 158 aa overlap (1-158:1-158)
10 20 30 40 50 60
pF1KA0 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPG
:::.: ::::::: .:.::::::::::::.:.:::::::::.::.::::::::::::::.
NP_006 MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 GAAVREVYEEAGVKGKLGRLLGIFENQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWF
:::::: ::::::: ::::.::::::.:::::::::: :::.:::::::::::::::::
NP_006 VAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
:.:::::::: ::::.: :.: :. : : ::. .: .
NP_006 KIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMSGIR
130 140 150 160 170
180 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:42:53 2016 done: Thu Nov 3 19:42:54 2016
Total Scan time: 6.080 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]